Membrane Transporter/Ion Channel
Research Areas
- AMPAR(55)
- Aquaporins(3)
- Piezo Channels(6)
- ATPase(79)
- Calcium Channel(358)
- Cannabinoid Transporters(6)
- CFTR(51)
- Chloride Channels(12)
- GABA Receptor(203)
- Glucose Transporters(18)
- Glutamate (EAAT) Transporters(18)
- Glycine Receptors(2)
- GlyT(20)
- GTPase(31)
- ICB(1)
- MCT2(2)
- Monoamine transporter(17)
- Monocarboxylate Transporters(14)
- Multidrug Transporters(4)
- Na+/Ca2+ Exchanger(16)
- NKCC(9)
- NMDA Receptor(77)
- Nucleoside Transporters(6)
- Pannexin-1(2)
- P2X purinergic receptor(71)
- P-gp(10)
- Proton Pump(59)
- Potassium Channel(336)
- Sodium Channel(229)
- TRP Channel(190)
- TRPV1(10)
- URAT1(14)
- Other Channel Modulators(10)
- MCT(3)
- Kainate Receptors(11)
- Ionophore(3)
- sodium-hydrogen exchanger(3)
- Chloride Channel(33)
- CRAC Channel(14)
- EAAT2(6)
- HCN Channel(10)
- Na+/HCO3- Cotransporter(1)
- Na+/K+ ATPase(31)
- P-glycoprotein(60)
- iGluR(183)
- nAChR(127)
- VDAC(3)
- GlyR(1)
- Ferroportin(4)
- Urea Transporter(1)
- Na+/H+ Exchanger (NHE)(3)
- NTPDase(4)
- EAAT(7)
- ASCT(6)
- Apical Sodium-Dependent Bile Acid Transporter(1)
- Sec61(2)
- ATP-binding cassette (ABC) transporters(5)
- SLC39 (Zinc Transporter)(2)
- Sodium Phosphate Cotransporter(1)
Products Related to Membrane Transporter/Ion Channel(2456)
- GN10445(±)-Praeruptorin ACAS: 73069-25-7Purity: >98.00%
(±)-Praeruptorin A (PA) is the di-esterified product of ciskhellactone (CKL) and the major active ingredient in Peucedani Radix and exhibits dramatically anti-hypertensive effect typically through acting as a calcium channel blocker.
- GN10792Caffeic acidCAS: 331-39-5Purity: >98.50%
Caffeic acid is a hydroxycinnamic acid polyphenol compound with antioxidant activity. Caffeic acid is an inhibitor of TRPV1 ion channel and 5-lipoxygenase.
- GN1079920(S)-Ginsenoside Rg3CAS: 14197-60-5Purity: >98.00%
20(S)-Ginsenoside Rg3 is a rare ginsenoside extracted from ginseng (Na + : IC 50 = 32.2±4.5μM; hKv1.4: IC 50 = 32.6±2.2μM).
- GC11120Ciclopirox ethanolamineCAS: 41621-49-2Purity: >99.50%
Ciclopirox ethanolamine (Ciclopirox ethanolamine) is a synthetic antifungal agent that can be used for superficial mycoses reseaech.
- GC14421CFTRinh-172CAS: 307510-92-5Purity: >98.50%
CFTRinh-172 was identified as a potent and selective blocker of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl - channel. CFTRinh-172 inhibits Cl - current in wild-type, G551D, and G1349D CFTR with K i value of 0.5μM.
- GC16585Golgicide ACAS: 1139889-93-2Purity: >98.00%
Golgicide A is a highly specific and reversible cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factor (ArfGEF GBF1) inhibitor. By selectively targeting GBF1 and reducing the activation of Arf1, Golgicide A blocks intracellular vesicle transport and protein secretion.
- GC13430(-)-BlebbistatinCAS: 856925-71-8Purity: >99.00%
(-)-Blebbistatin is one of the configurations of the racemic mixture (±)-Blebbistatin (Cat. No. GC12341) and is the active form. (-)-Blebbistatin is a cell-permeable inhibitor of non-muscle myosin II ATPase, which effectively inhibits multiple striated muscle myosins as well as vertebrate non-muscle myosins with IC 50 values ranging from 0.5-5μM, and only slightly inhibits smooth muscle myosin (IC 50 =80μM) .
- GC17683Brefeldin ACAS: 20350-15-6Purity: >99.50%
Brefeldin A is a macrocyclic lactone compound derived from fungi with protein transport inhibitory activity.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GN10311 | N－Methylcytisine | 486-86-2 | >99.50% | |
| GN10365 | Bufalin | 465-21-4 | >99.50% | |
Bufalin is a Na + /K + -ATPase inhibitor (α1: K d = 42.5nM; α2: K d = 45nM; α3: K d = 40nM). | ||||
| GN10437 | Imperatorin | 482-44-0 | >98.00% | |
| GN10445 | (±)-Praeruptorin A | 73069-25-7 | >98.00% | |
(±)-Praeruptorin A (PA) is the di-esterified product of ciskhellactone (CKL) and the major active ingredient in Peucedani Radix and exhibits dramatically anti-hypertensive effect typically through acting as a calcium channel blocker. | ||||
| GN10446 | Tetrandrine | 518-34-3 | >99.50% | |
| GN10517 | Ginsenoside Rf | 52286-58-5 | >99.50% | |
| GN10549 | Ginsenoside Rd | 52705-93-8 | >98.00% | |
| GN10612 | (+)- Praeruptorin C | 72463-77-5 | >98.00% | |
| GN10715 | Catharanthine Tartrate | 4168-17-6 | >99.50% | |
| GN10747 | Lannaconitine | 32854-75-4 | >98.00% | |
| GN10779 | Reserpine | 50-55-5 | >98.50% | |
| GN10791 | Catharanthine | 2468-21-5 | >98.00% | |
| GN10792 | Caffeic acid | 331-39-5 | >98.50% | |
Caffeic acid is a hydroxycinnamic acid polyphenol compound with antioxidant activity. Caffeic acid is an inhibitor of TRPV1 ion channel and 5-lipoxygenase. | ||||
| GN10799 | 20(S)-Ginsenoside Rg3 | 14197-60-5 | >98.00% | |
20(S)-Ginsenoside Rg3 is a rare ginsenoside extracted from ginseng (Na + : IC 50 = 32.2±4.5μM; hKv1.4: IC 50 = 32.6±2.2μM). | ||||
| GN10805 | Protopanaxdiol | 30636-90-9 | >98.00% | |
| GN10809 | Tanshinone IIA sulfonate sodium | 69659-80-9 | >98.00% | |
| GN10812 | Acacetin | 480-44-4 | >99.50% | |
| GC11120 | Ciclopirox ethanolamine | 41621-49-2 | >99.50% | |
Ciclopirox ethanolamine (Ciclopirox ethanolamine) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. | ||||
| GC14421 | CFTRinh-172 | 307510-92-5 | >98.50% | |
CFTRinh-172 was identified as a potent and selective blocker of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl - channel. CFTRinh-172 inhibits Cl - current in wild-type, G551D, and G1349D CFTR with K i value of 0.5μM. | ||||
| GC16833 | BTB06584 | 219793-45-0 | >98.00% | |
F1F0 ATP synthases | ||||
| GC16585 | Golgicide A | 1139889-93-2 | >98.00% | |
Golgicide A is a highly specific and reversible cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factor (ArfGEF GBF1) inhibitor. By selectively targeting GBF1 and reducing the activation of Arf1, Golgicide A blocks intracellular vesicle transport and protein secretion. | ||||
| GC13430 | (-)-Blebbistatin | 856925-71-8 | >99.00% | |
(-)-Blebbistatin is one of the configurations of the racemic mixture (±)-Blebbistatin (Cat. No. GC12341) and is the active form. (-)-Blebbistatin is a cell-permeable inhibitor of non-muscle myosin II ATPase, which effectively inhibits multiple striated muscle myosins as well as vertebrate non-muscle myosins with IC 50 values ranging from 0.5-5μM, and only slightly inhibits smooth muscle myosin (IC 50 =80μM) . | ||||
| GC17683 | Brefeldin A | 20350-15-6 | >99.50% | |
Brefeldin A is a macrocyclic lactone compound derived from fungi with protein transport inhibitory activity. | ||||
| GC10590 | Lercanidipine hydrochloride | 132866-11-6 | >99.50% | |
calcium channel blocker | ||||