SDZ285428 |
| Catalog No.GC61465 |
SDZ285428 is a CYP51 inhibitor.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 174262-13-6
Sample solution is provided at 25 µL, 10mM.
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SDZ285428 is a CYP51 inhibitor. SDZ285428 inhibits Trypanosoma cruzi (TC) CYP51 with I/E2 <1 (5 min) and I/E2=9 (1 h). SDZ285428 inhibits Trypanosoma brucei (TB) CYP51 with I/E2 <1 (5 min) and I/E2=35 (1 h)[1].
Specific inhibition of protozoan CYP51 can potentially provide treatment for human trypanosomiases[1].
[1]. Lepesheva GI, et al. CYP51: A major drug target in the cytochrome P450 superfamily. Lipids. 2008 Dec;43(12):1117-25.
Average Rating: 5 (Based on Reviews and 11 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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