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Home >> Signaling Pathways >> Others >> Gutathione S-transferase

Gutathione S-transferase

GSTs (Glutathione s-transferases)is a detoxification enzyme that catalyze the binding of electrophilic substrates to glutathione. They involved in removal of ROS, inhibition of Jun kinase and can conjugate non-catalytically to various ligands.

Products for  Gutathione S-transferase

  1. Cat.No. Product Name Information
  2. GC64919 AZD9898 AZD9898 is an orally active leukotriene-C4 synthetase (LTC4S, glutathione S-transferase II) inhibitor, with an IC50 of 0.28 nM. AZD9898 Chemical Structure
  3. GC35727 Coniferyl ferulate

    A monolignal conjugate with diverse biological activities

     Coniferyl ferulate Chemical Structure
  4. GC35759 Curzerene Curzerene is a sesquiterpene is isolated from the rhizome of Curculigo orchioides Gaertn with anti-cancer activity. Curzerene inhibits glutathione S-transferase A1 (GSTA1) mRNA and protein expression. Curzerene induces cell apoptosis. Curzerene Chemical Structure
  5. GC10519 Ethacrynic acid - d5 Used as an internal standard for GC- or LC-mass spectrometry Ethacrynic acid - d5 Chemical Structure
  6. GC13409 Ezatiostat hydrochloride GST inhibitor Ezatiostat hydrochloride Chemical Structure
  7. GC33342 GSTO-IN-2 GSTO-IN-2 is a glutathione S-transferase inhibitor with IC50s of 3.6, 16.3, and 1.4 μM for GSTA2, GSTM1, and GSTP1-1. GSTO-IN-2 Chemical Structure
  8. GC32971 GSTO1-IN-1 GSTO1-IN-1 is a potent glutathione S-transferase omega 1 (GSTO1) inhibitor with an IC50 of 31 nM. GSTO1-IN-1 Chemical Structure
  9. GC17287 Iberin

    NSC 321801

     induces the expression of phase II detoxification enzymes, including quinone reductase and glutathione S-transferase Iberin Chemical Structure
  10. GC63518 LAS17 LAS17 is a potent and selective tyrosine-directed irreversible inhibitor for glutathione?S-Transferase Pi (GSTP1) . LAS17 inhibits GSTP1 activity with an IC50 of 0.5 ?M. LAS17 Chemical Structure
  11. GC44882 Seneciphylline

    NSC 30622

     Seneciphylline is an alkaloid that has been found F. Seneciphylline Chemical Structure
  12. GC65438 TK05 TK05 is a potent and selective inhibitor of leukotriene C4 synthase (LTC4S) with an IC50 of 95 nM. TK05 Chemical Structure
  13. GC30647 TLK117 (TER117)

    TER117

     TLK117 (TER117), the active metabolite of TLK199, selective inhibits Glutathione S-transferase P1-1 (GSTP1-1) with a Ki of 0.4 μM for GSTP. TLK117 (TER117) Chemical Structure

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