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2-Methyl-5-HT Catalog No.GC38108

Size Price Stock Qty
10mM*1mL in DMSO
$61.00
In stock
5mg
$57.00
In stock
10mg
$102.00
In stock
25mg
$245.00
In stock
50mg
$459.00
In stock
100mg
$826.00
In stock

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Sample solution is provided at 25 µL, 10mM.

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Chemical Properties

Cas No. 78263-90-8 SDF Download SDF
Synonyms N/A
Chemical Name N/A
Canonical SMILES OC1=CC2=C(NC(C)=C2CCN)C=C1
Formula C11H14N2O M.Wt 190.24
Solubility DMSO: 125 mg/mL (657.06 mM) Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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Background

2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist. 2-Methyl-5-HT is shown to display anti-depressive-like effects[1].

2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) significantly decreases time of immobility thus showing anti-depressive-like effects[1]. Animal Model: Male Sprague-Dawley rats[1]

[1]. Sumaya IC, et al. Differential effects of a short-term high-fat diet in an animal model of depression in rats treated with the 5-HT3 receptor antagonist, ondansetron, the 5-HT3 receptor agonist, 2-methyl-5-HT, and the SSRI, fluoxetine. Pharmacol Biochem Behav. 2016 May;144:78-84.