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Home >> Signaling Pathways >> Endocrinology and Hormones

Endocrinology and Hormones

Endocrinology and Hormones

Endocrinology and Hormones

The endocrine system is an information signaling system that coordinates most bodily functions. It senses environmental changes and secretes corresponding hormones to coordinate metabolism, maintain homeostasis, and regulate growth and development.read more

Targets for  Endocrinology and Hormones

Products for  Endocrinology and Hormones

  1. Cat.No. Product Name Information
  2. GC48328 Obestatin (human) (trifluoroacetate salt) A peptide hormone Obestatin (human) (trifluoroacetate salt) Chemical Structure
  3. GC44484 Obestatin (rat) (trifluoroacetate salt) Obestatin is a 23-amino acid peptide hormone that is formed by cleavage of the ghrelin and obestatin prepropeptide. Obestatin (rat) (trifluoroacetate salt) Chemical Structure
  4. GC14158 Obeticholic Acid A FXR agonist with anticholeretic activity Obeticholic Acid Chemical Structure
  5. GC11386 ODM-201 ODM-201 (ODM-201;BAY-1841788) is a potent androgen receptor (AR) antagonist with an IC50 of 26 nM in in vitro assay. ODM-201 Chemical Structure
  6. GN10457 Oleuropein

    A polyphenol

     Oleuropein Chemical Structure
  7. GC49815 Oleuropein aglycone A polyphenol with diverse biological activities Oleuropein aglycone Chemical Structure
  8. GC47824 Olmesartan Medoxomil-d6 An internal standard for the quantification of olmesartan medoxomil Olmesartan Medoxomil-d6 Chemical Structure
  9. GC32029 opigolix Opigolix is a Gonadotropin-releasing hormone (GnRH) receptor antagonist, used for the research of endometriosis and rheumatoid arthritis. opigolix Chemical Structure
  10. GC31250 Opioid receptor modulator 1

    Opioid receptor modulator 1 is a opioid receptor modulator extracted from patent WO2014072809A2, Compound RA11 in EXAMPLE 7.

     Opioid receptor modulator 1 Chemical Structure
  11. GC31127 ORL1 antagonist 1 ORL1 antagonist 1 is an opioid receptor-like 1 (ORL1) antagonist with an IC50 of 61 nM. ORL1 antagonist 1 Chemical Structure
  12. GC32402 ORM-15341 ORM-15341 is a potent and full antagonist for human AR (hAR) with IC50 values of 38 nM as shown by transactivation assays in AR-HEK293 cells stably expressing full-length hAR and an androgen-responsive luciferase reporter gene construct. ORM-15341 Chemical Structure
  13. GC16719 Ormeloxifene

    estrogen receptor modulator

     Ormeloxifene Chemical Structure
  14. GC11996 Ospemifene non-hormonal selective estrogen receptor modulator (SERM) Ospemifene Chemical Structure
  15. GC36820 Ostarine Ostarine Chemical Structure
  16. GC44527 p,p'-DDE p,p'-DDE is a metabolite and degradation product of the organochlorine pesticide DDT. p,p'-DDE Chemical Structure
  17. GC14304 Palovarotene

    Selective retinoic acid receptor gamma(RAR-γ) agonist

     Palovarotene Chemical Structure
  18. GP10069 Parathyroid hormone (1-34) (human) Parathyroid hormone (1-34) (human) Chemical Structure
  19. GC68337 Parathyroid hormone (1-34) (rat) acetate Parathyroid hormone (1-34) (rat) acetate Chemical Structure
  20. GP10106 Parathyroid Hormone (1-34), bovine Parathyroid Hormone (1-34), bovine Chemical Structure
  21. GC69654 Parathyroid Hormone (1-34), human, biotinylated

    Parathyroid Hormone (1-34), human, biotinylated is a probe for the parathyroid hormone receptor. It can be used to analyze the interaction between parathyroid hormone and its receptor in live cells, and purify the hormone-receptor complex through affinity chromatography.

     Parathyroid Hormone (1-34), human, biotinylated Chemical Structure
  22. GP10014 parathyroid hormone (7-34) [Homo sapiens]/[Macaca fascicularis]

    Enhancer of blood calcium level

     parathyroid hormone (7-34) [Homo sapiens]/[Macaca fascicularis] Chemical Structure
  23. GC47925 Pasireotide (aspartate) (trifluoroacetate salt) A somatostatin receptor agonist Pasireotide (aspartate) (trifluoroacetate salt) Chemical Structure
  24. GC32415 PCO371 PCO371 is an orally active full agonist of parathyroid hormone receptor 1 (PTHR1), with no effect on PTH type 2 receptor. PCO371 Chemical Structure
  25. GC44598 Peptide YY (human) (trifluoroacetate salt)

    Peptide YY (PYY) is a 36-amino acid peptide and anorectic gut hormone agonist for the neuropeptide Y receptors Y1, Y2, Y5, and Y6 with EC50 values of 0.7, 0.58, 1, and 0.8 nM, respectively, for supression of forskolin-induced cAMP accumulation.

     Peptide YY (human) (trifluoroacetate salt) Chemical Structure
  26. GP10131 Peptide YY(3-36), PYY, human Peptide YY(3-36), PYY, human Chemical Structure
  27. GC32107 Peretinoin (NIK333) Peretinoin (NIK333) is an oral acyclic retinoid with a vitamin A-like structure that targets retinoid nuclear receptors such as retinoid X receptor (RXR) and retinoic acid receptor (RAR). Peretinoin (NIK333) Chemical Structure
  28. GC15166 Perindopril Erbumine ACE inhibitor Perindopril Erbumine Chemical Structure
  29. GC50491 PF 04449913 maleate Potent Smo antagonist PF 04449913 maleate Chemical Structure
  30. GC12938 PF 998425 non-steroidal androgen receptor (AR) antagonist PF 998425 Chemical Structure
  31. GC44609 PF-1163A PF-1163A is a depsipeptide antifungal isolated from Penicillium that inhibits ergosterol synthesis (IC50 = 12 ng/ml). PF-1163A Chemical Structure
  32. GC11863 PHTPP estrogen ERβ receptor antagonist PHTPP Chemical Structure
  33. GC17433 Phytol activator of retinoid X receptors (RXRs) Phytol Chemical Structure
  34. GC10807 PL 017 Selective μ opioid receptor agonist PL 017 Chemical Structure
  35. GC44667 Ponasterone A Ponasterone A is an analog of 20-hydroxy ecdysone, the insect steroid hormone that regulates the metamorphosis of Drosophila. Ponasterone A Chemical Structure
  36. GC36947 Porcine dynorphin A(1-13) Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Porcine dynorphin A(1-13) Chemical Structure
  37. GC14370 PPT PPT (PPT) is a selective estrogen receptor alpha (ERα) agonist. The relative binding affinity of PPT for ERα (ERα: 49%) around 410 times higher compared with estrogen receptor beta (ERβ: 0.12%). PPT Chemical Structure
  38. GC44674 Pramlintide (acetate hydrate) Pramlintide is a non-amyloidogenic analog of the antidiabetic peptide hormone amylin that contains proline residues substituted at positions 25, 28, and 29. Pramlintide (acetate hydrate) Chemical Structure
  39. GC47969 Precocene II A chromene with anti-juvenile hormone activity Precocene II Chemical Structure
  40. GC44677 Prednicarbate Prednicarbate is a synthetic corticosteroid and a derivative of prednisolone. Prednicarbate Chemical Structure
  41. GC44679 Prednisone 21-aldehyde/22-hydroxy Prednisone Prednisone 21-aldehyde is a derivative of the synthetic corticosteroid prednisone that has antiviral activity against influenza virus A-PR8 in embryonated chicken eggs. Prednisone 21-aldehyde/22-hydroxy Prednisone Chemical Structure
  42. GC41266 Pregnanediol-3-Glucuronide A metabolite of progesterone Pregnanediol-3-Glucuronide Chemical Structure
  43. GC48724 Pregnanetriol A metabolite of 17α-hydroxyprogesterone Pregnanetriol Chemical Structure
  44. GC47973 PRGL493 An ACSL4 inhibitor PRGL493 Chemical Structure
  45. GC44686 Prochloraz Prochloraz is an imidazole antifungal that inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14α-demethylation of lanosterol, which results in disruption of the fungal cell membrane and cell death. Prochloraz Chemical Structure
  46. GC12408 Progesterone Progesterone Progesterone Chemical Structure
  47. GC47976 Progesterone-d9

    An internal standard for the quantification of progesterone

     Progesterone-d9 Chemical Structure
  48. GC47979 Propiconazole-d7 An internal standard for the quantification of propiconazole Propiconazole-d7 Chemical Structure
  49. GC47982 Propylthiouracil-d5 An internal standard for the quantification of propylthiouracil Propylthiouracil-d5 Chemical Structure
  50. GC36981 PROTAC AR Degrader-4 PROTAC AR Degrader-4 Chemical Structure
  51. GC61481 PROTAC AR Degrader-4 TFA PROTAC AR Degrader-4 TFA Chemical Structure
  52. GC34740 PROTAC RAR Degrader-1 PROTAC RAR Degrader-1 comprises a IAP ligand binding group, a linker and a RAR ligand binding group. PROTAC RAR Degrader-1 is an RAR degrader. Maximal RAR degradation at 30 μM concentration in HT1080 cells. Degradation inducers based on cIAP1 are called specific and non-genetic IAP-dependent protein erasers (SNIPERs). PROTAC RAR Degrader-1 Chemical Structure
  53. GC30588 Protirelin (Synthetic thyrotropin-releasing factor) Protirelin (Synthetic thyrotropin-releasing factor) is a highly conserved neuropeptide that exerts the hormonal control of thyroid-stimulating hormone (TSH) levels as well as neuromodulatory functions. Protirelin (Synthetic thyrotropin-releasing factor) Chemical Structure
  54. GC33845 Protirelin Acetate (TRF Acetate) Protirelin Acetate is a highly conserved neuropeptide that exerts the hormonal control of thyroid-stimulating hormone (TSH) levels as well as neuromodulatory functions. Protirelin Acetate (TRF Acetate) Chemical Structure
  55. GC33224 Proxalutamide (GT0918) Proxalutamide (GT0918) (GT0918) is an orally active potent androgen receptor (AR) antagonist. Proxalutamide (GT0918) (GT0918) can be used in the study for prostate cancer and COVID-19. Proxalutamide (GT0918) Chemical Structure
  56. GA23395 pTH (1-34) (rat) pTH (1-34) (rat) is a parathyroid hormone. pTH (1-34) (rat) Chemical Structure
  57. GC31395 PX20606 trans racemate (PX-102 trans racemate) PX20606 trans racemate (PX-102 trans racemate) (PX-102 trans racemate) is a FXR agonist with EC50s of 32 and 34 nM for FXR in FRET and M1H assay, respectively. PX20606 trans racemate (PX-102 trans racemate) Chemical Structure
  58. GC30771 PZM21 A µ-opioid receptor agonist PZM21 Chemical Structure
  59. GC12644 Quinestrol synthetic estrogen that is effective in hormone replacement therapy Quinestrol Chemical Structure
  60. GC49108 Racecadotril-d5 An internal standard for the quantification of racecadotril Racecadotril-d5 Chemical Structure
  61. GC19305 RAD140 RAD140 (RAD140) is a potent, orally active, nonsteroidal selective androgen receptor modulator (SARM) with a Ki of 7 nM. RAD140 Chemical Structure
  62. GC62683 Ralaniten Ralaniten (EPI-002) is a potent and orally active antagonist of the androgen receptor-N-terminal domain (AR-NTD). Ralaniten inhibits AR transcriptional activity, with IC50 of 7.4 μM. Ralaniten can be used for the research of castration-resistant prostate cancer (CRPC). Ralaniten Chemical Structure
  63. GC62603 Ralaniten triacetate Ralaniten triacetate (EPI-506), the pro-drug of Ralaniten, is a first-in-class, orally active androgen receptor (AR) N-terminal domain (NTD) inhibitor. Ralaniten triacetate shows activity against both full length and resistance-related AR species, including AR-v7. Ralaniten triacetate Chemical Structure
  64. GC25832 Raloxifene Raloxifene (Keoxifene, Pharoxifene, LY-139481, LY-156758, CCRIS-7129) is a second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. Raloxifene Chemical Structure
  65. GC13350 Raloxifene HCl Raloxifene HCl (Keoxifene hydrochloride) is a second generationselective and orally active estrogen receptor modulator. Raloxifene HCl Chemical Structure
  66. GC48023 Raloxifene-d4 (hydrochloride) An internal standard for the quantification of raloxifene Raloxifene-d4 (hydrochloride) Chemical Structure
  67. GC49653 Ramipril Diketopiperazine A potential impurity found in commercial preparations of ramipril Ramipril Diketopiperazine Chemical Structure
  68. GC49408 Ramipril Diketopiperazine Acid A potential impurity found in commercial preparations of ramipril Ramipril Diketopiperazine Acid Chemical Structure
  69. GC11957 RD162

    androgen receptor (AR) antagonist

     RD162 Chemical Structure
  70. GC32934 Relugolix (TAK-385) Relugolix (TAK-385) (TAK-385)is a potent, orally active, nonpeptidic gonadotropin-releasing hormone (GnRH) antagonist. Relugolix (TAK-385) Chemical Structure
  71. GC44812 Renin Fluorogenic Substrate The renin fluorogenic substrate consists of the normal peptide substrate for renin which has been linked to the fluorophore EDANS at one end and to a non-fluorescent quenching molecule (Dabcyl) at the other. Renin Fluorogenic Substrate Chemical Structure
  72. GC63402 Rezvilutamide Rezvilutamide (SHR3680) is an androgen receptor antagonist. Rezvilutamide (SHR3680) is used for the study of prostate cancer. Rezvilutamide Chemical Structure
  73. GC19448 RGX-104 RGX-104 is a small-molecule LXR agonist that modulates innate immunity via transcriptional activation of the ApoE gene. RGX-104 Chemical Structure
  74. GC37525 RGX-104 free Acid RGX-104 free Acid Chemical Structure
  75. GC66433 Ro 41-5253 Ro 41-5253 is an orally active selective retinoic acid receptor alpha (RARα) antagonist. Ro 41-5253 can bind RARα without inducing transcription or affecting RAR/RXR heterodimerization and DNA binding. Ro 41-5253 can inhibit cancer cell proliferation and induce apoptosis, has antitumor activity. Ro 41-5253 Chemical Structure
  76. GC38842 Ro 64-6198 Ro 64-6198 is a potent, selective, nonpeptide, high-affinity, high cellular permeability and brain penetration N/OFQ receptor (NOP) agonist with an EC50 value of 25.6 nM. Ro 64-6198 Chemical Structure
  77. GC15736 Rosuvastatin Calcium HMG-CoA reductase inhibitor Rosuvastatin Calcium Chemical Structure
  78. GC32054 Rovazolac Rovazolac is a liver x receptor (LXR) modulator extracted from patent WO2013130892A1. Rovazolac Chemical Structure
  79. GC17856 RU 58668 Pure antiestrogen that downregulates estrogen receptor expression RU 58668 Chemical Structure
  80. GC12933 RU 58841 A non-steroidal antiandrogen RU 58841 Chemical Structure
  81. GC44861 S-23 S-23 is a selective androgen receptor modulator (SARM). S-23 Chemical Structure
  82. GC50438 SAG dihydrochloride Dihydrochloride salt of SAG; Smo receptor agonist SAG dihydrochloride Chemical Structure
  83. GN10024 Saikosaponin A Saikosaponin A Chemical Structure
  84. GC13910 Salvinorin A Non-nitrogenous κ-opioid selective agonist Salvinorin A Chemical Structure
  85. GC18679 Salvinorin B

    Salvinorin B is an analytical reference standard categorized as a diterpene.

     Salvinorin B Chemical Structure
  86. GC49679 Sauvagine (trifluoroacetate salt) A neuropeptide hormone Sauvagine (trifluoroacetate salt) Chemical Structure
  87. GC13581 SB 205607 dihydrobromide non-peptide δ1 opioid receptor agonist SB 205607 dihydrobromide Chemical Structure
  88. GC39619 SB-612111 SB-612111 is a novel and potent opiate receptor-like orphan receptor (ORL-1) antagonist with a high affinity for hORL-1 (Ki=0.33 nM). SB-612111 Chemical Structure
  89. GC10011 SDM25N hydrochloride δ receptor antagonist SDM25N hydrochloride Chemical Structure
  90. GN10135 Sec-O-Glucosylhamaudol Sec-O-Glucosylhamaudol Chemical Structure
  91. GC48327 Secretin (rat) (trifluoroacetate salt) A neuropeptide hormone Secretin (rat) (trifluoroacetate salt) Chemical Structure
  92. GC48981 Senktide (trifluoroacetate salt) A potent NK3 receptor agonist Senktide (trifluoroacetate salt) Chemical Structure
  93. GC49592 Sermorelin (acetate) A growth hormone-releasing hormone analog Sermorelin (acetate) Chemical Structure
  94. GC37630 Sevelamer Sevelamer is a phosphate binding drug used to treat hyperphosphatemia in patients with chronic kidney disease; consists of polyallylamine that is crosslinked with epichlorohydrin. Sevelamer Chemical Structure
  95. GC11885 Sevelamer HCl Sevelamer HCl is a phosphate binding drug used to treat hyperphosphatemia in patients with chronic kidney disease; consists of polyallylamine that is crosslinked with epichlorohydrin. Sevelamer HCl Chemical Structure
  96. GC69883 sGnRH-A acetate

    sGnRH-A acetate is a salmon gonadotropin-releasing hormone (GnRH) analog. It can stimulate growth hormone secretion and can also be used as an artificial insemination ovulation inducer.

     sGnRH-A acetate Chemical Structure
  97. GN10213 Sinomenine Hydrochloride Sinomenine Hydrochloride Chemical Structure
  98. GC64600 SK33 SK33, a trifluoromethylated enobosarm analog, is a potent, and tissue selective anti-androgen. SK33reduces androgen receptor (AR) transcriptional activity. SK33 Chemical Structure
  99. GC12041 SNC 162 δ-opioid receptor agonist SNC 162 Chemical Structure
  100. GC11355 SNC 80 A δ-opioid agonist SNC 80 Chemical Structure
  101. GC12903 Sobetirome An agonist of TRβ Sobetirome Chemical Structure

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