Membrane Transporter/Ion Channel
Research Areas
- AMPAR(55)
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- ATPase(79)
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- P-gp(10)
- Proton Pump(60)
- Potassium Channel(337)
- Sodium Channel(234)
- TRP Channel(193)
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- Other Channel Modulators(10)
- MCT(3)
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- Ionophore(3)
- sodium-hydrogen exchanger(3)
- Chloride Channel(34)
- CRAC Channel(14)
- EAAT2(6)
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- Na+/HCO3- Cotransporter(1)
- Na+/K+ ATPase(31)
- P-glycoprotein(61)
- iGluR(188)
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- VDAC(4)
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- Urea Transporter(1)
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- NTPDase(5)
- EAAT(7)
- ASCT(6)
- Apical Sodium-Dependent Bile Acid Transporter(1)
- Sec61(2)
- ATP-binding cassette (ABC) transporters(5)
- SLC39 (Zinc Transporter)(2)
- Sodium Phosphate Cotransporter(1)
Products Related to Membrane Transporter/Ion Channel(2486)
- GC14421CFTRinh-172CAS: 307510-92-5Purity: >98.50%
CFTRinh-172 was identified as a potent and selective blocker of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl - channel. CFTRinh-172 inhibits Cl - current in wild-type, G551D, and G1349D CFTR with K i value of 0.5μM.
- GC16585Golgicide ACAS: 1139889-93-2Purity: >98.00%
Golgicide A is a highly specific and reversible cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factor (ArfGEF GBF1) inhibitor. By selectively targeting GBF1 and reducing the activation of Arf1, Golgicide A blocks intracellular vesicle transport and protein secretion.
- GC13430(-)-BlebbistatinCAS: 856925-71-8Purity: >99.00%
(-)-Blebbistatin is one of the configurations of the racemic mixture (±)-Blebbistatin (Cat. No. GC12341) and is the active form. (-)-Blebbistatin is a cell-permeable inhibitor of non-muscle myosin II ATPase, which effectively inhibits multiple striated muscle myosins as well as vertebrate non-muscle myosins with IC 50 values ranging from 0.5-5μM, and only slightly inhibits smooth muscle myosin (IC 50 =80μM) .
- GC17683Brefeldin ACAS: 20350-15-6Purity: >99.50%
Brefeldin A is a macrocyclic lactone compound derived from fungi with protein transport inhibitory activity.
- GC174694-AminopyridineCAS: 504-24-5Purity: >98.00%
4-Aminopyridine is a non‑selective K⁺ channel blocker.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC14421 | CFTRinh-172 | 307510-92-5 | >98.50% | |
CFTRinh-172 was identified as a potent and selective blocker of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl - channel. CFTRinh-172 inhibits Cl - current in wild-type, G551D, and G1349D CFTR with K i value of 0.5μM. | ||||
| GC16833 | BTB06584 | 219793-45-0 | >98.00% | |
F1F0 ATP synthases | ||||
| GC16585 | Golgicide A | 1139889-93-2 | >98.00% | |
Golgicide A is a highly specific and reversible cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factor (ArfGEF GBF1) inhibitor. By selectively targeting GBF1 and reducing the activation of Arf1, Golgicide A blocks intracellular vesicle transport and protein secretion. | ||||
| GC13430 | (-)-Blebbistatin | 856925-71-8 | >99.00% | |
(-)-Blebbistatin is one of the configurations of the racemic mixture (±)-Blebbistatin (Cat. No. GC12341) and is the active form. (-)-Blebbistatin is a cell-permeable inhibitor of non-muscle myosin II ATPase, which effectively inhibits multiple striated muscle myosins as well as vertebrate non-muscle myosins with IC 50 values ranging from 0.5-5μM, and only slightly inhibits smooth muscle myosin (IC 50 =80μM) . | ||||
| GC17683 | Brefeldin A | 20350-15-6 | >99.50% | |
Brefeldin A is a macrocyclic lactone compound derived from fungi with protein transport inhibitory activity. | ||||
| GC10590 | Lercanidipine hydrochloride | 132866-11-6 | >99.50% | |
calcium channel blocker | ||||
| GC12718 | Pantoprazole | 102625-70-7 | >98.00% | |
H+/K+-ATPase inhibitor | ||||
| GC12769 | Nonivamide | 2444-46-4 | >98.00% | |
agonist of the VR1 (TRPV1) | ||||
| GC15670 | Rabeprazole sodium | 117976-90-6 | >98.00% | |
proton pump inhibitor | ||||
| GC16645 | Rabeprazole | 117976-89-3 | >98.00% | |
proton pump inhibitor | ||||
| GC17469 | 4-Aminopyridine | 504-24-5 | >98.00% | |
4-Aminopyridine is a non‑selective K⁺ channel blocker. | ||||
| GC17616 | PPQ-102 | 931706-15-9 | >99.50% | |
potent CFTR inhibitor | ||||
| GC17625 | Lercanidipine | 100427-26-7 | >98.00% | |
calcium channel blocker | ||||
| GC17691 | Phaclofen | 114012-12-3 | >98.00% | |
GABAB antagonist | ||||