Procyanidin B3 (Synonyms: (+)-Catechin-(4α→8)-(+)-catechin, Proanthocyanidin B3, Procyanidol B3) |
| Catalog No.GC36975 |
A polyphenol flavonoid dimer with diverse biological activities
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 23567-23-9
Sample solution is provided at 25 µL, 10mM.
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Procyanidin B3 is a natural product, acts as a specific HAT inhibitor, binds to the other site of p300 instead of the active site, selectively inhibits p300-mediated androgen receptor acetylation. Procyanidin B3 has no effect on HDAC or HMT (histone methyltransferase)[1]. p300[1]
[1]. Choi KC, et al. Procyanidin B3, an inhibitor of histone acetyltransferase, enhances the action of antagonist for prostate cancer cells via inhibition of p300-dependent acetylation of androgen receptor. Biochem J. 2011 Jan 1;433(1):235-44.
Average Rating: 5 (Based on Reviews and 13 reference(s) in Google Scholar.)
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