- Cat.No. 상품명 정보
- GC38036 PIN1 inhibitor API-1 PIN1 억제제 API-1은 IC50이 72.3nM인 특정 Pin1(펩티딜-프롤릴 시스-트랜스 이성질화효소 NIMA-상호작용 1) 억제제(API-1)입니다. PIN1 억제제 API-1은 Pin1 펩티딜-프롤릴 이성화효소(PPIase) 도메인에 직접 및 특이적으로 결합하여 Pin1 시스-트랜스 이성화 활성을 강력하게 억제합니다. PIN1 억제제 API-1은 pXPO5의 활성 형태를 유지하고 pXPO5가 pre-miRNA를 핵에서 세포질로 수송하는 능력을 복원하여 항암 miRNA 생합성을 상향 조절하여 시험관 내 및 생체 내 간세포 암종 발병을 모두 억제합니다.
- GA22331 Hepcidin-25 (human) Hepcidin-25 (hepatic bactericidal protein), also referred to as LEAP-1 (liver-expressed antimicrobial peptide) has been independently discovered by two groups in human blood ultrafiltrate and urine. The peptide which is predominantly expressed in the liver, belongs to a new vertebrate family of small antimicrobial peptides that contain 8 cysteine residues and show significant antibacterial and antifungal activity. Further investigations revealed that hepicidin is the principal iron-regulatory hormone in humans. Hepcidin acts by binding to the iron exporter ferroportin, inducing its internalization and degradation, thereby blocking cellular iron efflux. Nemeth et al. demonstrated that the N-terminal part of the peptide hormone is essential for its activity. Former CAS-number 342790-21-0.
- GF04824 perampanel 3/4 hydrate
- GC42443 4-Methylumbelliferyl 6-thio-Palmitate-β-D-Glucopyranoside A fluorogenic substrate of PPT/CLN1
- GC43892 Ikarugamycin Ikarugamycin은 항생제이자 클라트린 매개 세포내이입(CME)의 억제제입니다.
-
GC41184
1P-LSD (solution)
1P-LSD (solution) is an analytical reference material categorized as a lysergamide.
- GC46049 1cP-LSD (solution) An Analytical Reference Material
- GC26342 Triflusulfuron-methyl
- GC26341 Cupric hydroxide, AR
- GC26340 2-(2-Chloro-4-(methylsulfonyl)-3-((2,2,2-trifluoroethoxy)methyl)benzoyl)cyclohexane-1,3-dione
- GC26339 Mesosulfuron-Methyl
- GC30025 Dihydroethidium (Hydroethidine) Dihydroethdium(Hydroethidine) (DHE) oxidation is commonly used as a method for monitoring cellular production of "reactive oxygen species (ROS)".
- GC26338 α-Cypermethrin
- GC40775 Dexamethasone Dexamethasone, as one member of the glucocorticoid family, can protect against arthritis-related changes in cartilage structure and function, including matrix loss, inflammation and cartilage viability.
- GC15948 Prostaglandin E2 Prostaglandin E2 is a major metabolite produced from arachidonic acid catalyzed by Cyclooxygenase (COX).
-
GC10839
Tubastatin A
A potent HDAC6 inhibitor
- GF28637 4-(4-Hydroxyphenyl)butanoic acid
- GC11421 L-364,373 KV7.1 (KCNQ1) channel activator
- GC36980 Propranolol Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively.
- GC30231 Fluo-4 AM A fluorescent calcium indicator
- GK10009 BCA Protein Assay Kit BCA Protein Assay Kit is a ready-to-use total protein content determination kit with a detection range of 20-2000μg/mL.
- GC63213 TDI-10229 TDI-10229는 가용성 아데닐릴 사이클라제(sAC, ADCY10)의 강력한 경구 생체이용 억제제입니다.
- GC26337 REHMANNIAE RADIX PRAEPARATA
- GC17476 MRS 2500 tetraammonium salt Highly potent and selective antagonist of the platelet P2Y1 receptor
- GC15332 Ticagrelor P2Y12 receptor antagonist
- GC41578 cis-10-Heptadecenoic Acid A monounsaturated fatty acid
- GC67352 (tert-Butoxycarbonyl)-D-cysteine (tert-Butoxycarbonyl)-D-cysteine은 시스테인 유도체입니다.821d96072c2d58d8970e76f526b0f6b8
- GC36881 PF-04937319 PF-04937319는 EC50 값이 154.4 μM인 GKA(글루코키나아제 활성화제)로, 제2형 당뇨병 치료를 위한 가장 유망한 전략 중 하나입니다.
- GC60064 AZD1656 AZD1656은 60nM의 EC50을 갖는 강력하고 선택적이며 경구 활성인 글루코키나제 활성제입니다.
- GC18280 13(E)-Docosenoic Acid A 22-carbon monounsaturated fatty acid
- GC49723 SenTraGor™ Cell Senescence Reagent A cellular senescence detection reagent
- GK10027 Bradford Protein Quantification Kit (Ready to use) The Bradford Protein Quantification Kit is a kit for rapid determination of protein concentrations in the range of 0.025-2mg/ml.
- GB53529 2-(2-(2-Methoxyethoxy)ethoxy)ethyl acrylate
- GC36816 Ornidazole Levo- 오르니다졸 레보-는 오르니다졸의 레보 이성질체입니다.
- GC49141 Triacontanoic Acid A very long-chain saturated fatty acid
- GC19881 Golgi-Tracker Red Golgi red fluorescent probe, one of the sphingolipid fluorescent probes, which can be used for Golgi-specific fluorescent staining of living cells.
- GC15137 RS 56812 hydrochloride 5-HT3 partial agonist
- GC16162 ICI 162,846 histamine H2 receptor antagonist
- GC50009 LY 294002 hydrochloride Prototypical PI 3-kinase inhibitor; also inhibits other kinases
- GK10001 Cell Counting Kit-8 (CCK-8) Cell Counting Kit-8 (CCK-8) is a ready-to-use one-bottle solution which offers a simple, rapid, reliable and sensitive measurement of cell viability and cytotoxicity of various chemicals.
- GC61473 Trastuzumab deruxtecan An HER2 antibody-drug conjugate (ADC)
- GC36607 Microcystin-LR A potent protein phosphatase inhibitor
- GC36622 MK-0812 Succinate MK-0812 Succinate는 CCR2에서 높은 친화력을 가진 강력하고 선택적인 CCR2 길항제입니다.
- GC68230 MitoSOX Red
- GD08760 Dicamba
- GC16240 MNI-caged-NMDA NMDA caged with the photosensitive 4-methoxy-7-nitroindolinyl group
- GC11940 5-BrdU Synthetic thymidine analog
- GC19434 Pyropheophorbide a Pyropheophorbide a(Ppa)는 종양 광역학 요법(PDT)에 대한 유망한 광감작제입니다.
- GC49499 5(Z)-Dodecenoic Acid 5(Z)-도데센산은 COX-I 및 COX-II에 대한 억제 활성을 갖는 내인성 대사 산물입니다.
- GC63549 HBC599 HBC599는 HBC 아날로그입니다.
- GC60311 PTUPB PTUPB는 IC50이 각각 0.9nM 및 1.26μM인 강력한 이중 sEH 및 COX-2 효소 억제제입니다.
- GC43496 D-Luciferin (potassium salt) D-luciferin is the natural substrate of firefly luciferase.
- GC43497 D-Luciferin (sodium salt) D-luciferin is the natural substrate of firefly luciferase.
- GD16187 (-)-Methyl (S)-2,2-dimethyl-1,3-dioxolane-4-carboxylate
- GC26336 4,4'-(1,10-Phenanthroline-3,8-diyl)dibenzaldehyde
- GC67931 (+)-Medioresinol
- GC12138 5,15-DPP STAT3 inhibitor
-
GC43291
Coelenterazine 400a (hydrochloride)
Coelenterazine 400a is a bisdeoxy derivative of coelenterazine that displays an emission maximum of 395 nm following conversion by Renilla luciferase (Rluc).
- GC64891 YM-341619 YM-341619(AS1617612)는 IC50이 0.70nM인 강력한 경구 활성 STAT6 억제제입니다.
- GC15388 Glyoxylic acid 글리옥살산(NSC 27785)은 알데히드와 카르복실산인 유기 화합물입니다.
- GK10008 Ultra High Sensitivity ECL Kit Luminol-based chemiluminescent kit for detection of horseradish peroxidase (HRP)-labeled antibodies and their associated antigens
-
GC26308
Lactate Oxidase ( ≥80 units/mg solid)
Enzyme activity definition:One unit causes the formation of one micromole of hydrogen peroxide (half a micromole of quinoneimine dye) per minute under the conditions described below.
- GC43290 Coelenterazine 400a A bisdeoxy derivative of coelenterazine
- GC32745 OSS_128167 OSS_128167 is a potent selective silencing regulatory protein 6 (SIRT6) inhibitor with an IC50 of 89 μM.
- GB58280 Di-tert-butylchlorosilane
-
GC60166
Fetuin, Fetal Bovine Serum
페튀인(Fetuin)은 태아 소혈청에서 유래된 당단백질로, 많은 무혈청 배지에 중요한 보충제입니다.
-
GC16462
BYL-719
BYL-719 (BYL-719)은 강력하고 선택적이며 경구 투여 가능한 PI3Kα 억제제입니다. BYL-719 (BYL-719)는 PIK3CA 돌연변이 암을 대상으로 효과를 보입니다. BYL-719 (BYL-719)는 또한 p110α/p110β/p110δ/p110γ를 각각 5/250/290/1200 nM의 IC50로 억제합니다. 항신생물학적 활동을 나타냅니다.
-
GC14870
OSMI-1
OSMI-1은 다른 당분 전이효소에 큰 영향을 미치지 않는 O-GlcNAc 전이효소(OGT) 소분자 억제제입니다.
- GB30168 ER-Tracker Red
- GC18406 Filipin Complex Filipin complex is a neutral polyene,it has antifungal activity.
- GC19976 TVB-3664 TVB-3664 is an orally available, reversible, potent, selective and highly bioavailable fatty acid synthase (FASN) inhibitor, with IC50 values of 18 nM and 12 nM for human and mouse cell palmitate synthesis, respectively.
- GC26335 Dipentene
- GC33975 Ampicillin (D-(-)-α-Aminobenzylpenicillin) 암피실린은 다양한 그람 양성 및 그람 음성 박테리아에 대한 광범위한 베타 락탐 항생제입니다.
- GC62723 ARV-471 ARV-471은 유방암에 대한 경구 에스트로겐 수용체 PROTAC 단백질 분해제입니다. ARV-471은 에스트로겐 수용체 알파와 세포내 E3 리가제 복합체 사이의 상호작용을 촉진하는 이종이기능성 분자입니다. ARV-471은 프로테아좀을 통한 에스트로겐 수용체의 유비퀴틸화 및 후속 분해를 유도합니다. ARV-471은 ~2nM의 절반 최대 분해 농도(DC50)로 ER 양성 유방암 세포주에서 ER을 강력하게 분해합니다.
-
GC34010
Danshensu (Dan shen suan A)
Danshensu, an active ingredient of Salvia miltiorrhiza, shows wide cardiovascular benefit by activating Nrf2 signaling pathway.
-
GN10503
Piceatannol
Piceatannol (3,3′,4,5′-trans-trihydroxystilbene) is a naturally occurring hydroxylated analogue of resveratrol.
- GC39628 DB1976 hydrochloride DB1769 염산염은 DB270의 셀레노펜 유사체이며 강력하고 세포 투과성이 있으며 완전히 효과적인 전사 인자 PU.1 억제제입니다. DB1769 염산염은 시험관 내에서 PU.1 결합(IC50 10nM)을 강력하게 억제하고 PU.1/DNA 복합체(높은 DB1769-ΛB 친화성, KD 12nM)를 강력하게 억제합니다. DB1769 염산염은 세포 사멸 유도 효과가 있습니다.
-
GN10806
Vitexin
Vitexin is an active components of many traditional Chinese medicines, and were found in various medicinal plants.
-
GC33093
Decoyinine (Angustmycin A)
Decoyinine is a selective inhibitor of GMP synthetase (GMPS).
-
GN10533
Gracillin
Gracillin, as a natural steroidal saponin component of D. quinqueloba, has antitumour, antimicrobial, antioxidant, pro‐apoptotic and anti‐inflammatory properties.
-
GC62661
PF-07104091 hydrate
PF-07104091 hydrate is a potent and selective CDK2/cyclin E1 and GSK3β inhibitor, with Kis of 1.16 and 537.81 nM, respectively.
-
GN10667
Calycosin
Calycosin (CA, 7, 3-dihydroxy-4-methoxy isoflavone, C16H12O5) is one of the flavonoids extracted from astragalus root, also known as the typical phytoestrogens.
- GC30049 PLGA(75:25)(poly(lactic-co-glycolic acid)) PLGA(75:25)(poly(lactic-co-glycolic acid))는 낮은 독성, 생체 적합성 및 생분해성 제어 약물 전달 운반체이며 유기체에서 느린 방출을 달성할 수 있습니다.
-
GN10454
Methylophiopogonanone A
Methylophiopogonanone A (MOA), an abundantly bioactive homoisoflavonoid isolated from the herbal medicine Ophiopogonis Radix, has been considered as the key chemical index for the quality control of Ophiopogonis Radix related herbal formulations.
-
GC14824
Sulfo-NHS-SS-Biotin
Sulfo-NHS-SS-biotin is an amine-reactive biotinylating reagent.
-
GN10507
Baohuoside I
Baohuoside I, a flavonoid isolated from Epimedium koreanum Nakai, acts as an inhibitor of CXCR4, downregulates CXCR4 expression, induces apoptosis and shows anti-tumor activity.
-
GC26334
SRI 37892
SRI 37892 is a small molecule compound inhibitor of Frizzled protein 7 (Fzd7) with inhibitory activity against cancer cell proliferation (IC502μM).
- GC32100 Tarloxotinib bromide (TH-4000) 탈록소티닙 브로마이드(TH-4000)(TH-4000)는 비가역적 EGFR/HER2 억제제입니다.
- GC34252 GP(33-41) 9aa 길이의 펩타이드인 GP(33-41)는 림프구성 맥락수막염 바이러스의 GP1 에피토프의 최적 서열이며, SC50의 SC50으로 RMA-S(Db Kb) 세포 표면에서 H-2Db 분자를 상향조절할 수 있습니다. 344nM.
- GC32216 Squalene (Super Squalene) A biosynthetic precursor to steroids
- GN10244 Pterostilbene
- GF42684 1-Vinyl-3-benzyl imidazolium chlorine
- GC38304 (Z)-Aconitic acid (Z)-아코니트산(시스-아코니트산)은 아코니트산의 시스-이성체입니다.
- GN10727 Forsythoside B
- GC33533 CEP dipeptide 1 CEP 디펩티드 1은 강력한 혈관신생 활성을 가진 CEP 디펩티드입니다. 연령 관련 황반변성(AMD)의 매개체.
- GC10289 2-NBDG 2-NBDG is a fluorescence-labeled 2-deoxy-glucose analog useful as a tracer for evaluation of cellular glucose metabolism (Ex/Em: 475/550 nm).
- GD09164 3,5-Dimethylphenyl Isocyanate
- GC19631 8-bromo-Cyclic ADP-Ribose
-
GP10049
Amyloid Beta-Peptide (12-28) (human)
Amyloid Beta-Peptide (12-28) (human) is a peptide fragment of amyloid beta protein (1-42) (Aβ (1-42)).
- GC30151 DFO (9H-1,8-Diazafluoren-9-one) DFO(9H-1,8-Diazafluoren-9-one)(DFO)는 다공성 표면에서 지문을 찾는 데 사용되는 화학 물질입니다.