Insulin Receptor
Insulin receptor is a transmembrane receptor tyrosine kinase that mediates the insulin function and involved in the regulation of cell differentiation, growth and metabolism etc.
Products for Insulin Receptor
- Cat.No. Product Name Information
- GC50157 6bK Insulin degrading enzyme (IDE) inhibitor
- GC31371 AGL-2263 An inhibitor of IGF-1R
- GC64683 AVJ16 AVJ16 is a member of the insulin-like growth factor 2 mRNA-binding protein family. AVJ16 regulates protein translation by binding to the mRNAs of certain genes.
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GC17773
BMS-536924
IR/IGF-1R inhibitor
- GC16712 BMS-754807 IGF-1R/InsR inhibitor,potent and selective
- GC45789 Ceritinib-d7 An internal standard for the quantification of ceritinib
- GC62712 DA-JC4 DA-JC4 is a dual GLP-1/GIP receptor agonist and can be used for the research of neurological disease and insulin signaling pathways.
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GC14905
Demethylasterriquinone B1
An insulin receptor (IR) activator
- GA21893 Gastric Inhibitory Polypeptide (1-30) amide (porcine) Gastric Inhibitory Polypeptide (1-30) amide (porcine) is a full glucose-dependent insulinotropic polypeptide (GIP) receptor agonist with high affinity equal to native GIP(1-42).
- GA21894 Gastric Inhibitory Polypeptide (3-42) (human) Gastric Inhibitory Polypeptide (3-42) (human) acts as a glucose-dependent insulinotropic polypeptide (GIP) receptor antagonist, moderating the insulin secreting and metabolic actions of GIP in vivo.
- GC61569 GIP (1-30) amide, porcine TFA GIP (1-30) amide, porcine TFA is a full glucose-dependent insulinotropic polypeptide (GIP) receptor agonist with high affinity equal to native GIP(1-42).
- GC60175 GIP (1-30) amide,Human acetate GIP (1-30) amide,human acetate is a glucose-dependent insulinotropic polypeptide (GIP) fragment.
- GC61741 GIP, human TFA GIP, human TFA, a peptide hormone consisting of 42 amino acids, is a stimulator of glucose-dependent insulin secretion and a weak inhibitor of gastric acid secretion.
- GC12273 GSK1838705A IGF-IR/IR/ALK inhibitor, ATP-competitive
- GC14654 HNGF6A increases glucose stimulated insulin secretion and glucose metabolism
- GC13988 HNMPA cell impermeable tyrosine kinase inhibitor
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GC18093
Insulin (human) recombinant expressed in yeast
Endogenous insulin receptor agonist
- GC67998 Insulin degludec
- GC31526 Insulin levels modulator Insulin levels modulator could be used to treat diabetes.
- GC31303 Insulin(cattle) (Insulin from bovine pancreas) Insulin cattle (Insulin from bovine pancreas) is a two-chain polypeptide hormone produced in vivo in the pancreatic β cells.
- GN10497 Kaempferitrin
- GC10626 KU14R
- GC14552 LDK378 LDK378 (LDK378) is a selective, orally bioavailable, and ATP-competitive ALK tyrosine kinase inhibitor with an IC50 of 200 pM.
- GC17452 LDK378 dihydrochloride
- GC15749 Linsitinib IGF1R/IR inhibitor,potent and novel
- GC61516 MID-1 MID-1 is a disruptor of MG53-IRS-1 (Mitsugumin 53-insulin receptor substrate-1) interaction.
- GC13525 MRS 4062 triethylammonium salt P2Y4 receptor agonist
- GC15936 MSDC-0160 mTOT-modulating insulin sensitizer
- GC64431 MSDC-0602K MSDC-0602K (Azemiglitazone potassium), a PPARγ-sparing thiazolidinedione (Ps-TZD), binds to PPARγ with the IC50 of 18.25 μM.
- GC12712 NT157 IRS-1/2 inhibitor, inhibits IGF-1R and STAT3 signaling pathway
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GC69599
NT219
NT219 is an effective dual inhibitor of insulin receptor substrate 1/2 (IRS1/2) and STAT3. IRS1/2 and STAT3 are major signaling pathways regulated by various oncogenes. NT219 affects the degradation of IRS1/2 and inhibits the phosphorylation of STAT3. NT219 has potential for researching cancer diseases.
- GC12963 NVP-AEW541 IGF-IR inhibitor, novel, potent and selective
- GN10784 Rhoifolin
- GC61550 S961 acetate S961 acetate is an high-affinity and selective insulin receptor (IR) antagonist with IC50s of 0.048, 0.027, and 630 nM for HIR-A, HIR-B, and human insulin-like growth factor I receptor (HIGF-IR) in SPA-assay, respectively.
- GC39189 S961 TFA S961 TFA is an high-affinity and selective insulin receptor (IR) antagonist with IC50s of 0.048, 0.027, and 630 nM for HIR-A, HIR-B, and human insulin-like growth factor I receptor (HIGF-IR) in SPA-assay, respectively.
- GC61957 SU4984 SU4984 is a protein tyrosine kinase inhibitor, with an IC50 of 10-20 μM for fibroblast growth factor receptor 1 (FGFR1). SU4984 is also inhibits platelet-derived growth factor receptor, and insulin receptor. SU4984 can be used for the research of cancer.
- GC16821 TAE226(NVP-TAE226) TAE226(NVP-TAE226) (TAE226) is a potent and ATP-competitive dual FAK and IGF-1R inhibitor with IC50s of 5.5 nM and 140 nM, respectively.