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Hydrolyzed Fumonisin B1 (Synonyms: Aminopentol)

Catalog No.GC36270

Hydrolyzed Fumonisin B1 (Aminopentol) is the backbone and main hydrolysis product of the mycotoxin Fumonisin B1.

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Hydrolyzed Fumonisin B1 Chemical Structure

Cas No.: 145040-09-1

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Hydrolyzed Fumonisin B1 (Aminopentol) is the backbone and main hydrolysis product of the mycotoxin fumonisin B1 (FB1), can weakly inhibit ceramide synthase[1].

[1]. Collins TF, et al. Effects of aminopentol on in utero development in rats. Food Chem Toxicol. 2006 Feb;44(2):161-9. [2]. Humpf HU, et al. Acylation of naturally occurring and synthetic 1-deoxysphinganines by ceramide synthase. Formation of N-palmitoyl-aminopentol produces a toxic metabolite of hydrolyzed fumonisin, AP1, and a new category of ceramide synthase inhibitor. J Biol Chem. 1998 Jul 24;273(30):19060-4. [3]. Schmelz EM, et al. Induction of apoptosis by fumonisin B1 in HT29 cells is mediated by the accumulation of endogenous free sphingoid bases. Toxicol Appl Pharmacol. 1998 Feb;148(2):252-60.

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