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Home >> Proteins

Proteins

Products for  Proteins

  1. Cat.No. Product Name Information
  2. GC47452 Imatinib-d3

    Genfatinib-d3

     Imatinib-d3 (STI571-d3) hydrochloride is the deuterium labeled Imatinib. Imatinib (STI571) is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity. Imatinib (STI571) works by binding close to the ATP binding site, locking it in a closed or self-inhibited conformation, therefore inhibiting the enzyme activity of the protein semicompetitively. Imatinib also is an inhibitor of SARS-CoV and MERS-CoV. Imatinib-d3 Chemical Structure
  3. GC72971 INCB3619 INCB3619 is a selective and orally active ADAM inhibitor with IC50 of 22 nM and 14 nM for ADAM10 and ADAM17, respectively. INCB3619 Chemical Structure
  4. GC48387 Inostamycin A A bacterial metabolite with anticancer activity Inostamycin A Chemical Structure
  5. GC65287 INX-SM-56 INX-SM-56 is an anti-VISTA antibody drug conjugate and can be used for targeted delivery of anti-inflammatory agents. INX-SM-56 Chemical Structure
  6. GC65286 INX-SM-6 INX-SM-6 can be used for targeted delivery of anti-inflammatory agent. INX-SM-6 Chemical Structure
  7. GC47459 Irinotecan-d10 (hydrochloride)

    Camptothecin 11-d10, CPT 11- d10, Topotecin-d10, U 101440E-d10

     An internal standard for the quantification of irinotecan Irinotecan-d10 (hydrochloride) Chemical Structure
  8. GC60940 Iron dextran Iron dextran is an injectable complex comprising ferric hydroxide and a low-molecular-weight fraction of dextran. Iron dextran is a type of intravenous iron agent specifically used for the treatment of iron deficiency anemia. Iron dextran Chemical Structure
  9. GC17108 ISO-1

    ISO1, Macrophage Migration Inhibitory Factor

     ISO-1 is a cell-permeable isoxazoline class macrophage migration inhibitory factor (MIF) antagonist (IC50=7μM). ISO-1 Chemical Structure
  10. GC25530 Iso-H7 dihydrochloride Iso-H7 dihydrochloride is an inhibitor of phosphokinase C. Iso-H7 dihydrochloride Chemical Structure
  11. GC69315 JMS-053

    JMS-053 is an effective, selective, and reversible inhibitor of PTP4A. It inhibits PTP4A1, PTP4A2, PTP4A3, CDC25B and DUSP3 with IC50 values of 29.1 nM, 48.0 nM, 34.7 nM, 92.6 nM and 207.6 nM respectively. JMS-053 can inhibit cancer cell migration and spheroid growth while reducing the growth of ovarian tumors in vivo.

     JMS-053 Chemical Structure
  12. GC69323 JUN-1111

    JUN-1111 is an irreversible selective inhibitor of Cdc25 phosphatase, with IC50 values of 0.38, 1.8, 0.66, 28 and 37 μM for Cdc25A, Cdc25B, Cdc25C, VHR and PTP1B respectively. JUN-1111 induces cell cycle arrest at G1 and G2/M phases and reduces the expression of phosphoCdk1.

     JUN-1111 Chemical Structure
  13. GC50716 K 22 An antiviral agent K 22 Chemical Structure
  14. GC47523 K-41 A fungal metabolite with antibiotic and antiparasitic activities K-41 Chemical Structure
  15. GC71069 Kallikrein 5-IN-2 Kallikrein 5-IN-2 (compound 21) is a selective Kallikrein KLK5 inhibitor (pIC50=7.1). Kallikrein 5-IN-2 Chemical Structure
  16. GC43996 KBC-007 KBC-007 is a synthetic branched chain-containing analog of α-galactosylceramide (α-GalCer). KBC-007 Chemical Structure
  17. GC92122 KBP-066 (trifluoroacetate salt) KBP-066 is a dual amylin and calcitonin (CT) receptor agonist. KBP-066 (trifluoroacetate salt) Chemical Structure
  18. GC79741 KF-52 enantiomer KF-52 enantiomer is an enantiomer of KF-52. KF-52 enantiomer Chemical Structure
  19. GC44004 Kijanimicin

    NSC 329515

     Kijanimicin is an antibiotic first isolated from the fermentation broth of A. Kijanimicin Chemical Structure
  20. GC44008 KLH45 KLH45 is an inhibitor of the phospholipase DDHD domain containing 2 (DDHD2; IC50 = 1.3 nM). KLH45 Chemical Structure
  21. GC70408 KLH45b KLH45b is an inhibitor of DDHD2 (DDHD domain containing 2). KLH45b Chemical Structure
  22. GC32452 KP-457 KP-457 is a selective inhibitor of A disintegrin and metalloproteinase 17 (ADAM17) with an IC50 of 11.1nM. KP-457 inhibits ADAM10 (IC50=748nM), MMP2 (IC50=717nM), MMP3 (IC50=9760nM), MMP7 (IC50=2200nM), MMP9 (IC50=5410nM), MMP13 (IC50=930nM), MMP14 (IC50=2140nM), and MMP17 (IC50=7100nM). KP-457 Chemical Structure
  23. GC18909 KRIBB3

    KRIBB3 is an Hsp27 and microtubule inhibitor that inhibits migration and invasion of MDA-MB-231 cells in vitro in an Hsp27-dependent manner.

     KRIBB3 Chemical Structure
  24. GC18180 KRN 7000 KRN7000[(2S,3S.4R)-l-O-(a-D-galactopyranosyl)-2-(N-hexacosanoylamino)-l,3.4-octadecanetriol] is a highly potent synthetic alpha-galactose ceramide originally isolated from an ocean sponge that is widely used in the study of tumors and autoimmune diseases due to its ability to specifically present CD1d on the cell surface and thus activate NKT cells. KRN 7000 Chemical Structure
  25. GC79388 KVD-001 KVD-001 is a potent plasma kallikrein inhibitor. KVD-001 Chemical Structure
  26. GC46015 KY 05009 A TNIK inhibitor KY 05009 Chemical Structure
  27. GC61578 L-690330 hydrate L-690330 hydrate is a competitive inhibitor of inositol monophosphatase (IMPase) with Kis of 0.27 and 0.19 μM for recombinant human and bovine IMPase, 0.30 and 0.42 μM for human and bovine frontal cortex IMPase, respectively. L-690330 hydrate Chemical Structure
  28. GC19511 L-Ascorbic Acid 2-phosphate (magnesium salt)

    AA2P, Ascorbyl PM, Phospitan C

     L-Ascorbic Acid 2-phosphate (magnesium salt) (AA2P) is a stable VC(vitamin C) derivative. L-Ascorbic Acid 2-phosphate (magnesium salt) Chemical Structure
  29. GC44084 L-Selenocystine

    Seleno-L-cystine

     L-Selenocystine is an oxidation diselenide product of selenocysteine with strong antioxidant activity. L-Selenocystine Chemical Structure
  30. GC91889 L-Tyrosine (sodium salt hydrate)

    L-4-Hydroxyphenylalanine; p-Hydroxyphenylalanine; (-)-Tyrosine; p-Tyrosine

     L-Tyrosine is a conditionally essential amino acid. L-Tyrosine (sodium salt hydrate) Chemical Structure
  31. GC74567 Labetuzumab govitecan

    IMMU 130; hMN-14-SN-38

    Labetuzumab govitecan (IMMU 130) is an Anti-CEACAM5/SN-38 antibody-drug conjugate (ADC).

     Labetuzumab govitecan Chemical Structure
  32. GC79683 LacCer (d18:1/20:0) LacCer (d18:1/20:0) is a lipid whose level is closely associated with atherosclerosis and cardiovascular diseases [1]. LacCer (d18:1/20:0) Chemical Structure
  33. GC44031 Lalistat 2 Lalistat 2 is an inhibitor of lysosomal acid lipase (LAL), with an IC50 value of 152nM. Lalistat 2 Chemical Structure
  34. GC72335 Lanadelumab Lanadelumab (SHP643) is a human IgG1 monoclonal antibody against plasma kallikrein (pKal) with an Ki value of 0.12 nM. Lanadelumab Chemical Structure
  35. GC81315 Lck-IN-5 Lck-IN-5 (example C10) is a potent and selective lymphocyte-specific protein tyrosine kinase ( LCK ) inhibitor. Lck-IN-5 Chemical Structure
  36. GC49753 LCS3 LCS3 Chemical Structure
  37. GC79169 Lepodisiran

    LY3819469

     Lepodisiran (LY3819469) is a GalNAc-conjugated small interfering RNA lipid-lowering agent. Lepodisiran Chemical Structure
  38. GC74571 Ligufalimab

    AK 117

     Ligufalimab (AK 117) is a humanized IgG4 anti-CD47 monoclonal antibody. Ligufalimab Chemical Structure
  39. GC74604 Linvoseltamab

    REGN5458

     Linvoseltamab is a bispecific antibody targeting to both BCMA (TNFRSF17) and CD3 epsilon. Linvoseltamab Chemical Structure
  40. GC92125 Liraglutide (acetate)

    NN 2211

     Liraglutide is a potent agonist of the glucagon-like peptide 1 (GLP-1) receptor and a synthetic derivative of GLP-1 (7-37) that contains a palmitic acid group. Liraglutide (acetate) Chemical Structure
  41. GC69393 Loncastuximab tesirine

    Loncastuximab tesirine-lpyl; ADCT-402

    Loncastuximab tesirine is an antibody-active molecule conjugate (ADC) that targets human cluster of differentiation 19 (CD19). Once bound to CD19 on the cell membrane, Loncastuximab tesirine is rapidly internalized, leading to cell death. Loncastuximab tesirin induces apoptosis and can be used for research on diffuse large B-cell lymphoma.

     Loncastuximab tesirine Chemical Structure
  42. GC92038 Lotiglipron (hydrochloride)

    PF-07081532

     Lotiglipron is a glucagon-like peptide 1 receptor (GLP-1R) agonist. Lotiglipron (hydrochloride) Chemical Structure
  43. GC47582 Lupulone A beta-acid Lupulone Chemical Structure
  44. GC44093 Lutein

    E 161b, Xanthophyll

     Lutein is a naturally occurring carotenoid with multiple biological activities and is widely found in green leafy vegetables, corn, and egg yolks. Lutein Chemical Structure
  45. GC79343 LY3541860 LY3541860 is a selective anti- CD19 antibody that both binds human CD19 with high affinity and selectively binds human B cells ( K d values: 76.8 pM and 94.5 nM for humans and cynomolgus monkeys, respectively). LY3541860 Chemical Structure
  46. GC64338 LYP-IN-1 LYP-IN-1 is a potent, selective and specific LYP inhibitor with a Ki and an IC50 of 110 nM and 0.259 μM, respectively. LYP-IN-1 Chemical Structure
  47. GC73595 LYP-IN-3 LYP-IN-3 (compound D34) is a selective inhibitor of Lymphoid-tyrosine phosphatase (LYP) (Ki=0.93 μM), and regulates T-cell receptor (TCR) signaling pathway in tumor progress. LYP-IN-3 Chemical Structure
  48. GC72176 Lysyl endopeptidase, Achromobacter sp Lysyl endopeptidase, Achromobacter sp (Lys-C) catalyzes carboxyl oxygen exchange reaction. Lysyl endopeptidase, Achromobacter sp Chemical Structure
  49. GC44106 Lythridine

    Sinine

     Lythridine is a biphenyl quinolizidine lactone alkaloid originally isolated from Fraxinus sinica that has antimalarial properties. Lythridine Chemical Structure
  50. GC26650 M-CSF, Mouse (CHO-expressed)

    Macrophage-Colony Stimulating Factor (M-CSF), also known as Colony Stimulating Factor-1 (CSF-1), is a hematopoietic growth factor. 

     M-CSF, Mouse (CHO-expressed) Chemical Structure
  51. GC73020 M5N36 M5N36 is a potent and selective Cdc25C inhibitor with IC50 values of 0.15, 0.19, 0.06 µM for Cdc25A, Cdc25B, Cdc25C, respectively. M5N36 Chemical Structure
  52. GC73846 MA3 aptamer sodium MA3 aptamer sodium is an 86-base long DNA aptamer targeting the mucin MUC1. MA3 aptamer sodium Chemical Structure
  53. GC49208 Maduramicin (ammonium salt)

    Antibiotic X-14868A, CL 259,971, Maduramycin, Prinicin

     Maduramicin (ammonium salt) (Maduramycin ammonium) is isolated from the actinomyceteActinomadura rubra. Maduramicin (ammonium salt) Chemical Structure
  54. GC44126 Manzamine A

    Keramamine A

     Manzamine A is a β-carboline alkaloid with diverse activities that has been found in marine sponges, including X. Manzamine A Chemical Structure
  55. GC76568 Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2

    Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2

    Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 is a fluorescently quenched peptide substrate that can be used to detect the activity of matrix metalloproteinases (MMPs) and their associated tumor necrosis factor converting enzyme (TACE) (Ex/Em=325nm/400nm).

     Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 Chemical Structure
  56. GC72202 Mca-PLAQAV-Dpa-RSSSR-NH2 TFA Mca-PLAQAV-Dpa-RSSSR-NH2 is a fluorescent peptide and as one of fluorescent substrates of TNF-α converting enzyme (TACE); ADAM17, ADAM 9 and ADAM 10. Mca-PLAQAV-Dpa-RSSSR-NH2 TFA Chemical Structure
  57. GC92036 MCL0020 (trifluoroacetate salt)

    Ac-D-2Nal-Arg-2-Nal-NH2

     MCL0020 is a melanocortin receptor 4 (MC4R) antagonist. MCL0020 (trifluoroacetate salt) Chemical Structure
  58. GC79574 mCPX mCPX is a prodrug of the antifungal agent Ciclopirox olamine (CPX). mCPX Chemical Structure
  59. GC92129 Melanostatin (frog, eel) (trifluoroacetate salt)

    Neuropeptide Y; NPY

     Melanostatin is an endogenous peptide. Melanostatin (frog, eel) (trifluoroacetate salt) Chemical Structure
  60. GC48774 Melicopine An acridone alkaloid with antimalarial and anticancer activities Melicopine Chemical Structure
  61. GC49546 Melittin (trifluoroacetate salt) The principal cytotoxic component of bee venom Melittin (trifluoroacetate salt) Chemical Structure
  62. GC80408 Meloxicam- 13 C 6 Meloxicam -13C6 is 13 C 6 -labeled Meloxicam. Meloxicam- 13 C 6 Chemical Structure
  63. GC46169 Mer-NF5003F

    F 1839M, NF 5003F, Stachybotrydial

     A sesquiterpene with diverse biological activities Mer-NF5003F Chemical Structure
  64. GC74576 Mezagitamab

    TAK-079

     Mezagitamab (TAK-079) is a IgG1λ anti-CD38 monoclonal antibody. Mezagitamab Chemical Structure
  65. GC48479 Migrastatin

    (+)-Migrastatin

     A fungal metabolite with antimuscarinic and anticancer activities Migrastatin Chemical Structure
  66. GC78910 Mipomersen sodium scrambled negative control Mipomersen sodium scrambled negative control is the sequence scrambled negative control of Mipomersen sodium. Mipomersen sodium scrambled negative control Chemical Structure
  67. GC73018 Mirvetuximab soravtansine (solution)

    IMGN853 (solution

     Mirvetuximab soravtansine (IMGN853) solution is an anti-folate receptor α (FRα) ADC consisting of the cytotoxic maytansinoid, DM4, covalently linked to the humanized monoclonal antibody M9346A. Mirvetuximab soravtansine (solution) Chemical Structure
  68. GC44207 MitoTEMPOL MitoTEMPOL is a mitochondria-targeting superoxide dismutase mimetic that reduces mitochondrial O2- to H2O2. MitoTEMPOL Chemical Structure
  69. GC79740 ML 086 ML 086 is a highly selective PHOSPHO1 phosphatase inhibitor ( IC50 =0.14 μM). ML 086 Chemical Structure
  70. GC70326 ML 400 ML 400 is a potent and selective LMPTP inhibitor with an IC50 value of 1680 nM. ML 400 Chemical Structure
  71. GC44222 ML-298 ML-298 is an inhibitor of phospholipase D2 (PLD2; IC50 = 355 nM). ML-298 Chemical Structure
  72. GC44223 ML-299

    CID 56593087

     ML-299 is a dual inhibitor of the two mammalian forms of phospholipase D (PLD), PLD1 and PLD2 (IC50s = 6 and 20 nM, respectively). ML-299 Chemical Structure
  73. GC67798 MLS-0437605 MLS-0437605 Chemical Structure
  74. GC61408 MLS000544460 MLS000544460 is a highly selective and reversible Eya2 phosphatase inhibitor with a Kd of 2.0 μM and an IC50 of 4 μM. MLS000544460 inhibit Eya2 phosphatase mediated cell migration and has anti-cancer activity. MLS000544460 Chemical Structure
  75. GC73380 MMP-1-IN-1 MMP-1-IN-1 (Compound 6) is a highly potent MMP-1 inhibitor with an IC50 of 0.034 μM. MMP-1-IN-1 Chemical Structure
  76. GC18608 MMP-2/MMP-9 Inhibitor II

    Matrix Metalloproteinase-2/Matrix Metalloproteinase-9 Inhibitor II

     MMP-2/MMP-9 inhibitor II is a dual inhibitor of matrix metalloproteinase-2 (MMP-2) and MMP-9 (IC50s = 17 and 30 nM, respectively). MMP-2/MMP-9 Inhibitor II Chemical Structure
  77. GC69480 MMP-7-IN-1

    MMP-7-IN-1 is an effective and selective inhibitor of MMP-7 (IC50=10 nM), with IC50>11 mM for MMP-1, -2, -3, -8, -9, and -13. MMP-7 is a potential target for diseases such as cancer and fibrosis.

     MMP-7-IN-1 Chemical Structure
  78. GC71251 MMP-7-IN-2 MMP-7-IN-2 (compound 16) is a selective inhibitor of MMP7 with an IC50 value of 16 nM. MMP-7-IN-2 Chemical Structure
  79. GC73641 MMP-7-IN-3 MMP-7-IN-3 is a potent and selective inhibitor of MMP-7. MMP-7-IN-3 Chemical Structure
  80. GC79714 MMP-9-IN-13 MMP-9-IN-13 (Example 1) is a selective inhibitor of human MMP9 with an IC50 value of 0.02 nM. MMP-9-IN-13 Chemical Structure
  81. GC71106 MMP-9-IN-6 MMP-9-IN-6 (Compound 3g) is a MMP-9 inhibitor with IC50 value of 50 μM, which has good anti-ulcer effect. MMP-9-IN-6 Chemical Structure
  82. GC73941 MMP-9/10-IN-2 MMP-9/10-IN-2 (compound 6e) is a potent inhibitor of MMP10 and MMP9, with IC50 of 0.076 μM for MMP10, and 93.18% inhibition at 0.5 μM for MMP9. MMP-9/10-IN-2 Chemical Structure
  83. GC18612 MMP-9/MMP-13 Inhibitor I

    Matrix Metalloproteinase-9/Matrix Metalloproteinase-13 Inhibitor I

     MMP-9/MMP-13 inhibitor I is a cell-permeable inhibitor of matrix metalloproteinases (MMPs) that most potently inhibits MMP-9 and MMP-13 (IC50s = 0.9 nM for both). MMP-9/MMP-13 Inhibitor I Chemical Structure
  84. GC69479 MMP2-IN-1

    MMP2-IN-1 is a moderately effective inhibitor of MMP2, with an IC50 of 6.8 μM. MMP2-IN-1 exhibits significant anti-proliferative activity in certain cancer cells by blocking the cell cycle and inducing apoptosis.

     MMP2-IN-1 Chemical Structure
  85. GC44239 Mn(III)TMPyP Mn(III)TMPyP is a manganese-porphyrin which acts as a superoxide dismutase (SOD) mimetic and peroxynitrite decomposition catalyst. Mn(III)TMPyP Chemical Structure
  86. GC17832 MOCAc-PLGL(Dpa)AR MOCAc-PLGL(Dpa)AR is a fluorescent substrate specifically designed for the detection of matrix metalloproteinases (MMPs), which is suitable for the activity of MMP-2, MMP-7 and MMP-9. MOCAc-PLGL(Dpa)AR Chemical Structure
  87. GC74581 Modakafusp alfa

    TAK-573

     Modakafusp alfa (TAK-573) is a humanized, anti-CD38 IgG4 monoclonal antibody fused to 2 attenuated IFNα2b molecules, which delivers interferon-alpha to CD38-expressing cells. Modakafusp alfa Chemical Structure
  88. GP23940 MOG Myelin Oligodendrocyte Glycoprotein MOG Chemical Structure
  89. GC64031 MP07-66 MP07-66, a FTY720 analogue, is devoid of immunosuppressive effects and shows promising antitumor effects in chronic lymphocytic leukemia by disruption of the SET-PP2A complex leading to PP2A reactivation. MP07-66 Chemical Structure
  90. GC69512 Muromonab

    Muromonab is a monoclonal antibody that targets the CD3 receptor. It can block all cytotoxic T cell functions. Muromonab is also used as an immunosuppressant to reduce acute solid organ transplant rejection reactions.

     Muromonab Chemical Structure
  91. GC74435 Muzastotug Muzastotug is a humanized immunoglobulin G1-kappa, anti-CTLA4 monoclonal antibody. Muzastotug Chemical Structure
  92. GC64030 MY10 MY10 is a potent and orally active receptor protein tyrosine phosphatase (RPTPβ/ζ) inhibitor. MY10 Chemical Structure
  93. GC69515 MY33-3

    MY33-3 is an effective and selective inhibitor of protein tyrosine phosphatase RPTPβ/ζ, with an IC50 value of ~0.1 μM. MY33-3 also inhibits PTP-1B (IC50 ~0.7 μM). MY33-3 can reduce ethanol consumption and alleviate neuroinflammation and cognitive dysfunction caused by Sevoflurane.

     MY33-3 Chemical Structure
  94. GC64605 MY33-3 hydrochloride MY33-3 hydrochloride is a potent and selective inhibitor of receptor protein tyrosine phosphatase (RPTP)β/ζ, with an IC50 of ~0.1 μM. MY33-3 hydrochloride Chemical Structure
  95. GC20041 Myoglobin from equine skeletal muscle Myoglobin from equine skeletal muscle is a mobile carrier of oxygen molecules that plays a significant role in myocardial and skeletal muscle cells. Myoglobin from equine skeletal muscle Chemical Structure
  96. GC47720 N,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine A microbial metabolite with anticancer activity N,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine Chemical Structure
  97. GC44293 N-Acetyl ACTH (1-17) (human) (trifluoroacetate salt)

    Ac-SYSMEHFRWGKPVGKKR, N-Acetyl Adrenocorticotropic Hormone (1-17)

     N-Acetyl ACTH (1-17) is an N-terminal peptide fragment of adrenocorticotropic hormone (ACTH), a peptide hormone found in the brain that is involved in the biological stress response. N-Acetyl ACTH (1-17) (human) (trifluoroacetate salt) Chemical Structure
  98. GC44294 N-acetyl Dapsone

    NSC 27184

     N-acetyl Dapsone is a metabolite of dapsone, an anti-inflammatory and antibacterial compound that is widely used in the treatment of leprosy, malaria, acne, and various immune disorders. N-acetyl Dapsone Chemical Structure
  99. GC47735 N-acetyl Desethylchloroquine-d4

    N-acetyl-(mono) Desethylchloroquine

     An internal standard for the quantification of N-acetyl desethylchloroquine N-acetyl Desethylchloroquine-d4 Chemical Structure
  100. GC52007 N-hydroxylamine Dapsone

    Dapsone hydroxylamine, DDS-NHOH

     An active metabolite of dapsone N-hydroxylamine Dapsone Chemical Structure
  101. GC49357 N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 2-ethylbutyl ester A synthetic intermediate N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 2-ethylbutyl ester Chemical Structure

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