Fungal
An antifungal agent is a drug that selectively eliminates fungal pathogens from a host with minimal toxicity to the host. Classes: 1. Polyene Antifungal Drugs: Amphotericin, nystatin, and pimaricin interact with sterols in the cell membrane (ergosterol in fungi, cholesterol in humans) to form channels through which small molecules leak from the inside of the fungal cell to the outside. 2. Azole Antifungal Drugs: Fluconazole, itraconazole, and ketoconazole inhibit cytochrome P450-dependent enzymes (particularly C14-demethylase) involved in the biosynthesis of ergosterol, which is required for fungal cell membrane structure and function. 3. Allylamine and Morpholine Antifungal Drugs: lylamines (naftifine, terbinafine) inhibit ergosterol biosynthesis at the level of squalene epoxidase. The morpholine drug, amorolfine, inhibits the same pathway at a later step. 4. Antimetabolite Antifungal Drugs: 5-Fluorocytosine acts as an inhibitor of both DNA and RNA synthesis via the intracytoplasmic conversion of 5-fluorocytosine to 5-fluorouracil.
Targets for Fungal
Products for Fungal
- Cat.No. Product Name Information
- GC45135 Validamycin A Validamycin A is an antifungal agent used to protect rice plants against sheath blight caused by the pathogenic fungus, R.
- GC32321 Vibunazole (BAY-N-7133)
- GC38979 Vincetoxicoside B Vincetoxicoside B shows antifungal activity.
- GC45147 Viridicatol Viridicatol is a fungal metabolite that has been found in various Penicillium species as well as Phoma.
- GC13079 Voriconazole A triazole antifungal agent
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GC70126
Voxvoganan
Voxvoganan (LTX-109) is a local antimicrobial agent that is highly effective against S. aureus, with an MIC of 2-4 μg/mL. Voxvoganan can be used in the research of bacterial skin infections and fungal infections.
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GC70127
Voxvoganan trihydrochloride
Voxvoganan (LTX-109) trihydrochloride is a local antimicrobial agent that is highly effective against S. aureus, with an MIC of 2-4 μg/mL. Voxvoganan trihydrochloride can be used in the research of bacterial skin infections and fungal infections.
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GC70133
VT-1598
VT-1598 is an orally effective and selective antifungal agent that targets CYP51. It has antifungal activity against Candida albicans.
- GC39116 Xanthoxylin Xanthoxylin (Xanthoxyline) is isolated from Zanthoxylum simulans.
- GC32322 Xanthyletin A coumarin
- GC16453 Zinc Pyrithione Proton pump inhibitor