Cancer Biology
- Cancer Biology Peptides(84)
- Ras-like GTPases(11)
- Leukemia(1)
- Cell Proliferation, Viability & Cytotoxicity(0)
- Others(7)
- Tumor Microenvironment(30)
- Cell Migration & Metastasis(19)
Products for Cancer Biology
- Cat.No. Product Name Information
- GC46163 IT-143B A bacterial metabolite
- GC41645 Jacaric Acid Jacaric acid is a conjugated polyunsaturated fatty acid first isolated from seeds of Jacaranda plants.
- GC41236 Kazusamycin A Kazusamycin A is an antibiotic from Streptomyces and a hydroxy analog of Leptomycin B that demonstrates cytotoxic activity against various human and mouse tumor lines.
- GC44009 KM 233 Because selective activation of peripheral cannabinoid (CB2) receptors in rat C-6 glioma cells has been shown to induce apoptosis through enhanced ceramide synthesis de novo, CB2 agonists present potential as anti glioma agents.
- GC41627 Kumbicin C Kumbicin C is a bis-indolyl benzenoid fungal metabolite produced by A.
- GC47533 L-778,123 A dual inhibitor of FTase and GGTase I
- GC47572 L-Lysine lactam (hydrochloride) A building block
- GC49368 L-Methionine-d3 An internal standard for the quantification of L-methionine
- GC44084 L-Selenocystine L-Selenocystine is a diselenide-bridged amino acid that may be confused with selenocysteine (Sec), which is a rare amino acid featuring a single selenium atom.
- GC49560 L6H21 L6H21, a Chalcone derivative, is an orally active, potent and specific myeloid differentiation 2 (MD-2) inhibitor.
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GP10103
Laminin (925-933)
Laminin (925-933)(CDPGYIGSR), is the sequence of Laminin on the B1 chain.
- GC66014 Lepidiline A Lepidiline A shows cytotoxic activity against HL-60 cells with an IC50 of 32.3 μM.
- GC66012 Lepidiline C Lepidiline C shows cytotoxic activity against HL-60 cells with an IC50 of 27.7 μM.
- GC47554 Letrozole-d4 An internal standard for the quantification of letrozole
- GC44050 Leucinostatin A Leucinostatin A is a fungal metabolite originally isolated from P.
- GC41107 Leukotriene B5 Leukotriene B5 (LTB5) is a leukotriene with diverse biological activities.
- GC49020 Levomefolate-13C-d3 An internal standard for the quantification of levomefolate
- GC18789 Lobaric Acid Lobaric acid is a depsidone metabolite that has been isolated from Stereocaulon lichen species with antioxidant, antiproliferative, antiviral, and enzyme inhibitory activites.
- GC48989 LTX-315 (trifluoroacetate salt) A synthetic cationic amphiphilic peptide
- GC52314 Lysyllysyllysine (trifluoroacetate salt) A tripeptide
- GC41185 MAGL Inhibitor Compound 23 MAGL Inhibitor Compound 23 is a potent, selective, reversible and competitive inhibitor of MAGL, with an IC50 of 80 nM. MAGL Inhibitor Compound 23 exhibits anti-proliferative effects against human breast, colorectal, and ovarian cancer cells. MAGL Inhibitor Compound 23 blocks MAGL in cell-based as well as in vivo assays.
- GC46031 Malabaricone B A diarylnonanoid with diverse biological activities
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GC44118
Malvidin (chloride)
Malvidin is an O-methylated anthocyanidin responsible for the pigments in grapes and blueberries.
- GC44126 Manzamine A Manzamine A is a β-carboline alkaloid with diverse activities that has been found in marine sponges, including X.
- GP10140 MAP kinase fragment [Multiple species]
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GC44168
Metanephrine
Metanephrine is a metabolite of epinephrine produced by the action of catechol-O-methyl transferase on epinephrine.
- GC49423 Metanephrine-d3 (hydrochloride) An internal standard for the quantification of metanephrine
- GC49879 Metformin hydroxy analog 2 An oxidation product of metformin
- GC48805 Methapyrilene (hydrochloride) An H1 receptor antagonist and non-genotoxic carcinogen
- GC47649 Methotrexate (hydrate) A folic acid and aminopterin derivative
- GC47650 Methotrexate-d3 An internal standard for the quantification of methotrexate
- GC49241 Methyl Diethyldithiocarbamate An active metabolite of disulfiram
- GC50686 Miro1 Reducer
- GC16331 Misonidazole nitroimidazole with radiosensitizing and antineoplastic properties
- GC12876 ML-097 ML-097 (CID-2160985) is a pan Ras-related GTPases activator that can activate Rac1, cell division cycle 42, Ras, and Rab7.
- GC13315 ML-098 activator of the GTP-binding protein Rab7
- GC16765 ML-099 pan activator of Ras-related GTPases
- GC18616 MMP-8 Inhibitor I MMP-8 Inhibitor I is a selective inhibitor of the neutrophil collagenase matrix metalloproteinase-8 (MMP-8) with an IC50 value of 4 nM.
- GC46176 Multiflorenol A triterpene
- GC41325 Mycophenolic Acid β-D-Glucuronide Mycophenolic Acid β-D-Glucuronide is a metabolite of the immunosuppressant mycophenolic acid (MPA). Mycophenolic Acid β-D-Glucuronide shows anti-tumor activity and can be used in adenocarcinoma research.
- GP10114 Myelopeptide-2 (MP-2)
- GC49256 N-acetyl Lenalidomide A metabolite of lenalidomide
- GC18506 N-Arachidonoyl Dopamine N-Arachidonoyl Dopamine is a potent and selective endogenous CB1 receptor agonist with a Ki of 250 nM.
- GC47748 N-Arachidonoyl Dopamine-d8 An internal standard for the quantification of Narachidonoyl dopamine
- GC48335 N-glycolyl-Ganglioside GM3 Mixture (ammonium salt) A mixture of N-glycolyl-ganglioside GM3
- GC49350 N-Nitroso Sarcosine A carcinogen
- GC49354 N-Nitroso Sarcosine-d3 An internal standard for the quantification of nitroso sarcosine
- GC47786 N-Nitroso-N-methyl-4-Aminobutyric Acid A tobacco-specific nitrosamine carcinogen
- GC49859 N-Nitroso-N-methylaniline An N-nitrosamine
- GC49731 N-Nitrosodimethylamine-d6 An internal standard for the quantification of N-nitrosodimethylamine
- GC49814 N-Nitrosomethylisopropylamine An N-nitrosamine
- GC52162 N1-Acetylputrescine
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GC44285
N1-Acetylspermine (hydrochloride)
N1-Acetylspermine is a monoacetylated derivative of spermine, an endogenous polyamine synthesized from spermidine, that displays lower Km and higher Vmax values than spermine, making it a better substrate of polyamine oxidase than the non-acetylated polyamine.
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GC40081
Nargenicin
Nargenicin is a macrolide antibiotic that selectively inhibits the growth of S.
- GC45926 Nelfinavir-d3 An internal standard for the quantification of nelfinavir
- GC47768 Neuromedin U-25 (human) (trifluoroacetate salt) A neuropeptide with diverse roles
- GC46184 Nexinhib20 An inhibitor of Rab27a-JFC1 protein-protein interactions
- GC44439 NO-Indomethacin NO-indomethacin is a hybrid molecule of indomethacin and a nitric oxide (NO) donor.
- GC49316 O-Desmethyl-N-deschlorobenzoyl Indomethacin A metabolite of indomethacin
- GC47814 Ochratoxin A-13C20 An internal standard for the quantification of ochratoxin A
- GC44507 Oligomycin E Oligomycin E is a minor metabolite of the oligomycin complex produced by several species of Streptomyces.
- GC49236 Orlistat-d3 An internal standard for the quantification of orlistat
- GC49073 Oxanosine A guanosine analog with diverse biological activities
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GP10036
p53 tumor suppressor fragment
Regulates cell cycle
- GC44531 PACAP (1-27) (human, mouse, ovine, porcine, rat) (trifluoroacetate salt) Pituitary adenylate cyclase-activating peptide (PACAP) (1-27) is a PACAP receptor agonist with IC50 values of 3, 2, and 5 nM, respectively, for rat PAC1, rat VPAC1, and human VPAC2 recombinant receptors expressed in CHO cells.
- GC44533 PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt) Pituitary adenylate cyclase-activating peptide (PACAP) (6-27) is a PACAP receptor antagonist with IC50 values of 1,500, 600, and 300 nM, respectively, for rat PAC1, rat VPAC1, and human VPAC2 recombinant receptors expressed in CHO cells.
- GC44535 PACAP-related Peptide (human) (trifluoroacetate salt) PACAP-related peptide (PRP) is an endogenous 29-amino acid peptide that belongs to the secretin/glucagon superfamily of peptides, which includes secretin, glucagon, glucagon-like peptide-1, GLP-2, and pituitary adenylate cyclase-activating polypeptide.
- GC49024 Palmitic Acid MaxSpec® Standard A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications
- GC49023 Palmitic Acid-d9 MaxSpec® Standard A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications
- GC49422 PAR2 (1-6) amide (human) (trifluoroacetate salt) A peptide agonist of PAR2
- GC47925 Pasireotide (aspartate) (trifluoroacetate salt) A somatostatin receptor agonist
- GC48493 PCI 45227 PCI 45227 (PCI-45227) is a dihydrodiolactive metabolite of Ibrutinib, has inhibitory activity towards BTK approximately 15 times lower than that of ibrutinib.
- GC52107 PEG diamine A PEGylated building block
- GC44590 Pellitorine An amide alkaloid with diverse biological activities
- GC44591 Pemetrexed (sodium salt hydrate) Pemetrexed (sodium salt hydrate) is a novel antifolate, the Ki values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively.
- GC46198 Penicinoline An alkaloid
- GC45814 Pentanoic Acid-d9 An internal standard for the quantification of pentanoic acid
- GC49530 Phenformin-d5 (hydrochloride) An internal standard for the quantification of phenformin
- GC47948 Phenoxazine A heterocyclic building block
- GC46202 Phenoxybenzamine-d5 (hydrochloride) An internal standard for the quantification of phenoxybenzamine
- GC44629 Pheophorbide a Pheophorbide a is a product of chlorophyll breakdown that has been used as a photosensitizer in photodynamic therapy for the treatment of cancer.
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GC44637
PHPS1
PHPS1 is a cell-permeable, phosphotyrosine mimetic that inhibits the Src homology region 2 domain-containing phosphatase (SHP)-2 (IC50 = 2.1 μM; Ki = 0.73 μM).
- GC49441 Plerixafor (hydrochloride hydrate) An antagonist of CXCR4
- GC49148 Plitidepsin A depsipeptide with diverse biological activities
- GC18271 Polmacoxib Polmacoxib is an inhibitor of cyclooxygenase 2 (COX-2) and the carbonic anhydrase subtypes I (CAI) and CAII.
- GC46207 Polygodial pyridazine A derivative of polygodial
- GC47965 Pomalidomide-d5 An internal standard for the quantification of pomalidomide
- GC48501 Preterramide C Preterramide C is a fungal metabolite.
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GC41572
PRLX-93936
PRLX-93936 is an analog of erastin that has antitumor activity.
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GP10072
Pro-Adrenomedullin (153-185), human
Vasodilator
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GC18310
Prostaglandin A1
Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen.
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GP10002
prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens]
Transcriptional repressor
- GC48406 PSI (trifluoroacetate salt) A proteasome inhibitor
- GC49914 Pt(II)-NHC Complex 2C An inducer of immunogenic cancer cell death
- GC52484 Purified Ganglioside Mixture (bovine) (ammonium salt) A mixture of purified bovine gangliosides
- GC40568 Pyrocoll Pyrocoll is a bacterial metabolite originally isolated from Streptomyces.
- GC44791 Pyrrolidine Linoleamide Linoleic acid is an essential fatty acid and one of the most abundant polyunsaturated fatty acids in the western diet.
- GC44792 Pyrrolidine Ricinoleamide Ricinoleic acid is a naturally occurring 12-hydroxy fatty acid.
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GP10032
Rac GTPase fragment
Fragment of small signaling G proteins
- GC10906 RBC8 Ral GTPase inhibitor