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Home >> Signaling Pathways >> Immunology/Inflammation >> Innate Immunity

Innate Immunity

Products for  Innate Immunity

  1. Cat.No. Product Name Information
  2. GC46826 Alclofenac An NSAID Alclofenac Chemical Structure
  3. GC49336 AMK (hydrochloride) An active metabolite of melatonin AMK (hydrochloride) Chemical Structure
  4. GC52406 AMPR-22 (trifluoroacetate salt) An antimicrobial peptide AMPR-22 (trifluoroacetate salt) Chemical Structure
  5. GC46862 Apigenin-d5 An internal standard for the quantification of apigenin Apigenin-d5 Chemical Structure
  6. GC49776 Apricitabine Apricitabine Chemical Structure
  7. GC42832 Arachidic Acid (sodium salt)

    Arachidic acid is a long-chain saturated fatty acid that has been found in peanut butter and anaerobic fungi.

     Arachidic Acid (sodium salt) Chemical Structure
  8. GC45384 Arachidic Acid-d2   Arachidic Acid-d2 Chemical Structure
  9. GC46869 Arachidic Acid-d3 An internal standard for the quantification of arachidic acid Arachidic Acid-d3 Chemical Structure
  10. GC46887 Atazanavir-d6 An internal standard for the quantification of atazanavir Atazanavir-d6 Chemical Structure
  11. GC42877 AUY954 AUY954 is an orally bioavailable and selective agonist of the sphingosine-1-phosphate receptor 1 (S1P1; EC50 = 1.2 nM for stimulating GTPγS binding to S1P1 in CHO cells). AUY954 Chemical Structure
  12. GC42880 Avenanthramide-C methyl ester Avenanthramide-C methyl ester is an inhibitor of NF-κB activation that acts by blocking the phosphorylation of IKK and IκB (IC50 ~ 40 μM). Avenanthramide-C methyl ester Chemical Structure
  13. GC42891 azido-FTY720 FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analog of sphingosine. azido-FTY720 Chemical Structure
  14. GC46903 Azithromycin-d3 An internal standard for the quantification of azithromycin Azithromycin-d3 Chemical Structure
  15. GC49302 Bactenecin (bovine) (trifluoroacetate salt) A cationic peptide Bactenecin (bovine) (trifluoroacetate salt) Chemical Structure
  16. GC18313 BAR501 Impurity BAR501 impurity is an impurity found in the preparation of BAR501 that acts as an agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1). BAR501 Impurity Chemical Structure
  17. GC42897 BAY 61-3606 (hydrochloride) BAY 61-3606 is a cell-permeable, reversible inhibitor of spleen tyrosine kinase (Syk; Ki = 7.5 nM; IC50 = 10 nM). BAY 61-3606 (hydrochloride) Chemical Structure
  18. GC18487 BC-1215 BC-1215 is an inhibitor of F-box protein 3 (FBXO3; IC50 = 0.9 μg/mL for Il-1β release). BC-1215 Chemical Structure
  19. GC49836 Benoxaprofen Benoxaprofen (LRCL 3794) is a potent and long-acting anti-inflammatory and antipyretic compound. Benoxaprofen Chemical Structure
  20. GC42925 Berteroin Berteroin is a sulforaphane analog found in cruciferous vegetables including Chinese cabbage, rucola salad leaves, and mustard oil. Berteroin Chemical Structure
  21. GC52329 Betamethasone-d5 An internal standard for the quantification of betamethasone Betamethasone-d5 Chemical Structure
  22. GC52326 Biotin-PEG4-LL-37 (human) (trifluoroacetate salt) A biotinylated and pegylated form of LL-37 Biotin-PEG4-LL-37 (human) (trifluoroacetate salt) Chemical Structure
  23. GC45951 BLX3887 A 15-LO-1 inhibitor BLX3887 Chemical Structure
  24. GC42953 BMS 345541 (trifluoroacetate salt) BMS 345541 is a cell permeable inhibitor of the IκB kinases IKKα and IKKβ (IC50s = 4 and 0.3 μM). BMS 345541 (trifluoroacetate salt) Chemical Structure
  25. GC48495 BMS-P5 BMS-P5 is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor. BMS-P5 blocks MM-induced NET formation and delays progression of MM in a syngeneic mouse model. BMS-P5 Chemical Structure
  26. GC52424 Bradykinin Fragment (1-5) (trifluoroacetate salt) A metabolite of bradykinin Bradykinin Fragment (1-5) (trifluoroacetate salt) Chemical Structure
  27. GC52101 Brazilein Brazilein is an important immunosuppressive component isolated from Caesalpinia sappan L. Brazilein Chemical Structure
  28. GC46956 Budesonide-d8 An internal standard for the quantification of budesonide Budesonide-d8 Chemical Structure
  29. GC19432 BXL-628 BXL-628 (BXL-628) is a selective, orally active vitamin D receptor (VDR) agonist. BXL-628 Chemical Structure
  30. GC46983 C-170 C-170 (C-170) is a potent and covalent STING inhibitor. C-170 Chemical Structure
  31. GC46984 C-171 C-171 is an inhibitor of stimulator of interferon genes (STING). C-171 Chemical Structure
  32. GC43032 C16 Globotriaosylceramide (d18:1/16:0) C16 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from C16 lactosylceramide. C16 Globotriaosylceramide (d18:1/16:0) Chemical Structure
  33. GC43049 C18 Globotriaosylceramide (d18:1/18:0) C18 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from lactosylceramide. C18 Globotriaosylceramide (d18:1/18:0) Chemical Structure
  34. GC45834 C24 (2'(R)-hydroxy) Phytoceramide (t18:0/24:0) A bioactive sphingolipid C24 (2'(R)-hydroxy) Phytoceramide (t18:0/24:0) Chemical Structure
  35. GC43077 C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) C24:1 3'-sulfo Galactosylceramide is a member of the sulfatide class of glycolipids. C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) Chemical Structure
  36. GC43136 Campestanol

    Campestanol is a phytosterol found in vegetables, fruits, nuts, and seeds.

     Campestanol Chemical Structure
  37. GC49761 Capsaicin-d3 Capsaicin-d3 ((E)-Capsaicin-d3) is the deuterium labeled Capsaicin. Capsaicin ((E)-Capsaicin), an active component of chili peppers, is a TRPV1 agonist. Capsaicin has pain relief, antioxidant, anti-inflammatory, neuroprotection and anti-cancer effects. Capsaicin-d3 Chemical Structure
  38. GC49433 Capsiate A capsaicin analog with diverse biological activities Capsiate Chemical Structure
  39. GC47040 Carebastine-d5 An internal standard for the quantification of carebastine Carebastine-d5 Chemical Structure
  40. GC47046 Carviolin A fungal metabolite with immunosuppressive and antitrypanosomal activities Carviolin Chemical Structure
  41. GC18856 CAY10526 Prostaglandin E2 (PGE2) is the major PG synthesized at sites of inflammation and plays an important role in different inflammatory diseases. CAY10526 Chemical Structure
  42. GC43176 CAY10575 CAY10575 (Compound 8) is an IKK2 inhibitor with an IC50 of 0.075 μM. CAY10575 Chemical Structure
  43. GC41601 CAY10591 CAY10591 is a potent activator of Sirt1 and suppresses TNF-α in a dose-dependent manner. CAY10591 Chemical Structure
  44. GC43181 CAY10597 The biological effects of prostaglandin D2 (PGD2) are transduced by at least two 7-transmembrane G protein-coupled receptors, designated DP1 and CRTH2/DP2. CAY10597 Chemical Structure
  45. GC18877 CAY10606 5-Lipoxygenase (5-LO) initiates the synthesis of leukotrienes (LTs) from arachidonic acid, primarily in certain leukocyte populations. CAY10606 Chemical Structure
  46. GC18883 CAY10614 Lipid A is a lipid-rich component of endotoxin, also known as lipopolysaccharide (LPS), which in turn is part of the outer membrane of Gram-negative bacteria. CAY10614 Chemical Structure
  47. GC18910 CAY10654 The gram-negative pathogen Pseudomonas aeruginosa uses N-acylated-L-homoserine lactones (AHLs) in quorum sensing to modulate transcriptional activators, including LasR, and regulate the expression of virulence factors. CAY10654 Chemical Structure
  48. GC18782 CAY10657 The NF-κB/Rel family of transcription factors induce and coordinate the expression of pro-inflammatory genes including cytokines, chemokines, interferons, MHC proteins, growth factors, and cell adhesion molecules. CAY10657 Chemical Structure
  49. GC47054 CAY10748 A STING agonist CAY10748 Chemical Structure
  50. GC52307 CAY10790 A CysLT1 receptor antagonist and GPBAR1 agonist CAY10790 Chemical Structure
  51. GC45716 Cerevisterol A fungal metabolite Cerevisterol Chemical Structure
  52. GC52016 Cetirizine N-oxide An oxidative degradation product of cetirizine Cetirizine N-oxide Chemical Structure
  53. GC43239 Chk2 Inhibitor Chk2 Inhibitor (compound 1) is a potent and selective inhibitor of checkpoint kinase 2 (Chk2), with IC50s of 13.5 nM and 220.4 nM for Chk2 and Chk1, respectively. Chk2 Inhibitor can elicit a strong ataxia telangiectasia mutated (ATM)-dependent Chk2-mediated radioprotection effect. Chk2 Inhibitor Chemical Structure
  54. GC43242 Chloramphenicol Succinate Chloramphenicol succinate is a water-soluble prodrug form of the antibiotic chloramphenicol. Chloramphenicol Succinate Chemical Structure
  55. GC41222 Cicaprost

    Prostaglandin I2 (PGI2, prostacyclin) is the most potent endogenous vasodilator that affects both the systemic and pulmonary circulation.

     Cicaprost Chemical Structure
  56. GC49082 Cicloprofen An NSAID Cicloprofen Chemical Structure
  57. GC52363 Citrullinated Histone H3 (R2 + R8 + R17) (2-22)-biotin Peptide

    A biotinylated and citrullinated histone H3 peptide

     Citrullinated Histone H3 (R2 + R8 + R17) (2-22)-biotin Peptide Chemical Structure
  58. GC52367 Citrullinated Vimentin (G146R) (R144 + R146) (139-159)-biotin Peptide A biotinylated and citrullinated mutant vimentin peptide Citrullinated Vimentin (G146R) (R144 + R146) (139-159)-biotin Peptide Chemical Structure
  59. GC52370 Citrullinated Vimentin (R144) (139-159)-biotin Peptide A biotinylated and citrullinated vimentin peptide Citrullinated Vimentin (R144) (139-159)-biotin Peptide Chemical Structure
  60. GC47117 Colchicine-d6

    An internal standard for the quantification of colchicine

     Colchicine-d6 Chemical Structure
  61. GC47119 Colletodiol A fungal metabolite with immunosuppressive and antiviral activities Colletodiol Chemical Structure
  62. GC49266 Compstatin (trifluoroacetate salt) A peptide inhibitor of complement activation Compstatin (trifluoroacetate salt) Chemical Structure
  63. GC18572 Concanavalin A

    Concanamycin A belongs to the concanamycins, a family of macrolide antibiotics isolated from Streptomyces diastatochromogenes that are highly active and selective inhibitors of the vacuolar proton-ATPase (v-[H+]ATPase).

     Concanavalin A Chemical Structure
  64. GC43320 CPI-268456 CPI-268456 (compound 141) is a potent BRD4 inhibitor with an IC50 of <0.5 μM. CPI-268456 Chemical Structure
  65. GC45413 Cridanimod (sodium salt)   Cridanimod (sodium salt) Chemical Structure
  66. GC43325 Cromolyn (sodium salt hydrate) Cromolyn is a chromone complex that acts as a mast cell stabilizer, preventing the release of histamine. Cromolyn (sodium salt hydrate) Chemical Structure
  67. GC47128 CU-32 A cGAS inhibitor CU-32 Chemical Structure
  68. GC47129 CU-76 A cGAS inhibitor CU-76 Chemical Structure
  69. GC43339 Cyclic di-AMP (sodium salt) Cyclic di-AMP (c-di-AMP) is a second messenger produced by bacteria but not by mammals. Cyclic di-AMP (sodium salt) Chemical Structure
  70. GC19526 Cyclic di-GMP (sodium salt) Cyclic di-GMP (sodium salt) is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic di-GMP (sodium salt) has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic di-GMP (sodium salt) can be used in cancer research. Cyclic di-GMP (sodium salt) Chemical Structure
  71. GC43340 Cyclic di-IMP (sodium salt) Cyclic di-IMP (sodium salt) (c-di-IMP) is a synthetic second messenger structurally related to the bacterial second messengers cyclic di-GMP and cyclic di-AMP. Cyclic di-IMP (sodium salt) Chemical Structure
  72. GC48397 Cyclic di-UMP (sodium salt) A pyrimidine-containing CDN Cyclic di-UMP (sodium salt) Chemical Structure
  73. GC47138 Cyclizine (hydrochloride) A histamine H1 receptor antagonist Cyclizine (hydrochloride) Chemical Structure
  74. GC43395 Deethylindanomycin Deethylindanomycin is a polyether antibiotic that has been found in S. Deethylindanomycin Chemical Structure
  75. GC43398 Defensin HNP-3 (human) (trifluoroacetate salt) Defensin HNP-3 is a peptide secreted by human polymorphonuclear leukocytes (PMNs) that has antimicrobial properties. Defensin HNP-3 (human) (trifluoroacetate salt) Chemical Structure
  76. GC18517 Diapocynin Diapocynin is the dimeric form of the NADPH oxidase inhibitor apocynin that has anti-inflammatory and antioxidant activities. Diapocynin Chemical Structure
  77. GC47212 Diclofenac amide A prodrug form of diclofenac Diclofenac amide Chemical Structure
  78. GC43447 Diclofenac methyl ester Diclofenac methyl ester is a hydrophobic prodrug form of the non-steroidal anti-inflammatory drug (NSAID) diclofenac. Diclofenac methyl ester Chemical Structure
  79. GC47213 Diclofenac-d4 An internal standard for the quantification of diclofenac Diclofenac-d4 Chemical Structure
  80. GC49022 Didanosine-d2 An internal standard for the quantification of didanosine Didanosine-d2 Chemical Structure
  81. GC45662 Dieugenol A neolignan with antioxidative and antiparasitic activities Dieugenol Chemical Structure
  82. GC43453 Diflapolin Diflapolin is a dual inhibitor of 5-lipoxygenase-activating protein (FLAP) and soluble epoxide hydrolase (sEH). Diflapolin Chemical Structure
  83. GC40629 Dimethoxycurcumin Naturally occurring phytochemicals such as turmeric (curcumin) have been found to inhibit the growth of tumor cells. Dimethoxycurcumin Chemical Structure
  84. GC43467 Dimethyldioctadecylammonium (bromide) Dimethyldioctadecylammonium (DDA) is a cationic amphipathic lipid. Dimethyldioctadecylammonium (bromide) Chemical Structure
  85. GC47234 Diosmetin-d3 An internal standard for the quantification of diosmetin Diosmetin-d3 Chemical Structure
  86. GC48352 Diprovocim-1 An agonist of TLR1/TLR2 Diprovocim-1 Chemical Structure
  87. GC43492 DL-Propargyl Glycine (hydrochloride) Hydrogen sulphide (H2S), a naturally occurring gasotransmitter, is a potent vasodilator and pro-inflammatory mediator. DL-Propargyl Glycine (hydrochloride) Chemical Structure
  88. GC45995 DO264 An ABHD12 inhibitor DO264 Chemical Structure
  89. GC47278 Ebastine-d5 An internal standard for the quantification of ebastine Ebastine-d5 Chemical Structure
  90. GC43588 EGA EGA is an inhibitor of endosomal trafficking. EGA Chemical Structure
  91. GC52002 Emavusertib Emavusertib Chemical Structure
  92. GC46137 Emestrin A mycotoxin Emestrin Chemical Structure
  93. GC52334 ENPP1 Inhibitor 4e An ENPP1 inhibitor ENPP1 Inhibitor 4e Chemical Structure
  94. GC49101 Enrofloxacin-d5 An internal standard for the quantification of enrofloxacin Enrofloxacin-d5 Chemical Structure
  95. GC47295 Enviroxime An antiviral agent Enviroxime Chemical Structure
  96. GC52516 Erbstatin A tyrosine kinase inhibitor Erbstatin Chemical Structure
  97. GC47306 Esculin (hydrate) A coumarin with antioxidant and anti-inflammatory activities Esculin (hydrate) Chemical Structure
  98. GC18325 Ferrichrome (iron-free) Ferrichrome is a hydroxamate siderophore produced by various fungi, including U. Ferrichrome (iron-free) Chemical Structure
  99. GC46148 Filgotinib-d4 An internal standard for the quantification of filgotinib Filgotinib-d4 Chemical Structure
  100. GC49344 Fisetin-d5 An internal standard for the quantification of fisetin Fisetin-d5 Chemical Structure
  101. GC48827 Flufenamic Acid-d4 An internal standard for the quantification of flufenamic acid Flufenamic Acid-d4 Chemical Structure

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