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Home >> Signaling Pathways >> Proteases >> Endogenous Metabolite

Endogenous Metabolite

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Targets for  Endogenous Metabolite

Products for  Endogenous Metabolite

  1. Cat.No. Product Name Information
  2. GC60784 DL-Tryptophan A racemic mixture of D- and L-tryptophan DL-Tryptophan Chemical Structure
  3. GC30765 Docosahexaenoic Acid (DHA) Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. Docosahexaenoic Acid (DHA) Chemical Structure
  4. GC31606 Docosanoic acid A long-chain saturated fatty acid Docosanoic acid Chemical Structure
  5. GC31637 Docosapentaenoic acid 22n-3

    A component of phospholipids found in all animal cell membranes

     Docosapentaenoic acid 22n-3 Chemical Structure
  6. GC32578 Docosatrienoic Acid (cis-13,16,19-docosatrienoic acid) Docosatrienoic acid is a rare ω-3 fatty acid; inhibits LTB4 binding to pig neutrophil membranes with an Ki of 5 μM. Docosatrienoic Acid (cis-13,16,19-docosatrienoic acid) Chemical Structure
  7. GC30632 Dodecanedioic acid Dodecanedioic acid (C12) is a dicarboxylic acid with a metabolic pathway intermediate to those of lipids and carbohydrates. Dodecanedioic acid Chemical Structure
  8. GC31423 Dodecanoylcarnitine Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease. Dodecanoylcarnitine Chemical Structure
  9. GC33629 DPPC (129Y83) DPPC (129Y83) (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers. DPPC (129Y83) Chemical Structure
  10. GC33660 Dulcite (Dulcitol) Dulcite (Dulcitol) is a sugar alcohol with a slightly sweet taste which is a metabolic breakdown product of galactose. Dulcite (Dulcitol) Chemical Structure
  11. GC63352 Ebaresdax Ebaresdax can inhibit peroxynitrite oxidation derived by SIN-1 and peroxynitrite mediated Cytotoxicity with IC50s?of 3.7±0.80 and 0.13±0.02 uM, respectively. Ebaresdax Chemical Structure
  12. GC30726 Eicosadienoic acid An uncommon, naturally occurring PUFA Eicosadienoic acid Chemical Structure
  13. GC11344 Eicosapentaenoic Acid EPA，omega-3 fatty acid Eicosapentaenoic Acid Chemical Structure
  14. GC33773 Elaidic acid A trans fatty acid Elaidic acid Chemical Structure
  15. GC13955 Enoxolone major component of licorice Enoxolone Chemical Structure
  16. GC18105 Enterostatin Enterostatin, human, mouse, rat is a pentapeptide that reduces fat intake. Enterostatin Chemical Structure
  17. GC62954 Enterostatin(human,mouse,rat) TFA Enterostatin (human,mouse,rat) TFA is a pentapeptide mainly formed in the intestine by the cleavage of secreted pancreatic procolipase. Enterostatin(human,mouse,rat) TFA Chemical Structure
  18. GC13072 Epiandrosterone steroid hormone with weak androgenic activity Epiandrosterone Chemical Structure
  19. GC33628 Epipregnanolone A neurosteroid and an active metabolite of pregnenolone Epipregnanolone Chemical Structure
  20. GC64195 Epsilon-(gamma-glutamyl)-lysine TFA Epsilon-(gamma-glutamyl)-lysine (H-Glu(H-Lys-OH)-OH) TFA is an N(6)-acyl-L-lysine derivative. Epsilon-(gamma-glutamyl)-lysine TFA Chemical Structure
  21. GC16292 Equol non-steroidal estrogen Equol Chemical Structure
  22. GC13804 Ercalcidiol A metabolite of vitamin D2 Ercalcidiol Chemical Structure
  23. GC63319 Ercalcidiol-d3 Ercalcidiol-d3 (25-hydroxy Vitamin D2-d3) is the deuterium labeled Ercalcidiol. Ercalcidiol-d3 Chemical Structure
  24. GN10349 Ergosterol Ergosterol Chemical Structure
  25. GN10470 Eriodictyol Eriodictyol Chemical Structure
  26. GC18075 Erythritol Erythritol is a sugar alcohol that occurs naturally in a variety of foods (e. Erythritol Chemical Structure
  27. GC10559 Erythrodiol

    Erythrodiol is a natural triterpenoid produced in olives

     Erythrodiol Chemical Structure
  28. GC13161 Escitalopram Serotonin reuptake inhibitor Escitalopram Chemical Structure
  29. GC19478 Estetrol

    An estrogen steroid hormone

     Estetrol Chemical Structure
  30. GC12182 Estriol Estrogen receptor antagonist Estriol Chemical Structure
  31. GC62961 Estriol 3-glucuronide Estriol-3-glucuronide exists in amniotic fluid during normal pregnancy and occurs naturally in urine. Estriol 3-glucuronide Chemical Structure
  32. GC14385 Estrone Estrogenic hormone Estrone Chemical Structure
  33. GC39617 Estrone sulfate potassium Estrone sulfate potassium is a natural endogenous steroid and is an estrogen ester and conjugate. Estrone sulfate potassium Chemical Structure
  34. GC12148 Ethinyl Estradiol Ethinyl Estradiol (17α-Ethynylestradiol;Ethynylestradiol) is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills. Ethinyl Estradiol Chemical Structure
  35. GC60819 Ethoxyacetic acid Ethoxyacetic acid Chemical Structure
  36. GC38593 Ethyl glucuronide Ethyl glucuronide is an endogenous metabolite. Ethyl glucuronide Chemical Structure
  37. GC62962 Ethyl nonanoate Ethyl nonanoate is a rich ester in spirits and its presence is commonly related to the pleasant fruity bouquet of alcoholic beverages. Ethyl nonanoate Chemical Structure
  38. GC33748 Ethylmalonic acid Ethylmalonic acid is non-carcinogenic potentially toxic and associated with anorexia nervosa and malonyl-CoA decarboxylase deficiency. Ethylmalonic acid Chemical Structure
  39. GC38638 Euphol

    Euphol is a tetracyclic triterpene alcohol isolated from the sap of Euphorbia tirucalli with anti-mutagenic, anti-inflammatory and immunomodulatory effects, orally active.

     Euphol Chemical Structure
  40. GC60160 FAPy-adenine FAPy-adenine is an oxidized DNA base. FAPy-adenine Chemical Structure
  41. GC32387 Farnesol Farnesol is a sesquiterpene alcohol that modulates cell-to-cell communication in Candida albicans, and has the activity in inhibiting bacteria. Farnesol Chemical Structure
  42. GC13392 Flavin adenine dinucleotide


    Flavin adenine dinucleotide Chemical Structure
  43. GC11941 Flavin adenine dinucleotide disodium Flavin adenine dinucleotide (FAD) disodium salt is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism. Flavin adenine dinucleotide disodium Chemical Structure
  44. GC19704 Flavone A polyphenolic flavonoid Flavone Chemical Structure
  45. GC38285 Flavonol Flavonol is an endogenous metabolite. Flavonol Chemical Structure
  46. GC65145 Fmoc-L-Lys (Boc)-OH-15N2 Fmoc-L-Lys (Boc)-OH-15N2 is a 15N-labeled Xanthine. Fmoc-L-Lys (Boc)-OH-15N2 Chemical Structure
  47. GN10306 Folic acid Folic acid Chemical Structure
  48. GC63952 Folic Acid-d2 Folic Acid-d2 is the deuterium labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis. Folic Acid-d2 Chemical Structure
  49. GC14331 Folinic acid NULL Folinic acid Chemical Structure
  50. GA10913 For-Met-OH For-Met-OH Chemical Structure
  51. GC34052 Fosfructose (Diphosphofructose) Fosfructose (Diphosphofructose) (Diphosphofructose;Esafosfan;FDP) is a cytoprotective natural sugar phosphate for the potential treatment of cardiovascular ischemia, sickle cell anemia and asthma. Fosfructose (Diphosphofructose) Chemical Structure
  52. GC34040 Fosfructose trisodium (Diphosphofructose (trisodium)) Fosfructose trisodium (Diphosphofructose (trisodium)) (Diphosphofructose trisodium;Esafosfan trisodium;FDP trisodium) is a cytoprotective natural sugar phosphate for the potential treatment of cardiovascular ischemia, sickle cell anemia and asthma. Fosfructose trisodium (Diphosphofructose (trisodium)) Chemical Structure
  53. GC60170 Fructosyl-lysine Fructosyl-lysine (Fructoselysine) is an amadori glycation product from the reaction of glucose and lysine by the Maillard reaction. Fructosyl-lysine Chemical Structure
  54. GC60859 Fructosyl-lysine dihydrochloride Fructosyl-lysine (Fructoselysine) dihydrochloride is an amadori glycation product from the reaction of glucose and lysine by the Maillard reaction. Fructosyl-lysine dihydrochloride Chemical Structure
  55. GC10456 Fucosterol

    Fucosterol is a plant sterol found in algae

     Fucosterol Chemical Structure
  56. GN10540 Fumalic acid

    A phenol with diverse biological activities.Natural product, extracted from ligusticum chuanxiong.

     Fumalic acid Chemical Structure
  57. GC30449 Fumaric acid Fumaric acid, associated with fumarase deficiency, is identified as an oncometabolite or an endogenous, cancer causing metabolite. Fumaric acid Chemical Structure
  58. GC30337 Galactose 1-phosphate

    Galactose 1-phosphate is an intermediate in the galactose metabolism and nucleotide sugars.

     Galactose 1-phosphate Chemical Structure
  59. GC31493 Galactose 1-phosphate Potassium salt Galactose 1-phosphate Potassium salt is is an intermediate in the galactose metabolism and nucleotide sugars. Galactose 1-phosphate Potassium salt Chemical Structure
  60. GC61436 Gallic acid hydrate Gallic acid (3,4,5-Trihydroxybenzoic acid) hydrate is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2). Gallic acid hydrate Chemical Structure
  61. GC66838 Gamibetal Gamibetal is the gamma-amino-beta-hydroxybutyric acid. Gamibetal has the potential for the research of epilepsy. Gamibetal Chemical Structure
  62. GC17170 gamma-Glu-Cys gamma-Glu-Cys (γ-Glutamylcysteine), a dipeptide containing cysteine and glutamic acid, is a precursor to glutathione (GSH). gamma-Glu-Cys Chemical Structure
  63. GC36151 Glucagon-Like Peptide (GLP) II, human Glucagon-Like Peptide (GLP) II, human is a 33-amino acid peptide derived from the C-terminal of proglucagon and mainly produced by the intestinal L cells. Glucagon-Like Peptide (GLP) II, human Chemical Structure
  64. GC15502 Gluconate sodium Gluconate sodium (D-Gluconic acid sodium salt) is a corrosion and scale inhibitor of ordinary steel in simulated cooling water. Gluconate sodium Chemical Structure
  65. GC30263 Glucosamine (D-Glucosamine) Glucosamine (D-Glucosamine) (D-Glucosamine (D-Glucosamine)) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine (D-Glucosamine) Chemical Structure
  66. GN10669 Glucosamine sulfate Glucosamine sulfate Chemical Structure
  67. GC33814 Glutaric acid Glutaric acid, C5 dicarboxylic acid, is an intermediate during the catabolic pathways of lysine and tryptophan. Glutaric acid Chemical Structure
  68. GC64471 Glutaric acid-d6 Glutaric acid-d6 Chemical Structure
  69. GC31609 Glutarylcarnitine Glutarylcarnitine is the diagnostic metabolite for malonic aciduria and glutaric aciduria type I monitored in most tandem mass spectrometry newborn screening programmes. Glutarylcarnitine Chemical Structure
  70. GC31353 Glutathione oxidized (L-Glutathione oxidized) Glutathione oxidized (L-Glutathione oxidized) (GSSG) is produced by the oxidation of glutathione. Glutathione oxidized (L-Glutathione oxidized) Chemical Structure
  71. GC36158 Glycerol Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis. Glycerol Chemical Structure
  72. GC36159 Glycerol 3-phosphate Glycerol 3-phosphate is produced by cytosolic glycerol 3-phosphate dehydrogenase pathway through the reduction of dihydroxyacetone phosphate using NADH formed during glycolysis. Glycerol 3-phosphate Chemical Structure
  73. GC38284 Glycerophosphoric acid disodium salt hydrate Glycerophosphoric acid disodium salt hydrate, an endogenous metabolite, is a phosphatase inhibitor. Glycerophosphoric acid disodium salt hydrate Chemical Structure
  74. GC68215 Glycine-1-13C Glycine-1-13C Chemical Structure
  75. GC64245 Glycine-13C2 Glycine-13C2 Chemical Structure
  76. GC64249 Glycine-15N Glycine-15N Chemical Structure
  77. GC64845 Glycine-d2 Glycine-d2 is the deuterium labeled Glycine. Glycine-d2 Chemical Structure
  78. GC34092 Glycochenodeoxycholic acid (Chenodeoxycholylglycine) Glycochenodeoxycholic acid (Chenodeoxycholylglycine) (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) (Chenodeoxycholylglycine) induces hepatocyte apoptosis. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) Chemical Structure
  79. GC43776 Glycochenodeoxycholic Acid (sodium salt)

    Glycochenodeoxycholic acid (GCDCA) is a glycine-conjugated form of the primary bile acid chenodeoxycholic acid.

     Glycochenodeoxycholic Acid (sodium salt) Chemical Structure
  80. GC34134 Glycocholic acid A glycine-conjugated form of cholic acid Glycocholic acid Chemical Structure
  81. GC62993 Glycocholic acid hydrate Glycocholic acid hydrate is an endogenous metabolite. Glycocholic acid hydrate Chemical Structure
  82. GC67835 Glycocholic acid sodium Glycocholic acid sodium Chemical Structure
  83. GC31576 Glycodeoxycholate Sodium (Sodium glycyldeoxycholate) Glycodeoxycholate Sodium (Sodium glycyldeoxycholate) is a bile salt. Glycodeoxycholate Sodium (Sodium glycyldeoxycholate) Chemical Structure
  84. GC38644 Glycodeoxycholic Acid A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications Glycodeoxycholic Acid Chemical Structure
  85. GC33804 Glycogen Glycogen is a glycolytic intermediates and high-energy phosphates that can serve as a form of energy storage in humans, animals, fungi, and bacteria. Glycogen Chemical Structure
  86. GC40913 Glycohyodeoxycholic Acid Glycohyodeoxycholic acid is a major metabolite of the secondary bile acid hyodeoxycholic acid in humans. Glycohyodeoxycholic Acid Chemical Structure
  87. GC31549 Glycolic acid Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour. Glycolic acid Chemical Structure
  88. GC68415 Glycolic acid-d2 Glycolic acid-d2 Chemical Structure
  89. GC33687 Glycoursodeoxycholic acid (Ursodeoxycholylglycine) Glycoursodeoxycholic acid (Ursodeoxycholylglycine), a acyl glycine and a bile acid-glycine conjugate, is a metabolite of ursodeoxycholic acid. Glycoursodeoxycholic acid (Ursodeoxycholylglycine) Chemical Structure
  90. GC31524 Glycylglycine

    Glycylglycine is the simplest of all peptides and could function as a gamma-glutamyl acceptor.

     Glycylglycine Chemical Structure
  91. GC15388 Glyoxylic acid Glyoxalic acid (NSC 27785) is an organic compound that is both an aldehyde and a carboxylic acid. Glyoxylic acid Chemical Structure
  92. GC38440 Guaiazulene Guaiazulene is present in several essential oils of medicinal and aromatic plants, with antioxidant activity. Guaiazulene Chemical Structure
  93. GC31397 Guanidine hydrochloride (Guanidinium chloride) Guanidine hydrochloride (Guanidinium chloride) Chemical Structure
  94. GC16949 Guanine A purine base Guanine Chemical Structure
  95. GC30732 Guanosine (DL-Guanosine) Guanosine (DL-Guanosine) (DL-Guanosine (DL-Guanosine)) is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine (DL-Guanosine) Chemical Structure
  96. GC66869 Guanosine 5'-diphosphate sodium Guanosine 5'-diphosphate (GDP) sodium is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K+ channel. Guanosine 5'-diphosphate sodium is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate sodium can be used in the research of inflammation, such as anemia of inflammation (AI). Guanosine 5'-diphosphate sodium Chemical Structure
  97. GC30715 Guanosine 5'-diphosphate Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K+ channel. Guanosine 5'-diphosphate Chemical Structure
  98. GC34609 Guanosine 5'-diphosphate disodium salt Guanosine 5'-diphosphate (GDP) disodium salt is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K+ channel. Guanosine 5'-diphosphate disodium salt Chemical Structure
  99. GC61932 Guanosine-5'-triphosphate disodium salt An energy substrate for protein synthesis and gluconeogenesis Guanosine-5'-triphosphate disodium salt Chemical Structure
  100. GC31562 Guanylic acid (5'-GMP) Guanylic acid (5'-GMP) (5'-GMP) is involved in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and the 2-hydroxyglutric aciduria pathway. Guanylic acid (5'-GMP) Chemical Structure
  101. GC61604 Guanylin(human) TFA Guanylin(human) TFA, a 15-amino acid peptide, is an endogenous intestinal guanylate cyclase activator. Guanylin(human) TFA Chemical Structure

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