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Neurodazine Catalog No.GC38522

Small molecule inducer of neuronal differentiation

Size Price Stock Qty
1mg
$183.00
In stock
5mg
$541.00
In stock
10mg
$918.00
In stock

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Sample solution is provided at 25 µL, 10mM.

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Chemical Properties

Cas No. 937807-66-4 SDF Download SDF
Synonyms N/A
Chemical Name N/A
Canonical SMILES COC1=CC=C(C2=C(C3=CC=C(OC)C=C3)N=C(C4=CC=C(C5=CC=CC(Cl)=C5)O4)N2)C=C1
Formula C27H21ClN2O3 M.Wt 456.92
Solubility DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 10 mg/ml Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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Background

Neurodazine is an imidazole-based small molecule, serve as a promoter of neurogenesisin pluripotent cells. Neurodazine promotes neurogenesis by activating Wnt and Shh signaling pathways. Neurodazine selectively suppresses astrocyte differentiation of P19 cells[1][2].

[1]. Kim GH, et al. Imidazole-based small molecules that promote neurogenesis in pluripotent cells. Angew Chem Int Ed Engl. 2014 Aug 25;53(35):9271-4. [2]. Halder D, et al. Synthetic small molecules that induce neuronal differentiation in neuroblastoma and fibroblast cells. Mol Biosyst. 2015 Oct;11(10):2727-37.