Calcium Channel
Calcium channel is an ion channel that selectively permeable to calcium ions. It serves vital functions in cellular signal transduction.
Products for Calcium Channel
- Cat.No. Product Name Information
- GC10786 DHBP dibromide ryanodine receptor blocker
- GC43464 Diltiazem (hydrochloride) Diltiazem (hydrochloride) is an analytical reference standard that is functionally categorized as a calcium channel blocker.
- GC64299 Diltiazem-d3 hydrochloride
- GC63881 DL-Phenylalanine-d5 hydrochloride
- GC32652 Dopropidil Dopropidil is a novel anti-anginal calcium ion modulating agent, possessing intracellular calcium antagonist activity andanti-ischemic effects in several predictive animal models.
- GC43575 DS16570511 DS16570511 is an inhibitor of the mitochondrial calcium uniporter.
- GC32580 Efonidipine (NZ-105) Efonidipine (NZ-105)(NZ-105) is a dual T-type and L-type calcium channel blocker (CCB).
- GC32573 Efonidipine hydrochloride (NZ-105 hydrochloride) Efonidipine Hcl (NZ-105) is a dual T-type and L-type calcium channel blocker (CCB).
- GC35963 Efonidipine hydrochloride monoethanolate Efonidipine hydrochloride monoethanolate (NZ-105 hydrochloride monoethanolate) is a dual T-type and L-type calcium channel blocker (CCB).
- GC10519 Ethacrynic acid - d5 Used as an internal standard for GC- or LC-mass spectrometry
- GC33695 Ethosuximide An anticonvulsant
- GC33700 Etiracetam (UCB 6474) Etiracetam (UCB 6474) (UCB 6474) is an acetylcholine agonist and a nootropic drug of the racetam family.
- GC65248 Etripamil Etripamil (MSP-2017) is a short-acting L-type calcium-channel antagonist, can be used for the research of Paroxysmal Supraventricular Tachycardia (PSVT).
- GC19152 Fantofarone Fantofarone is a highly potent Calcium Channel antagonist.
- GC13869 Fasudil Calcium antagonist
- GC14289 Fasudil (HA-1077) HCl Fasudil (HA-1077; AT877) Hydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively. Fasudil (HA-1077) HCl is also a potent Ca2+ channel antagonist and vasodilator.
- GC17173 Felodipine Selective L-type Ca2+ channel blocker
- GC18086 Fendiline (hydrochloride) α2-adrenergic receptor antagonist
- GC18641 Ferutinin Ferutinin is a plant-derived ester of a sesquiterpenic alcohol that acts as an agonist for estrogen receptor (ER) α (IC50 = 33.1 nM) and an agonist/antagonist for ERβ (IC50 = 180.5 nM).
- GC47352 FK-506-13C-d2 An internal standard for the quantification of FK-506
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GC13466
Flufenamic acid
TRPC activator
- GC16532 Flunarizine 2HCl Flunarizine 2HCl is a potent dual Na+/Ca2+ channel (T-type) blocker.
- GC49739 Fluo-2 (potassium salt) A cell-impermeable fluorescent calcium indicator
- GC49458 Fluo-2 AM A cell-permeable fluorescent calcium indicator
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GC43681
Fluo-3 (ammonium salt)
Fluo-3 (ammonium salt) is a fluorescent calcium indicator commonly used in flow cytometry and cell-based experiments to detect changes in intracellular calcium levels.
- GC43682 Fluo-3 (potassium salt) Fluo-3 (potassium salt) is a fluorescent calcium indicator commonly used in flow cytometry and cell-based experiments to detect changes in intracellular calcium levels.
- GC43683 Fluo-3 (sodium salt) Fluo-3 is a fluorescent calcium indicator commonly used in flow cytometry and cell-based experiments to detect changes in intracellular calcium levels.
- GC43684 Fluo-3FF (potassium salt) Fluo-3FF is a fluorescent calcium indicator.
- GC49741 Fluo-4 (potassium salt) A cell-impermeable fluorescent calcium indicator
- GC11492 Fluspirilene potent, non-competitive antagonist of agonist-activated L-type calcium channels
- GC10506 FPL 64176 L-type Ca2+ channels activator
- GC43711 Fura-2 (potassium salt) Fura-2 (potassium salt) is a scaled fluorescent dye that can be used for intracellular calcium imaging with the Kd value of 140 nM.
- GC43712 Fura-2 (sodium salt) Fura-2 is a ratiometric fluorescent calcium indicator that can be used to detect calcium in cells.
- GC49462 Fura-2 Leakage Resistant (potassium salt) A cell-impermeable, ratiometric fluorescent calcium indicator
- GC49465 Fura-2 Leakage Resistant AM A cell-permeable, ratiometric fluorescent calcium indicator
- GC43713 Fura-FF (potassium salt) Fura-FF (potassium salt) is a low-affinity fluorescent dye for calcium (Ex/Em: 365/514 nm in the absence of calcium; 339/507 nm in the presence of a high calcium concentration).
- GC43714 Fura-FF AM Fura-FF AM is a cell-permeable acetoxymethyl ester of the fluorescence calcium indicator fura-FF (potassium salt).
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GC12714
Gabapentin
GABA enhancer
- GC36097 Gabapentin enacarbil Gabapentin enacarbil (XP-13512) is a prodrug for the anticonvulsant and analgesic drug gabapentin.
- GC17316 Gabapentin HCl Gabapentin HCl is a potent, orally active P/Q type Ca2+ channel blocker.
- GC14771 Gadolinium chloride Calcium-sensing receptor (CaSR) agonist
- GC36105 Gallopamil Gallopamil (Methoxyverapamil), a methoxy derivative of Verapamil, is a phenylalkylamine calcium antagonist.
- GC43730 Ganglioside GM1 Asialo Mixture Ganglioside GM1 asialo is a component of cellular lipid rafts and can be formed by the cleavage of the sialic acid residue from ganglioside GM1 by neuraminidase.
- GN10549 Ginsenoside Rd
- GN10517 Ginsenoside Rf
- GN10069 Ginsenoside Ro
- GC41486 Glaucine Glaucine is an alkaloid originally isolated from G.
- GC36178 Gomisin J A lignan with diverse biological activities
- GC31683 GSK-7975A GSK-7975A is a potent and orally available CRAC channel inhibitor.
- GC30850 GV-58 GV-58 is a novel N- and P/Q-type calcium (Ca2+) channel agonist with EC50s of 7.21 and 8.81 μM, respectively.
- GA10299 H-Phe-OH
- GC38546 Heteroclitin D Heteroclitin D is a lignin from Kadsura medicinal plants with anti-liqid peroxidation.
- GC18027 Huwentoxin XVI N-type Ca2+ channel blocker,potent and selective
- GC49250 Hydroxydehydro Nifedipine Carboxylate A metabolite of nifedipine
- GC43884 Hyperforin (dicyclohexylammonium salt) Hyperforin is a natural activator of the steroid X receptor (active at 0.1 to 0.5 μg/ml) and inhibitor of several cytochrome P450 (CYP) isoforms (IC50 = 10 μg/ml for CYP2D6).
- GC15860 Ibutilide Fumarate Class III antiarrhythmic agent
- GC52466 ICR-1 (potassium salt) A cell-impermeable fluorescent calcium indicator
- GC52465 ICR-1 AM A cell-permeable fluorescent calcium indicator
- GC32537 Iganidipine Iganidipine is a Ca2+ antagonist.
- GC43899 Indo-1 (potassium salt) Indo-1 is a ratiometric fluorescent calcium indicator.
- GC43900 Indo-1 (sodium salt) Indo-1 is a ratiometric fluorescent calcium indicator.
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GC15148
Ionomycin calcium salt
Lonomycin is a selective calcium ionophore derived from S. conglobatus that mobilizes intracellular calcium stores.
- GC15446 Ionomycin free acid Ionomycin free acid (SQ23377) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus.
- GC39806 Isotachysterol 3 Isotachysterol 3 is an analog of 1,25-dihydrox Vitamin D3.
- GC10447 Isradipine (Dynacirc) Isradipine (Dynacirc) (PN 200-110) is an orally active L-type calcium channel blocker.
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GC50064
JTV 519 fumarate
Ryanodine receptor (RyR) inhibitor
- GC36371 JTV-519 free base JTV-519 free base (K201 free base) is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle.
- GC64004 JTV-519 hemifumarate JTV-519 hemifumarate (K201 hemifumarate) is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle.
- GC14656 L-651,582 L-651,582 (L-651582) is a cytostatic inhibitor of nonvoltage-operated calcium channels and calcium channel-mediated signaling pathways.
- GC44081 L-myo-Inositol-1,4,5-triphosphate (sodium salt) Ins(1,4,5)P3 is an isomer of the biologically important D-myo-inositol-1,4,5-triphosphate.
- GC64148 L-Phenylalanine-15N
- GC65050 L-Phenylalanine-d2
- GC63982 L-Phenylalanine-d5
- GC64290 L-Phenylalanine-d8
- GC15550 Lacidipine L-type calcium channel blocker
- GC25558 Lanthanum(III) chloride heptahydrate Lanthanum(III) chloride is the inorganic compound used in biochemical research to block the activity of divalent cation channels, mainly calcium channels.
- GC32533 Lemildipine (NB-818) Lemildipine (NB-818) is a new dihydropyridine calcium entry blocker.
- GC17625 Lercanidipine calcium channel blocker
- GC10590 Lercanidipine hydrochloride calcium channel blocker
- GC34912 Levamlodipine besylate Levamlodipine besylate ((S)-Amlodipine besylate) is a powerful dihydropyridine calcium channel blocker, possessing vasodilation properties and used in the treatment of hypertension and angina.
- GC38537 Lidoflazine Lidoflazine is a high affinity blocker of the HERG (human ether-a-go-go-related gene) K+ channel.
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GC44069
Linoleic Acid Amide
Linoleic acid amide is a primary fatty acid amide derived from linoleic acid.
- GC13997 Lomerizine HCl Lomerizine HCl is an antagonist of L- and T-type voltagegated calcium channels.
- GC17587 Manidipine Calcium channel blocker
- GC15293 Manidipine 2HCl Manidipine 2HCl (CV-4093) is a dihydropyridine compound and a calcium channel blocker for Ca2+ current with IC50 of 2.6 nM.
- GC32636 McN5691 (RWJ26240) McN5691 (RWJ26240) is a voltage-sensitive calcium channel blocker.
- GC17442 Methsuximide anticonvulsant medication
- GC39275 Methyl homoveratrate Methyl homoveratrate, a metabolite of RWJ-26240 in vivo, can be identified in plasma, urine and faecal extract.
- GC12268 Mibefradil A general calcium channel blocker
- GC10218 Mibefradil dihydrochloride A general calcium channel blocker
- GC30873 Mirogabalin (DS5565) Mirogabalin (DS5565) (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium channel complexes in the CNS.
- GC30961 Mirogabalin besylate (DS 5565 besylate) Mirogabalin besylate (DS 5565 besylate) is a selective and orally available ligand for the α2δ subunit of voltage-gated calcium channels, with Kds of 13.5 nM, 22.7 nM, 27 nM, and 47.6 nM for human α2δ-1, human α2δ-2, rat α2δ-1, and rat α2δ-2, respectively.
- GC19252 MK-8998 MK-8998 (MK-8998; compound 33) is a potent and selective inhibitor of the T-type calcium channel.
- GC15386 ML 218 hydrochloride ML 218 hydrochloride is a potent, selective and orally active T-type Ca2+ channels (Cav3.1, Cav3.2, Cav3.3) inhibitor with IC50s of 310 nM and 270 nM for Cav3.2 and Cav3.3, respectively.
- GC49440 ML-9 A PKB/Akt inhibitor
- GC11683 MRS 1845 store-operated Ca2+ channels blocker
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GC31200
Myomodulin
Myomodulin is a neuropeptide present in molluscs, insects, and gastropods.
- GC31178 N-type calcium channel blocker-1 N-type calcium channel blocker-1 is an orally active compound which shows high affinity to functionally block N-type calcium channels with an IC50 of 0.7 μM in the IMR32 assay.
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GC44290
NAADP (sodium salt)
Nicotinic acid adenine dinucleotide phosphate (NAADP) is a secondary messenger that induces calcium mobilization.
- GC10926 NAADP tetrasodium salt Ca2+ mobilizing agent