Calcium Channel
Calcium channel is an ion channel that selectively permeable to calcium ions. It serves vital functions in cellular signal transduction.
Products for Calcium Channel
- Cat.No. Product Name Information
- GC31873 NecroX-5 A necrosis inhibitor
- GC36713 Ned 19 Ned 19 is a selective membrane-permeant non competitive NAADP antagonist and inhibits NAADP-mediated Ca2+ signaling, with an IC50 of 65 nM. Ned 19 strongly inhibits tumor growth and vascularization as well as lung metastases in mice.
- GC50308 Ned K NAADP signaling inhibitor
-
GC13352
Neomycin sulfate
Aminoglycoside antibiotic
- GC32563 Nexopamil racemate Nexopamil racemate is the racemate of Nexopamil.
- GC30986 Nicardipine (YC-93) Nicardipine (YC-93) (YC-93 free base) is a calcium channel blocker with an IC50 of 1 μM for blocking cardiac calcium channels.
- GC10678 Nicardipine HCl Nicardipine HCl (YC-93) is a calcium channel blocker with an IC50 of 1 μM for blocking cardiac calcium channels.
- GC64870 Nicardipine-d3 hydrochloride Nicardipine D3 hydrochloride (YC-93 D3) is the deuterium labeled Nicardipine hydrochloride.
- GC15024 Nifedipine L-type calcium channel blocker
- GC40207 Nifedipine-d6 Nifedipine-d6 is intended for use as an internal standard for the quantification of nifedipine by GC- or LC-MS.
-
GC13698
Nilvadipine
Calcium channel inhibitor
- GC16587 Nimodipine Calcium Channel inhibitor & Autophagy activator
- GC16889 Nisoldipine calcium channel blocker
- GC62196 Nisoldipine-d7
- GC16999 Nitrendipine Calcium channel blocker
-
GC69566
Nitrendipine-d5
Nitrendipine-d5 is the deuterated form of Nitrendipine. Nitrendipine (BAY-E-5009) is a similar compound to Nifedipine. It is a dihydropyridine calcium channel blocker with vasodilatory properties and has antihypertensive effects.
- GC14417 NNC 55-0396 A selective T-type calcium channel inhibitor
- GC63118 Norverapamil D7 hydrochloride Norverapamil-d7 ((±)-Norverapamil-d7) hydrochloride is a deuterium labeled Norverapamil.
- GC32518 Norverapamil hydrochloride ((±)-Norverapamil hydrochloride) Norverapamil hydrochloride ((±)-Norverapamil hydrochloride) ((±)-Norverapamil hydrochloride ((±)-Norverapamil hydrochloride)), an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor.
- GC61139 Nothofagin Nothofagin, a dihydrochalcone, is isolated from rooibos (Aspalathus linearis).
- GC36766 NP118809 NP118809 is a potent N-type calcium channel blocker, with an IC50 of 0.11 μM; also less potently inhibits L-type calcium channel with an IC50 of 12.2 μM.
- GC30997 NS-638 NS-638 is a small nonpeptide molecule with Ca2+-channel blocking properties.
- GC45536 Oleic Acid-13C
- GC36843 Palonidipine Palonidipine is a calcium antagonist which is potential for the therapy of angina-pectoris and hypertension.
- GC11082 Paxilline Paxilline, a tremorogenic fungal alkaloid, potently inhibits large conductance Ca2+ and voltage-activated K+(BK)-type channels, IC50 is approximately 10nM, Ki=1.9nM..
- GC11678 PD 173212 N-type voltage-gated calcium channel blocker
- GC32649 PD0176078 PD0176078 is a newly found N-type Calcium channel blocker.
- GC10458 Penfluridol Dopamine receptor antagonist
- GC30055 Pinaverium bromide Pinaverium bromide is an L-type calcium channel blocker with selectivity for the gastrointestinal tract, effectively relieves pain, diarrhea and intestinal discomfort, provides good therapeutic efficacies without significant adverse effects on Irritable bowel syndrome (IBS) patients.
- GC36955 Praeruptorin E Praeruptorin E is a main bioactive constituent of Peucedanum praeruptorum (also known as Bai-Hua Qian Hu).
- GC38230 Pranidipine Pranidipine (OPC-13340) is a potent, long acting 1,4-dihydropyridine calcium channel blocker with antihypertensive activity.
- GC61933 Propiverine hydrochloride Propiverine hydrochloride is a bladder spasmolytic with calcium antagonistic and anticholinergic properties.
- GC10358 ProTx I CaV3.1 channel blocker
- GC44796 Quin-2 (potassium salt) Quin-2 is a high-affinity fluorescent calcium indicator (Kd = 115 nM for calcium).
- GC14487 Ranolazine Anti-ischemic
- GC13882 Ranolazine 2HCl Ranolazine 2HCl (CVT 303 dihydrochloride) is an anti-angina drug that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP).
- GC44827 Rhod-2 (potassium salt) Rhod-2 (potassium salt) is a water-soluble, red fluorescent calcium indicator.
-
GC44828
Rhod-2 (sodium salt)
Rhod-2 (sodium salt) is a water-soluble, red fluorescent calcium indicator.
- GC44829 Rhod-5N (potassium salt) Rhod-5N is a low affinity fluorescent calcium probe (Kd = 320 μM).
- GC44830 Rhod-5N AM Rhod-5N AM is a cell-permeant acetoxymethyl ester of the fluorescent calcium indicator rhod-5N.
- GC44834 Rhod-FF (potassium salt) Rhod-FF is a difluorinated analog of the cell-impermeant calcium indicator rhod-2.
- GC44835 Rhod-FF AM Rhod-FF AM is a cell-permeant acetoxymethyl ester of the fluorescent calcium indicator rhod-FF.
- GC60330 Ru360
-
GC16766
Ruthenium Red
Blocks Ca2+ uptake and release, and voltage-sensitive Ca2+ channels
- GC12607 Ryanodine Potent inhibitor of Ca2+ release from sarcoplasmic reticulum
- GC13016 Safinamide
- GC50392 SAK 3 Potent CaV3.1 and 3.3 activator; orally bioavailable
- GC32539 Semotiadil recemate fumarate Semotiadil recemate fumarate is the recemate of Semotiadil fumarate.
- GC64311 SERCA2a activator 1 SERCA2a activator 1 (Compound A) is a sarco/endoplasmic reticulum Ca2+-dependent ATPase 2a (SERCA2a) activator.
- GC11041 Sipatrigine voltage-dependent sodium channels (NaV) blocker
- GC32552 SM-6586 SM-6586 is a calcium channel antagonist and inhibitor of Na+/H+ and Na+/Ca2+ exchange transport, potentially for the treatment of cerebrovasular diseases and hypertension.
- GC44905 SMI-481 SMI-481 is a selective inhibitor of the yeast phosphatidylinositol transfer protein (PITP) Sec14.
- GC15237 SNX 482 voltage-dependent R-type CaV2.3 calcium channel blocker
-
GC69925
SOICR-IN-1
SOICR-IN-1 (compound 32) is an inhibitor of store-overload induced calcium release (SOICR), with an IC50 value of 14.6 μM. SOICR-IN-1 can be used for research on cardiac arrhythmias.
- GC32603 SQ-31765 (SQ31765) SQ-31765 (SQ31765) is a benzazepine calcium channel blocker.
- GC10351 SR 33805 oxalate Ca2+ channel antagonist
- GC61292 SR33805 SR33805 is a potent Ca2+ channel antagonist, with EC50s of 4.1 nM and 33 nM in depolarized and polarized conditions, respectively.
- GC15678 STO-609 acetate Ca2+-calmodulin-dependent protein kinase kinase inhibitor
- GC11819 Strontium Ranelate Calcium Channel activator
- GC33732 Syntide 2 A protein kinase substrate
- GC37710 Syntide 2 (TFA)
- GC31038 TDN345 TDN345 is a Ca2+ antagonist, used for the treatment of vascular and senile dementia including Alzheimer's disease.
- GC33176 Teludipine hydrochloride (GR53992B) Teludipine is a lipophilic calcium channel blocker.
- GC39186 Terodiline hydrochloride Terodiline hydrochloride is an M1-selective muscarinic receptor (mAChR) antagonist with Kbs of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atria (M2), bladder (M3) and ileal muscle (M3), respectively.
- GC12911 Tetracaine HCl Anaesthetic and allosteric inhibitor
- GN10446 Tetrandrine
-
GC11482
Thapsigargin
Thapsigargin?is an inhibitor of the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase pump.
- GC32549 Tiapamil hydrochloride (Ro 11-1781) Tiapamil hydrochloride (Ro 11-1781) is a calcium channel blocker.
- GC19438 TMB 8 (hydrochloride) TMB 8 is a non-competitive antagonist of nicotinic acetylcholine receptors (nAChRs) with IC50 values of 390 and 350 nM, respectively, for human muscle-type and α3β4 subunit-containing ganglionic nAChRs expressed in TE671/RD or SH-SY5Y cells.
- GC16149 Topiramate An anticonvulsant
- GC50198 Topiramate - d12 Deuterated topiramate
- GC61342 TPC2-A1-N TPC2-A1-N is a powerful and Ca2+-permeable agonist of?two pore?channel?2?(TPC2), which plays its role by mimicking the physiological actions?of?NAADP.
- GC15323 TRAM 39 Potent KCa3.1 blocker
- GC16322 trans-Ned 19 Nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist
- GC49217 Trifluoperazine N-Glucuronide A metabolite of trifluoperazine
- GC48204 Trifluoperazine-d3 (hydrochloride) An internal standard for the quantification of trifluoperazine
- GC33458 Trimethadione (3,5,5,-Trimethyloxazolidine-2,4-dione) Trimethadione (3,5,5,-Trimethyloxazolidine-2,4-dione) (3,5,5,-Trimethyloxazolidine-2,4-dione) is an oxazolidinedione anticonvulsant agent widely used against absences seizures.
- GC30950 TTA-Q6 TTA-Q6 is a selective antagonist of T-type Ca2+ channel and can be used in neurological research.
- GC50371 UK 59811 hydrochloride CaVAb blocker
- GC32571 UK51656 UK51656 is a calcium antagonist with IC50 of 4 nM.
- GC60377 Urolithin C Urolithin C, a gut-microbial metabolite of Ellagic acid, is a glucose-dependent activator of insulin secretion.
- GC61811 Verapamil Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor.
-
GC70115
Verapamil EP Impurity C hydrochloride
NSC-609249 hydrochloride is an impurity of Verapamil. Verapamil is a calcium channel blocker and an effective oral first-generation P-glycoprotein (P-gp) inhibitor.
- GC17106 Verapamil HCl Verapamil HCl ((±)-Verapamil HCl) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor.
-
GC15583
W-13 hydrochloride
calmodulin antagonist
- GC16962 W-5 hydrochloride calmodulin antagonist
- GC17496 W-7 hydrochloride calmodulin antagonist
- GC11260 W-9 hydrochloride calmodulin antagonist
- GC37950 Yangambin Yangambin, a furofuran lignan, is already isolated from plants such as member of the Annonaceae family, including species of the genus Rollinia: R.
- GC14665 YM 58483 store-operated Ca2+ entry (SOCE) blocker
- GC32648 YS-201 YS-201 is a dihydropyridine-type calcium channel antagonist.
- GC50432 Z 944 CaV3.x blocker
- GC63265 Ziconotide acetate Ziconotide acetate (SNX-111 acetate), a peptide, is a potent and selective block of N-type calcium channels antagonist.
- GC11735 Zonisamide Antiepileptic with anticonvulsant and mechanistic effect
- GC17952 Zonisamide sodium Antiepileptic drug
- GC30807 ZSET1446 (ST-101) ZSET1446 (ST-101) is a novel cognitive enhancer that significantly improves learning deficits in various types of Alzheimer disease (AD) models.