MEGA-8 (Synonyms: N-octanoyl-N-Methylglucamine) |
| Catalog No.GC44152 |
MEGA-8 is a nonionic detergent that can be used to solubilize membrane proteins.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 85316-98-9
Sample solution is provided at 25 µL, 10mM.
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MEGA-8 is a nonionic detergent that can be used to solubilize membrane proteins. [1] It has a critical micelle concentration (CMC) of 70 mM under no-salt conditions and CMCs ranging from 5 to 64 mM under high and low salt conditions for a variety of salts. [2]
Reference:
[1]. Ko, J.-S., Oh, S.-W., Kim, K.-W., et al. Blending effects on adsorption and micellization of different membrane protein solubilizers: A thermodynamic study on three mixed systems of CHAPS with MEGA-8, -9 and -10 in pH 7.2 phosphate buffer solution. Colloids Surf. B Biointerfaces 45(2), 90-103 (2005).
[2]. Miyagishi, S., Okada, K., and Asakawa, T. Salt effect on critical micelle concentrations of nonionic surfactants, N-acyl-N-methylglucamides (MEGA-n). J. Colloid. Interface Sci. 238(1), 91-95 (2001).
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