EGFR-IN-7 |
| Catalog No.GC35966 |
EGFR-IN-7 is a potent, selective and orally active EGFR kinase inhibitor. EGFR-IN-7 has inhibitory effect for for EGFR (WT) and EGFR (mutant C797S/T790M/L858R) with IC50 values of 7.92 nM and 0.218 nM, respectively. EGFR-IN-7 shows anti-tumor activity. EGFR-IN-7 can be used for the research of various cancers.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2267329-76-8
Sample solution is provided at 25 µL, 10mM.
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EGFR-IN-7 (compound 34) is a selective and potent EGFR kinase inhibitor extracted from patent WO2019015655A1, has IC50s of 7.92 nM and 0.218 nM for EGFR (WT) and EGFR (mutant C797S/T790M/L858R) respectively, and shows anti-tumor activity[1]. EGFR (WT)|7.92 nM (IC50)|EGFR (C797S/T790M/L858R)|0.218 nM (IC50)
[1]. Aryl-phosphorus-oxygen compound as egfr kinase inhibitor.
Average Rating: 5 (Based on Reviews and 38 reference(s) in Google Scholar.)
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