SGC AAK1 1 |
| Catalog No.GC50487 |
AAK1 and BMP2K inhibitor; activates Wnt signaling
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2247894-32-0
Sample solution is provided at 25 µL, 10mM.
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Adaptor-associated protein kinase 1 (AAK1) and BMP-2-inducible protein kinase (BMP2K) inhibitor (IC50 values are 233 nM and 1.48 μM for AAK1 and BMP2K, respectively). Inhibits AAK1-dependent phosphorylation of AP2M1. Activates Wnt signaling.
Agajanian et al (2018) AAK1 inhibits WNT signaling by promoting clathrin-mediated endocytosis of LRP6. View pre-publication manuscript.
Average Rating: 5 (Based on Reviews and 10 reference(s) in Google Scholar.)
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