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Home >> Signaling Pathways >> Proteases >> Endogenous Metabolite

Endogenous Metabolite

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Targets for  Endogenous Metabolite

Products for  Endogenous Metabolite

  1. Cat.No. Product Name Information
  2. GC35521 Biotin sulfone An oxidized form of biotin Biotin sulfone Chemical Structure
  3. GC38654 Bis(2-ethylhexyl) phthalate Bis(2-ethylhexyl) phthalate (Bis(2-ethylhexyl) phthalate) is an endogenous metabolite. Bis(2-ethylhexyl) phthalate Chemical Structure
  4. GC39480 Bisphenol A Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A Chemical Structure
  5. GC35541 Boldenone Undecylenate Boldenone Undecylenate Chemical Structure
  6. GC31626 Bovinic acid An isomer of linoleic acid Bovinic acid Chemical Structure
  7. GN10146 Butane diacid Butane diacid Chemical Structure
  8. GC43000 Butyryl-L-carnitine (chloride) Butyryl-L-carnitine is a butyrate ester of carnitine. Butyryl-L-carnitine (chloride) Chemical Structure
  9. GC46972 Butyryl-L-carnitine-d3 (chloride) An internal standard for the quantification of butyryl-L-carnitine Butyryl-L-carnitine-d3 (chloride) Chemical Structure
  10. GC30298 Butyrylcarnitine Butyrylcarnitine is a metabolite in plasma, acts as a biomarker to improve the diagnosis and prognosis of heart failure, and is indicative of anomalous lipid and energy metabolism. Butyrylcarnitine Chemical Structure
  11. GC62198 c-di-AMP sodium

    C-di-AMP is a STING agonist, which binds to the transmembrane protein STING, thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF.

     c-di-AMP sodium Chemical Structure
  12. GN10792 Caffeic acid Caffeic acid Chemical Structure
  13. GC16066 Calcifediol

    Major circulating form of vitamin D3

     Calcifediol Chemical Structure
  14. GC63877 Calcifediol-d3 Calcifediol-d3 is a deuterium labeled Calcifediol. Calcifediol-d3 Chemical Structure
  15. GC13852 Calcitriol Calcitriol, as the most biologically active metabolite derived from the secosteroid hormone vitamin D, the inhibition of calcitriol caused decreased effects of anticancer drugs. Calcitriol Chemical Structure
  16. GC62883 Calcium 2-hydroxy-4-(methylthio)butanoate Calcium 2-hydroxy-4-(methylthio)butanoate is an endogenous metabolite. Calcium 2-hydroxy-4-(methylthio)butanoate Chemical Structure
  17. GC15161 Calcium D-Panthotenate Calcium D-Panthotenate (Vitamin B5 calcium salt), a vitamin, can reduce the patulin content of the apple juice. Calcium D-Panthotenate Chemical Structure
  18. GC11242 Calcium Gluceptate Calcium Gluceptate is an endogenous metabolite. Calcium Gluceptate Chemical Structure
  19. GC62884 Calcium L-Threonate Calcium L-Threonate is an anti-osteoporosis agent, and widely used as a calcium supplement. Calcium L-Threonate Chemical Structure
  20. GC66167 Calcium Phytate Calcium Phytate is found in food and is significant for human nutrition. Calcium Phytate Chemical Structure
  21. GC60672 Carveol A monoterpene alcohol with nematocidal activity Carveol Chemical Structure
  22. GC19572 Catechol Catechol Chemical Structure
  23. GC16449 Cellobiose Cellobiose is an endogenous metabolite. Cellobiose Chemical Structure
  24. GC50060 Cerestat Cerestat (Cerestat) is a non-competitive NMDA receptor antagonist with neuroprotective effect. Cerestat Chemical Structure
  25. GC62241 cGAMP disodium cGAMP (Cyclic GMP-AMPP) disodium functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. cGAMP disodium Chemical Structure
  26. GC17985 Chenodeoxycholic Acid nuclear receptors(FXR) activator Chenodeoxycholic Acid Chemical Structure
  27. GC48595 Chenodeoxycholic Acid MaxSpec® Standard A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications Chenodeoxycholic Acid MaxSpec® Standard Chemical Structure
  28. GN10518 Chitosamine hydrochloride Chitosamine hydrochloride Chemical Structure
  29. GC31590 Cholestenone A cholesterol metabolite Cholestenone Chemical Structure
  30. GC17398 Cholesterol

    Major sterol in mammals

     Cholesterol Chemical Structure
  31. GC62896 Cholesterol glucuronide Cholesterol glucuronide is an endogenous metabolite of lipid generated in the liver by UDP glucuonyltransferase. Cholesterol glucuronide Chemical Structure
  32. GC43251 Cholesterol Sulfate (sodium salt) Cholesterol Sulfate (sodium salt) is an important regulatory molecule. Cholesterol Sulfate (sodium salt) Chemical Structure
  33. GC18224 Cholesterol α-Linolenate

    Cholesterol α-linolenate is a cholesterol ester found in fatty streaks and atherosclerotic plaques isolated from human aorta.

     Cholesterol α-Linolenate Chemical Structure
  34. GC63843 Cholesterol-13C3 Cholesterol-13C3 Chemical Structure
  35. GC64334 Cholesterol-13C5 Cholesterol-13C5 Chemical Structure
  36. GC38574 Cholesteryl arachidonate Cholesteryl arachidonate is an endogenous metabolite. Cholesteryl arachidonate Chemical Structure
  37. GC31401 Cholesteryl behenate (Cholesteryl docosanoate) Cholesteryl behenate (Cholesteryl docosanoate) is a cholesterol ester associated with the neutral core of low density lipoprotein Receptor-LDL complexes are taken up by lysosomes and hydrolyzed to release cholesterol from the esters. Cholesteryl behenate (Cholesteryl docosanoate) Chemical Structure
  38. GC43257 Cholesteryl Eicosapentaenoate Cholesteryl Eicosapentaenoate is an endogenous metabolite. Cholesteryl Eicosapentaenoate Chemical Structure
  39. GC31636 Cholesteryl linoleate A cholesterol ester Cholesteryl linoleate Chemical Structure
  40. GC43261 Cholesteryl Myristate Cholesteryl Myristate is a natural steroid present in traditional Chinese medicine. Cholesteryl Myristate binds to several ion channels such as the nicotinic acetylcholine receptor, GABAA receptor, and the inward-rectifier potassium ion channel. Cholesteryl Myristate Chemical Structure
  41. GC30278 Cholesteryl oleate

    Cholesteryl oleate is an esterified form of Cholesterol.

     Cholesteryl oleate Chemical Structure
  42. GC32037 Cholesteryl palmitate A cholesterol ester Cholesteryl palmitate Chemical Structure
  43. GN10623 Cholic acid Cholic acid Chemical Structure
  44. GC39670 Cholic acid sodium Cholic acid sodium is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. Cholic acid sodium Chemical Structure
  45. GC68375 Cholic acid-13C Cholic acid-13C Chemical Structure
  46. GC66372 Cholic acid-d5 Cholic acid-d5 is the deuterium labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid-d5 Chemical Structure
  47. GN10342 Chondroitin sulfate

    Chondroitin sulfate, one of five classes of glycosaminoglycans, has been widely used in the treatment of osteoarthritis.

     Chondroitin sulfate Chemical Structure
  48. GN10190 Cinnamic acid

    trans-Cinnamic acid is a natural antimicrobial, with minimal inhibitory concentration (MIC) of 250 μg/mL against fish pathogen A.

     Cinnamic acid Chemical Structure
  49. GC65528 Cinnamic acid-d6 Cinnamic acid-d6 (3-Phenylacrylic acid-d6) is the deuterium labeled Cinnamic acid. Cinnamic acid has potential use in cancer intervention, with IC50s of 1-4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells. Cinnamic acid-d6 Chemical Structure
  50. GC39533 Cinnamoylglycine Cinnamoylglycine is a glycine conjugate of cinnamic acid and a urinary metabolite in human. Cinnamoylglycine Chemical Structure
  51. GC41586 cis-Petroselinic Acid cis-Petroselinic Acid, a positional isomer of oleic acid, is isolated from the vegetable oil of Coriandrum sativum fruits. cis-Petroselinic Acid Chemical Structure
  52. GC38205 cis-​9,​10-​Epoxystearic acid cis-9,10-Epoxystearic acid (cis-9,10-Epoxyoctadecanoic acid) is an endogenous constituent in human blood and urine. cis-​9,​10-​Epoxystearic acid Chemical Structure
  53. GC35703 Citicoline Citicoline (Cytidine diphosphate-choline) is an intermediate in the synthesis of phosphatidylcholine, a component of cell membranes. Citicoline Chemical Structure
  54. GC31186 Citicoline sodium salt Citicoline sodium salt salt is an intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes and also exerts neuroprotective effects. Citicoline sodium salt Chemical Structure
  55. GC30598 Citraconic acid

    Citraconic acid belongs to the class of organic compounds known as methyl-branched fatty acids.

     Citraconic acid Chemical Structure
  56. GC14203 Citric acid

    Commonly used laboratory reagent

     Citric acid Chemical Structure
  57. GC43296 Coenzyme B12 Coenzyme B12 (Coenzyme B12;Cobamamide;AdoCbl) is an active form of Vitamin B12 which is a cofactor for methylmalonyl CoA mutase[1]In Vitro: Coenzyme B12 serves as the cofactor for a group of enzymes that catalyze unusual rearrangement or elimination reactions. Coenzyme B12 Chemical Structure
  58. GC60720 Coenzyme FO Coenzyme FO, a deazaflavin chromophore, acts as an important hydride acceptor/donor in the central methanogenic pathway. Coenzyme FO Chemical Structure
  59. GN10668 Coenzyme Q10 Coenzyme Q10 Chemical Structure
  60. GC32470 Coenzyme Q9 (Ubiquinone Q9) Coenzyme Q9 (Ubiquinone Q9) (Ubiquinone Q9), the major form of ubiquinone in rodents, is an amphipathic molecular component of the electron transport chain that functions as an endogenous antioxidant. Coenzyme Q9 (Ubiquinone Q9) Chemical Structure
  61. GC39702 Copper tripeptide Copper tripeptide (GHK-Cu) is a tripeptide. Copper tripeptide Chemical Structure
  62. GC30166 Coproporphyrin III (Zincphyrin) Coproporphyrin III (Zincphyrin) (Zincphyrin) is a naturally occurring porphyrin derivative that is mainly found in urine. Coproporphyrin III (Zincphyrin) Chemical Structure
  63. GC12327 Corticosterone Corticosterone (17 deoxycortisol) is a glucocorticoid with oral activity and produced by adrenal cortex, which plays an important role in regulating the neuronal function of limbic system (including hippocampus, prefrontal cortex and amygdala). Corticosterone Chemical Structure
  64. GC62906 Cortisol sulfate

    Cortisol sulfate (Cortisol 21-sulfate) is a metabolite of Cortisol.

     Cortisol sulfate Chemical Structure
  65. GC65197 Cortisol sulfate sodium Cortisol sulfate sodium (Cortisol 21-sulfate) is a metabolite of Cortisol. Cortisol sulfate sodium Chemical Structure
  66. GC33839 Cortisone (17-Hydroxy-11-dehydrocorticosterone) Cortisone (17-Hydroxy-11-dehydrocorticosterone) Chemical Structure
  67. GC16772 Cortisone acetate Glucocorticoid receptor agonist Cortisone acetate Chemical Structure
  68. GC39363 Cortodoxone Cortodoxone is a glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone). Cortodoxone Chemical Structure
  69. GC39836 Coumaran Coumaran (2,3-Dihydrobenzofuran) is an acetylcholinesterase (AChE) inhibitor isolated from leaves of L. Coumaran Chemical Structure
  70. GC33777 Creatine Creatine, an endogenous amino acid derivative, plays an important role in cellular energy, especially in muscle and brain. Creatine Chemical Structure
  71. GC43323 Creatine Phosphate (potassium salt) Creatine Phosphate (potassium salt), primarily found in the skeletal muscles of vertebrates and one of organic compounds known as alpha amino acids and derivatives, is a substrate for the determination of creatine kinase and used to regenerate ATP during skeletal muscle contraction. Creatine Phosphate (potassium salt) Chemical Structure
  72. GC11872 Creatinine Break-down product of creatine phosphate in muscle Creatinine Chemical Structure
  73. GC39366 Creatinine-D3 An internal standard for the quantification of creatinine Creatinine-D3 Chemical Structure
  74. GC60728 Creosol Creosol Chemical Structure
  75. GC35752 CS-722 Free base CS-722 Free base is a synthesized centrally acting muscle relaxant, and has a muscle relaxant activity and depressant effectson the spinal reflex. CS-722 Free base Chemical Structure
  76. GC38235 Cuminaldehyde Cuminaldehyde is the major component of Cuminum cyminum, a natural aldehyde with inhibitory effect on alpha-synuclein fibrillation and cytotoxicity. Cuminaldehyde shows anticancer activity. Cuminaldehyde Chemical Structure
  77. GC62179 Cyclic ADP-ribose Cyclic ADP-ribose (cADPR) is a potent second messenger for calcium mobilization that is synthesized from NAD+ by an ADP-ribosyl cyclase. Cyclic ADP-ribose Chemical Structure
  78. GC61792 Cyclic ADP-ribose ammonium Cyclic ADP-ribose ammonium Chemical Structure
  79. GC19626 Cyclic AMP A second messenger Cyclic AMP Chemical Structure
  80. GC62372 Cyclic-di-GMP sodium Cyclic-di-GMP sodium is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP sodium has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP sodium can be used in cancer research. Cyclic-di-GMP sodium Chemical Structure
  81. GA21297 Cyclo(-Ala-Gly) Cyclo(-Ala-Gly) Chemical Structure
  82. GC30806 Cyclo(his-pro) (Cyclo(histidyl-proline)) Cyclo(his-pro) (Cyclo(histidyl-proline)) (Cyclo(histidyl-proline)) is an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone. Cyclo(his-pro) (Cyclo(histidyl-proline)) Chemical Structure
  83. GC38761 Cyclo(his-pro) TFA Cyclo(his-pro) TFA (Cyclo(histidyl-proline) TFA) is an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone. Cyclo(his-pro) TFA Chemical Structure
  84. GC60734 Cyclohexaneacetic acid Cyclohexaneacetic acid is an endogenous metabolite. Cyclohexaneacetic acid Chemical Structure
  85. GC13441 Cyclopamine Hedgehog (Hh) signaling Inhibitor Cyclopamine Chemical Structure
  86. GC33779 Cysteamine (β-Mercaptoethylamine) Cysteamine (β-Mercaptoethylamine) Chemical Structure
  87. GC13502 Cysteamine HCl Cysteamine HCl (2-Aminoethanethiol hydrochloride) is an orally active agent for the treatment of nephropathic cystinosis and an antioxidant. Cysteamine HCl Chemical Structure
  88. GC61940 Cysteinylglycine TFA Cysteinylglycine TFA is an endogenous metabolite and used in disease diagnosis. Cysteinylglycine TFA Chemical Structure
  89. GC13729 Cytidine pyrimidine nucleoside Cytidine Chemical Structure
  90. GC43355 Cytidine 5'-triphosphate (sodium salt) Cytidine 5'-triphosphate (sodium salt) is an endogenous metabolite. Cytidine 5'-triphosphate (sodium salt) Chemical Structure
  91. GC33594 Cytosine Cytosine is one of the four main bases found in DNA and RNA. Cytosine Chemical Structure
  92. GC30620 D(+)-Raffinose pentahydrate (D-Raffinose pentahydrate) D(+)-Raffinose pentahydrate (D-Raffinose pentahydrate) (D-Raffinose pentahydrate) is a trisaccharide composed of galactose, glucose, and fructose that occurs naturally in a variety of vegetables and grains. D(+)-Raffinose pentahydrate (D-Raffinose pentahydrate) Chemical Structure
  93. GA21410 D-α-Hydroxyisocaproic acid D-α-Hydroxyisocaproic acid is an amino acid metabolite. D-α-Hydroxyisocaproic acid Chemical Structure
  94. GC39652 D-α-Tocopherol acetate D-α-Tocopherol acetate (D-Vitamin E acetate) can be hydrolyzed to d-alpha-tocopherol (VE) and absorbed in the small intestine. D-α-Tocopherol acetate Chemical Structure
  95. GC38691 D-(+)-Cellobiose A disaccharide D-(+)-Cellobiose Chemical Structure
  96. GC33606 D-(+)-Glucono-1,5-lactone (Gluconic acid lactone) D-(+)-Glucono-1,5-lactone (Gluconic acid lactone) is a polyhydroxy (PHA) that is capable of metal chelating, moisturizing and antioxidant activity. D-(+)-Glucono-1,5-lactone (Gluconic acid lactone) Chemical Structure
  97. GC43367 D-(+)-Glucose-13C6 D-(+)-Glucose-13C6 is intended for use as an internal standard for the quantification of D-(+)-glucose by GC- or LC-MS. D-(+)-Glucose-13C6 Chemical Structure
  98. GC35793 D-(+)-Phenyllactic acid D-(+)-Phenyllactic acid is an anti-bacterial agent, excreted by Geotrichum candidum, inhibits a range of Gram-positive from humans and foodstuffs and Gram-negative bacteria found in humans. D-(+)-Phenyllactic acid Chemical Structure
  99. GC35794 D-(-)-Lactic acid D-(-)-Lactic acid Chemical Structure
  100. GC62920 D-(-)-Lactic acid sodium D-(-)-Lactic acid ((R)-2-Hydroxypropionic acid ) sodium is an endogenous metabolite. D-(-)-Lactic acid sodium Chemical Structure
  101. GC65896 D-Alanine-d4 D-Alanine-d4 ((R)-Alanine-d4) is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR. D-Alanine-d4 Chemical Structure

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