HIV
HIV (human immunodeficiency virus) is a lentivirus that infect immune system. It cause immune system failure and lead to AIDS (acquired immnudeficiency syndrome).
Products for HIV
- Cat.No. Product Name Information
- GC14269 Cobicistat (GS-9350) An inhibitor of CYP3A
- GC35731 Corydine Corydine is a naturally occurring alkaloid which can be extracted from plants such as Croton echinocarpus leaves.
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GC25306
CQ31
CQ31, a small molecule, selectively activates caspase activation and recruitment domain-containing 8 (CARD8).
- GC64068 Cyclotriazadisulfonamide Cyclotriazadisulfonamide (CADA) is a specific CD4-targeted HIV entry inhibitors.
- GC35790 Cys-TAT(47-57) Cys-TAT(47-57) (Cys-[HIV-Tat (47-57)]) is an arginine rich cell penetrating peptide derived from the HIV-1 transactivating protein.
- GC33982 D77 D77 is anti-HIV-1 inhibitor targeting the interaction between integrase and cellular LEDGF/p75. D77 inhibits HIV-1(IIIB) replication by EC50 value of 23.8 μg/ml in MT-4 cell (5.03 μg/ml for C8166 cells).
- GC14452 Dapivirine (TMC120) Dapivirine (TMC120) (TMC120), the prototype of diarylpyrimidines (DAPY), is an orally active and nonnucleoside reverse transcriptase inhibitor (NRTI).
- GC17040 DAPTA Chemokine receptor 5 (CCR5) antagonist
- GC48359 DAPTA (acetate) A CCR5 receptor antagonist
- GC16602 Darunavir An HIV-1 protease inhibitor
- GC17942 Darunavir Ethanolate nonpeptidic HIV protease inhibitor
- GC47173 Darunavir-d9 An internal standard for the quantification of darunavir
- GC35823 DDX3-IN-1 DDX3-IN-1 (Compound 16f) is a DEAD-box polypeptide 3 (DDX3) inhibitor with CC50s of 50 and 36 μM for HIV and HCV, respectively.
- GC64391 DDX3-IN-2 DDX3-IN-2 is an active DEADbox polypeptide 3 (DDX3) inhibitor with an IC50 value of 0.3 μM.
- GC64270 Decanoyl-RVKR-CMK TFA Decanoyl-RVKR-CMK (DecRVKRcmk) TFA inhibits over-expressed gp160 processing and HIV-1 replication.
- GC35835 Delavirdine Delavirdine (U 90152) is a potent, highly specific and orally active non-nucleoside reverse transcriptase inhibitor (NNRTI).
- GC15452 Delavirdine mesylate Non-nucleoside reverse transcriptase inhibitor
- GC45650 Des(benzylpyridyl) Atazanavir A metabolite of atazanavir
- GC52038 Desthiazolylmethyl Ritonavir A ritonavir degradation product
- GC15984 Deuterated Atazanivir-D3-1 HIV-1 protease inhibitor
- GC11772 Deuterated Atazanivir-D3-2 HIV-1 protease inhibitor
- GC15050 Deuterated Atazanivir-D3-3 HIV-1 protease inhibitor
- GC10520 Dextran sulfate sodium salt (M.W 200000) Dextran sulfate sodium salt is a is a polymer of anhydroglucose with the molecular weight range of 35000-45000.
- GC38250 Dextran sulfate sodium salt (MW 16000-24000) A sulfated polysaccharide
- GC38252 Dextran sulfate sodium salt (MW 35000-45000) A sulfated polysaccharide
- GC38253 Dextran sulfate sodium salt (MW 4500-5500) A sulfated polysaccharide
- GC38251 Dextran sulfate sodium salt (MW 450000-550000) A sulfated polysaccharide
- GC15330 Didanosine Reverse transcriptase inhibitor
- GC49022 Didanosine-d2 An internal standard for the quantification of didanosine
- GC18456 Digallic Acid Digallic acid is a natural polyphenolic that can be produced by hydrolysis of gallotannins.
- GC38662 Dimercaprol Dimercaprol (2,3-Dimercapto-1-propanol) is an anti-heavy metal-poisoning drug, which exhibits anti-HIV activity.
- GC39734 Diphyllin Diphyllin is an arylnaphthalene lignan isolated from Justicia procumbens and is a potent HIV-1 inhibitor with an IC50 of 0.38 μM.
- GC32142 Ditiocarb sodium (Sodium diethyldithiocarbamate) Ditiocarb sodium (Sodium diethyldithiocarbamate) (Sodium diethyldithiocarbamate) is an accelerator of the rate of copper cementation.
- GC43498 DL-α-Lipoic Acid DL-α-Lipoic Acid is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes.
- GC49288 Dolutegravir M1 A metabolite of dolutegravir
- GC49289 Dolutegravir O-β-D-Glucuronide A metabolite of dolutegravir
- GC19126 Doravirine Doravirine is a novel non-nucleoside inhibitor of HIV-1 reverse transcriptase with potent activity against wild-type virus (95% inhibitory concentration 19 nM, 50% human serum).
- GC17567 Doxorubicin (Adriamycin) HCl Doxorubicin (Hydroxydaunorubicin) hydrochloride, a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent.
- GC33968 DPC-681 (DPH-153893) DPC-681 (DPH-153893) is a potent and selective inhibitor of HIV protease with IC90s for wild-type HIV-1 of 4 to 40 nM.
- GC17015 DRB DRB is a nucleoside analog that inhibits several carboxyl-terminal domain (CTD) kinases including casein kinase II and CDKs. DRB trigger p53-dependent apoptosis of human colon adenocarcinoma cells without inducing genotoxic stress to healthy cells.
- GC10331 Ebselen A peroxynitrite scavenger
- GC12389 Efavirenz Reverse transcriptase inhibitor
- GC62607 EFdA-TP tetraammonium EFdA-TP tetraammonium is a potent nucleoside reverse transcriptase (RT) inhibitor.
- GC62295 Elsulfavirine Elsulfavirine is a reverse transcriptase inhibitors for HIV-1 infection and is a new anti-HIV drug.
- GC14996 Elvitegravir (GS-9137) An inhibitor of HIV-1 integrase
- GC64484 Emivirine Emivirine (MKC-442) is a non-nucleoside reverse transcriptase inhibitors (NNRTIs) with Ki values of 0.20 and 0.01 μM for dTTP- and dGTP-dependent DNA or RNA polymerase activity, respectively.
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GC13653
Emtricitabine
Reverse transcriptase inhibitor
- GC43600 Emtricitabine S-oxide Emtricitabine S-oxide is a potential impurity found in commercial preparations of emtricitabine.
- GC11162 Enfuvirtide HIV fusion inhibitor
- GC38109 Enfuvirtide acetate Enfuvirtide (T20; DP178) acetate is an anti-HIV-1 fusion inhibitor peptide.
- GC40224 Epiequisetin Epiequisetin is a fungal metabolite and an epimer of equisetin.
- GC15996 Etravirine (TMC125) Etravirine (TMC125) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV.
- GC33536 Etravirine D4 (TMC-125 D4) Etravirine D4 (TMC-125 D4) (TMC-125 D4) is the deuterium labeled Etravirine.
- GC45825 Etravirine-d6 An internal standard for the quantification of etravirine
- GC38437 Fangchinoline An alkaloid with diverse biological activities
- GC14289 Fasudil (HA-1077) HCl Fasudil (HA-1077; AT877) Hydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively. Fasudil (HA-1077) HCl is also a potent Ca2+ channel antagonist and vasodilator.
- GC36033 FC131 TFA FC131 TFA is a CXCR4 antagonist, inhibits [125I]-SDF-1 binding to CXCR4, with an IC50 of 4.5 nM.
- GC43659 Feglymycin Feglymycin is a 13-amino acid peptide originally isolated from Streptomyces that has antibacterial and antiviral activities.
- GC60840 FGI-106 tetrahydrochloride FGI-106 tetrahydrochloride is a potent and broad-spectrum inhibitor with inhibitory activity against multiple viruses.
- GC16063 Flavopiridol An inhibitor of cyclin-dependent kinases
- GC16425 Flavopiridol hydrochloride CDK inhibitor, potent and selective
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GC14466
Fluorouracil (Adrucil)
A prodrug form of FdUMP
- GC63646 Formycin A Formycin A (NSC 102811), a purine nucleoside antibiotic, is a potent human immunodeficiency virus type 1 (HIV-1) inhibitor with an EC50 of 10 μM.
- GC32362 Fosamprenavir (Amprenavir phosphate) Fosamprenavir (Amprenavir phosphate) (Amprenavir phosphate;GW 433908) is a phosphate ester prodrug of the antiretroviral protease inhibitor Amprenavir, with improved solubility.
- GC11300 Fosamprenavir Calcium Salt A prodrug form of amprenavir
- GC36072 Fostemsavir Tris Fostemsavir Tris (BMS-663068 (Tris)) is the phosphonooxymethyl prodrug of BMS-626529.
- GC40849 Funalenone Funalenone is a phenalenone originally isolated from A.
- GC49229 Ganodermanontriol Ganodermanontriol, a sterol isolated from Ganoderma lucidum, induces anti-inflammatory activity in tert-butyl hydroperoxide (t-BHP)-damaged hepatic cells through the expression of HO-1. Ganodermanontriol exhibits hepatoprotective activity.
- GC33910 Gardiquimod trifluoroacetate Gardiquimod trifluoroacetate, an imidazoquinoline analog, is a TLR7/8 agonist.
- GC47398 Genistein-d4 An internal standard for the quantification of genistein
- GC36143 Glabranine Glabranine, an flavonoid, is isolated from Tephrosia s.
- GC52492 Globotriaosylceramide (hydroxy) (porcine RBC) A sphingolipid
- GC52491 Globotriaosylceramide (non-hydroxy) (porcine RBC) A sphingolipid
- GC43758 Globotriaosylceramides (hydroxy) (porcine) Globotriaosycleramides are glycosphingolipids found in mammalian cell membranes that are synthesized from lactosylceramides.
- GC43760 Globotriaosylceramides (porcine) Globotriaosycleramides are glycosphingolipids found in mammalian cell membranes that are synthesized from lactosylceramides.
- GC32210 Gomisin G Gomisin G is an ethanolic extract of the stems of Kadsura interior; exhibits potent anti-HIV activity with EC50 and therapeutic index (TI) values of 0.006 microgram/mL and 300, respectively.
- GC64233 Gomisin M2 Gomisin M2 ((+)-Gomisin M2) is a lignan isolated from the fruits of Schisandra rubriflora with anti-HIV activity (EC50 of 2.4 μM).
- GC38790 GS-6207 GS-6207 (GS-6207) is a HIV-1 capsid inhibitor.
- GC12679 GS-7340 GS-7340 (GS-7340) is an investigational oral prodrug of Tenofovir.
- GC12555 GS-9620 A TLR7 agonist
- GC14057 GSK1349572 sodiuM salt GSK1349572 sodiuM salt (S/GSK1349572 sodium) is a highly potent and orally bioavailable HIV integrase strand transfer inhibitor with an IC50 of 2.7 nM for HIV-1 integrase-catalyzed strand transfer.
- GC18484 GSK2578999A
- GC12329 GSK2838232 HIV-1 maturation inhibitor
- GC16215 GSK744 (S/GSK1265744) GSK744 (S/GSK1265744) (GSK-1265744) is a orally active and long-acting HIV integrase inhibitor and organic anion transporter 1/3 (OAT1/OAT3) inhibitor with IC50 values of 2.5 nM, 0.41 μM and 0.81 μM for HIVADA, OAT3 and OAT1, respectively.
- GC49027 Hexamethylene bisacetamide Hexamethylene bisacetamide is a tumor cell-differentiating agent.
- GC36232 HIV-1 inhibitor-3 HIV-1 inhibitor-3 is a HIV infection inhibitor extracted from patent US2018360927.
- GC68023 HIV-1 inhibitor-48
- GC65256 HIV-1 inhibitor-6 HIV-1 inhibitor-6 (compound 9), a diheteroarylamide-based compound, is a potent HIV-1 pre-mRNA alternative splicing inhibitor.
- GC65158 HIV-1 inhibitor-8 HIV-1 inhibitor-8 is an orally active, low-toxicity and potent HIV?1 non-nucleoside reverse transcriptase inhibitor (NNRTI).
- GC12998 HIV-1 integrase inhibitor
- GC36233 HIV-1 integrase inhibitor 2 HIV-1 integrase inhibitor 2 (CX05168) is a quinoline-based protein-protein interaction inhibitor of LEDGF/p75 and HIV integrase.
- GC36234 HIV-1 integrase inhibitor 3 HIV-1 integrase inhibitor 3 is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 2.7 nM.
- GC36235 HIV-1 integrase inhibitor 4 HIV-1 integrase inhibitor 4 is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 3.7 nM.
- GC32342 HIV-1 Rev 34-50 (HIV-1 rev Protein (34-50)) HIV-1 Rev 34-50 (HIV-1 rev Protein (34-50)) is a 17-aa peptide derived from the Rev-responsive element (RRE)-binding domains of Rev in HIV-1, with anti-HIV-1 activity.
- GC65134 HIV-IN-6 HIV-IN-6 is a HIV-Ⅰ viral replication inhibitor by targeting Src family kinases (SFK) that interact with Nef protein of the virus, such as Hck.
- GC16843 Hydroxyurea DNA synthesis inhibitor
- GC65034 Ibalizumab Ibalizumab (TMB-355) is a humanised IgG4 monoclonal antibody that prevents HIV cell entry by binding to CD4 receptor.
- GC18545 Ilimaquinone Ilimaquinone is a natural sesquiterpene quinone that has antimicrobial, anti-HIV, anti-mitotic, and anti-inflammatory properties.
- GC61820 IMB-301 IMB-301 is a specific HIV-1 replication inhibitor that binds to hA3G (human APOBEC3G), interrupts the hA3G-Vif interaction and inhibits Vif-mediated degradation of hA3G.
- GC36309 Indinavir Indinavir (MK-639 free base) is an orally active and selective HIV-1 protease inhibitor with a Ki of 0.54 nM for PR.