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Home >> Signaling Pathways >> Apoptosis >> Other Apoptosis

Other Apoptosis

Products for  Other Apoptosis

  1. Cat.No. Product Name Information
  2. GC11496 TLQP 21 TLQP 21 Chemical Structure
  3. GC18173 TM5441 TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor 1 (PAI-1), a serine-protease inhibitor involved in thrombosis. TM5441 Chemical Structure
  4. GC17586 Tofacitinib (CP-690550) Citrate

    CP 690,550

     A pan-JAK inhibitor Tofacitinib (CP-690550) Citrate Chemical Structure
  5. GC13359 Topotecan HCl

    NSC 609669, SKF 104864A

     Topotecan HCl (SKF 104864A Hydrochloride) is a Topoisomerase I inhibitor with potent antineoplastic activities. Topotecan HCl Chemical Structure
  6. GC13835 Toremifene Citrate

    GTx-006, NK 622, NSC 613680

     Oral selective estrogen receptor modulator (SERM) Toremifene Citrate Chemical Structure
  7. GC13858 Torin 2 MTOR inhibitor,highly potent and selective Torin 2 Chemical Structure
  8. GC14218 TP-0903

    TP-0903

     TP-0903 (TP-0903) is a potent and selective Axl receptor tyrosine kinase inhibitor with an IC50 value of 27 nM. TP-0903 Chemical Structure
  9. GC18044 Trabectedin

    Ecteinascidin 743, ET-743, NSC 648766

     An alkaloid with anticancer activity Trabectedin Chemical Structure
  10. GC13508 Trametinib (GSK1120212)

    GSK1120212, JTP-74057

    An inhibitor of MEK1 and MEK2

     Trametinib (GSK1120212) Chemical Structure
  11. GC14402 Triptolide

    NSC 163062, PG 490

     Triptolide is a diterpenoid triepoxide extracted from the root of Thunder God Vine, acting as an inhibitor of NF-κB activation. NF-κB is a family of transcription factor protein complexes. Triptolide Chemical Structure
  12. GC15272 Troglitazone Selective PPARγ agonist Troglitazone Chemical Structure
  13. GC19457 Trolox

    6hydroxy2,5,7,8tetramethylchroman2Carboxylic Acid

     Trolox is a cell-permeable, water-soluble derivative of vitamin E with potent antioxidant properties. Trolox Chemical Structure
  14. GC16732 TSU-68 (SU6668,Orantinib)

    NSC 702827, Orantinib, TSU68

     TSU-68 (SU6668,Orantinib) (SU6668; TSU-68) is a multi-targeted receptor tyrosine kinase inhibitor with Kis of 2.1 μM, 8 nM and 1.2 μM for Flt-1, PDGFRβ and FGFR1, respectively. TSU-68 (SU6668,Orantinib) Chemical Structure
  15. GC14273 TTNPB (Arotinoid Acid)

    AGN 191183, Arotinoid Acid, Ro 13-7410

     TTNPB (Arotinoid Acid) is a highly potent RAR agonist. Competitive binding assays using human RARs yield IC50s of α=5.1 nM, β= 4.5 nM, and γ=9.3 nM, respectively. TTNPB (Arotinoid Acid) Chemical Structure
  16. GC10839 Tubastatin A

    A potent HDAC6 inhibitor

     Tubastatin A Chemical Structure
  17. GN10107 Tubeimoside I

    Lobatoside H, Tubeimoside A

     Tubeimoside I Chemical Structure
  18. GC33291 Tubulin inhibitor 1 Tubulin inhibitor 1 is a tubulin inhibitor, inhibits tubulin polymerization. Tubulin inhibitor 1 shows potent anti-tumor activity, casues cellular mitotic arrest in the G2/M phase, and induces cellular apoptosis. Tubulin inhibitor 1 Chemical Structure
  19. GC33155 Tubulysin A (TubA) Tubulysin A (TubA)(TubA) is a myxobacterial product that can function as an antiangiogenic agent in many in vitro assays; anti-microtubule, anti-mitotic, an apoptosis inducer, anticancer, anti-angiogenic, and antiproliferative. Tubulysin A (TubA) Chemical Structure
  20. GC37836 Tubulysin B Tubulysin B Chemical Structure
  21. GC37837 Tubulysin C Tubulysin C is a highly cytotoxic peptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis. Tubulysin displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC50 values in the lower nanomolar range. Tubulysin C is a cytotoxic activity tubulysin which inhibits tubulin polymerization and leads to cell cycle arrest and apoptosis. Tubulysin C Chemical Structure
  22. GC37839 Tubulysin E Tubulysin E is a highly cytotoxic peptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis. Tubulysin displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC50 values in the lower nanomolar range. Tubulysin E is a cytotoxic activity tubulysin which inhibits tubulin polymerization and leads to cell cycle arrest and apoptosis. Tubulysin E Chemical Structure
  23. GC37840 Tubulysin F Tubulysin F is a highly cytotoxic peptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis. Tubulysin displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC50 values in the lower nanomolar range. Tubulysin F is a cytotoxic activity tubulysin which inhibits tubulin polymerization and leads to cell cycle arrest and apoptosis. Tubulysin F Chemical Structure
  24. GC37841 Tubulysin G Tubulysin G is a highly cytotoxic peptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis. Tubulysin displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC50 values in the lower nanomolar range. Tubulysin G is a cytotoxic activity tubulysin which inhibits tubulin polymerization and leads to cell cycle arrest and apoptosis. Tubulysin G Chemical Structure
  25. GC37842 Tubulysin H Tubulysin H is a highly cytotoxic peptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis. Tubulysin displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC50 values in the lower nanomolar range. Tubulysin H is a cytotoxic activity tubulysin which inhibits tubulin polymerization and leads to cell cycle arrest and apoptosis. Tubulysin H Chemical Structure
  26. GC37843 Tubulysin I Tubulysin I is a highly cytotoxic peptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis. Tubulysin displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC50 values in the lower nanomolar range. Tubulysin I is a cytotoxic activity tubulysin which inhibits tubulin polymerization and leads to cell cycle arrest and apoptosis. Tubulysin I Chemical Structure
  27. GC37844 Tubulysin M Tubulysin M is a highly cytotoxic peptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis. Tubulysin displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC50 values in the lower nanomolar range. Tubulysin M is a cytotoxic activity tubulysin which inhibits tubulin polymerization and leads to cell cycle arrest and apoptosis. Tubulysin M Chemical Structure
  28. GC38710 TVB-3166 A FASN inhibitor TVB-3166 Chemical Structure
  29. GC15271 Tyrphostin AG 879

    Tyrphostin AG879

     HER2 inhibitor Tyrphostin AG 879 Chemical Structure
  30. GC10601 Ubiquitin Isopeptidase Inhibitor I

    NSC 144303

     Ubiquitin Isopeptidase Inhibitor I (NSC 144303) is an apoptosome-independent caspase and apoptosis activator with IC50 values of 1.76 and 1.6 μM in E1A and E1A/C9DN cells, respectively. Ubiquitin Isopeptidase Inhibitor I Chemical Structure
  31. GC16479 UC 112 IAP inhibitor UC 112 Chemical Structure
  32. GN10506 Umbelliferone

    7-hydroxy Coumarin, NSC 19790

     Umbelliferone Chemical Structure
  33. GC16794 UNC1215

    UNC 1215;UNC-1215

     Potent L3MBTL3 domain inhibitor UNC1215 Chemical Structure
  34. GC15168 Urolithin A

    2',7-Dihydroxy-3,4-benzocoumarin, 3,8-Dihydroxy Urolithin

     A gut-microbial metabolite of ellagic acid Urolithin A Chemical Structure
  35. GC37873 Ursonic acid Ursolic acid, a naturally occurring triterpenoid, induces the apoptosis of human cancer cells through multiple signaling pathways. Ursonic acid Chemical Structure
  36. GC38374 Uvarigrin Uvarigrin, isolated from the roots of Uvaria calamistrata, induces tumor multidrug resistance cell apoptosis and triggers Caspase-9 activation. Uvarigrin Chemical Structure
  37. GC16948 Valinomycin

    NSC 122023

     Valinomycin is a cyclic depsipeptide antibiotic with potassium selective ionophoric activity. It can be used as uncoupling agent to induce depolarization.. Valinomycin Chemical Structure
  38. GC15022 Vandetanib (ZD6474)

    ZD6474

     Vandetanib (ZD6474) (D6474) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity (IC50=40 nM). Vandetanib (ZD6474) also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC50=110 nM) and EGFR/HER1 (IC50=500 nM). Vandetanib (ZD6474) Chemical Structure
  39. GC37887 Vanillyl alcohol Vanillyl alcohol (p-(Hydroxymethyl)guaiacol), derived from vanillin, is a phenolic alcohol and is used as a flavoring agent in foods and beverages. Vanillyl alcohol Chemical Structure
  40. GC17955 Vatalanib (PTK787) 2HCl

    CGP 79787, PTK787, PTK/ZK

     Vatalanib (PTK787) 2HCl (PTK787 dihydrochloride) is an inhibitor of VEGFR2/KDR with IC50 of 37 nM. Vatalanib (PTK787) 2HCl Chemical Structure
  41. GC10501 VER-50589 HSP90 inhibitor, potent VER-50589 Chemical Structure
  42. GC13232 Verbascoside

    Acteoside, NSC 603831

     PKC/NF-κB inhibitor Verbascoside Chemical Structure
  43. GC37900 Verubulin Verubulin (MPC-6827) is a microtubule-disrupting agent with potent and broad-spectrum in vitro and in vivo cytotoxic activities, and acts as a promising candidate for the treatment of multiple cancer types. Verubulin Chemical Structure
  44. GC16733 Vildagliptin (LAF-237)

    LAF237, NVP-LAF237

     A DPP-4 inhibitor Vildagliptin (LAF-237) Chemical Structure
  45. GC11511 Vincristine sulfate

    Kyocristine, Lilly 37231, Leurocristine, Novopharm, NSC 67574, Oncovin, VCR

     Microtubule disrupter,antitumor agent Vincristine sulfate Chemical Structure
  46. GC34021 Vitamin K4 (acetomenaphthone)

    Acetomenaphthone, Menadiol diacetate, NSC 403062, Vitamin K diacetate

     Vitamin K4 (acetomenaphthone) is a chemically synthesized Vitamin K which plays an important role in the normal blood coagulation system. Vitamin K4 (acetomenaphthone) Chemical Structure
  47. GC13544 Voreloxin

    SNS-595, Voreloxin

     An inhibitor of topoisomerase II Voreloxin Chemical Structure
  48. GC14022 Voreloxin Hydrochloride Voreloxin Hydrochloride Chemical Structure
  49. GC12003 VR23 proteasome inhibitor VR23 Chemical Structure
  50. GN10269 Wedelolactone

    IKK Inhibitor II

     Wedelolactone Chemical Structure
  51. GC15589 WHI-P154

    JAK3 Inhibitor II, JanusAssociated Kinase 3 Inhibitor II

     A JAK3 inhibitor WHI-P154 Chemical Structure
  52. GN10017 Wogonin

    BRN 0287152

     Wogonin Chemical Structure
  53. GC15980 WP1066

    STAT Inhibitor III

    An inhibitor of STAT3

     WP1066 Chemical Structure
  54. GC10970 WP1130

    WP 1130; WP-1130

     WP1130 (WP1130) is a cell-permeable deubiquitinase (DUB) inhibitor, directly inhibiting DUB activity of USP9x, USP5, USP14, and UCH37. WP1130 has been shown to downregulate the antiapoptotic proteins Bcr-Abl and JAK2. WP1130 Chemical Structure
  55. GC18206 WT161 WT161 is a potent inhibitor of HDAC6 with an IC50 value of 0.40 nM. WT161 Chemical Structure
  56. GC34862 WYC-209 WYC-209, a synthetic retinoid, is a retinoic acid receptor (RAR) agonist. WYC-209 induces apoptosis primarily via the caspase 3 pathway (IC50=0.19?μM for inmalignant murine melanoma TRCs), and has long-term effects with little toxicity. WYC-209 Chemical Structure
  57. GC14675 WYE-125132 (WYE-132)

    WYE-132

     WYE-125132 (WYE-132) (WYE-125132) is a highly potent, ATP-competitive, and specific mTOR kinase inhibitor (IC50: 0.19±0.07 nM; >5,000-fold selective versus PI3Ks). WYE-125132 (WYE-132) (WYE-125132) inhibits mTORC1 and mTORC2. WYE-125132 (WYE-132) Chemical Structure
  58. GC12391 Xanthohumol VCP inhibitor Xanthohumol Chemical Structure
  59. GC11459 Xanthurenic acid

    NSC 401570, Xanthurenate

     group II mGlu receptor activator Xanthurenic acid Chemical Structure
  60. GC14327 XL019

    XL-019;XL 019

     A potent, bioavailable JAK2 inhibitor XL019 Chemical Structure
  61. GC12709 XL147

    Pilaralisib, SAR245408

     XL147 (XL147 analogue) is a representative and selective PI3Kα inhibitor extracted from patent WO2012006552A1, Compound 147 in Table 1. XL147 Chemical Structure
  62. GC10512 Y-27632 dihydrochloride

    y-27632, Y27632, Y-27632 dihydrochloride, Y 27632

    A ROCK inhibitor

     Y-27632 dihydrochloride Chemical Structure
  63. GC11445 YH239-EE p53-MDM2 antagonist, potent YH239-EE Chemical Structure
  64. GC17386 YK-4-279

    YK 4-279

     YK-4-279 Chemical Structure
  65. GC10195 Z-Guggulsterone

    Z-Guggulsterone suppresses angiogenesis in vitro and in vivo with IC50 values of 1740, 1000, 220 and > 50000 nM for glucocorticoid, mineralocorticoid, androgen and farnesoid X receptors .

     Z-Guggulsterone Chemical Structure
  66. GC15896 Z-Ile-Leu-aldehyde

    Z-IL-CHO; GSI-XII; γ-Secretase inhibitor XII

     potent gamma-Secretase inhibitor Z-Ile-Leu-aldehyde Chemical Structure
  67. GC37964 Zeylenone Zeylenone, a naturally occurring cyclohexene oxide, inhibits proliferation and induces apoptosis in cervical carcinoma cells via PI3K/AKT/mTOR and MAPK/ERK pathways. Zeylenone Chemical Structure
  68. GN10203 Ziyuglycoside I

    Gouguside 7

     Ziyuglycoside I Chemical Structure
  69. GN10650 Ziyuglycoside II Ziyuglycoside II Chemical Structure
  70. GC14409 ZM 447439 Selective inhibitor of Aurora B kinase ZM 447439 Chemical Structure
  71. GC13286 ZM336372 C-Raf inhibitor, potent and selective ZM336372 Chemical Structure
  72. GC35013 [8]-Shogaol [8]-Shogaol, one of the pungent phenolic compounds in ginger, exhibits anti-platelet activity (IC50=5 μM) and inhibits COX-2 (IC50=17.5 μM). [8]-Shogaol induces apoptosis in human leukemia cells. [8]-Shogaol Chemical Structure
  73. GC35305 α-Bisabolol

    DL-α-Bisabolol

     α-Bisabolol is a nontoxic sesquiterpene alcohol present in natural essential oil, with anticancer activity. α-Bisabolol exerts selective anticancer effect on A549 NSCLC cells (IC50=15 μM) via induction of cell cycle arrest, mitochondrial apoptosis and inhibition of PI3K/Akt signalling pathways. α-Bisabolol also strongly induces apoptosis in glioma cells. α-Bisabolol Chemical Structure
  74. GN10560 α-hederin

    Kalopanaxsaponin A, Koronaroside A, NSC 106553

     α-hederin Chemical Structure
  75. GN10547 β-Sitosterol

    Azuprostat, Betaprost, Cupreol, NSC 18173, NSC 49083, NSC 8096, Rhamnol, β-Sitosterol, SKF 14463, 22,23dihydroStigmasterol

     β-Sitosterol Chemical Structure

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