(±)11(12)-EpETE (Synonyms: (±)11,12-EEQ, (±)11,12-Epoxyeicosatetraenoic Acid) |
| Catalog No.GC40386 |
Eicosapentaenoic acid is converted to epoxyeicosatetraenoic acids (EpETE) by several cytochrome P450 isoforms.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 504435-15-8
Sample solution is provided at 25 µL, 10mM.
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Eicosapentaenoic acid is converted to epoxyeicosatetraenoic acids (EpETE) by several cytochrome P450 isoforms. The major product of this epoxygenase pathway, (±)17(18)-EpETE , relaxes vascular and airway smooth muscle by binding large conductance Ca2+-activated K+ (BKCa) channels by directly interacting with BKα channel subunits. (±)11(12)-EpETE is an epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo. The biological actions and physiological effects of this epoxide remain to be determined.
Average Rating: 5 (Based on Reviews and 37 reference(s) in Google Scholar.)
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