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Home >> Signaling Pathways >> Membrane Transporter/Ion Channel >> GTPase

GTPase

Products for  GTPase

  1. Cat.No. Product Name Information
  2. GC40452 15(S)-HETE MaxSpec® Standard 15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. 15(S)-HETE MaxSpec® Standard Chemical Structure
  3. GC11483 8-CPT-2Me-cAMP, sodium salt

    8-CPT-2MecAMP, 8-pCPTcAMP, 8-pCPT-2′-OMe-cAMP

     8-CPT-2Me-cAMP, sodium salt is a selective activator of exchange proteins activated by cAMP (Epac), the cAMP sensitive guanine nucleotide exchange factors (GEFs) for the small GTPases Rap1 and Rap2. 8-CPT-2Me-cAMP, sodium salt Chemical Structure
  4. GC18426 8-Nitroguanine 8-Nitroguanine is a nitrative guanine derivative formed by oxidative damage to the guanine base in DNA by reactive nitrogen species (RNS) during inflammation and in vitro by reaction of DNA with peroxynitrite and other RNS reagents. 8-Nitroguanine Chemical Structure
  5. GC16199 8-pCPT-2-O-Me-cAMP-AM Epac activator 8-pCPT-2-O-Me-cAMP-AM Chemical Structure
  6. GC39810 CID44216842

    Cdc42-IN-1

     CID44216842 (Cdc42-IN-1) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 0.3 and 0.5 μM in GDP binding assay, respectively. Use as a molecular probe. CID44216842 Chemical Structure
  7. GC43306 Compound C108 Compound C108 is an inhibitor of the GTPase-activating protein (SH3 domain)-binding protein 2 (G3BP2), which is involved in breast tumor initiation. Compound C108 Chemical Structure
  8. GC91590 DTPD-Q

    2,5-Bis(o-tolylamino)cyclohexa-2,5-diene-1,4-dione,DTPD-quinone

     DTPD-Q is an oxidized derivative of the antioxidant and methylphenyl substituted p-phenylenediamine DTPD. DTPD-Q Chemical Structure
  9. GC14179 Dynole 34-2 Dynamin I inhibitor Dynole 34-2 Chemical Structure
  10. GC20107 Fendiline hydrochloride

    Fendiline hydrochloride is a nonselective calcium channel blocker.

     Fendiline hydrochloride Chemical Structure
  11. GC49089 FR900359

    UBO-QIC

     FR900359 is an inhibitor of G proteins Gαq, Gα11, and Gα14 with IC50 values of 13.18, 10.47, and 10nM, respectively and is isolated from the leaves of the ornamental plant Ardisia crenata FR900359 Chemical Structure
  12. GC18260 FTase Inhibitor I

    Farnesyltransferase Inhibitor I

     FTase inhibitor I is a potent inhibitor of farnesyltransferase (FTase; IC50 = 21 nM) that is greater than 30-fold selective for FTase over geranylgeranyl transferase (GGTase; IC50 = 790 nM). FTase Inhibitor I Chemical Structure
  13. GC52503 FTase Inhibitor II (trifluoroacetate salt)

    Farnesyltransferase Inhibitor II, FTI-II

     A potent, selective inhibitor of farnesyltransferase FTase Inhibitor II (trifluoroacetate salt) Chemical Structure
  14. GC90919 Guanosine 5'-[γ-thio]triphosphate (sodium salt)

    A hydrolysis-resistant analog of GTP

     Guanosine 5'-[γ-thio]triphosphate (sodium salt) Chemical Structure
  15. GC49033 Guanosine 5’-diphosphate (sodium salt hydrate)

    GDP

     A purine nucleotide Guanosine 5’-diphosphate (sodium salt hydrate) Chemical Structure
  16. GC49703 Guanosine 5’-[γ-thio]triphosphate (lithium salt)

    GTPγS, Guanosine 5'-O-(3-thio)triphosphate, Guanosine 5'-trihydrogen diphosphate monoanhydride Phosphorothioic Acid

     A hydrolysis-resistant analog of GTP Guanosine 5’-[γ-thio]triphosphate (lithium salt) Chemical Structure
  17. GC17852 Gue 1654

    Oxoeicosanoid receptor 1 (OXE-R) modulator

     Gue 1654 Chemical Structure
  18. GC15722 HJC 0350 EPAC2 antagonist, potent and selective HJC 0350 Chemical Structure
  19. GC47477 JKE-1674 A GPX4 inhibitor and active metabolite of ML-210 JKE-1674 Chemical Structure
  20. GC47478 JKE-1716 A GPX4 inhibitor JKE-1716 Chemical Structure
  21. GC44020 L-681,217 L-681,217 is an antibiotic originally isolated from S. L-681,217 Chemical Structure
  22. GC47601 Mastoparan (trifluoroacetate salt) A neuropeptide with diverse biological activities Mastoparan (trifluoroacetate salt) Chemical Structure
  23. GC52250 Mevalonate (lithium salt)

    Mevalonic Acid, MVA, Pentanoic Acid

     An intermediate in the mevalonate pathway Mevalonate (lithium salt) Chemical Structure
  24. GC13243 MitMAB

    TTABr, TTAB

     MitMAB, an organic building block, is a cationic surfactant with asymmetrical structure. MitMAB Chemical Structure
  25. GC18445 N-Deacetylcolchicine

    NSC 201400

     An inhibitor of microtubule polymerization N-Deacetylcolchicine Chemical Structure
  26. GC11880 OctMAB Dynamin inhibitor OctMAB Chemical Structure
  27. GC44506 Oligomycin D

    26-Demethyloligomycin A

    Oligomycin D is a macrolide antibiotic produced by several species of Streptomyces that inhibits the mitochondrial F1FO-ATPase and is used to uncouple oxidative phosphorylation from electron transport.

     Oligomycin D Chemical Structure
  28. GC44763 PtdIns-(4,5)-P2 (1,2-dioctanoyl) (sodium salt)

    DOPI4,5P2, Phosphatidylinositol4,5bisphosphate C8

     The phosphatidylinositol (PtdIns) represent a small percentage of total membrane phospholipids. PtdIns-(4,5)-P2 (1,2-dioctanoyl) (sodium salt) Chemical Structure
  29. GC48094 Spiro-Oxanthromicin A A polyketide Spiro-Oxanthromicin A Chemical Structure
  30. GC91153 Sulfonadyn-47

    A dynamin inhibitor

     Sulfonadyn-47 Chemical Structure

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