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Home >> Signaling Pathways >> Tyrosine Kinase >> Insulin Receptor

Insulin Receptor

Insulin receptor is a transmembrane receptor tyrosine kinase that mediates the insulin function and involved in the regulation of cell differentiation, growth and metabolism etc.

Products for  Insulin Receptor

  1. Cat.No. Product Name Information
  2. GC72195 (Pro3) GIP, human TFA (Pro3) GIP, human TFA is an efficacious, stable and specifichuman GIP receptor (hGIPR)full agonist. (Pro3) GIP, human TFA Chemical Structure
  3. GC50157 6bK Insulin degrading enzyme (IDE) inhibitor 6bK Chemical Structure
  4. GC68604 Acetyl Gastric Inhibitory Peptide (human) (TFA)

    Human N-acetyl GIP TFA

    Acetyl Gastric Inhibitory Peptide (human) TFA is a fatty acid derivative analog of glucose-dependent insulinotropic polypeptide, which has improved anti-hyperglycemic and insulinotropic properties. Acetyl Gastric Inhibitory Peptide (human) TFA can be used for research on diabetes, insulin resistance, and obesity.

     Acetyl Gastric Inhibitory Peptide (human) (TFA) Chemical Structure
  5. GC31371 AGL-2263 An inhibitor of IGF-1R AGL-2263 Chemical Structure
  6. GC64683 AVJ16 AVJ16 is a member of the insulin-like growth factor 2 mRNA-binding protein family. AVJ16 regulates protein translation by binding to the mRNAs of certain genes. AVJ16 Chemical Structure
  7. GC17773 BMS-536924

    IR/IGF-1R inhibitor

     BMS-536924 Chemical Structure
  8. GC16712 BMS-754807 IGF-1R/InsR inhibitor,potent and selective BMS-754807 Chemical Structure
  9. GC45789 Ceritinib-d7

    LDK 378-d7

     An internal standard for the quantification of ceritinib Ceritinib-d7 Chemical Structure
  10. GC68888 CMX-2043

    CMX-2043 is a new analogue of alpha-lipoic acid. It has antioxidant properties and can activate insulin receptor kinase, soluble tyrosine kinase, and promote Akt phosphorylation. CMX-2043 has shown protective effects in a rat model of ischemia-reperfusion injury (IRI).

     CMX-2043 Chemical Structure
  11. GC62712 DA-JC4 DA-JC4 is a dual GLP-1/GIP receptor agonist and can be used for the research of neurological disease and insulin signaling pathways. DA-JC4 Chemical Structure
  12. GC14905 Demethylasterriquinone B1

    DMAQ B1,L-783,281

    An insulin receptor (IR) activator

     Demethylasterriquinone B1 Chemical Structure
  13. GA21893 Gastric Inhibitory Polypeptide (1-30) amide (porcine) Gastric Inhibitory Polypeptide (1-30) amide (porcine) is a full glucose-dependent insulinotropic polypeptide (GIP) receptor agonist with high affinity equal to native GIP(1-42). Gastric Inhibitory Polypeptide (1-30) amide (porcine) Chemical Structure
  14. GA21894 Gastric Inhibitory Polypeptide (3-42) (human) Gastric Inhibitory Polypeptide (3-42) (human) acts as a glucose-dependent insulinotropic polypeptide (GIP) receptor antagonist, moderating the insulin secreting and metabolic actions of GIP in vivo. Gastric Inhibitory Polypeptide (3-42) (human) Chemical Structure
  15. GC61569 GIP (1-30) amide, porcine TFA GIP (1-30) amide, porcine TFA is a full glucose-dependent insulinotropic polypeptide (GIP) receptor agonist with high affinity equal to native GIP(1-42). GIP (1-30) amide, porcine TFA Chemical Structure
  16. GC60175 GIP (1-30) amide,Human acetate GIP (1-30) amide,human acetate is a glucose-dependent insulinotropic polypeptide (GIP) fragment. GIP (1-30) amide,Human acetate Chemical Structure
  17. GC61741 GIP, human TFA GIP, human TFA, a peptide hormone consisting of 42 amino acids, is a stimulator of glucose-dependent insulin secretion and a weak inhibitor of gastric acid secretion. GIP, human TFA Chemical Structure
  18. GC12273 GSK1838705A IGF-IR/IR/ALK inhibitor, ATP-competitive GSK1838705A Chemical Structure
  19. GC14654 HNGF6A increases glucose stimulated insulin secretion and glucose metabolism HNGF6A Chemical Structure
  20. GC13988 HNMPA

    Hydroxy-2-naphthalenylmethyl Phosphonic Acid

     cell impermeable tyrosine kinase inhibitor HNMPA Chemical Structure
  21. GC72106 human GIP(3-30), amide TFA human GIP(3-30), amide TFA is a high affinity antagonist of the human GIP receptor in vitro. human GIP(3-30), amide TFA Chemical Structure
  22. GC73612 IGF2BP1-IN-1 IGF2BP1-IN-1 (Compound A11) is a IGF2BP1 inhibitor and inhibits downstream signaling. IGF2BP1-IN-1 Chemical Structure
  23. GC18093 Insulin (human) recombinant expressed in yeast

    Endogenous insulin receptor agonist

     Insulin (human) recombinant expressed in yeast Chemical Structure
  24. GC67998 Insulin degludec Insulin degludec Chemical Structure
  25. GC74561 Insulin efsitora alfa

    LY-3209590

     Insulin efsitora alfa (LY-3209590) is a selective agonist of insulin receptor (IR). Insulin efsitora alfa Chemical Structure
  26. GC69283 Insulin glargine

    Insulin glargine is a long-acting insulin analogue. It can be used for researching diabetes.

     Insulin glargine Chemical Structure
  27. GC70310 Insulin glulisine Insulin glulisine (HMR 1964) is a rapid-acting insulin analogue, it mimics the pharmacokinetic and pharmacodynamic profiles of physiological human insulin. Insulin glulisine Chemical Structure
  28. GC31526 Insulin levels modulator Insulin levels modulator could be used to treat diabetes. Insulin levels modulator Chemical Structure
  29. GC31303 Insulin(cattle) (Insulin from bovine pancreas) Insulin is a hormonal protein consisting of two chains of 21 and 30 amino acids. Insulin(cattle) (Insulin from bovine pancreas) Chemical Structure
  30. GN10497 Kaempferitrin

    BRN 0073958, Grosvenorine II, Kaempferol 3,7-O-α-Dirhamnoside, Lespedin

     Kaempferitrin Chemical Structure
  31. GC10626 KU14R KU14R Chemical Structure
  32. GC14552 LDK378

    LDK 378;LDK-378;Ceritinib

     LDK378 (LDK378) is a selective, orally bioavailable, and ATP-competitive ALK tyrosine kinase inhibitor with an IC50 of 200 pM. LDK378 Chemical Structure
  33. GC17452 LDK378 dihydrochloride LDK378 dihydrochloride Chemical Structure
  34. GC15749 Linsitinib

    OSI 906; OSI-906; OSI906

     IGF1R/IR inhibitor,potent and novel Linsitinib Chemical Structure
  35. GC61516 MID-1 MID-1 is a disruptor of MG53-IRS-1 (Mitsugumin 53-insulin receptor substrate-1) interaction. MID-1 Chemical Structure
  36. GC13525 MRS 4062 triethylammonium salt P2Y4 receptor agonist MRS 4062 triethylammonium salt Chemical Structure
  37. GC15936 MSDC-0160

    Mitoglitazone; CAY10415

     mTOT-modulating insulin sensitizer MSDC-0160 Chemical Structure
  38. GC64431 MSDC-0602K

    Azemiglitazone potassium

     MSDC-0602K (Azemiglitazone potassium), a PPARγ-sparing thiazolidinedione (Ps-TZD), binds to PPARγ with the IC50 of 18.25 μM. MSDC-0602K Chemical Structure
  39. GC12712 NT157 IRS-1/2 inhibitor, inhibits IGF-1R and STAT3 signaling pathway NT157 Chemical Structure
  40. GC69599 NT219

    NT219 is an effective dual inhibitor of insulin receptor substrate 1/2 (IRS1/2) and STAT3. IRS1/2 and STAT3 are major signaling pathways regulated by various oncogenes. NT219 affects the degradation of IRS1/2 and inhibits the phosphorylation of STAT3. NT219 has potential for researching cancer diseases.

     NT219 Chemical Structure
  41. GC12963 NVP-AEW541

    AEW541

     IGF-IR inhibitor, novel, potent and selective NVP-AEW541 Chemical Structure
  42. GN10784 Rhoifolin

    Apigenin 7-O-Neohesperidoside

     Rhoifolin Chemical Structure
  43. GC61550 S961 acetate S961 acetate is an high-affinity and selective insulin receptor (IR) antagonist with IC50s of 0.048, 0.027, and 630 nM for HIR-A, HIR-B, and human insulin-like growth factor I receptor (HIGF-IR) in SPA-assay, respectively. S961 acetate Chemical Structure
  44. GC39189 S961 TFA S961 TFA is an high-affinity and selective insulin receptor (IR) antagonist with IC50s of 0.048, 0.027, and 630 nM for HIR-A, HIR-B, and human insulin-like growth factor I receptor (HIGF-IR) in SPA-assay, respectively. S961 TFA Chemical Structure
  45. GC61957 SU4984 SU4984 is a protein tyrosine kinase inhibitor, with an IC50 of 10-20 μM for fibroblast growth factor receptor 1 (FGFR1). SU4984 is also inhibits platelet-derived growth factor receptor, and insulin receptor. SU4984 can be used for the research of cancer. SU4984 Chemical Structure
  46. GC16821 TAE226(NVP-TAE226)

    TAE 226;TAE-226

     TAE226(NVP-TAE226) (TAE226) is a potent and ATP-competitive dual FAK and IGF-1R inhibitor with IC50s of 5.5 nM and 140 nM, respectively. TAE226(NVP-TAE226) Chemical Structure
  47. GC74527 Valanafusp alfa

    AGT-181; HIRMAb-IDUA

     Valanafusp alfa (AGT-181) is a chimeric monoclonal antibody that fuses human α-L-iduronidase (IDUA) and targets the human insulin receptor (HIR). Valanafusp alfa Chemical Structure

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