KS 176 |
| Catalog No.GC14688 |
inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1253452-78-6
Sample solution is provided at 25 µL, 10mM.
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KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter (IC50 values are 0.59 and 1.39 μM in Pheo A and Hoechst 33342 assays respectively). Displays no inhibitory activity against P-gp or MRP1.IC50 value: 0.59( in Pheo A assay), 1.39 μM (in Hoechst 33342 assay).Target: BCRPThe more detailed information please refer to Compound 9 in the reference.
References:
[1]. Pick A, et al. Specific inhibitors of the breast cancer resistance protein (BCRP). ChemMedChem. 2010 Sep 3;5(9):1498-505.
Average Rating: 5 (Based on Reviews and 10 reference(s) in Google Scholar.)
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