Others

TDO-IN-1 is an orally active and selective inhibitor of tryptophan 2,3-dioxygenase (TDO), shows excellent selectivity over indoleamine-2,3-dioxygenase (IDO), with an IC50 value of 0.62 μM (IDO).

A2-Iso5-2DC18 is a didroimidazole-linked lipid, served as potent mRNA delivery vehicle.

NNMT-IN-4 (compound 38) is a selective, uncompetitive and membrane permeability nicotinamide N-metltransferase (NNMT) inhibitor with IC50 of 42 and 38 nM in vitro biochemical and cell-based assays, respectively.

FOXM1-IN-1 is a potent FOXM1 inhibitor with an IC50 value of 2.65 µM.

Anticancer agent 93 is a 4-droxycoumarin derivative.

JS6 is a Bcl3 inhibitor, and inhibits Bcl3-NF-kB1 binding.

(16R)-Epothilone D is the isomer of Epothilone D , and can be used as an experimental control.

Adrixetinib (TFA) is an inhibitor of protein tyrosine kinase with antineoplastic activity.

TNG-0746132 can be used for synthesis of the compound with anticancer activity.

Hi 76-0079 (Compound 31) is a hormone-sensitive lipase (HSL) inhibitor with an IC50 of 184 nM.

9-Amino-NeuAc is a substrate of synthase.

SOS1 agonist-1 (compound 79) is an agonist for the Son of sevenless homologue SOS1.

Ac-PLVE-FMK (Ac-Pro-Leu-Val-Glu(OMe)-CH2F), a tetrapeptidyl m-FMKs, is a Cats inhibitor.

JS11 is an inhibitor for natriuretic polypeptide receptor 1 (Npr1) with an IC50 of 1.9 μM for hNpr1.

NSC 194308, a U2AF2-RNA complexes enhancer, increases association of the U2AF1-U2AF2-SF1-splice site RNA complex by binding a site between the U2AF2 RNA recognition motifs (RRM1 and RRM2).

Sperm motility agonist-2 (compound 797) is a Sperm motility agonist.

PDS-0330 is a specific and potent Claudin-1 inhibitor.

Deruxtecan 2-droxypropanamide is a highly stable Deruxtecan analog that specifically binds to receptors highly expressed in tumor cells.

AGPS-IN-1 (Compound 2i) is an effective AGPS binder.

TCRS-417 (T417) is a small molecule compound capable of docking to the interface between PBX1 and its cognate DNA target sequence, effectively interfering with PBX1-DNA interaction.

FAP Ligand 1 (FL), a high-affinity FAP small-molecule ligand, is used to target attached drugs to FAP-expressing fibroblasts and can be used in radiation imaging studies of targeted cancers.

PAT1inh-B01 drocholide is a selective SLC26A6 inhibitor.

(9R, 12aR)-AZD4747 is a diastereomer of AZD4747.

S07-1066 is an aldo-keto reductase 1C3 (AKR1C3) inhibitor, synergizing doxorubicin (DOX) cytotoxicity.