Neuroscience

Neuroscience
Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides).
Targets for Neuroscience
- 5-HT Receptor(533)
- AChR(57)
- AChE(103)
- Alzheimer(115)
- Amyloid β(130)
- BACE(5)
- CGRP (34)
- COX(302)
- DAPK(7)
- Dopamine Receptor(307)
- GABA Receptor(237)
- Gap Junction(15)
- GluR(121)
- Histamine(2)
- Histamine Receptor(238)
- mPEGS-1(4)
- Muscarinic Receptor(42)
- Neuroscience Peptides(47)
- Nicotinic Receptor(65)
- P2 Receptor(2)
- P2X7 receptor(3)
- SSRIs(7)
- Substance P/NK1 Receptor(20)
- NMDA(2)
- Cholecystokinin Receptor(24)
- GPR139(4)
- mAChR(145)
- MCHR1 (GPR24)(15)
- Neurokinin Receptor(63)
- iGluR(137)
- nAChR(70)
- Beta-secretase(25)
- CaMK(33)
- Dopamine Transporter(20)
- Monoamine Oxidase(91)
- Serotonin Transporter(57)
- Behavioral Neuroscience(372)
- DREADD(1)
- Huntington(17)
- Neuroendocrinology(65)
- Neuroprotection(128)
- Ophthalmology(168)
- Pain Research(241)
- Parkinson(78)
- Seizure Disorders(99)
- Prion(7)
- Cholinesterases(13)
- Huntingtin(0)
- AAK1(0)
- Tau Protein(4)
- Transthyretin (TTR)(0)
- α-synuclein(0)
- Neurodegenerative Disorders(7)
- Cholinesterase (ChE)(3)
- Amyloid-β(9)
- γ-secretase(1)
- Ischemia(3)
Products for Neuroscience
- Cat.No. Nom du produit Informations
-
GC49366
1-Salicylate Glucuronide
Salicyl Phenolic Glucuronide, Salicylic Acid Phenolic Glucuronide
A metabolite of salicylic acid and aspirin -
GC49088
1-Stearoyl-2-Adrenoyl-sn-glycero-3-PE
1-Octadecanoyl-2-Docosatetraenoyl-sn-glycero-3-Phosphatidylethanolamine, 1-Octadecanoyl-2-Docosatetraenoyl-sn-glycero-3-Phosphoethanolamine, 1-Octadecanoyl-2-Docosatetraenoyl-sn-glycero-3-PE, PE(18:0/22:4), 1-Stearoyl-2-Docosatraenoyl-sn-glycero-3-PE
A phospholipid -
GC42045
1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-PC
DHA-PC, 18:0/22:6 PC, PC(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)), 1-Stearoyl-2-Docosahexaenoyl-sn-glycero-3-Phosphatidylcholine, 1-Stearoyl-2-Docosahexaenoyl-sn-glycero-3-Phosphocholine
1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-PC is a phospholipid containing stearic acid and docosahexaenoic acid at the sn-1 and sn-2 positions, respectively. -
GC40176
1-Stearoyl-rac-glycerol
18:0-MG, MG(18:0/0:0/0:0), 1-Monostearin, NSC 3875
1-Stearoyl-rac-glycerol is a monoacylglycerol that contains stearic acid at the sn-1 position. -
GC49820
10,11-dihydro-10,11-dihydroxy Carbamazepine
10,11-dihydro-10,11-dihydroxy CBZ, CBZ-diol, Dihydroxycarbazepine, Dihydroxycarbamazepine
A metabolite of carbamazepine and oxcarbazepine -
GC13863
10Panx
10Panx
A peptide inhibitor of PANX1 -
GC46412
11β-Prostaglandin F2α-d4
9α,11βPGF2αd4, 11βPGF2αd4, 11epi PGF2αd4
An internal standard for the quantification of 11β-PGF F2α -
GC46413
11β-Prostaglandin F2α-d9
9α,11β-PGF2α-d9, 11β-PGF2α-d9, 11-epi PGF2α-d9
A neuropeptide with diverse biological activities -
GC18798
11-cis Retinal
11-cis Retinaldehyde, 11-cis Vitamin A aldehyde
11-cis Retinal is a chromophore that binds to opsin in the mammalian visual system as an inverse agonist forming the inactive conformation of rhodopsin.
-
GC48821
11-cis Retinol
11-cis Vitamin A Alcohol
An isomer of vitamin A -
GC18637
11β-Prostaglandin F2α
9α,11βPGF2α, 11βPGF2α, 11epi PGF2α
11β-Prostaglandin F2α (11β-PGF2α) is the primary plasma metabolite of PGD2 in vivo.
-
GC49808
12-methyl Tridecanoic Acid
iso-14:0, iso-C14:0, 12-MTA
A methylated fatty acid -
GC41892
13(R),14(R)-epoxy Fluprostenol isopropyl ester
Epoxy Derivative 1, 13(R),14(R)epoxy Travoprost
Fluprostenol isopropyl ester is a potent F-series prostaglandin receptor agonist prodrug that finds clinical use as an ocular hypotensive agent for the treatment of glaucoma. -
GC41894
13(S),14(S)-epoxy Fluprostenol isopropyl ester
Epoxy Derivative 2, 13(S),14(S)epoxy Travoprost
Fluprostenol isopropyl ester is a potent F-series prostaglandin receptor agonist prodrug that finds clinical use as an ocular hypotensive agent for the treatment of glaucoma. -
GC18783
13,14-dihydro-15-keto Prostaglandin E1
11α-Hydroxy-9,15-diketoprostanoic Acid, 15-keto-PGE0, 13,14-dihydro-15-keto PGE1, 15-keto-dihydro-PGE1, 15-keto Prostaglandin E0
13,14-dihydro-15-keto Prostaglandin E1 (PGE1) is a metabolite of PGE1 with much reduced biological activity. -
GC41910
13-Docosenamide
Armoslip E, cis13Docosenamide, Erucamide
13-Docosenamide is the amide of docosenoic acid. -
GC41907
13C C16 Sphingomyelin (d18:1/16:0)
Palmitoyl Sphingomyelin-13C, N-Palmitoyl-D-erythro-Sphingosylphosphorylcholine-13C, SM(d18:1/16:0-13C), Sphingomyelin (d18:1/16:0-13C)
13C C16 Sphingomyelin is an isotopically enriched form of C16 sphingomyelin with carbon-13 occurring on the fatty acid portion. -
GC41908
13C6 Glucosylsphingosine (d18:1)
1-β-D-Glucosyl-1,2,3,4,5,6-13C6-sphingosine, 13C6-Glucosylsphingosine
13C6 Glucosylsphingosine (d18:1) is an isotopically enriched form of 1-β-D-glucosylsphingosine (d18:1) that is intended for use as an internal standard for the quantification of 1-β-D-glucosylsphingosine by GC- or LC-MS. -
GC46437
14-dehydro Zymostenol
Δ8,14-Cholestandienol, Cholesta-8,14-dien-3β-ol
A cholesterol precursor -
GC40988
15(R)-17-phenyl trinor Prostaglandin F2α
15epi Bimatoprost (free acid), 15(R)Bimatoprost (free acid), 15(R)17phenyl trinor PGF2α
17-phenyl trinor Prostaglandin F2α N-ethyl amide (17-phenyl trinor PGF2α) is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name 17-phenyl trinor PGF2α ethyl amide. -
GC41922
15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester
15epi Bimatoprost isopropyl ester, 15(R)Bimatoprost isopropyl ester, 15(R)17phenyl trinor PGF2α isopropyl ester
15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester (15(R)-17-phenyl trinor PGF2α isopropyl ester) is the latanoprost-related isomer containing both a double bond at 13,14 and an inverted (β) hydroxyl group at C-15. -
GC41093
15(S)-Latanoprost
15epi Latanoprost
15(S)-Latanoprost is an analog of latanoprost in which the hydroxyl at carbon 15 is inverted relative to latanoprost. -
GC49036
15-(6-nitroxyhexanoyl)-17-phenyl trinor Prostaglandin F2α
15-(6-nitroxyhexanoyl)-17-phenyl trinor PGF2α, 15-(6-nitroxyhexanoyl)-Bimatoprost, NCX 470
A nitric oxide-donating derivative of 17-phenyl trinor prostaglandin F2α -
GC41932
15-keto Fluprostenol
Fluprostenol is an F-series prostaglandin analog which has been approved for many years as a luteolytic in veterinary animals.
-
GC41934
15-keto Latanoprost
Le 15-céto latanoprost est un métabolite du latanoprost, qui est un hypotenseur oculaire.
-
GC40989
15-keto Latanoprost (free acid)
15-keto Latanoprost is a potential metabolite of latanoprost when administered to animals.
-
GC41936
15-keto-17-phenyl trinor Prostaglandin F2α
15keto17phenyl trinor PGF2α
Bimatoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug. -
GC41937
15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide
15ketoBimatoprost, 17phenyl trinor PGF2α ethyl amide
Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide), an F-series PG analog which has been approved for use as an ocular hypotensive drug. -
GC41947
16-phenoxy tetranor Prostaglandin F2α cyclopropyl methyl amide
16phenoxy tetranor PGF2α cyclopropyl methyl amide
The actions of many clinical F-series prostaglandins (PGs), including those used for estrous synchronization and for reduction of intraocular pressure (IOP), are mediated through the PGF2α (FP) receptor. -
GC41948
16-phenoxy tetranor Prostaglandin F2α isopropyl ester
16phenoxy tetranor PGF2α isopropyl ester
Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. -
GC41949
16-phenoxy tetranor Prostaglandin F2α methyl amide
16phenoxy tetranor PGF2α methyl amide
Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. -
GC40961
16-phenoxy tetranor Prostaglandin F2α methyl ester
16phenoxy tetranor PGF2α
Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. -
GC46451
16F16
A PDI inhibitor
-
GC91109
17β-Estradiol 3-O-Sulfate (sodium salt)
Un métabolite inactif de 17β-estradiol.
-
GC41207
17(R)-HDHA
17(R)hydroxy Docosahexaenoic Acid, 17(R)HDoHE
Resolvins are a group of polyhydroxylated metabolites of docosahexaenoic acid (DHA) found in the inflammatory exudates of aspirin-treated experimental animals. -
GC41208
17(S)-HDHA
17(S)hydroxy Docosahexaenoic Acid, 17(S)HDoHE
17(S)-HDHA is a primary mono-oxygenation product of docosahexaenoic acid in human whole blood, human leukocytes, and mouse brain. -
GC46048
17(S)-HDHA-d5
17(S)-hydroxy Docosahexaenoic Acid-d5, 17(S)-HDoHE-d5
A neuropeptide with diverse biological activities -
GC17223
17-PA
Le 17-PA est un antagoniste sélectif de la potentialisation des neurostéroÏdes et de la synchronisation directe des récepteurs GABAA .
-
GC40962
17-phenoxy trinor Prostaglandin F2α
17phenoxy trinor PGF2α
17-phenoxy trinor prostaglandin F2α (17-phenoxy trinor PGF2α) is a novel analog of PGF2α. -
GC41960
17-phenoxy trinor Prostaglandin F2α ethyl amide
17phenoxy trinor PGF2α ethyl amide
Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. -
GC41961
17-phenoxy trinor Prostaglandin F2α isopropyl ester
17phenoxyPGF2α isopropyl ester
The actions of many clinical F-series prostaglandins (PGs), including those used for estrous synchronization and reduction of intraocular pressure (IOP), are mediated through the PGF2α (FP) receptor. -
GC40990
17-phenyl trinor Prostaglandin F2α
Bimatoprost (free acid), 17phenyl trinor PGF2α
17-phenyl trinor Prostaglandin F2α (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and is a potent agonist for the FP receptor. -
GC41291
17-phenyl trinor Prostaglandin F2α 1,15-lactone
Bimatoprost free acid 1,15 lactone, 17phenyl trinor PGF2α 1,15lactone
17-phenyl trinor Prostaglandin F2α (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α with potent FP receptor agonist activity and well known intraocular pressure-reducing effects. -
GC41967
17-phenyl trinor Prostaglandin F2α amide
Bimatoprost amide, 17phenyl trinor PGF2α amide
17-phényl trinor Prostaglandine F2α l'amide est un métabolite N-déséthylé du bimatoprost. -
GC41969
17-phenyl trinor Prostaglandin F2α cyclopropyl amide
Bimatoprost cyclopropyl amide, 17phenyl trinor PGF2α cyclopropyl amide
17-phenyl trinor Prostaglandin F2α cyclopropyl amide (17-phenyl trinor PGF2α cyclopropyl amide) is a novel analog of 17-phenyl trinor PGF2α ethyl amide. -
GC41970
17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide
17phenyl trinor PGF2α cyclopropyl methyl amide
Prostaglandin F2α (PGF2α) activates the FP receptor, promoting smooth muscle contraction and luteolysis. -
GC41971
17-phenyl trinor Prostaglandin F2α diethyl amide
Bimatoprost diethyl amide, 17phenyl trinor PGF2α diethyl amide, 17pPGF2αNEt2
17-phenyl trinor Prostaglandin F2α diethyl amide (17-phenyl trinor PGF2α diethyl amide) is an analog of PGF2α in which the C-1 carboxyl group has been modified to an N-diethyl amide. -
GC46458
17-phenyl trinor Prostaglandin F2α dimethyl amide
17-phenyl trinor PGF2α dimethyl amide, Bimatoprost dimethyl amide
An isomer of 17-phenyl trinor prostaglandin F2α ethyl amide -
GC46459
17-phenyl trinor Prostaglandin F2α ethyl amide-d4
Bimatoprost-d4, 15(S)-Bimatoprost-d4, 17-phenyl trinor PGF2α ethyl amide-d4
A neuropeptide with diverse biological activities -
GC46460
17-phenyl trinor Prostaglandin F2α glycinamide
17-phenyl trinor PGF2α glycinamide
A neuropeptide with diverse biological activities -
GC46461
17-phenyl trinor Prostaglandin F2α glycinamide methyl ester
17-phenyl trinor PGF2α glycinamide methyl ester
A neuropeptide with diverse biological activities -
GC46462
17-phenyl trinor Prostaglandin F2α isopropyl amide
17-phenyl trinor PGF2α isopropyl amide
A neuropeptide with diverse biological activities -
GC41972
17-phenyl trinor Prostaglandin F2α isopropyl ester
Bimatoprost isopropyl ester, 17phenyl trinor PGF2αiPr, 17phenyl trinor PGF2α isopropyl ester
17-phenyl trinor PGF2α N-ethyl amide is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name Bimatoprost. -
GC41973
17-phenyl trinor Prostaglandin F2α methyl amide
Bimatoprost methyl amide, Methylamido Dihydro Noralfaprostal, 17phenyl trinor PGF2α methyl amide
17-phenyl trinor Prostaglandin F2α (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and is a potent agonist for the FP receptor, binding with a relative potency of 756% compared to that of PGF2α. -
GC40392
17-phenyl trinor Prostaglandin F2α methyl ester
Bimatoprost methyl ester, 17phenyl trinor PGF2α methyl ester
17-phényl trinor Prostaglandine F2α l'ester méthylique est une prodrogue du bimatoprost. -
GC46463
17-phenyl trinor Prostaglandin F2α-d4
Bimatoprost (free acid)d4, 17phenyl trinor PGF2αd4
An internal standard for the quantification of bimatoprost (free acid) -
GC41975
17-trifluoromethylphenyl trinor Prostaglandin F2α
17trifluoromethylphenyl trinor PGF2α
A number of 17-phenyl trinor prostaglandin F2α (17-phenyl trinor PGF2α) derivatives have been approved for the treatment of glaucoma. -
GC41976
17-trifluoromethylphenyl trinor Prostaglandin F2α ethyl amide
17trifluoromethylphenyl trinor PGF2α ethyl amide
Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. -
GC41977
17-trifluoromethylphenyl trinor Prostaglandin F2α isopropyl ester
17trifluoromethylphenyl trinor PGF2α isopropyl ester
Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. -
GC41978
17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester
17trifluoromethylphenyl trinor PGF2α methyl ester
Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. -
GC46466
17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α
17trifluoromethylphenyl13,14dihydro trinor PGF2α
A prostaglandin F derivative similar to latanoprost free acid -
GC46478
1a-monohomo-17-phenyl trinor Prostaglandin F2α
1a-monohomo-17-phenyl trinor PGF2α
A neuropeptide with diverse biological activities -
GC90815
2',3'-cyclic NADP+ (sodium salt)
Un substrat pour CNP
-
GC70652
2'MeO6MF
2'MeO6MF est un modulateur allostérique positif de la pénétration cérébrale de α2β1γ2l et de tous les Récepteurs GABAA contenant α1.
-
GC49823
2′-C-β-Methylguanosine
An active nucleoside metabolite of BMS-986094
-
GC45321
2',3',5'-Triacetyluridine
-
GC60017
2'-O-Methylisoliquiritigenin
La 2'-O-méthylisoliquiritigénine, isolée de l'espèce Arachis, régule À la hausse les voies 5-HT, NE, DA et GABA, mais n'exerce pas d'effet très significatif sur la voie ne NE .
-
GC90517
2,2'-Bisnaloxone
Une impureté potentielle dans les préparations commerciales de naloxone.
-
GC42064
2,3-dinor Fluprostenol
Fluprostenol is a well-studied, potent analog of PGF2α acting primarily through the FP receptor.
-
GC90081
2,3-dinor-8-iso Prostaglandin F1α
Un métabolite actif de l'acide arachidonique et 8-iso PGF2α.
-
GC49671
2,3-Oxidosqualene
(3R,S)-Oxidosqualene, Squalene 2,3-oxide
An intermediate in the biosynthesis of sterols -
GC14752
2,4-Dihydroxyphenylacetyl-L-asparagine
glutamate receptors blocker
-
GC19695
2,8-Quinolinediol
-
GC49159
2-(1-Piperazinyl)pyrimidine
PmP, 1-PP, 1-(2-Pyrimidyl)piperazine
An α2-AR antagonist and active metabolite of azapirones -
GC46505
2-(Isopentylamino)naphthalene-1,4-dione
A vitamin K analog
-
GC17308
2-3-Pyridinedicarboxylic acid
-
GC49481
2-Aminotetralin
2-AT, Tetralin-2-amine
A neuromodulatory agent -
GC45773
2-chloro-N6-Cyclopentyladenosine (hydrate)
CCPA
A neuropeptide with diverse biological activities -
GC14873
2-CMDO
Dopamine D2-like receptor antagonist
-
GC40473
2-hydroxy Lignoceric Acid
Cerebronic Acid
2-hydroxy Lignoceric acid is an α-hydroxy very long chain fatty acid that is normally present in the mammalian nervous system. -
GC11267
2-Hydroxysaclofen
Le 2-hydroxysaclofène est un puissant antagoniste des récepteurs de l'acide γ-amino-butyrique-B (GABAB).
-
GC38108
2-Methyl-5-HT
La 2-méthyl-5-HT (2-méthyl-5-hydroxytryptamine) est un agoniste puissant et sélectif des récepteurs 5-HT3.
-
GC11176
2-Methyl-5-hydroxytryptamine hydrochloride
2-Methyl-5-hydroxytryptamine hydrochloride; 2-Methylserotonin hydrochloride; 2-Me-HT hydrochloride
Le chlorhydrate de 2-méthyl-5-hydroxytryptamine (chlorhydrate de 2-méthyl-5-hydroxytryptamine) est un agoniste puissant et sélectif des récepteurs 5-HT3. -
GC49840
2-Methylbutyrylglycine
2-MBG, N-sec-Valerylglycine
A metabolite of isoleucine -
GC52170
2-Nitroamino-2-imidazoline
NSC 25961, NSC 65424, NSC 91792
-
GC65195
2-O-Acetyl-20-hydroxyecdysone
β-Ecdysone 2-acetate
La 2-O-acétyl-20-hydroxyecdysone, une ecdystérone chez les insectes et les plantes terrestres, inhibe la cytotoxicité induite par l'amyloÏde-β42 (Aβ42). -
GC11001
2-Pyridylethylamine dihydrochloride
Histamine H1 receptor agonist
-
GC14959
2-[1-(4-Piperonyl)piperazinyl]benzothiazole
5-HT4 receptor
-
GC42085
20-hydroxy N-Arachidonoyl Taurine
Arachidonic acid is metabolized by cytochrome P450 (CYP450) 4A ω-hydroxylase to 20-HETE, which acts as a vasoconstrictor in the kidney and brain.
-
GC42087
21-desacetyl Deflazacort
L-6,485
21-desacetyl Deflazacort is the active glucocorticoid derived from the prodrug deflazacort. -
GC41210
22-HDHA
22-hydroxy Docosahexaenoic Acid, 22-OH DHA
22-HDHA is an oxidation product of docosahexaenoic acid. -
GC40571
24(S),25-epoxy Cholesterol
24(S)-24,25-EC
24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.
-
GC41614
24-dehydro Cholesterol
Desmosterol
Le 24-déhydrocholestérol est une molécule similaire au cholestérol.
-
GC46243
24-dehydro Cholesterol-d6
Desmosterol-d6
An internal standard for the quantification of 24-dehydro cholesterol -
GC33673
24-Hydroxycholesterol
Le 24-hydroxycholestérol est un stérol naturel, qui sert de modulateur allostérique positif des récepteurs R du N-méthyl-d-aspartate (NMDA) et d'un puissant activateur des facteurs de transcription LXR.
-
GC18171
25I-NBOMe (hydrochloride)
2C-I-NBOMe
A Certified Reference Material -
GC31021
2614W94
2614W94 est un inhibiteur sélectif et réversible de la monoamine oxydase-A avec un mécanisme d'inhibition compétitif et IC50 de 5 nM et Ki de 1,6 nM avec la sérotonine comme substrat.
-
GC39800
2BAct
2BAct est un activateur eIF2B (facteur d'initiation eucaryote 2B) hautement sélectif et actif par voie orale avec une CE50 de 33 nM.
-
GC15856
3'-Fluorobenzylspiperone maleate
ligand for the D2 receptor
-
GC15606
3α-Bis-(4-fluorophenyl) methoxytropane hydrochloride
dopamine uptake and transport inhibitor