Search Site
  • 0
    My Cart

    Click Here to Find How Many Items You Have Added:)

    image loader

    Adding item(s) to cart......

Home >> Signaling Pathways >> Ubiquitination/ Proteasome

Ubiquitination/ Proteasome

Products for  Ubiquitination/ Proteasome

  1. Cat.No. Product Name Information
  2. GC47445 Hydroxychloroquine-d4 (sulfate) An internal standard for the quantification of hydroxychloroquine Hydroxychloroquine-d4 (sulfate) Chemical Structure
  3. GC16843 Hydroxyurea DNA synthesis inhibitor Hydroxyurea Chemical Structure
  4. GN10278 Icariin

    Icariin is a flavonol glycoside.

     Icariin Chemical Structure
  5. GC38096 Icaritin Icaritin is a prenylflavonoid derivative obtained from the Epimedium genus. Icaritin Chemical Structure
  6. GC32762 Icaritin (Anhydroicaritin) Icaritin (Anhydroicaritin) (Anhydroicaritin) is a prenylflavonoid derivative from Epimedium brevicornuMaxim. and potently inhibits proliferation of K562 cells (IC50 of 8 μM) and primary CML cells (IC50 of 13.4 μM for CML-CP and 18 μM for CML-BC). Icaritin (Anhydroicaritin) can regulate MAPK/ERK/JNK and JAK2/STAT3 /AKT signalings, also enhances osteogenesis[3. Icaritin (Anhydroicaritin) Chemical Structure
  7. GC62626 ICCB-19 hydrochloride ICCB-19 hydrochloride is a TRADD (TNFRSF1A associated via death domain) inhibitor. ICCB-19 hydrochloride Chemical Structure
  8. GC14969 Idarubicin HCl Idarubicin HCl is an anthracycline antileukemic drug. Idarubicin HCl Chemical Structure
  9. GC62465 Idelalisib D5 Idelalisib D5 is a deuterium labeled Idelalisib. Idelalisib is a highly selective and orally bioavailable p110δ inhibitor. Idelalisib D5 Chemical Structure
  10. GC19411 IITZ-01 IITZ-01 is a potent lysosomotropic autophagy inhibitor with single-agent antitumor activity, with an IC50 of 2.62 μM for PI3Kγ. IITZ-01 Chemical Structure
  11. GC10314 Imatinib (STI571) Imatinib (STI571) (STI571) is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity. Imatinib (STI571) (STI571) works by binding close to the ATP binding site, locking it in a closed or self-inhibited conformation, therefore inhibiting the enzyme activity of the protein semicompetitively. Imatinib (STI571) also is an inhibitor of SARS-CoV and MERS-CoV. Imatinib (STI571) Chemical Structure
  12. GC60930 Imatinib D4 Imatinib D4 (STI571 D4) is a deuterium labeled Imatinib (STI571). Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity. Imatinib D4 Chemical Structure
  13. GC39612 Imatinib D8 Imatinib D8 (STI571 D8) is a deuterium labeled Imatinib (STI571). Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity. Imatinib D8 Chemical Structure
  14. GC11759 Imatinib Mesylate (STI571) Imatinib Mesylate (STI571) (STI571 Mesylate) is a tyrosine kinases inhibitor that inhibits c-Kit, Bcr-Abl, and PDGFR (IC50=100 nM) tyrosine kinases. Imatinib Mesylate (STI571) Chemical Structure
  15. GC10712 Imiquimod hydrochloride Toll-like receptor 7 agonist Imiquimod hydrochloride Chemical Structure
  16. GC12645 Imiquimod maleate Immune response modifier Imiquimod maleate Chemical Structure
  17. GC48614 IMP-1710 A clickable UCH-L1 inhibitor IMP-1710 Chemical Structure
  18. GC49670 Indium (III) thiosemicarbazone 5b An anticancer agent Indium (III) thiosemicarbazone 5b Chemical Structure
  19. GC17556 Indomethacin

    Indomethacin (Indometacin) is a potent, orally active COX1/2 inhibitor with IC50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively.

     Indomethacin Chemical Structure
  20. GC60935 Indomethacin sodium hydrate Indomethacin (Indometacin) sodium hydrateis a potent, orally active COX1/2 inhibitor with IC50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin sodium hydrate Chemical Structure
  21. GC40227 Indomethacin-d4 Indomethacin-d4 is intended for use as an internal standard for the quantification of indomethacin by GC- or LC-MS. Indomethacin-d4 Chemical Structure
  22. GC61565 Indophagolin Indophagolin is a potent, indoline-containing autophagy inhibitor (IC50=140 nM). Indophagolin antagonizes the purinergic receptor P2X4 as well as P2X1 and P2X3 with IC50s of 2.71, 2.40 and 3.49 μM, respectively. Indophagolin also antagonizes the Gq-protein-coupled P2Y4, P2Y6, and P2Y11 receptors (IC50s =3.4~15.4 μM). Indophagolin has a strong antagonistic effect on serotonin receptor 5-HT6 (IC50=1.0 μM) and a moderate effect on receptors 5-HT1B, 5-HT2B, 5-HT4e, and 5-HT7. Indophagolin Chemical Structure
  23. GC10969 INK 128(MLN0128) INK 128 (MLN0128) (INK-128; MLN0128; TAK-228) is an orally available, ATP-dependent mTOR1/2 inhibitor with an IC50 of 1 nM for mTOR kinase. INK 128(MLN0128) Chemical Structure
  24. GC32742 INT-767 INT-767 is a dual farnesoid X receptor (FXR)/TGR5 agonist with mean EC50s of 30 and 630 nM, respectively. INT-767 Chemical Structure
  25. GC16105 Iohexol contrast agent Iohexol Chemical Structure
  26. GC11229 IOWH-032 CFTR inhibitor IOWH-032 Chemical Structure
  27. GC30608 Ipsalazide

    Ipsalazide is a novel sulfasalazine analog designed to release 5-aminosalicylic acid and a nontoxic carrier molecule in the gastrointestinal tract.

     Ipsalazide Chemical Structure
  28. GC11473 Irinotecan Topoisomerase I inhibitor Irinotecan Chemical Structure
  29. GC11048 Irinotecan HCl Trihydrate Irinotecan HCl Trihydrate ((+)-Irinotecan HCl Trihydrate) is a topoisomerase I inhibitor with antitumor activity. Irinotecan HCl Trihydrate Chemical Structure
  30. GC36329 Irinotecan hydrochloride Irinotecan hydrochloride ((+)-Irinotecan hydrochloride) is a topoisomerase I inhibitor mainly used to treat colon cancer and rectal cancer. Irinotecan hydrochloride Chemical Structure
  31. GN10666 Isoalantolactone Isoalantolactone Chemical Structure
  32. GC13795 Isobavachalcone A chalcone and flavonoid with diverse biological activities Isobavachalcone Chemical Structure
  33. GC39109 Isodeoxyelephantopin Isodeoxyelephantopin is a sesquiterpene lactone isolated from Elephantopus scaber. Isodeoxyelephantopin induces ROS generation, suppresses NF-κB activation. Isodeoxyelephantopin also modulates LncRNA expression and exhibit activities against breast cancer. Isodeoxyelephantopin Chemical Structure
  34. GN10088 Isoliquiritigenin Isoliquiritigenin Chemical Structure
  35. GC12017 Isoniazid antibiotic used for the treatment of tuberculosis Isoniazid Chemical Structure
  36. GC64098 Isoniazid-d4 Isoniazid-d4 Chemical Structure
  37. GC36339 Isorhapontigenin Isorhapontigenin, an orally bioavailable dietary polyphenol isolated from the Chinese herb Gnetum cleistostachyum, displays anti-inflammatory effects. Isorhapontigenin Chemical Structure
  38. GC15826 Isosorbide Diuretic Isosorbide Chemical Structure
  39. GC36346 Isosorbide mononitrate A nitric oxide donor with cardioprotective activity Isosorbide mononitrate Chemical Structure
  40. GC15382 Isotretinoin A retinoid Isotretinoin Chemical Structure
  41. GC43922 Isovaleryl-L-carnitine (chloride) Isovaleryl-L-carnitine (chloride), a product of the catabolism of L-leucine, is a potent activator of the Ca2+-dependent proteinase (calpain) of human neutrophils. Isovaleryl-L-carnitine (chloride) Chemical Structure
  42. GC10447 Isradipine (Dynacirc) Isradipine (Dynacirc) (PN 200-110) is an orally active L-type calcium channel blocker. Isradipine (Dynacirc) Chemical Structure
  43. GC11056 Itraconazole antifungal agent Itraconazole Chemical Structure
  44. GC32209 ITX5061 ITX5061 is a type II inhibitor of p38 MAPK and also an antagonist of scavenger receptor B1 (SR-B1). ITX5061 Chemical Structure
  45. GC14797 IU1 A deubiquitinating enzyme inhibitor IU1 Chemical Structure
  46. GC10296 Ivacaftor (VX-770) Ivacaftor (VX-770) (VX-770) is a potent and orally bioavailable CFTR potentiator, targeting G551D-CFTR and F508del-CFTR with EC50s of 100 nM and 25 nM, respectively. Ivacaftor (VX-770) Chemical Structure
  47. GC12489 Ivacaftor benzenesulfonate A CFTR potentiator Ivacaftor benzenesulfonate Chemical Structure
  48. GC13316 Ivacaftor hydrate A CFTR potentiator Ivacaftor hydrate Chemical Structure
  49. GC12339 Ivermectin NAChR/purinergic P2X4 receptor modulator Ivermectin Chemical Structure
  50. GC36356 Ixazomib citrate Ixazomib citrate (MLN9708) is a reversible inhibitor of the chymotrypsin-like proteolytic β5 site of the 20S proteasome with an IC50 of 3.4 nM and a Ki of 0.93 nM. Ixazomib citrate Chemical Structure
  51. GC65331 IZCZ-3 IZCZ-3 is a potent c-MYC transcription inhibitor with antitumor activity. IZCZ-3 Chemical Structure
  52. GC10133 JNJ-42165279 FAAH inhibitor JNJ-42165279 Chemical Structure
  53. GC32690 JPH203 (KYT-0353)

    JPH203 (KYT-0353), a selective L-type amino acid transporter 1 inhibitor, significantly inhibited leucine uptake and cell growth in HT-29 YD-38 and leukemia cells, with IC50 values of 0.06 μM and 4.1 μM, respectively.

     JPH203 (KYT-0353) Chemical Structure
  54. GC19400 JPH203 Dihydrochloride JPH203 Dihydrochloride is a tyrosine analog, acts as a selective inhibitor of L-type amino acid transporter 1 (LAT1), and is used in cancer research. JPH203 Dihydrochloride Chemical Structure
  55. GC52272 Jun9-72-2 A SARS-CoV-2 PLpro inhibitor Jun9-72-2 Chemical Structure
  56. GC12693 JZL 195 Dual inhibitor of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) JZL 195 Chemical Structure
  57. GC11362 K 252a A protein kinase inhibitor K 252a Chemical Structure
  58. GC15730 Kaempferide A flavonoid with diverse biological activities Kaempferide Chemical Structure
  59. GC15684 KB-R7943 mesylate An inhibitor of the reverse Na+/Ca2+ exchanger KB-R7943 mesylate Chemical Structure
  60. GC12789 KC01 A selective inhibitor of ABHD16A KC01 Chemical Structure
  61. GC13023 KC02 Structural analog and inactive form of KC01 KC02 Chemical Structure
  62. GC14563 Ketanserin

    specific 5-HT2A serotonin receptor antagonist

     Ketanserin Chemical Structure
  63. GC43999 Ketanserin (tartrate) Ketanserin is a potent antagonist of the serotonin (5-HT) receptor that is selective for 5-HT2 (IC50 = 6.3 nM; Ki = 2.1 nM). Ketanserin (tartrate) Chemical Structure
  64. GC14413 KJ Pyr 9 c-Myc inhibitor, cell-permeable KJ Pyr 9 Chemical Structure
  65. GC14914 KM 11060 Corrects F508del-CFTR trafficking KM 11060 Chemical Structure
  66. GC14202 KN-62 Inhibitor of Ca2+/calmodulin-dependent kinase type II KN-62 Chemical Structure
  67. GC14132 KN-92 An inactive control compound for a CaMKII inhibitor KN-92 Chemical Structure
  68. GC15988 KN-92 hydrochloride An inactive control compound for a CaMKII inhibitor KN-92 hydrochloride Chemical Structure
  69. GC16981 KN-92 phosphate KN-92 phosphate Chemical Structure
  70. GC10629 KN-93 Selective inhibitor of Ca2+/calmodulin-dependent kinase type II KN-93 Chemical Structure
  71. GC12501 KN-93 hydrochloride CaMK II inhibitor KN-93 hydrochloride Chemical Structure
  72. GC12804 KN-93 Phosphate CaM kinase II inhibitor, water soluble and cell permeable KN-93 Phosphate Chemical Structure
  73. GC33377 KSI-3716 KSI-3716 is a potent c-Myc inhibitor that blocks c-MYC/MAX binding to target gene promoters. KSI-3716 is an effective intravesical chemotherapy agent for bladder cancer. KSI-3716 Chemical Structure
  74. GC11118 KU 55933 An ATM kinase inhibitor KU 55933 Chemical Structure
  75. GC31899 KZR-504 KZR-504 is a highly selective inhibitor of immunoproteasome low molecular mass polypeptide 2 (LMP2), with IC50s of 51 nM, 4.274 μM for LMP2 and LMP7, respectively. KZR-504 Chemical Structure
  76. GC15924 L-779,450 Raf kinase inhibitor L-779,450 Chemical Structure
  77. GC40793 L-erythro Sphinganine (d18:0) L-erythro Sphinganine (d18:0) is a synthetic bioactive sphingolipid and stereoisomer of sphinganine (d18:0) and D-threo sphinganine. L-erythro Sphinganine (d18:0) Chemical Structure
  78. GC13123 Lactacystin (Synthetic)

    A selective inhibitor of the 20S proteasome

     Lactacystin (Synthetic) Chemical Structure
  79. GC14764 Lamotrigine 5-HT inhibitor， sodium channel blocker Lamotrigine Chemical Structure
  80. GC64113 Lamotrigine-13C3,d3 Lamotrigine-13C3,d3 Chemical Structure
  81. GC32468 Lanatoside C Lanatoside C is a cardiac glycoside, can be used in the treatment of congestive heart failure and cardiac arrhythmia. Lanatoside C Chemical Structure
  82. GC15114 LAQ824 (NVP-LAQ824,Dacinostat) A hydroxamate-based HDAC inhibitor LAQ824 (NVP-LAQ824,Dacinostat) Chemical Structure
  83. GC17768 Lasalocid ionophore antibiotic Lasalocid Chemical Structure
  84. GC36427 Lasalocid sodium Lasalocid sodium (Lasalocid-A sodium) treatment led to an increase in cell wall thickness, whilst the quantity and sugar composition of the cell wall remained unchanged in BY-2 cells. Lasalocid sodium Chemical Structure
  85. GC17974 Latrepirdine dihydrochloride Latrepirdine is a neuroactive compound with antagonist activity at histaminergic, α-adrenergic, and serotonergic receptors. Latrepirdine dihydrochloride Chemical Structure
  86. GC39395 LC3-mHTT-IN-AN1 LC3-mHTT-IN-AN1 (Compound AN1) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN1 Chemical Structure
  87. GC39313 LC3-mHTT-IN-AN2 LC3-mHTT-IN-AN2 (Compound AN2) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN2 Chemical Structure
  88. GC10510 LDN 57444 An inhibitor of UCH-L1 LDN 57444 Chemical Structure
  89. GN10768 Leonurine hydrochloride Leonurine hydrochloride Chemical Structure
  90. GC10726 Letrozole Non-steroidal aromatase inhibitor Letrozole Chemical Structure
  91. GC15929 Levosimendan calcium sensitiser Levosimendan Chemical Structure
  92. GC44059 LG 100268 LG 100268 is an agonist of retinoid X receptors (RXRs; Kd = 3 nM). LG 100268 Chemical Structure
  93. GC34173 LG-100064 LG-100064 is a retinoid-X-receptor (RXR) agonist, with EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ; LG-100064 can be used in the research of cancer. LG-100064 Chemical Structure
  94. GN10036 Licochalcone A Licochalcone A Chemical Structure
  95. GC36447 Licochalcone E Licochalcone E, a flavonoid compound isolated from Glycyrrhiza inflate, inhibits NF-κB and AP-1 transcriptional activity through the inhibition of AKT and MAPK activation. Licochalcone E Chemical Structure
  96. GC38150 Liensinine Diperchlorate Liensinine Diperchlor?ate is a major isoquinoline alkaloid, extracted from the seed embryo of Nelumbo nucifera Gaertn. Liensinine Diperchlorate Chemical Structure
  97. GC64325 Ligustilide Ligustilide is is a bioactive phthalide derivative isolated from Angelica sinensis and Chuanxiong. Ligustilide Chemical Structure
  98. GC14827 Linagliptin (BI-1356) A potent DPP-4 inhibitor Linagliptin (BI-1356) Chemical Structure
  99. GC17958 Linifanib (ABT-869) Linifanib (ABT-869) (ABT-869) is a potent and orally active multi-target inhibitor of VEGFR and PDGFR family with IC50s of 4, 3, 66, and 4 nM for KDR, FLT1, PDGFRβ, and FLT3, respectively. Linifanib (ABT-869) shows prominent antitumor activity. Linifanib (ABT-869) has much less activity against unrelated RTKs, soluble tyrosine kinases, or serine/threonine kinases. Linifanib (ABT-869) is a specific miR-10b inhibitor that blocks miR-10b biogenesis. Linifanib (ABT-869) Chemical Structure
  100. GC17057 Lithocholic Acid Activator of vitamin D receptor,PXR and FXR Lithocholic Acid Chemical Structure
  101. GC34649 LMP7-IN-1 LMP7-IN-1 is an orally bioavailable, potent, reversible and highly selective immunoproteasome subunit LMP7 (β5i) inhibitor. LMP7-IN-1 exerts high biochemical (IC50=3.6 nM) and cellular (IC50=3.4 nM) potency against the LMP7 subunit. LMP7-IN-1 shows strong antitumor efficacy in multiple myeloma xenograft models. LMP7-IN-1 leads to a significant and prolonged suppression of tumor LMP7 activity and ubiquitinated protein turnover and the induction of apoptosis in multiple myeloma cells. LMP7-IN-1 Chemical Structure

Items 501 to 600 of 1179 total

per page
  2. 4
  3. 5
  4. 6
  5. 7
  6. 8

Set Descending Direction