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Home >> Signaling Pathways >> Immunology/Inflammation >> IκB/IKK

IκB/IKK

IKK (IκB kinase) is an enzyme complex that participates in NF-κB signaling pathway. It phosphorylates and inhibits IκB, thus leads to the activation of NF-κB. It is a target for treatment of inflammatory diseases and cancer.

Products for  IκB/IKK

  1. Cat.No. Product Name Information
  2. GC17416 ACHP IκB kinase inhibitor ACHP Chemical Structure
  3. GC31319 Amlexanox (AA673) Amlexanox (AA673) Chemical Structure
  4. GN10718 Andrographolide NF-κB signaling Inhibitor Andrographolide Chemical Structure
  5. GC10135 AZD3264 IKK2 inhibitor AZD3264 Chemical Structure
  6. GC10345 Bay 11-7085

    NK-κB activation inhibitor

     Bay 11-7085 Chemical Structure
  7. GC13035 Bay 11-7821

    IKK/NF-κB/TNFα inhibitor

     Bay 11-7821 Chemical Structure
  8. GC35474 Bay 65-1942 free base Bay 65-1942 free base Chemical Structure
  9. GC16303 Bay 65-1942 HCl salt IKKβ kinase inhibitor Bay 65-1942 HCl salt Chemical Structure
  10. GC35475 Bay 65-1942 R form Bay 65-1942 R form Chemical Structure
  11. GC60624 BAY-985 BAY-985 Chemical Structure
  12. GC18200 BI-605906 BI-605906 is an inhibitor of inhibitor of kappa B kinase subunit β (IKKβ; IC50 = 380 nM). BI-605906 Chemical Structure
  13. GC32028 BMS-066 BMS-066 Chemical Structure
  14. GC13926 BMS-345541(free base) IKK-1/IKK-2 inhibitor,potent and selective BMS-345541(free base) Chemical Structure
  15. GC12399 BMS345541 hydrochloride IKK inhibitor,highly selective BMS345541 hydrochloride Chemical Structure
  16. GC11573 BX795 PDK1 inhibitor BX795 Chemical Structure
  17. GC15083 Celastrol Antioxidant, anti-inflammatory and immunosuppressive agent Celastrol Chemical Structure
  18. GC11170 Choline Fenofibrate Choline salt of fenofibric acid Choline Fenofibrate Chemical Structure
  19. GC17873 CID-2858522 NF-κB pathway inhibitor CID-2858522 Chemical Structure
  20. GC16044 Emodin Naturally occurring anthraquinone,antiproliferative Emodin Chemical Structure
  21. GC33816 Ertiprotafib (PTP 112) Ertiprotafib (PTP 112) Chemical Structure
  22. GC43786 GS-143

    GS-143 is an inhibitor of IκBα ubiquitylation.

     GS-143 Chemical Structure
  23. GC62161 HOIPIN-1 HOIPIN-1 Chemical Structure
  24. GN10664 Honokiol Antioxidant/antitumor/antiangiogenic agent Honokiol Chemical Structure
  25. GC63007 HPN-01 HPN-01 Chemical Structure
  26. GC12370 IKK-16 (hydrochloride) IκB kinases (IKKs) inhibitor IKK-16 (hydrochloride) Chemical Structure
  27. GC12180 IKK-16 (IKK Inhibitor VII) Selective IκB kinase inhibitor IKK-16 (IKK Inhibitor VII) Chemical Structure
  28. GC11508 IKK-2 inhibitor VIII

    IKK-2 inhibitor,potent and selective

     IKK-2 inhibitor VIII Chemical Structure
  29. GC10592 IKK-3 Inhibitor IKK-3 Inhibitor IKK-3 Inhibitor Chemical Structure
  30. GC13278 IKKε-IN-1 potent IKKε inhibitor IKKε-IN-1 Chemical Structure
  31. GC17830 IMD 0354 IKKβ inhibitor IMD 0354 Chemical Structure
  32. GC33306 IMD-0560 IMD-0560 Chemical Structure
  33. GC34907 INH14 INH14 Chemical Structure
  34. GN10370 Luteolin Antioxidant and free radical scavenger Luteolin Chemical Structure
  35. GC10093 LY2409881 potent and selective IKK2 inhibitor LY2409881 Chemical Structure
  36. GC61021 Malachite green oxalate Malachite green oxalate Chemical Structure
  37. GC15942 ML 120B dihydrochloride IKK2-selective inhibitor ML 120B dihydrochloride Chemical Structure
  38. GC14989 MLN120B IκB Kinase β Inhibitor MLN120B Chemical Structure
  39. GC50093 MRT 68601 hydrochloride Potent TBK inhibitor MRT 68601 hydrochloride Chemical Structure
  40. GC17136 MRT67307 SIK/TBK-1/IKKe inhibitor MRT67307 Chemical Structure
  41. GC13184 PF 184 IKKβ inhibitor PF 184 Chemical Structure
  42. GN10503 Piceatannol p56lck/Syk inhibitor Piceatannol Chemical Structure
  43. GC12609 PS 1145 dihydrochloride IκB kinase (IKK) inhibitor PS 1145 dihydrochloride Chemical Structure
  44. GC17603 PS-1145 IKK inhibitor PS-1145 Chemical Structure
  45. GC11751 QNZ (EVP4593) Potent NF-κB inhibitor QNZ (EVP4593) Chemical Structure
  46. GC14553 Resveratrol A SIRT1 activator Resveratrol Chemical Structure
  47. GC12372 SC-514 ATP-competitive IKK-2 inhibitor, orally active SC-514 Chemical Structure
  48. GC10933 Sodium 4-Aminosalicylate NF-κB inhibitor Sodium 4-Aminosalicylate Chemical Structure
  49. GC12013 Sodium salicylate

    NF-κB inhibitor

     Sodium salicylate Chemical Structure
  50. GN10737 Tanshinone IIA Antioxidant and anti-inflammatory reagent Tanshinone IIA Chemical Structure
  51. GC37747 TBK1/IKKε-IN-1 TBK1/IKKε-IN-1 Chemical Structure
  52. GC63212 TBK1/IKKε-IN-4 TBK1/IKKε-IN-4 Chemical Structure
  53. GC17621 TPCA-1 IKK-2 inhibitor,potent and selective TPCA-1 Chemical Structure
  54. GC16658 Vinpocetine PDE inhibitor Vinpocetine Chemical Structure
  55. GN10269 Wedelolactone IKK inhibitor Wedelolactone Chemical Structure
  56. GC13384 WS6 inducer of β cell proliferation WS6 Chemical Structure

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