- Cat.No. Nombre del producto Información
- GC38036 PIN1 inhibitor API-1 El inhibidor de PIN1 API-1 es un inhibidor especÍfico de Pin1 (peptidil-prolil cis-trans isomerasa NIMA-interacting 1) (API-1) con una IC50 de 72,3 nM. El inhibidor de PIN1 API-1 se une directa y especÍficamente al dominio Pin1 peptidil-prolil isomerasa (PPIasa) e inhibe potentemente la actividad isomerizante cis-trans de Pin1. El inhibidor de PIN1 API-1 retiene la conformaciÓn activa de pXPO5 y restaura la capacidad de pXPO5 para transportar pre-miARN desde el nÚcleo al citoplasma, regulando asÍ la biogénesis de miARN contra el cÁncer para suprimir el desarrollo de carcinoma hepatocelular tanto in vitro como in vivo.
- GA22331 Hepcidin-25 (human) Hepcidin-25 (hepatic bactericidal protein), also referred to as LEAP-1 (liver-expressed antimicrobial peptide) has been independently discovered by two groups in human blood ultrafiltrate and urine. The peptide which is predominantly expressed in the liver, belongs to a new vertebrate family of small antimicrobial peptides that contain 8 cysteine residues and show significant antibacterial and antifungal activity. Further investigations revealed that hepicidin is the principal iron-regulatory hormone in humans. Hepcidin acts by binding to the iron exporter ferroportin, inducing its internalization and degradation, thereby blocking cellular iron efflux. Nemeth et al. demonstrated that the N-terminal part of the peptide hormone is essential for its activity. Former CAS-number 342790-21-0.
- GF04824 perampanel 3/4 hydrate
- GC42443 4-Methylumbelliferyl 6-thio-Palmitate-β-D-Glucopyranoside A fluorogenic substrate of PPT/CLN1
- GC43892 Ikarugamycin La ikarugamicina es un antibiÓtico y un inhibidor de la endocitosis mediada por clatrina (EMC).
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GC41184
1P-LSD (solution)
1P-LSD (solution) is an analytical reference material categorized as a lysergamide.
- GC46049 1cP-LSD (solution) An Analytical Reference Material
- GC26342 Triflusulfuron-methyl
- GC26341 Cupric hydroxide, AR
- GC26340 2-(2-Chloro-4-(methylsulfonyl)-3-((2,2,2-trifluoroethoxy)methyl)benzoyl)cyclohexane-1,3-dione
- GC26339 Mesosulfuron-Methyl
- GC30025 Dihydroethidium (Hydroethidine) Dihydroethdium(Hydroethidine) (DHE) oxidation is commonly used as a method for monitoring cellular production of "reactive oxygen species (ROS)".
- GC26338 α-Cypermethrin
- GC40775 Dexamethasone Dexamethasone, as one member of the glucocorticoid family, can protect against arthritis-related changes in cartilage structure and function, including matrix loss, inflammation and cartilage viability.
- GC15948 Prostaglandin E2 Prostaglandin E2 is a major metabolite produced from arachidonic acid catalyzed by Cyclooxygenase (COX).
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GC10839
Tubastatin A
A potent HDAC6 inhibitor
- GF28637 4-(4-Hydroxyphenyl)butanoic acid
- GC11421 L-364,373 KV7.1 (KCNQ1) channel activator
- GC36980 Propranolol Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively.
- GC30231 Fluo-4 AM A fluorescent calcium indicator
- GK10009 BCA Protein Assay Kit BCA Protein Assay Kit is a ready-to-use total protein content determination kit with a detection range of 20-2000μg/mL.
- GC63213 TDI-10229 TDI-10229 es un inhibidor potente y biodisponible por vÍa oral de la adenilil ciclasa soluble (sAC, ADCY10).
- GC26337 REHMANNIAE RADIX PRAEPARATA
- GC17476 MRS 2500 tetraammonium salt Highly potent and selective antagonist of the platelet P2Y1 receptor
- GC15332 Ticagrelor P2Y12 receptor antagonist
- GC41578 cis-10-Heptadecenoic Acid A monounsaturated fatty acid
- GC67352 (tert-Butoxycarbonyl)-D-cysteine La (terc-butoxicarbonil)-D-cisteína es un derivado de la cisteína.
- GC36881 PF-04937319 PF-04937319 es un activador de la glucoquinasa (GKA) con un valor de EC50 de 154,4 μM, una de las estrategias mÁs prometedoras para el tratamiento de la diabetes mellitus tipo 2.
- GC60064 AZD1656 AZD1656 es un activador de glucocinasa potente, selectivo y activo por vÍa oral con una EC50 de 60 nM.
- GC18280 13(E)-Docosenoic Acid A 22-carbon monounsaturated fatty acid
- GC49723 SenTraGor™ Cell Senescence Reagent A cellular senescence detection reagent
- GK10027 Bradford Protein Quantification Kit (Ready to use) The Bradford Protein Quantification Kit is a kit for rapid determination of protein concentrations in the range of 0.025-2mg/ml.
- GB53529 2-(2-(2-Methoxyethoxy)ethoxy)ethyl acrylate
- GC36816 Ornidazole Levo- Ornidazol Levo- es el isómero levo de Ornidazol.
- GC49141 Triacontanoic Acid A very long-chain saturated fatty acid
- GC19881 Golgi-Tracker Red Golgi red fluorescent probe, one of the sphingolipid fluorescent probes, which can be used for Golgi-specific fluorescent staining of living cells.
- GC15137 RS 56812 hydrochloride 5-HT3 partial agonist
- GC16162 ICI 162,846 histamine H2 receptor antagonist
- GC50009 LY 294002 hydrochloride Prototypical PI 3-kinase inhibitor; also inhibits other kinases
- GK10001 Cell Counting Kit-8 (CCK-8) Cell Counting Kit-8 (CCK-8) is a ready-to-use one-bottle solution which offers a simple, rapid, reliable and sensitive measurement of cell viability and cytotoxicity of various chemicals.
- GC61473 Trastuzumab deruxtecan An HER2 antibody-drug conjugate (ADC)
- GC36607 Microcystin-LR A potent protein phosphatase inhibitor
- GC36622 MK-0812 Succinate El succinato MK-0812 es un antagonista de CCR2 potente y selectivo con alta afinidad en CCR2.
- GC68230 MitoSOX Red
- GD08760 Dicamba
- GC16240 MNI-caged-NMDA NMDA caged with the photosensitive 4-methoxy-7-nitroindolinyl group
- GC11940 5-BrdU Synthetic thymidine analog
- GC19434 Pyropheophorbide a Pyropheophorbide a (Ppa) es un fotosensibilizador prometedor para la terapia fotodinámica tumoral (PDT).
- GC49499 5(Z)-Dodecenoic Acid El Ácido 5(Z)-dodecenoico es un metabolito endÓgeno con actividades inhibitorias contra COX-I y COX-II.
- GC63549 HBC599 HBC599 es un anÁlogo de HBC.
- GC60311 PTUPB PTUPB es un inhibidor potente y dual de las enzimas sEH y COX-2 con IC50 de 0,9 nM y 1,26 μM, respectivamente.
- GC43496 D-Luciferin (potassium salt) D-luciferin is the natural substrate of firefly luciferase.
- GC43497 D-Luciferin (sodium salt) D-luciferin is the natural substrate of firefly luciferase.
- GD16187 (-)-Methyl (S)-2,2-dimethyl-1,3-dioxolane-4-carboxylate
- GC26336 4,4'-(1,10-Phenanthroline-3,8-diyl)dibenzaldehyde
- GC67931 (+)-Medioresinol
- GC12138 5,15-DPP STAT3 inhibitor
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GC43291
Coelenterazine 400a (hydrochloride)
Coelenterazine 400a is a bisdeoxy derivative of coelenterazine that displays an emission maximum of 395 nm following conversion by Renilla luciferase (Rluc).
- GC64891 YM-341619 YM-341619 (AS1617612) es un inhibidor de STAT6 potente y activo por vÍa oral con una IC50 de 0,70 nM.
- GC15388 Glyoxylic acid El Ácido glioxÁlico (NSC 27785) es un compuesto orgÁnico que es tanto un aldehÍdo como un Ácido carboxÍlico.
- GK10008 Ultra High Sensitivity ECL Kit Luminol-based chemiluminescent kit for detection of horseradish peroxidase (HRP)-labeled antibodies and their associated antigens
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GC26308
Lactate Oxidase ( ≥80 units/mg solid)
Enzyme activity definition:One unit causes the formation of one micromole of hydrogen peroxide (half a micromole of quinoneimine dye) per minute under the conditions described below.
- GC43290 Coelenterazine 400a A bisdeoxy derivative of coelenterazine
- GC32745 OSS_128167 OSS_128167 is a potent selective silencing regulatory protein 6 (SIRT6) inhibitor with an IC50 of 89 μM.
- GB58280 Di-tert-butylchlorosilane
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GC60166
Fetuin, Fetal Bovine Serum
Fetuína, suero fetal bovino es una glicoproteína del suero fetal bovino, que a menudo es un suplemento importante para muchos medios libres de suero.
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GC16462
BYL-719
BYL-719 (BYL-719) es un inhibidor potente, selectivo y activo por vía oral de PI3Kα. BYL-719 (BYL-719) muestra eficacia en el tratamiento del cáncer mutado en PIK3CA. BYL-719 (BYL-719) también inhibe p110α/p110γ/p110δ/p110β con IC50s de 5/250/290/1200 nM, respectivamente. Actividad antineoplásica.
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GC14870
OSMI-1
OSMI-1 es un inhibidor de moléculas pequeñas de la transferasa O-GlcNAc (OGT) que no afecta significativamente a otras glicosiltransferasas.
- GB30168 ER-Tracker Red
- GC18406 Filipin Complex Filipin complex is a neutral polyene,it has antifungal activity.
- GC19976 TVB-3664 TVB-3664 is an orally available, reversible, potent, selective and highly bioavailable fatty acid synthase (FASN) inhibitor, with IC50 values of 18 nM and 12 nM for human and mouse cell palmitate synthesis, respectively.
- GC26335 Dipentene
- GC33975 Ampicillin (D-(-)-α-Aminobenzylpenicillin) La ampicilina es un antibiÓtico betalactÁmico de amplio espectro contra una variedad de bacterias grampositivas y gramnegativas.
- GC62723 ARV-471 ARV-471 es un degradador de proteÍna PROTAC del receptor de estrÓgeno oral para el cÁncer de mama. ARV-471 es una molécula heterobifuncional que facilita las interacciones entre el receptor de estrÓgeno alfa y un complejo de ligasa E3 intracelular. ARV-471 conduce a la ubiquitilaciÓn y posterior degradaciÓn de los receptores de estrÓgeno a través del proteasoma. ARV-471 degrada fuertemente ER en lÍneas celulares de cÁncer de mama ER-positivas con una concentraciÓn de degradaciÓn media mÁxima (DC50) de ~ 2 nM.
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GC34010
Danshensu (Dan shen suan A)
Danshensu, an active ingredient of Salvia miltiorrhiza, shows wide cardiovascular benefit by activating Nrf2 signaling pathway.
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GN10503
Piceatannol
Piceatannol (3,3′,4,5′-trans-trihydroxystilbene) is a naturally occurring hydroxylated analogue of resveratrol.
- GC39628 DB1976 hydrochloride El clorhidrato de DB1769 es un anÁlogo de selenofeno de DB270 y un inhibidor del factor de transcripciÓn PU.1 potente, permeable a las células y totalmente eficaz. El clorhidrato de DB1769 inhibe potentemente la uniÓn de PU.1 (IC50 de 10 nM) e inhibe fuertemente el complejo PU.1/ADN (con alta afinidad DB1769-ΛB, KD de 12 nM) in vitro. El clorhidrato de DB1769 tiene un efecto inductor de la apoptosis.
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GN10806
Vitexin
Vitexin is an active components of many traditional Chinese medicines, and were found in various medicinal plants.
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GC33093
Decoyinine (Angustmycin A)
Decoyinine is a selective inhibitor of GMP synthetase (GMPS).
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GN10533
Gracillin
Gracillin, as a natural steroidal saponin component of D. quinqueloba, has antitumour, antimicrobial, antioxidant, pro‐apoptotic and anti‐inflammatory properties.
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GC62661
PF-07104091 hydrate
PF-07104091 hydrate is a potent and selective CDK2/cyclin E1 and GSK3β inhibitor, with Kis of 1.16 and 537.81 nM, respectively.
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GN10667
Calycosin
Calycosin (CA, 7, 3-dihydroxy-4-methoxy isoflavone, C16H12O5) is one of the flavonoids extracted from astragalus root, also known as the typical phytoestrogens.
- GC30049 PLGA(75:25)(poly(lactic-co-glycolic acid)) PLGA (75:25) (poli (Ácido lÁctico-co-glicÓlico)) es un vehÍculo de liberaciÓn controlada de fÁrmacos de baja toxicidad, biocompatible y biodegradable, que puede lograr una liberaciÓn lenta en el organismo.
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GN10454
Methylophiopogonanone A
Methylophiopogonanone A (MOA), an abundantly bioactive homoisoflavonoid isolated from the herbal medicine Ophiopogonis Radix, has been considered as the key chemical index for the quality control of Ophiopogonis Radix related herbal formulations.
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GC14824
Sulfo-NHS-SS-Biotin
Sulfo-NHS-SS-biotin is an amine-reactive biotinylating reagent.
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GN10507
Baohuoside I
Baohuoside I, a flavonoid isolated from Epimedium koreanum Nakai, acts as an inhibitor of CXCR4, downregulates CXCR4 expression, induces apoptosis and shows anti-tumor activity.
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GC26334
SRI 37892
SRI 37892 is a small molecule compound inhibitor of Frizzled protein 7 (Fzd7) with inhibitory activity against cancer cell proliferation (IC502μM).
- GC32100 Tarloxotinib bromide (TH-4000) El bromuro de tarloxotinib (TH-4000) (TH-4000) es un inhibidor irreversible de EGFR/HER2.
- GC34252 GP(33-41) GP(33-41), un péptido de 9 aa de longitud, es la secuencia Óptima del epÍtopo GP1 del virus de la coriomeningitis linfocÍtica y puede aumentar las moléculas H-2Db en la superficie celular RMA-S (Db Kb) con una SC50 de 344 nM.
- GC32216 Squalene (Super Squalene) A biosynthetic precursor to steroids
- GN10244 Pterostilbene
- GF42684 1-Vinyl-3-benzyl imidazolium chlorine
- GC38304 (Z)-Aconitic acid El Ácido (Z)-aconÍtico (Ácido cis-aconÍtico) es el isÓmero cis del Ácido aconÍtico.
- GN10727 Forsythoside B
- GC33533 CEP dipeptide 1 El dipéptido 1 de CEP es un dipéptido de CEP con una potente actividad angiogénica; mediadores de la degeneraciÓn macular relacionada con la edad (AMD).
- GC10289 2-NBDG 2-NBDG is a fluorescence-labeled 2-deoxy-glucose analog useful as a tracer for evaluation of cellular glucose metabolism (Ex/Em: 475/550 nm).
- GD09164 3,5-Dimethylphenyl Isocyanate
- GC19631 8-bromo-Cyclic ADP-Ribose
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GP10049
Amyloid Beta-Peptide (12-28) (human)
Amyloid Beta-Peptide (12-28) (human) is a peptide fragment of amyloid beta protein (1-42) (Aβ (1-42)).
- GC30151 DFO (9H-1,8-Diazafluoren-9-one) DFO (9H-1,8-Diazafluoren-9-one) (DFO) es una sustancia quÍmica que se utiliza para encontrar huellas dactilares en superficies porosas.