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Home >> Signaling Pathways >> Chromatin/Epigenetics >> PAD

PAD

Products for  PAD

  1. Cat.No. Product Name Information
  2. GC35480 BB-Cl-Amidine hydrochloride BB-Cl-Amidine hydrochloride is a peptidylarginine deminase (PAD) inhibitor. BB-Cl-Amidine hydrochloride Chemical Structure
  3. GC42910 BB-F-Yne BB-F-Yne is a cell-permeable derivative of the protein arginine diminase (PAD) inhibitor BB-Cl-amidine that contains an alkyne moiety for use in click chemistry reactions. BB-F-Yne Chemical Structure
  4. GC48495 BMS-P5 BMS-P5 is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor. BMS-P5 blocks MM-induced NET formation and delays progression of MM in a syngeneic mouse model. BMS-P5 Chemical Structure
  5. GC43202 CAY10723

    AFM30a, AMF30a

     CAY10723 is a potent protein arginine deiminase 2 (PAD2) inhibitor and has excellent PAD2-selectivity. CAY10723 Chemical Structure
  6. GC90710 CAY10723 (hydrochloride)

    A PAD2 inhibitor

     CAY10723 (hydrochloride) Chemical Structure
  7. GC47050 CAY10727 A PAD3 inhibitor CAY10727 Chemical Structure
  8. GC45402 CAY10729 (trifluoroacetate salt) (technical grade)   CAY10729 (trifluoroacetate salt) (technical grade) Chemical Structure
  9. GC35706 Cl-amidine

    Cl-amidine (N-α-benzoyl-N5-(2-chloro-1-iminoethyl)-l-ornithine amide), is a PAD4 inactivator with enhanced potency.

     Cl-amidine Chemical Structure
  10. GC18925 Cl-Amidine (hydrochloride) Cl-amidine is an inhibitor of protein arginine deiminases (PAD; IC50s = 0.8, 6.2, and 5.9 uM for PAD1, PAD3, and PAD4 in vitro, respectively). Cl-Amidine (hydrochloride) Chemical Structure
  11. GC11032 Cl-Amidine (trifluoroacetate salt) Cl-Amidine (trifluoroacetate salt) is a multi-targeting peptidylarginine deminase (PAD) inhibitor with the functional group RC(NR)NR2 that inhibits PAD1 (IC50=0.8μM), PAD3 (IC50=6.2μM), and PAD4 (IC50=5.9μM) with 15min half-time. Cl-Amidine (trifluoroacetate salt) Chemical Structure
  12. GC43651 F-Amidine (trifluoroacetate salt) F-amidine is an inhibitor of protein arginine deiminases (PADs) that is selective for PAD1 and PAD4 (IC50s = 29.5, 350, and 21.6 μM for PAD1, PAD3, and PAD4 in vitro, respectively). F-Amidine (trifluoroacetate salt) Chemical Structure
  13. GC43788 GSK121 (trifluoroacetate salt) GSK-121 Trifluoroacetates a selective PAD4 inhibitor. GSK121 (trifluoroacetate salt) Chemical Structure
  14. GC43789 GSK199 (hydrochloride) GSK199 (hydrochloride) is a reversible and selective PAD4 inhibitor with an IC50 of 200 nM in the absence of calcium. GSK199 (hydrochloride) Chemical Structure
  15. GC91565 GSK199 analog (hydrochloride) GSK199 analog is an inhibitor of peptidyl arginine deiminase 4 (PAD4) and a derivative of the PAD4 inhibitor GSK199. GSK199 analog (hydrochloride) Chemical Structure
  16. GC19184 GSK484 hydrochloride GSK484 is a selective PAD4 inhibitor, has been used as an anti-ischemic compound and exerts inhibitory activity against PAD4. GSK484 hydrochloride Chemical Structure
  17. GC45548 Photoswitchable PAD Inhibitor (technical grade)   Photoswitchable PAD Inhibitor (technical grade) Chemical Structure
  18. GC32303 Streptonigrin (Bruneomycin)

    NSC 45383, NSC 56748, NSC 83950

     Streptonigrin (Bruneomycin) (Bruneomycin), a natural product produced by Streptomyces flocculus, possesses both anti-tumor and anti-bacterial activity. Streptonigrin (Bruneomycin) Chemical Structure
  19. GC45005 TDFA (trifluoroacetate salt)

    Thr-Asp-F-amidine

     TDFA (trifluoroacetate salt) Chemical Structure
  20. GC33261 YW3-56 YW3-56 Chemical Structure
  21. GC48263 YW3-56 (hydrochloride) (technical grade) A PAD2 and PAD4 inhibitor YW3-56 (hydrochloride) (technical grade) Chemical Structure

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