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Home >> Signaling Pathways >> Others >> Nucleic Acid Turnover/Signaling

Nucleic Acid Turnover/Signaling

Products for  Nucleic Acid Turnover/Signaling

  1. Cat.No. Product Name Information
  2. GC41717 (R)-Gyramide A (hydrochloride)

    (R)-534F6

     (R)-Gyramide A is a bacterial DNA gyrase inhibitor that disrupts supercoiling activity with an IC50 value of 3.3 μM. (R)-Gyramide A (hydrochloride) Chemical Structure
  3. GC49337 4-Acetamidobenzenesulfonamide

    APAS, N-Acetyl p-Aminobenzene Sulfonamide, N4-Acetyl Sulfanilamide, N-Acetylsulfanilamide, NSC 217, NSC 406839

     A metabolite of asulam and sulfanilamide 4-Acetamidobenzenesulfonamide Chemical Structure
  4. GC42545 5-Fluorouracil-13C,15N2

    5-FU-13C,15N2

     5-Fluorouracil-13C,15N2 is intended for use as an internal standard for the quantification of 5-flurouracil by GC- or LC-MS. 5-Fluorouracil-13C,15N2 Chemical Structure
  5. GC40479 6-Aminophenanthridine

    6AP

     6-Aminophenanthridine is an antiprion agent. 6-Aminophenanthridine Chemical Structure
  6. GC42578 6-Formylpterin

    2-Amino-6-formylpteridin-4-one, 6-FP, Pterin-6-aldehyde

     Xanthine oxidase (XO) generates reactive oxygen species, including hydrogen peroxide (H2O2), as it oxidizes specific substrates in the presence of water and oxygen. 6-Formylpterin Chemical Structure
  7. GC49235 6-Methylmercaptopurine

    6-MMP, 6-(Methylthio)purine, NSC 20105, SQ 8,343

     A metabolite of 6-mercaptopurine 6-Methylmercaptopurine Chemical Structure
  8. GC49488 6-Methylmercaptopurine-d3

    6-MMP-d3, 6-(Methylthio)purine-d3

     An internal standard for the quantification of 6-MMP 6-Methylmercaptopurine-d3 Chemical Structure
  9. GC18426 8-Nitroguanine 8-Nitroguanine is a nitrative guanine derivative formed by oxidative damage to the guanine base in DNA by reactive nitrogen species (RNS) during inflammation and in vitro by reaction of DNA with peroxynitrite and other RNS reagents. 8-Nitroguanine Chemical Structure
  10. GC49347 8Br-HA An FHIT inhibitor 8Br-HA Chemical Structure
  11. GC42644 9-Deazaguanine

    NSC 344522

     9-Deazaguanine is an analog of guanine that acts as an inhibitor of purine nucleoside phosphorylase (PNP; Kd = 160 nM). 9-Deazaguanine Chemical Structure
  12. GC90794 Adenosine 5'-methylenediphosphate (sodium salt)

    An inhibitor of ecto-5’-nucleotidase

     Adenosine 5'-methylenediphosphate (sodium salt) Chemical Structure
  13. GC49285 Adenosine 5’-methylenediphosphate (hydrate)

    Adenosine 5'-(α,β-methylene)diphosphate, AMP-CP, APCP, 5'-APCP

     An inhibitor of ecto-5’-nucleotidase Adenosine 5’-methylenediphosphate (hydrate) Chemical Structure
  14. GC46806 Adenosine 5'-diphosphate (potassium salt hydrate)

    5'-ADP, ADP

     A neuropeptide with diverse biological activities Adenosine 5'-diphosphate (potassium salt hydrate) Chemical Structure
  15. GC49039 Althiomycin

    NSC 102809

     A thiazole antibiotic Althiomycin Chemical Structure
  16. GC42783 Ametantrone

    NSC 196473, NSC 290813

     Ametantrone (NSC 196473) is an antitumor agent that intercalates into DNA and induces topoisomerase II (TOP2)-mediated DNA break. Ametantrone Chemical Structure
  17. GC46895 Aurintricarboxylic Acid (ammonium salt)

    ATA

     A protein synthesis inhibitor with diverse biological activities Aurintricarboxylic Acid (ammonium salt) Chemical Structure
  18. GC18322 CAY10567

    BML257

     Akt1, 2, and 3 are serine/threonine protein kinases in the phosphatidylinositol 3 (PI3)-kinase signalling pathway that play a critical role in the regulation of cell proliferation and survival. CAY10567 Chemical Structure
  19. GC40219 Ciprofloxacin-d8 (hydrochloride) Ciprofloxacin-d8 is intended for use as an internal standard for the quantification of ciprofloxacin by GC- or LC-MS. Ciprofloxacin-d8 (hydrochloride) Chemical Structure
  20. GC47128 CU-32 A cGAS inhibitor CU-32 Chemical Structure
  21. GC47129 CU-76 A cGAS inhibitor CU-76 Chemical Structure
  22. GC47142 Cycloguanil-d6 (hydrochloride)

    Chloroguanide Triazine-d6

     A neuropeptide with diverse biological activities Cycloguanil-d6 (hydrochloride) Chemical Structure
  23. GC49100 Desmethyl Ofloxacin (hydrochloride) A metabolite of ofloxacin Desmethyl Ofloxacin (hydrochloride) Chemical Structure
  24. GC47228 Dihydronovobiocin A coumarin antibiotic Dihydronovobiocin Chemical Structure
  25. GC40300 Dihydroresveratrol Dihydroresveratrol is a major metabolite of resveratrol that is produced by animal-associated bacteria, including the gut microbiota. Dihydroresveratrol Chemical Structure
  26. GC45881 Docosanoic Acid-d43

    Behenic Acid-d43, C22:0-d43, DCA-d43

     An internal standard for the quantification of docosanoic acid Docosanoic Acid-d43 Chemical Structure
  27. GC49288 Dolutegravir M1 A metabolite of dolutegravir Dolutegravir M1 Chemical Structure
  28. GC49289 Dolutegravir O-β-D-Glucuronide

    Dolutegravir Glucuronide, DTG Glucuronide

     A metabolite of dolutegravir Dolutegravir O-β-D-Glucuronide Chemical Structure
  29. GC45440 Doxycycline-d3 (hyclate)

     An internal standard for quantifying doxycycline

     Doxycycline-d3 (hyclate) Chemical Structure
  30. GC48664 Enoxacin-d8 (hydrochloride) Enoxacin-d8 (hydrochloride) Chemical Structure
  31. GC49101 Enrofloxacin-d5

    BAY-Vp 2674-d5, ENR-d5

     An internal standard for the quantification of enrofloxacin Enrofloxacin-d5 Chemical Structure
  32. GC49165 GS-441524 tris-isobutyryl ester

    GS-441524 tris-isobutyryl ester

     A prodrug form of GS-441524 GS-441524 tris-isobutyryl ester Chemical Structure
  33. GC91775 h-e5'NT Inhibitor 5C

    Human Ecto-5'-nucleotidase Inhibitor 5C

     h-e5'NT Inhibitor 5C is an inhibitor of ecto-5'-nucleotidase, also known as CD73 (IC50s = 0.37 and 1.66 µM for the human and rat enzymes, respectively). h-e5'NT Inhibitor 5C Chemical Structure
  34. GC47552 Leflunomide-d4 An internal standard for the quantification of leflunomide Leflunomide-d4 Chemical Structure
  35. GC45886 Levofloxacin-d8 (hydrochloride) A neuropeptide with diverse biological activities Levofloxacin-d8 (hydrochloride) Chemical Structure
  36. GC61002 Lomibuvir

    VX-222

     An HCV polymerase inhibitor Lomibuvir Chemical Structure
  37. GC47649 Methotrexate (hydrate)

    Amethopterin, CL 14,377, EMT 25299, MTX, NSC 740, R 9985

     A folic acid and aminopterin derivative Methotrexate (hydrate) Chemical Structure
  38. GC18769 MST-312

    Telomerase Inhibitor IX

     MST312 is a telomerase inhibitor (IC50 = 0.67 μM in a TRAP assay). MST-312 Chemical Structure
  39. GC91397 N-desmethyl Levofloxacin (hydrochloride)

    Desmethyl Levofloxacin

     N-desmethyl Levofloxacin is an active metabolite of the fluoroquinolone antibiotic levofloxacin . N-desmethyl Levofloxacin (hydrochloride) Chemical Structure
  40. GC40081 Nargenicin

    Antibiotic 47444

    Nargenicin is a macrolide antibiotic that selectively inhibits the growth of S.

     Nargenicin Chemical Structure
  41. GC48565 Ofloxacin-d8 (hydrochloride)

    Hoe-280-d8 hydrochloride

     Ofloxacin-d8 (hydrochloride) Chemical Structure
  42. GC47817 Olaparib-d4 A neuropeptide with diverse biological activities Olaparib-d4 Chemical Structure
  43. GC48933 Oxonic Acid-13C2,15N3 (potassium salt hydrate)

    Allantoxanic Acid-13C2,15N3, Potassium oxonate-13C2,15N3

     Oxonic Acid-13C2,15N3 (potassium salt hydrate) Chemical Structure
  44. GC44591 Pemetrexed (sodium salt hydrate) Pemetrexed (sodium salt hydrate) is a novel antifolate, the Ki values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively. Pemetrexed (sodium salt hydrate) Chemical Structure
  45. GC47933 Pemetrexed-13C5 (sodium salt hydrate) A neuropeptide with diverse biological activities Pemetrexed-13C5 (sodium salt hydrate) Chemical Structure
  46. GC90883 Purine riboside-5'-O-triphosphate (sodium salt)

    An active metabolite of nebularine

     Purine riboside-5'-O-triphosphate (sodium salt) Chemical Structure
  47. GC48050 Rifapentine-d9

    Cyclopentylrifampicin-d9

     A neuropeptide with diverse biological activities Rifapentine-d9 Chemical Structure
  48. GC48055 Riociguat-13C-d3

    BAY 632521-13C,d3

     A neuropeptide with diverse biological activities Riociguat-13C-d3 Chemical Structure
  49. GC49188 Sarafloxacin-d8 (hydrochloride)

    A-56620-d8 hydrochloride

     An internal standard for the quantification of sarafloxacin Sarafloxacin-d8 (hydrochloride) Chemical Structure
  50. GC62393 SU0268 SU0268 is a potent and specific inhibitor of 8-Oxoguanine DNA glycosylase 1 (OGG1). SU0268 Chemical Structure
  51. GC48116 Sulfamethizole-d4

    N1-(5-Methyl-1,3,4-thiadiazol-2-yl)sulfanilamide-d4

     A neuropeptide with diverse biological activities Sulfamethizole-d4 Chemical Structure
  52. GC48143 Tenofovir-d6

    GS-1275-d6, GS-1278-d6, (R)-PMPA-d6, TDF-d6

     An internal standard for the quantification of tenofovir Tenofovir-d6 Chemical Structure
  53. GC40240 Tigecycline-d9

    GAR-936-d9

     Tigecycline-d9 is intended for use as an internal standard for the quantification of tigecycline by GC- or LC-MS. Tigecycline-d9 Chemical Structure
  54. GC48205 Trimethoprim-d3 An internal standard for the quantification of trimethoprim Trimethoprim-d3 Chemical Structure
  55. GC45088 Trimethoprim-PEG-amine (trifluoroacetate salt) Trimethoprim is an antibiotic that inhibits dihydrofolate reductase (DHFR) and shows selectivity for bacterial DHFR over mammalian DHFR (IC50s = 5 and 30,000 nM, respectively). Trimethoprim-PEG-amine (trifluoroacetate salt) Chemical Structure
  56. GC90683 ZM 522

    An inhibitor of ecto-5’-nucleotidase

     ZM 522 Chemical Structure
  57. GC19807 β-Amanitin β-Amanitin is a cyclic peptide toxin in the poisonous Amanita phalloides mushroom. β-Amanitin inhibits inhibits eukaryotic RNA polymerase II and III. β-Amanitin inhibits protein synthesis. β-Amanitin can be used as a cytotoxic component of antibody-drug conjugates (ADCs). β-Amanitin Chemical Structure

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