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TA 0910 acid-type

Catalog No.GC37712 Copy One-Click Copy Product Info

TA 0910 acid-type is a metabolite of TA 0910.

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TA 0910 acid-type Chemical Structure

Cas No.: 103300-77-2

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Sample solution is provided at 25 µL, 10mM.



Description of TA 0910 acid-type

TA 0910 acid-type is a metabolite of TA 0910. TA-0910 is a metabolically stable analogue of thyrotropin releasing hormone (TRH)[1].

[1]. Morikawa S, et al. Radioimmunoassay for TA-0910, a new stable thyrotropin releasing hormone analogue and its metabolite, TA-0910 acid-type, in human plasma and urine. J Pharm Biomed Anal. 1998 Apr;16(8):1267-74.

Chemical Properties of TA 0910 acid-type

Cas No. 103300-77-2 SDF
Canonical SMILES O=C([C@@H](N1)CC(N(C)C1=O)=O)N[C@@H](CC2=CNC=N2)C(N3[C@@H](CCC3)C(O)=O)=O
Formula C17H22N6O6 M.Wt 406.39
Solubility DMSO : 25 mg/mL (61.52 mM; ultrasonic and warming and heat to 60°C) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of TA 0910 acid-type

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.4607 mL 12.3035 mL 24.6069 mL
5 mM 492.1 μL 2.4607 mL 4.9214 mL
10 mM 246.1 μL 1.2303 mL 2.4607 mL
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In vivo Formulation Calculator (Clear solution) of TA 0910 acid-type

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Reviews

Review for TA 0910 acid-type

Average Rating: 5 ★★★★★ (Based on Reviews and 22 reference(s) in Google Scholar.)

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