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Cyclooxygenase

Products for  Cyclooxygenase

  1. Cat.No. Product Name Information
  2. GC41174 Pinane Thromboxane A2 Pinane thromboxane A2 (PTA2) is a stable analog of TXA2. Pinane Thromboxane A2  Chemical Structure
  3. GC18271 Polmacoxib Polmacoxib is an inhibitor of cyclooxygenase 2 (COX-2) and the carbonic anhydrase subtypes I (CAI) and CAII. Polmacoxib  Chemical Structure
  4. GC44670 PPA PPA is the product of peroxidase-catalyzed reduction of PPHP. PPA  Chemical Structure
  5. GC44672 PPHP PPHP is a substrate for the measurement of peroxidase enzymes. PPHP  Chemical Structure
  6. GC52270 Pranoprofen-13C-d3 An internal standard for the quantification of pranoprofen Pranoprofen-13C-d3  Chemical Structure
  7. GC18310 Prostaglandin A1

    Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen.

    Prostaglandin A1  Chemical Structure
  8. GC18855 Prostaglandin A1 ethyl ester Prostaglandin A1 (PGA1) ethyl ester is a prodrug form of PGA1 with enhanced lipid solubility. Prostaglandin A1 ethyl ester  Chemical Structure
  9. GC40340 Prostaglandin A1 methyl ester Prostaglandin A1 (PGA1) has been shown to cause renal vasodilation, increase urine sodium excretion, and lowers arterial pressure in hypertensive patients. Prostaglandin A1 methyl ester  Chemical Structure
  10. GC18353 Prostaglandin A2 A naturally occurring prostaglandin with antiviral/antitumor activity Prostaglandin A2  Chemical Structure
  11. GC52377 Prostaglandin A2 ethyl ester An ester form of PGA2 Prostaglandin A2 ethyl ester  Chemical Structure
  12. GC44704 Prostaglandin A2 methyl ester Prostaglandin A2 (PGA2) is a naturally occurring PG in gorgonian corals where it may function in self defense. Prostaglandin A2 methyl ester  Chemical Structure
  13. GC47983 Prostaglandin A2-d4 An internal standard for the quantification of prostaglandin A2 Prostaglandin A2-d4  Chemical Structure
  14. GC40765 Prostaglandin A3 Cyclooxygenase metabolism of EPA to produce Prostaglandin E3 (PGE3) has been reported in biosynthetic preparations of ovine seminal vesicles and in the ocular tissues of primates. Prostaglandin A3  Chemical Structure
  15. GC18250 Prostaglandin B1 Prostaglandin B1 (PGB1) is a non-enzymatic dehydration product of PGE1 resulting from treatment with strong base. Prostaglandin B1  Chemical Structure
  16. GC18411 Prostaglandin B2

    Prostaglandin B2 (PGB2) is a non-enzymatic dehydration product resulting from the treatment of PGE2 or PGA2 with strong base.

    Prostaglandin B2  Chemical Structure
  17. GC47984 Prostaglandin B2-d4 An internal standard for the quantification of prostaglandin B2 Prostaglandin B2-d4  Chemical Structure
  18. GC40766 Prostaglandin B3 Prostaglandin B3 (PGB3) is a non-enzymatic dehydration product resulting from the treatment of Prostaglandin E3 (PGE3) with strong base. Prostaglandin B3  Chemical Structure
  19. GC45551 Prostaglandin Bx   Prostaglandin Bx  Chemical Structure
  20. GC45770 Prostaglandin D Synthase (hematopoietic-type) Inhibitor F092 An inhibitor of hematopoietic-type PGDS Prostaglandin D Synthase (hematopoietic-type) Inhibitor F092  Chemical Structure
  21. GC18999 Prostaglandin D1 Prostaglandin D1 (PGD1) is the theoretical D-series metabolite of DGLA, but to date it has not been isolated as a natural product. Prostaglandin D1  Chemical Structure
  22. GC18878 Prostaglandin D1 Alcohol Prostaglandin D1(PGD1) alcohol is the synthetic analog of PGD1 with a primary alcohol in place of the C-1 carboxyl. Prostaglandin D1 Alcohol  Chemical Structure
  23. GC44707 Prostaglandin D2 Ethanolamide Prostaglandin D2 ethanolamide (PGD2-EA) is a bioactive lipid produced by the sequential metabolism of anandamide (arachidonoyl ethanolamide) by cyclooxygenase (COX) enzymes, in particular by COX-2, and PGD synthase. Prostaglandin D2 Ethanolamide  Chemical Structure
  24. GC41170 Prostaglandin D2 methyl ester Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is produced in large quantities by hematopoietic PGD synthase during allergic and asthmatic anaphylaxis. Prostaglandin D2 methyl ester  Chemical Structure
  25. GC44709 Prostaglandin D2 serinol amide 2-Arachidonyl glycerol (2-AG) exhibits cannabinoid (CB) agonist activity at the CB1 receptor, is an important endogenous monoglyceride species, and is thus considered to be the natural ligand for the CB1 receptor. Prostaglandin D2 serinol amide  Chemical Structure
  26. GC44710 Prostaglandin D2-1-glyceryl ester 2-Arachidonoyl glycerol has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1 receptor. Prostaglandin D2-1-glyceryl ester  Chemical Structure
  27. GC47988 Prostaglandin D2-d4 An internal standard for the quantification of prostaglandin D2 Prostaglandin D2-d4  Chemical Structure
  28. GC40610 Prostaglandin D3 Prostaglandin D3 (PGD3) is produced by the metabolism of EPA via the COX pathway. Prostaglandin D3  Chemical Structure
  29. GC18740 Prostaglandin E1 Alcohol

    Prostaglandin E1 (PGE1) alcohol is a non-irritant bronchodilator, with relaxant activity on the human bronchial muscle in vitro, comparable to PGE1 at concentrations of 0.01 to 10.0 ug/ml.

    Prostaglandin E1 Alcohol  Chemical Structure
  30. GC18738 Prostaglandin E1 Ethanolamide Prostaglandin E1 ethanolamide (PGE1-EA) is the ethanolamine-amide analog of PGE1. Prostaglandin E1 Ethanolamide  Chemical Structure
  31. GC18768 Prostaglandin E1 ethyl ester Prostaglandin E1 (PGE1) is the theoretical cyclooxygenase metabolite of dihomo-γ-linolenic acid. Prostaglandin E1 ethyl ester  Chemical Structure
  32. GC47990 Prostaglandin E1 isopropyl ester An ester prodrug form of PGE1 Prostaglandin E1 isopropyl ester  Chemical Structure
  33. GC47991 Prostaglandin E1-d4 An internal standard for the quantification of prostaglandin E1 Prostaglandin E1-d4  Chemical Structure
  34. GC44712 Prostaglandin E2 Ethanolamide Prostaglandin E2 ethanolamide (PGE2-EA) is an analog of PGE2 with improved water solubility and stability. Prostaglandin E2 Ethanolamide  Chemical Structure
  35. GC44714 Prostaglandin E2 isopropyl ester Prostaglandin E2 (PGE2) isopropyl ester is a more lipophilic form of the free acid, PGE2. Prostaglandin E2 isopropyl ester  Chemical Structure
  36. GC41171 Prostaglandin E2 methyl ester Prostaglandin E2 methyl ester (PGE2 methyl ester) is an analog of PGE2 with enhanced lipid solubility. Prostaglandin E2 methyl ester  Chemical Structure
  37. GC44715 Prostaglandin E2 p-acetamidophenyl ester PGE2 p-acetamidophenyl ester is a crystalline derivative of PGE2. Prostaglandin E2 p-acetamidophenyl ester  Chemical Structure
  38. GC44716 Prostaglandin E2 p-benzamidophenyl ester PGE2 p-benzamidophenyl ester is a crystalline derivative of PGE2. Prostaglandin E2 p-benzamidophenyl ester  Chemical Structure
  39. GC44717 Prostaglandin E2 serinol amide 2-Arachidonyl glycerol (2-AG) exhibits cannabinoid agonist activity at the CB1 receptor, is an important endogenous monoglyceride species, and is thus considered to be the natural ligand for the CB1 receptor. Prostaglandin E2 serinol amide  Chemical Structure
  40. GC44718 Prostaglandin E2-1-glyceryl ester 2-Arachidonoyl glycerol has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1 receptor. Prostaglandin E2-1-glyceryl ester  Chemical Structure
  41. GC47994 Prostaglandin E2-d4 An internal standard for the quantification of prostaglandin E2 Prostaglandin E2-d4  Chemical Structure
  42. GC47996 Prostaglandin E2-d9 An internal standard for the quantification of PGE2 Prostaglandin E2-d9  Chemical Structure
  43. GC40611 Prostaglandin E3

    Prostaglandin E3 (PGE3) is formed via the cyclooxygenase (COX) metabolism of eicosapentaenoic acid.

    Prostaglandin E3  Chemical Structure
  44. GC47997 Prostaglandin F1α-d9 An internal standard for the quantification of PGF Prostaglandin F1α-d9  Chemical Structure
  45. GC18665 Prostaglandin F1α

    Prostaglandin F1α (PGF1α) is the putative metabolite of dihomo-γ-linolenic acid (DGLA) via the cyclooxygenase (COX) pathway.

    Prostaglandin F1α  Chemical Structure
  46. GC18920 Prostaglandin F1α Alcohol Prostaglandin F1α (PGF1α) alcohol is an analog of PGF1α with a primary alcohol replacing the C-1 carboxyl group. Prostaglandin F1α Alcohol  Chemical Structure
  47. GC18865 Prostaglandin F1β PGF1β is the C-9 epimer of PGF1α. Prostaglandin F1β  Chemical Structure
  48. GC41140 Prostaglandin F2α 1,11-lactone PGF2α 1,11-lactone is a lipid-soluble internal ester of PGF2α. Prostaglandin F2α 1,11-lactone  Chemical Structure
  49. GC41141 Prostaglandin F2α 1,15-lactone PGF2α 1,15-lactone is a lipid-soluble internal ester of PGF2α. Prostaglandin F2α 1,15-lactone  Chemical Structure
  50. GC41142 Prostaglandin F2α 1,9-lactone PGF2α 1,9-lactone is a lipid-soluble internal ester of PGF2α. Prostaglandin F2α 1,9-lactone  Chemical Structure
  51. GC40401 Prostaglandin F2α Alcohol methyl ether Prostaglandin F2α alcohol methyl ether (PGF2α-OMe) is an analog of PGF2α in which the C-1 carboxyl group has been replaced an O-methyl ether. Prostaglandin F2α Alcohol methyl ether  Chemical Structure
  52. GC44722 Prostaglandin F2α dimethyl amide Prostaglandin F2α (PGF2α) dimethyl amide is a weak FP receptor antagonist. Prostaglandin F2α dimethyl amide  Chemical Structure
  53. GC41407 Prostaglandin F2α Ethanolamide Prostaglandin F2α ethanolamide (PGF2α-EA) is produced by COX-2 metabolism of the endogenous cannabinoid, arachidonoyl ethanolamide (AEA), found in brain, liver, and other mammalian tissues. Prostaglandin F2α Ethanolamide  Chemical Structure
  54. GC44723 Prostaglandin F2α ethyl amide Prostaglandin F2α ethyl amide (PGF2α-NEt) is an analog of PGF2α in which the C-1 carboxyl group has been modified to an N-ethyl amide. Prostaglandin F2α ethyl amide  Chemical Structure
  55. GC44724 Prostaglandin F2α isopropyl ester PGF2α isopropyl ester is an ester prodrug of PGF2α with enhanced lipid solubility. Prostaglandin F2α isopropyl ester  Chemical Structure
  56. GC44725 Prostaglandin F2α-1-glyceryl ester 2-Arachidonoyl glycerol has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the central cannabinoid receptor. Prostaglandin F2α-1-glyceryl ester  Chemical Structure
  57. GC48000 Prostaglandin F2α-d4 A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications Prostaglandin F2α-d4  Chemical Structure
  58. GC44727 Prostaglandin F2β (tromethamine salt) Prostaglandin F2β (PGF2β) (tromethamine salt) is a derivative of PGF2β with increased water solubility. Prostaglandin F2β (tromethamine salt)  Chemical Structure
  59. GC18914 Prostaglandin F2α Alcohol Prostaglandin F2α alcohol (PGF2α-OH) is an analog of PGF2α in which the C-1 carboxyl group has been reduced to a primary alcohol. Prostaglandin F2α Alcohol  Chemical Structure
  60. GC18819 Prostaglandin F2α dimethyl amine PGF2α dimethyl amine is a derivative of PGF2α which was designed as a PG antagonist for in vitro and in vivo studies. Prostaglandin F2α dimethyl amine  Chemical Structure
  61. GC18370 Prostaglandin F2α methyl ester Prostaglandin F2α methyl ester (PGF2α methyl ester) is an analog of PGF2α in which the C-1 carboxyl group has been esterified as the methyl ester. Prostaglandin F2α methyl ester  Chemical Structure
  62. GC41429 Prostaglandin F3α PGF3α is a COX product of EPA. Prostaglandin F3α  Chemical Structure
  63. GC18390 Prostaglandin G2 Prostaglandin G2 (PGG2) is the first intermediate in the COX pathway which is stable enough to be isolated and characterized. Prostaglandin G2  Chemical Structure
  64. GC18791 Prostaglandin H1 Prostaglandin H1 (PGH1) is a COX metabolite of DGLA and is the precursor to all 1-series PGs and thromboxanes. Prostaglandin H1  Chemical Structure
  65. GC18381 Prostaglandin H2

    Prostaglandin H2 (PGH2) was first isolated from incubations of arachidonic acid with ovine seminal vesicle microsomes, and was described as a potent vasoconstrictor.

    Prostaglandin H2  Chemical Structure
  66. GC44728 Prostaglandin I3 (sodium salt) PGI3 is synthesized from EPA by COX and PGI synthase. Prostaglandin I3 (sodium salt)  Chemical Structure
  67. GC18653 Prostaglandin J2

    Prostaglandin J2 (PGJ2) is formed from PGD2 by the elimination of the C-9 hydroxyl group, a process which is accelerated by the presence of albumin.

    Prostaglandin J2  Chemical Structure
  68. GC41430 Prostaglandin K1 PGK1 is the 9,11-diketone formed by the oxidation of PGE1 or PGD1. Prostaglandin K1  Chemical Structure
  69. GC18753 Prostaglandin K2 Prostaglandin K2 (PGK2) is the 9,11-diketone formed by the oxidation of PGE2 or PGD2. Prostaglandin K2  Chemical Structure
  70. GC44845 Rivenprost

    Prostaglandin E2 activates four distinct G protein-coupled receptors, EP1-4.

    Rivenprost  Chemical Structure
  71. GC44863 S-5751 S-5751 is an antagonist of the prostaglandin D2 (PGD2) receptor DP1 (Ki = 1.6 nM) that shows at least 20-fold selectivity over receptors for thromboxane and prostacyclin, as well as the PGE2 receptor EP2. S-5751  Chemical Structure
  72. GC49480 Salicylic Acid-d4 Salicylic Acid-d4 is the deuterium labeled 2-Carboxyphenol. Salicylic Acid-d4  Chemical Structure
  73. GC49363 Salicyluric Acid A major metabolite of aspirin and salicylic acid Salicyluric Acid  Chemical Structure
  74. GC40866 Tafluprost (free acid) Tafluprost (free acid) (AFP-172), an active metabolic form of Tafluprost, is a selective prostanoid FP receptor agonist. Tafluprost (free acid)  Chemical Structure
  75. GC18573 Tafluprost ethyl amide Tafluprost ethyl amide is derived from 17-phenyl trinor Prostaglandin F2α(17-phenyl trinor PGF2α). Tafluprost ethyl amide  Chemical Structure
  76. GC44985 Tafluprost ethyl ester Analogs of prostaglandin F2α (PGF2α), which act primarily at the FP receptor, have been approved for the treatment of glaucoma. Tafluprost ethyl ester  Chemical Structure
  77. GC44991 Taprostene (free acid) Taprostene (free acid) (CG-4203) is a synthetic, chemically stable analogue of Prostacyclin (PGI2). Taprostene (free acid)  Chemical Structure
  78. GC48447 TAS 205 An inhibitor of H-PGDS TAS 205  Chemical Structure
  79. GC45002 TBS-Corey Lactone Aldehyde TBS-Corey lactone aldehyde is a versatile, hydroxyl-protected intermediate for the synthesis of prostaglandins and prostaglandin analogs. TBS-Corey Lactone Aldehyde  Chemical Structure
  80. GC40069 Teleocidin A1

    Teleocidin A1, also known as lyngbyatoxin A, is a fungal metabolite that has been isolated from S.

    Teleocidin A1  Chemical Structure
  81. GC49386 Tepoxalin A dual inhibitor of COX and 5-LO Tepoxalin  Chemical Structure
  82. GC45023 tetranor-12(R)-HETE Metabolism of 12(R)-HETE in corneal tissue produces predominantly the compound resulting from the loss of four carbon atoms through β-oxidation from C-1. tetranor-12(R)-HETE  Chemical Structure
  83. GC40627 tetranor-Misoprostol tetranor-Misoprostol is a metabolite of misoprostol. tetranor-Misoprostol  Chemical Structure
  84. GC41568 tetranor-PGAM Prostaglandin E2 (PGE2), one of the most widely investigated PGs, can be used as a biomarker of inflammation, disease state, or therapeutic effectiveness. tetranor-PGAM  Chemical Structure
  85. GC45025 tetranor-PGDM Prostaglandin D2 is synthesized by hematopoietic-type PGD-synthase (H-PGDS) in mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. tetranor-PGDM  Chemical Structure
  86. GC48156 tetranor-PGDM-d6 An internal standard for the quantification of tetranorPGDM tetranor-PGDM-d6  Chemical Structure
  87. GC45026 tetranor-PGEM tetranor-PGEM is a metabolite of prostaglandin E2 (PEG2) as a biomarker of inflammation and cancer including advanced colorectal neoplasia, ovarian cancer, prostate cancer and so on. tetranor-PGEM  Chemical Structure
  88. GC48157 tetranor-PGEM-d6 An internal standard for the quantification of tetranorPGEM tetranor-PGEM-d6  Chemical Structure
  89. GC45027 tetranor-PGFM tetranor-PGFM is the major urinary metabolite of PGF2α. tetranor-PGFM  Chemical Structure
  90. GC18921 tetranor-PGJM Prostaglandin D2 (PGD2) plays a pharmacological role in allergic and asthmatic anaphylaxis, normal physiological sleep and lowering of body temperature, as well as inhibits platelet aggregation and relaxes vascular smooth muscle. tetranor-PGJM  Chemical Structure
  91. GC48158 tetranor-Prostaglandin E1 A metabolite of PGE1 and PGE2 tetranor-Prostaglandin E1  Chemical Structure
  92. GC45030 TG6-129 Prostaglandin E2 evokes distinct responses through four different 'E prostanoid' (EP) receptors. TG6-129  Chemical Structure
  93. GC45033 Thielavin A Thielavin A is a fungal metabolite originally isolated from T. Thielavin A  Chemical Structure
  94. GC45034 Thielavin B Thielavin B is a fungal metabolite that contains O-substituted salicylic acid. Thielavin B  Chemical Structure
  95. GC45052 Thromboxane B1 Dihomo-g-linolenic acid (DGLA) is one of the 20-carbon fatty acids that can be metabolized to prostaglandins and thromboxanes (TXs) by cyclooxygenases 1 and 2 (COX-1/COX-2). Thromboxane B1  Chemical Structure
  96. GC48176 Thromboxane B2-d4 An internal standard for the quantification of thromboxane B2d4 Thromboxane B2-d4  Chemical Structure
  97. GC41475 Thromboxane B3 Thromboxane B3 (TXB3) is the stable hydrolysis product of TXA3 synthesized from eicosapentaenoic acid by COX and thromboxane synthase. Thromboxane B3  Chemical Structure
  98. GC48194 trans-Resveratrol-d4 An internal standard for the quantification of trans-resveratrol trans-Resveratrol-d4  Chemical Structure
  99. GC48202 Treprostinil (diethanolamine salt) Treprostinil (UT-15C) diethanolamine is a potent EP2, DP1 and IP agonist with Ki values of 3.6, 4.4, 32.1, 212, 826, 2505 and 4680 nM for EP2, DP1, IP, EP1, EP4, EP3 and FP, respectively. Treprostinil (diethanolamine salt)  Chemical Structure
  100. GC45104 U-51605 U-51605 is a stable analog of the endoperoxide prostaglandin H2 (PGH2). U-51605  Chemical Structure
  101. GC45121 Unoprostone isopropyl ester Unoprostone isopropyl ester (Unoprostone isopropyl ester), an analogue of a prostaglandin metabolite, is a potent large conductance Ca2+-activated K+ (BK) channels activator. Unoprostone isopropyl ester  Chemical Structure

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