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Thaxtomin A

Catalog No.GC18697

Thaxtomin A is a major phytotoxin produced by S.

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Thaxtomin A Chemical Structure

Cas No.: 122380-18-1

Size Price Stock Qty
1mg
$340.00
In stock
5mg
$1,087.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

Thaxtomin A is a major phytotoxin produced by S. scabies, gram-positive soil bacterium responsible for producing scabs on tubers and root vegetables. [1] This bacterial metabolite acts as a virulence factor in the common scab potato disease and demonstrates herbicidal activity against the dicotyledon weeds B. campestris and A. retroflexus.[2]

Reference:
[1]. Lerat, S., Simao-Beaunoir, A.M., Wu, R., et al. Involvement of the plant polymer suberin and the disaccharide cellobiose in triggering thaxtomin A biosynthesis, a phytotoxin produced by the pathogenic agent Streptomyces scabies. Phytopathology 100(1), 91-96 (2010).
[2]. Zhang, H., Ning, X., Hang, H., et al. Total synthesis of thaxtomin A and its stereoisomers and findings of their biological activities. Organic Letters 15(22), 5670-5673 (2013).

Chemical Properties

Cas No. 122380-18-1 SDF
Chemical Name (3R,6S)-3-hydroxy-3-[(3-hydroxyphenyl)methyl]-1,4-dimethyl-6-[(4-nitro-1H-indol-3-yl)methyl]-2,5-piperazinedione
Canonical SMILES O=C(N(C)[C@H]1CC2=CNC3=C2C([N+]([O-])=O)=CC=C3)[C@@](CC4=CC=CC(O)=C4)(O)N(C)C1=O
Formula C22H22N4O6 M.Wt 438.4
Solubility DMF: Soluble,DMSO: Soluble,Ethanol: Partially soluble,Methanol: Partially soluble Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 2.281 mL 11.4051 mL 22.8102 mL
5 mM 0.4562 mL 2.281 mL 4.562 mL
10 mM 0.2281 mL 1.1405 mL 2.281 mL
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Average Rating: 5 ★★★★★ (Based on Reviews and 13 reference(s) in Google Scholar.)

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