Nuclear Receptors

Cat.No. Product Name Information

GC10908 AC 45594 inverse agonist of steroidogenic factor 1 (SF-1) AC 45594 Chemical Structure

GC13937 BIM5078

HNF4α antagonist

GC14047 DLPC

1,2Dilauroylsnglycero3Phosphocholine, 1,2-DLPC

DLPC (DLPC) is an LRH-1 agonist ligand. DLPC Chemical Structure

GC10715 GSK 4112

SR6452

Rev-Erbα agonist GSK 4112 Chemical Structure

GC17658 Guggulsterone Guggulsterone is a plant sterol extracted from the resin of the plant Commiphora wightii. Guggulsterone can inhibit the growth of a wide variety of tumor cells and induce apoptosis through downregulation of antiapoptotic gene products (IAP1, xIAP, Bfl-1/A1, Bcl-2, cFLIP, and survivin), modulation of cell cycle proteins (such as Cyclin D1 and c-Myc), activation of caspases, inhibition of Akt, and activation of JNK. Guggulsterone Chemical Structure

GC10987 SID 7969543 Selective steroidogenic factor-1 (SF-1, NR5A1) inhibitor SID 7969543 Chemical Structure

GC15009 SR 1001 RORα and γ inverse agonist SR 1001 Chemical Structure

GC14284 SR 2211 inverse agonist of RORγ, potent and selective SR 2211 Chemical Structure

GC15275 SR 8278 SR 8278 is an antagonist of the nuclear receptor REV-ERBα that can inhibit the transcription of REV-ERBα with an EC₅₀ value of 0.47μM. SR 8278 Chemical Structure

GC12035 SR9009

REV-ERB Agonist II

SR9009 is a potent REV-ERBα/β agonist with EC₅₀ values of 0.67µM and 0.8μM for REV-ERBα and REV-ERBβ, respectively. SR9009 Chemical Structure

GC17310 SR9011 REV-ERB-α/β agonist SR9011 Chemical Structure

GC10195 Z-Guggulsterone Z-Guggulsterone is a steroidal plant active ingredient derived from Commiphora mukul and can promote cancer cell apoptosis. Z-Guggulsterone Chemical Structure

GC17515 Δ4-Dafachronic Acid

3-keto-4-Cholestenoic Acid

DAF-12 activator Δ4-Dafachronic Acid Chemical Structure

Products for Nuclear Receptors