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Signaling Pathways

The antibody-drug conjugate (ADC), a humanized or human monoclonal antibody conjugated with highly cytotoxic small molecules (payloads) through chemical linkers, is a novel therapeutic format and has great potential to make a paradigm shift in cancer chemotherapy. The three components of the ADC together give rise to a powerful oncolytic agent capable of delivering normally intolerable cytotoxins directly to cancer cells, which then internalize and release the cell-destroying drugs. At present, two ADCs, Adcetris and Kadcyla, have received regulatory approval with >40 others in clinical development.

ADCs are administered intravenously in order to prevent the mAb from being destroyed by gastric acids and proteolytic enzymes. The mAb component of the ADC enables it to circulate in the bloodstream until it finds and binds to tumor-specific cell surface antigens present on target cancer cells. Linker chemistry is an important determinant of the safety, specificity, potency and activity of ADCs. Linkers are designed to be stable in the blood stream (to conform to the increased circulation time of mAbs) and labile at the cancer site to allow rapid release of the cytotoxic drug. First generation ADCs made use of early cytotoxins such as the anthracycline, doxorubicin or the anti-metabolite/antifolate agent, methotrexate. Current cytotoxins have far greater potency and can be divided into three main groups: auristatins, maytansines and calicheamicins.

The development of site-specific conjugation methodologies for constructing homogeneous ADCs is an especially promising path to improving ADC design, which will open the way for novel cancer therapeutics.

References:

[1] Tsuchikama K, et al. Protein Cell. 2016 Oct 14. DOI:10.1007/s13238-016-0323-0.

[2] Peters C, et al. Biosci Rep. 2015 Jun 12;35(4). pii: e00225. doi: 10.1042/BSR20150089.

Targets for  Signaling Pathways

Products for  Signaling Pathways

  1. Cat.No. Product Name Information
  2. GC49823 2′-C-β-Methylguanosine An active nucleoside metabolite of BMS-986094 2′-C-β-Methylguanosine  Chemical Structure
  3. GC67384 2′-Deoxy-β-L-uridine 2'-Deoxy-β-L-uridine is a nucledside analogue and a specific substrate for the viral enzyme, shows no stereospecificity against herpes simplex 1 (HSV1) thymidine kinase (TK). 2′-Deoxy-β-L-uridine exerts antiviral activity via the interation of 5'-triphosphates with the viral DNA polymerase. 2′-Deoxy-β-L-uridine  Chemical Structure
  4. GC61667 2′-Deoxy-2′-fluoroadenosine 2′-Deoxy-2′-fluoroadenosine can be used for thesynthesisof 2′-Deoxy-2′-fluoro-modified oligonucleotides hybridized with RNA. 2′-Deoxy-2′-fluoroadenosine can be cleaved efficiently by E. coli purine nucleoside phosphorylase (PNP) to the toxic agent 2-fluoroadenine (FAde). 2′-Deoxy-2′-fluoroadenosine shows excellent in vivo activity against tumors expressing E. coli PNP. 2′-Deoxy-2′-fluoroadenosine  Chemical Structure
  5. GC61931 2′-Deoxy-2′-fluoroguanosine 2′-Deoxy-2′-fluoroguanosine, a nucleoside analog, is a potent inhibitor of influenza virus strains, with an EC90 of <0.35 μM for influenza virus A and B strains. 2′-Deoxy-2′-fluoroguanosine  Chemical Structure
  6. GC64738 2′-Deoxyadenosine 5′-monophosphate disodium 2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate disodium  Chemical Structure
  7. GC49514 2′-Deoxyuridine-d2 An internal standard for the quantification of 2’-deoxyuridine 2′-Deoxyuridine-d2  Chemical Structure
  8. GC61936 2′-O-(2-Methoxyethyl)adenosine 2′-O-(2-Methoxyethyl)adenosine is a compound can be used in the synthesis of oligonucleotides. 2′-O-(2-Methoxyethyl)adenosine  Chemical Structure
  9. GC48873 2′-O-Methylcytidine An inhibitor of HCV NS5B 2′-O-Methylcytidine  Chemical Structure
  10. GC61699 2′-O-Methyluridine 2'-O-methyluridine is found in rRNA, snRNA, snoRNA and tRNA of Archaea, Bacteria, and Eukaryota. 2′-O-Methyluridine  Chemical Structure
  11. GC64389 2’-Deoxy-5-formylcytidine 2’-Deoxy-5-formylcytidine is an effective internal triplet photosensitizer in DNA. 2’-Deoxy-5-formylcytidine  Chemical Structure
  12. GC52122 2’-Deoxyadenosine-5’-diphosphate (sodium salt) A nucleotide diphosphate 2’-Deoxyadenosine-5’-diphosphate (sodium salt)  Chemical Structure
  13. GC62772 2’-Deoxyadenosine-5’-triphosphate trisodium 2’-Deoxyadenosine-5’-triphosphate trisodium (dATP trisodium) is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase. 2’-Deoxyadenosine-5’-triphosphate trisodium  Chemical Structure
  14. GC62774 2’-Deoxyguanosine 5’-monophosphate disodium 2’-Deoxyguanosine 5’-monophosphate disodium (5′-dGMP disodium) is a mononucleotide having guanine as the nucleobase. 2’-Deoxyguanosine 5’-monophosphate disodium  Chemical Structure
  15. GC64400 2’-Hydroxy-5’-methylacetophenone 2’-Hydroxy-5’-methylacetophenone belongs to the class of organic compounds known as alkyl-phenylketones. 2’-Hydroxy-5’-methylacetophenone  Chemical Structure
  16. GC62530 2’-O-Me-C(Bz) Phosphoramidite 2’-O-Me-C(Bz) Phosphoramidite is a modified phosphoramidite monomer, which can be used for the oligonucleotide synthesis. 2’-O-Me-C(Bz) Phosphoramidite  Chemical Structure
  17. GC62529 2’-OMe-A(Bz) Phosphoramidite 2’-OMe-A(Bz) Phosphoramidite is a modified phosphoramidite monomer, which can be used for the oligonucleotide synthesis. 2’-OMe-A(Bz) Phosphoramidite  Chemical Structure
  18. GC62531 2’-OMe-G(ibu) Phosphoramidite 2’-OMe-G(ibu) Phosphoramidite is a modified phosphoramidite monomer, which can be used for the oligonucleotide synthesis. 2’-OMe-G(ibu) Phosphoramidite  Chemical Structure
  19. GC61756 2'-Deoxy-2'-fluorocytidine 2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2'-Deoxy-2'-fluorocytidine  Chemical Structure
  20. GC61824 2'-Deoxy-2'-fluorouridine 2'-Deoxy-2'-fluorouridine can be used as an intermediate for antiinfluenza virus agents synthesis. 2'-Deoxy-2'-fluorouridine  Chemical Structure
  21. GC61929 2'-O-(2-Methoxyethyl)-cytidine 2'-O-(2-Methoxyethyl)-cytidine is a synthetic oligonucleotide conversed from uridine. 2'-O-(2-Methoxyethyl)-uridine has the potential for chemotherapeutic agents development. 2'-O-(2-Methoxyethyl)-cytidine  Chemical Structure
  22. GC61671 2'-O-(2-Methoxyethyl)-uridine 2'-O-(2-Methoxyethyl)-uridine is a synthetic oligonucleotide conversed from uridine. 2'-O-(2-Methoxyethyl)-uridine has the potential for chemotherapeutic agents development. 2'-O-(2-Methoxyethyl)-uridine  Chemical Structure
  23. GC61922 2'-OMe-Ac-C Phosphoramidite 2'-OMe-Ac-C Phosphoramidite is a modified phosphoramidite and can be used for the oligonucleotide synthesis. 2'-OMe-Ac-C Phosphoramidite  Chemical Structure
  24. GC62764 2,2′-Dipyridyl disulfide 2,2′-Dipyridyl disulfide  Chemical Structure
  25. GC61754 2,2'-Bipyridine 2,2'-Bipyridine is the unique molecular scaffold of the bioactive natural products. 2,2'-Bipyridine  Chemical Structure
  26. GC66487 2,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide 2,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. 2,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide  Chemical Structure
  27. GC12258 2,3-DCPE hydrochloride 2,3-DCPE hydrochloride  Chemical Structure
  28. GC67743 2,3-Dihydroxyquinoxaline 2,3-Dihydroxyquinoxaline  Chemical Structure
  29. GC61921 2,3-Dimethyl-2,3-diphenylbutane 2,3-Dimethyl-2,3-diphenylbutane is one of the decomposition of Dicumylperoxide (DCP). 2,3-Dimethyl-2,3-diphenylbutane  Chemical Structure
  30. GC49671 2,3-Oxidosqualene An intermediate in the biosynthesis of sterols 2,3-Oxidosqualene  Chemical Structure
  31. GC61923 2,3-Pentanedione 2,3-Pentanedione is a common constituent of synthetic flavorings and is used to impart a butter, strawberry, caramel, fruit, rum, or cheese flavor in beverages, ice cream, candy, baked goods, gelatins, and puddings. 2,3-Pentanedione  Chemical Structure
  32. GC25006 2,4'-Dihydroxybenzophenone 2,4'-Dihydroxybenzophenone (DHBP) is an organic compound used for the synthesis of pharmaceutical agents. 2,4'-Dihydroxybenzophenone  Chemical Structure
  33. GC68044 2,4,6-Trihydroxybenzaldehyde 2,4,6-Trihydroxybenzaldehyde  Chemical Structure
  34. GC64399 2,4,6-Trihydroxybenzoic acid 2,4,6-Trihydroxybenzoic acid, the flavonoid metabolite, is a CDK inhibitor. 2,4,6-Trihydroxybenzoic acid can be used for the research of cancer. 2,4,6-Trihydroxybenzoic acid  Chemical Structure
  35. GC68452 2,4,6-Triiodophenol 2,4,6-Triiodophenol  Chemical Structure
  36. GC68234 2,4-Difluorobenzaldehyde 2,4-Difluorobenzaldehyde  Chemical Structure
  37. GC61836 2,4-Difluororesorcinol 2,4-Difluororesorcinol is a fluorinated building block. 2,4-Difluororesorcinol  Chemical Structure
  38. GC61702 2,4-Dimethoxybenzyl alcohol 2,4-Dimethoxybenzyl alcohol, an aromatic alcohol, is a substrate of glucose-methanol-choline (GMC) oxidoreductase. 2,4-Dimethoxybenzyl alcohol  Chemical Structure
  39. GC61656 2,6,6-Trimethylbicyclo[3.1.1]heptan-3-ol 2,6,6-Trimethylbicyclo[3.1.1]heptan-3-ol is isolated from Chrysanthemum indicum L. 2,6,6-Trimethylbicyclo[3.1.1]heptan-3-ol  Chemical Structure
  40. GC62233 2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide GDC-046 is a potent, selective, and orally bioavailable TYK2 inhibitor with Kis of 4.8, 0.7, 0.7, and 0.4 nM for TYK2, JAK1, JAK2, and JAK3, respectively. 2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide  Chemical Structure
  41. GC68132 2,6-Dichloroquinone-4-chloroimide 2,6-Dichloroquinone-4-chloroimide  Chemical Structure
  42. GC64627 2,6-Dimethoxy-1,4-benzoquinone 2,6-Dimethoxy-1,4-benzoquinone  Chemical Structure
  43. GC64411 2,6-Dimethoxyphenol 2,6-Dimethoxyphenol is a phenolic compound that is extensively used for the measurement of laccase activity. 2,6-Dimethoxyphenol  Chemical Structure
  44. GC66679 2,6-Dimethyl-L-tyrosine 2,6-Dimethyl-L-tyrosine (Dmt) is a tyrosine derivative that enhances receptor affinity, functional bioactivity and in vivo analgesia of opioid peptides. 2,6-Dimethyl-L-tyrosine  Chemical Structure
  45. GC19682 2,6-Dimethylpyrazine 2,6-Dimethylpyrazine is a key aroma compound in Boletus edulis. 2,6-Dimethylpyrazine  Chemical Structure
  46. GC62766 2,6-Dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid hydrate 2,6-Dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid hydrate is an endogenous metabolite. 2,6-Dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid hydrate  Chemical Structure
  47. GC68512 2,7-Dichlorodihydrofluorescein

    2,7-Dichlorodihydrofluorescein (DCFH2) is a non-fluorescent probe. 2,7-Dichlorodihydrofluorescein produces highly fluorescent 2',7'-dichlorofluorescein (DCF), which can be used for measuring reactive oxygen species.

    2,7-Dichlorodihydrofluorescein  Chemical Structure
  48. GC65461 2,8-Dihydroxyadenine 2,8-Dihydroxyadenine, an endogenous metabolite, can cause the formation of urinary crystals and kidney stones. 2,8-Dihydroxyadenine  Chemical Structure
  49. GC49159 2-(1-Piperazinyl)pyrimidine An α2-AR antagonist and active metabolite of azapirones 2-(1-Piperazinyl)pyrimidine  Chemical Structure
  50. GC62763 2-(2’,3’,4’-Trihydroxybutyl)quinoxaline 2-(2’,3’,4’-Trihydroxybutyl)quinoxaline is a food metabolite. 2-(2’,3’,4’-Trihydroxybutyl)quinoxaline  Chemical Structure
  51. GC66721 2-(2-(6-chlorohexyloxy)ethoxy)ethanamine hydrochloride 2-(2-(6-chlorohexyloxy)ethoxy)ethanamine (hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. 2-(2-(6-chlorohexyloxy)ethoxy)ethanamine hydrochloride  Chemical Structure
  52. GC49330 2-(2-Aminoethyl)-3-(4-chlorophenyl)-3-hydroxyisoindol-1-one (hydrochloride) A metabolite of mazindol 2-(2-Aminoethyl)-3-(4-chlorophenyl)-3-hydroxyisoindol-1-one (hydrochloride)  Chemical Structure
  53. GC68504 2-(2-Methylbenzamido)acetic acid-d7

    2-(2-Methylbenzamido)acetic acid-d7 is the deuterated form of 2-(2-Methylbenzamido)acetic acid. 2-(2-Methylbenzamido)acetic acid is a metabolite that can be detected in urine.

    2-(2-Methylbenzamido)acetic acid-d7  Chemical Structure
  54. GC19560 2-(2-Phenylethyl)chromone 2-(2-Phenylethyl)chromone (Flidersiachromone) is one of 2-(2-phenylethyl)chromones that can be found in Chinese eaglewood from Aquilaria sinensis. 2-(2-Phenylethyl)chromone  Chemical Structure
  55. GC66678 2-(3-Trifluoromethylphenyl)glycine hydrochloride 2-(3-Trifluoromethylphenyl)glycine hydrochloride is a precursor of substituted 2-acetamido-5-aryl-l, 2,4-triazolones. Substituted 2-acetamido-5-aryl-l, 2,4-triazolones are dual V1a/V2 receptor antagonists and can be used in cardiovascular disease research. 2-(3-Trifluoromethylphenyl)glycine hydrochloride  Chemical Structure
  56. GC67619 2-(4-Biphenylyl)-5-phenyl-1,3,4-oxadiazole 2-(4-Biphenylyl)-5-phenyl-1,3,4-oxadiazole is a laser dyes with high photoluminescence (PL) quantum efficiency. 2-(4-Biphenylyl)-5-phenyl-1,3,4-oxadiazole  Chemical Structure
  57. GC68093 2-(4-Chlorophenoxy)ethanol 2-(4-Chlorophenoxy)ethanol  Chemical Structure
  58. GC66595 2-(Azido-PEG2-amido)-1,3-propandiol 2-(Azido-PEG2-amido)-13-propandiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. 2-(Azido-PEG2-amido)-1,3-propandiol  Chemical Structure
  59. GC66746 2-(Azido-PEG3-amido)-1,3-bis(carboxylethoxy)propane 2-Azido-PEG3-amido-13-biscarboxylethoxypropane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. 2-(Azido-PEG3-amido)-1,3-bis(carboxylethoxy)propane  Chemical Structure
  60. GC66548 2-(Azido-PEG3-amido)-1,3-bis(NHS ester) 2-(Azido-PEG3-amido)-1,3-bis(NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. 2-(Azido-PEG3-amido)-1,3-bis(NHS ester)  Chemical Structure
  61. GC67303 2-(Biotin-amido)-1,3-bis-(C1-PEG1-acid) 2-(Biotin-amido)-13-bis(carboxylethoxy)propane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. 2-(Biotin-amido)-1,3-bis-(C1-PEG1-acid)  Chemical Structure
  62. GC52152 2-(N-Methylperfluorooctanesulfonamido)acetic Acid 2-(N-Methylperfluorooctanesulfonamido)acetic Acid  Chemical Structure
  63. GC66326 2-(Naphthalen-1-yl)-5-phenyloxazole 2-(Naphthalen-1-yl)-5-phenyloxazole (α-NPO) is an organic fluorescent dye. 2-(Naphthalen-1-yl)-5-phenyloxazole has a nitrogen atom in its structure that can interfere with the nitrogen content from the amination step. 2-(Naphthalen-1-yl)-5-phenyloxazole  Chemical Structure
  64. GC65414 2-(Tetradecylthio)acetic acid 2-Tetradecylthio acetic acid is a pan-peroxisome proliferator activated receptor (pan-PPAR) activator. 2-(Tetradecylthio)acetic acid  Chemical Structure
  65. GC25008 2-Acetamidofluorene 2-Acetamidofluorene  Chemical Structure
  66. GC19645 2-Acetylfuran 2-Acetylfuran (2-Furyl methyl ketone), an important flavour compound or intermediate in foods, is isolated from essential oils, sweet corn products, fruits and flowers. 2-Acetylfuran  Chemical Structure
  67. GC61710 2-Acetylpyrrole 2-Acetylpyrrole is a product of model browning systems, and has been isolated as a major flavour component of many foods. 2-Acetylpyrrole  Chemical Structure
  68. GC67087 2-Amino-1,3-bis(carboxylethoxy)propane 2-Amino-13-bis(carboxylethoxy)propane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. 2-Amino-1,3-bis(carboxylethoxy)propane  Chemical Structure
  69. GC64983 2-Amino-2'-deoxyadenosine 2-Amino-2'-deoxyadenosine is a deoxyribonucleoside used for the oligonucleotide synthesis. 2-Amino-2'-deoxyadenosine  Chemical Structure
  70. GC66717 2-Amino-2-(p-tolyl)acetic acid 2-Amino-2-(p-tolyl)acetic acid is used for optimizing azide skeleton, and is the intermediate in the synthesis of 1,3, 4-thiadiazole compounds. 1,3,4-thiadiazole compounds exhibit potential anti-cancer activity, and inhibit glutaminase (GLSI). 2-Amino-2-(p-tolyl)acetic acid  Chemical Structure
  71. GC62768 2-Amino-2-deoxyglucose hydrochloride 2-Amino-2-deoxyglucose hydrochloride is a hexosamine hydrochloride can be used in the synthesis of cyclopropene-modified hexosamine derivative Ac4GlcNCyoc and Ac4GalNCyoc. 2-Amino-2-deoxyglucose hydrochloride  Chemical Structure
  72. GC49362 2-Amino-3,8-dimethylimidazo-[4,5-f]-quinoxaline A food-derived carcinogen 2-Amino-3,8-dimethylimidazo-[4,5-f]-quinoxaline  Chemical Structure
  73. GC62769 2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid 2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid is an endogenous metabolite. 2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid  Chemical Structure
  74. GC68195 2-Amino-5-methylthiophene-3-carbonitrile 2-Amino-5-methylthiophene-3-carbonitrile  Chemical Structure
  75. GC62770 2-Amino-5-ureidopentanoic acid 2-Amino-5-ureidopentanoic acid is an endogenous metabolite. 2-Amino-5-ureidopentanoic acid  Chemical Structure
  76. GC64803 2-Amino-8-oxononanoic acid hydrochloride 2-Amino-8-oxononanoic acid (hydrochloride) is the hydrochloride form of 2-Amino-8-oxononanoic acid. 2-Amino-8-oxononanoic acid hydrochloride  Chemical Structure
  77. GC52029 2-Aminoflubendazole 2-Aminoflubendazole  Chemical Structure
  78. GC61639 2-Aminoimidazole 2-Aminoimidazole is a potent antibiofilm agent that can be used as an adjuvant to antimicrobial. 2-Aminoimidazole  Chemical Structure
  79. GC64739 2-Aminoquinoline 2-Aminoquinoline (2-Quinolinamine) is a promising compound as bioavailable nNOS inhibitor but suffers from low human nNOS inhibition, low selectivity versus human eNOS, and significant binding to other CNS targets. 2-Aminoquinoline  Chemical Structure
  80. GC49481 2-Aminotetralin A neuromodulatory agent 2-Aminotetralin  Chemical Structure
  81. GN10065 2-Atractylenolide 2-Atractylenolide  Chemical Structure
  82. GC65868 2-Benzylbenzoic acid 2-Benzylbenzoic acid can be used for compound synthesis. 2-Benzylbenzoic acid  Chemical Structure
  83. GC49609 2-bromo 17β-Estradiol A synthetic steroid and inhibitor of estrogen 2-hydroxylase 2-bromo 17β-Estradiol  Chemical Structure
  84. GC66798 2-Bromo-2,2-dimethyl-acetamido-PEG3-acid 2-Bromo-22-dimethyl-acetamido-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. 2-Bromo-2,2-dimethyl-acetamido-PEG3-acid  Chemical Structure
  85. GC62771 2-Bromo-6-nitrophenol 2-Bromo-6-nitrophenol is converted via 2-bromo-6-aminophenol to N-acetyl-2-bromo-6-aminophenol. 2-Bromo-6-nitrophenol  Chemical Structure
  86. GC68160 2-Chloro-1,4-naphthoquinone 2-Chloro-1,4-naphthoquinone  Chemical Structure
  87. GC25009 2-Chloro-1-(4-fluorobenzyl)benzimidazole 2-Chloro-1-(4-fluorobenzyl)benzimidazole is an aldose reductase (ALR2) inhibitor which is used for preparation of disubstituted benzimidazole derivative. 2-Chloro-1-(4-fluorobenzyl)benzimidazole  Chemical Structure
  88. GC49272 2-Chloro-4-nitrophenyl α-D-maltotrioside A colorimetric α-amylase substrate 2-Chloro-4-nitrophenyl α-D-maltotrioside  Chemical Structure
  89. GC52141 2-Chloro-N-methyl-N-(4-nitrophenyl)acetamide 2-Chloro-N-methyl-N-(4-nitrophenyl)acetamide  Chemical Structure
  90. GC66257 2-Chloro-N6-furfuryladenine 2-Chloro-N6-furfuryladenine is a Kinetin riboside derivative. 2-Chloro-N6-furfuryladenine  Chemical Structure
  91. GC49718 2-Chloroadenosine 5-triphosphate (sodium salt) An adenine nucleotide and ATP analog 2-Chloroadenosine 5-triphosphate (sodium salt)  Chemical Structure
  92. GC48943 2-deoxy-2-fluoro-D-Glucose A glucose derivative with anticancer activity 2-deoxy-2-fluoro-D-Glucose  Chemical Structure
  93. GC62773 2-Deoxy-D-glucose 6-phosphate disodium 2-Deoxy-D-glucose 6-phosphate disodium, a derivative of 2-Deoxy-D-glucose, is produced in mammalian cells by the action of hexokinase on 2-DG. 2-Deoxy-D-glucose 6-phosphate disodium  Chemical Structure
  94. GC49223 2-deoxy-D-Glucose-13C6 An internal standard for the quantification of 2-deoxy-D-glucose 2-deoxy-D-Glucose-13C6  Chemical Structure
  95. GC68513 2-Deoxy-D-glucose-d

    2-Deoxy-D-glucose-d is the deuterated form of 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analogue and a glycolysis inhibitor that works by inhibiting hexokinase, an enzyme involved in glucose metabolism.

    2-Deoxy-D-glucose-d  Chemical Structure
  96. GC65021 2-Deoxyribose 5-phosphate disodium 2-Deoxyribose 5-phosphate disodium is a substrate of 2-deoxyribose-5-phosphate aldolase (DERA). 2-Deoxyribose 5-phosphate disodium  Chemical Structure
  97. GC61672 2-Ethyl-6-methylphenol 2-Ethyl-6-methylphenol, an alkylphenol, is isolated form the tumorigenic neutral subfraction of cigarette smoke condensate. 2-Ethyl-6-methylphenol  Chemical Structure
  98. GC61901 2-Heptanol 2-Heptanol is one of chemical constituents identified in the essential oil of rhizome of Curcuma angustifolia and Curcuma zedoaria. 2-Heptanol  Chemical Structure
  99. GC64054 2-Hexyldecanoic acid 2-hexyldecanoic acid can be used as an amidating agent . 2-Hexyldecanoic acid  Chemical Structure
  100. GC49172 2-hydroxy Estrone An active metabolite of estrone 2-hydroxy Estrone  Chemical Structure
  101. GC66412 2-Hydroxy-1-methoxyanthraquinone 2-Hydroxy-1-methoxyanthraquinone could be isolated from the stem bark of Morinda lucida Benth. (Rubiaceae) and possesses antibacterial activity. 2-Hydroxy-1-methoxyanthraquinone  Chemical Structure

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