Membrane Transporter/Ion Channel
Research Areas
- AMPAR(55)
- Aquaporins(3)
- Piezo Channels(6)
- ATPase(79)
- Calcium Channel(352)
- Cannabinoid Transporters(6)
- CFTR(51)
- Chloride Channels(12)
- GABA Receptor(202)
- Glucose Transporters(17)
- Glutamate (EAAT) Transporters(18)
- Glycine Receptors(2)
- GlyT(19)
- GTPase(30)
- ICB(1)
- MCT2(2)
- Monoamine transporter(16)
- Monocarboxylate Transporters(14)
- Multidrug Transporters(4)
- Na+/Ca2+ Exchanger(16)
- NKCC(9)
- NMDA Receptor(77)
- Nucleoside Transporters(6)
- Pannexin-1(2)
- P2X purinergic receptor(70)
- P-gp(10)
- Proton Pump(59)
- Potassium Channel(333)
- Sodium Channel(224)
- TRP Channel(188)
- TRPV1(10)
- URAT1(14)
- Other Channel Modulators(10)
- MCT(3)
- Kainate Receptors(11)
- Ionophore(3)
- sodium-hydrogen exchanger(3)
- Chloride Channel(31)
- CRAC Channel(14)
- EAAT2(6)
- HCN Channel(9)
- Na+/HCO3- Cotransporter(1)
- Na+/K+ ATPase(30)
- P-glycoprotein(59)
- iGluR(179)
- nAChR(119)
- VDAC(3)
- GlyR(1)
- Ferroportin(4)
- Urea Transporter(1)
- Na+/H+ Exchanger (NHE)(2)
- NTPDase(4)
- EAAT(5)
- ASCT(3)
- Apical Sodium-Dependent Bile Acid Transporter(1)
- Sec61(2)
- ATP-binding cassette (ABC) transporters(5)
- SLC39 (Zinc Transporter)(2)
- Sodium Phosphate Cotransporter(1)
Products Related to Membrane Transporter/Ion Channel(2415)
- GC83181Hexadecylphosphoserine TFAPurity: >98.00%
Hexadecylphosphoserine TFA is a phospholipid molecule that contains a long-chain alkyl (hexadecyl) and a phosphoserine group, giving it a high affinity for the cell membrane.
- GC83262IndenebartCAS: 2864437-88-5Purity: >99.50%
is an SNCA -targeting IgG1λ2 type human antibody, the recommed isotype control is Human IgG1 lambda2, Isotype Control [1] .
- GC83293Ivacaftor-d 9CAS: 1413431-07-8Purity: >99.50%
Ivacaftor-d 9 is a potent CFTR modulator and exhibits an EC 50 value of 255 nM for CFTR potentiation in G551D/F508del HBE Cells.
- GC83329KCC2 Modulator-2CAS: 2704531-37-1Purity: >99.50%
KCC2 Modulator-2 (example 53) is a KCC2 modulator with an EC 50 of 0.215 μM.
- GC83330KCC2 potentiators-1CAS: 3058906-46-7Purity: >97.00%
KCC2 potentiators-1 is a KCC2 potentiator with an EC 50 of less than 0.1 μM in NG-108 cells.
- GC83360L-Glutamic acid- 13 C 5 , 15 N,d 5CAS: 1420815-74-2Purity: >99.00%
L-Glutamic acid- 13 C 5, 15 N,d 5 is the deuterium, 13 C-, and 15-labeled L-Glutamic acid.
- GC83374L-Palmitoylcarnitine-d 9CAS: 2847775-90-8Purity: >99.00%
L-Palmitoylcarnitine-d 9 is deuterium labeled L-Palmitoylcarnitine.
- GC83375L-Phenylalanine-d 7CAS: 69113-60-6Purity: >99.50%
L-Phenylalanine-d 7 is the deuterium labeled L-Phenylalanine.
- GC83390LaniquidarCAS: 197509-46-9Purity: >98.50%
Laniquidar is a non-competitive P-gp inhibitor with an IC 50 of 0.51 μM.
- GC83396LaventatugCAS: 3009829-91-5Purity: >95.50%
Laventatug (BRY-812 Antibody) is a humanized IgG1-kappa monoclonal antibody targeting hSLC39A6.
- GC83414Lidocaine-d 6 hydrochlorideCAS: 2517378-96-8Purity: >98.00%
Lidocaine-d 6 (hydrochloride) is deuterium labeled Lidocaine (hydrochloride).
- GC83450LY 303511 hydrochlorideCAS: 2070014-90-1Purity: >98.50%
LY 303511 hydrochloride is a structural analogue of LY294002.
- GC83563MexiletineCAS: 31828-71-4Purity: >99.50%
Mexiletine is an orally effective antiarrhythmic agent which has also been found to be effective for myotonia and neuropathic pain.
- GC83579(-)-KCC2 blocker 1CAS: 1228439-73-3Purity: >99.00%
(-)-KCC2 blocker 1 is an enantiomer of KCC2 blocker 1.
- GC83608Moxidectin-d 3Purity: >95.00%
Moxidectin-d 3 (CL-301423-d 3 ) is deuterium labeled Moxidectin.
- GA10750L-Glutamic acidCAS: 56-86-0Purity: >99.00%
L-Glutamic acid is the main excitatory neurotransmitter in the mammalian central nervous system (CNS). L-Glutamic acid has two major types of receptors: ionotropic (NMDA-, AMPA-, and kainate-selective iGluRs) and metabotropic glutamate receptors. L-Glutamic acid induces excitotoxicity by activating the postsynaptic N-methyl-D-aspartate receptors, leading to neurodegenerative diseases.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC83181 | Hexadecylphosphoserine TFA | - | >98.00% | |
Hexadecylphosphoserine TFA is a phospholipid molecule that contains a long-chain alkyl (hexadecyl) and a phosphoserine group, giving it a high affinity for the cell membrane. | ||||
| GC83216 | HYL001 | 2426547-83-1 | >99.50% | |
HYL001 is an orally active, selective ALK4/ALK5 inhibitor with K d values of 13 nM and 22.5 nM for ALK4 and ALK5, respectively. | ||||
| GC83262 | Indenebart | 2864437-88-5 | >99.50% | |
is an SNCA -targeting IgG1λ2 type human antibody, the recommed isotype control is Human IgG1 lambda2, Isotype Control [1] . | ||||
| GC83273 | IP3RCYT | - | >95.50% | |
IP3RCYT is an IP 3 R inhibitory peptide, which can inhibit the binding of cytochrome C to IP 3 R with an IC 50 about 100 nM. | ||||
| GC83275 | IP3RPEP6 | 3061802-23-8 | >98.00% | |
IP3RPEP6 is an IP 3 R competitive inhibitor. | ||||
| GC83293 | Ivacaftor-d 9 | 1413431-07-8 | >99.50% | |
Ivacaftor-d 9 is a potent CFTR modulator and exhibits an EC 50 value of 255 nM for CFTR potentiation in G551D/F508del HBE Cells. | ||||
| GC83324 | JW-65 | 2763378-71-6 | >99.00% | |
JW-65 is a selective TRPC3 channel inhibitor with favorable blood-brain barrier penetration. | ||||
| GC83329 | KCC2 Modulator-2 | 2704531-37-1 | >99.50% | |
KCC2 Modulator-2 (example 53) is a KCC2 modulator with an EC 50 of 0.215 μM. | ||||
| GC83330 | KCC2 potentiators-1 | 3058906-46-7 | >97.00% | |
KCC2 potentiators-1 is a KCC2 potentiator with an EC 50 of less than 0.1 μM in NG-108 cells. | ||||
| GC83360 | L-Glutamic acid- 13 C 5 , 15 N,d 5 | 1420815-74-2 | >99.00% | |
L-Glutamic acid- 13 C 5, 15 N,d 5 is the deuterium, 13 C-, and 15-labeled L-Glutamic acid. | ||||
| GC83374 | L-Palmitoylcarnitine-d 9 | 2847775-90-8 | >99.00% | |
L-Palmitoylcarnitine-d 9 is deuterium labeled L-Palmitoylcarnitine. | ||||
| GC83375 | L-Phenylalanine-d 7 | 69113-60-6 | >99.50% | |
L-Phenylalanine-d 7 is the deuterium labeled L-Phenylalanine. | ||||
| GC83390 | Laniquidar | 197509-46-9 | >98.50% | |
Laniquidar is a non-competitive P-gp inhibitor with an IC 50 of 0.51 μM. | ||||
| GC83396 | Laventatug | 3009829-91-5 | >95.50% | |
Laventatug (BRY-812 Antibody) is a humanized IgG1-kappa monoclonal antibody targeting hSLC39A6. | ||||
| GC83414 | Lidocaine-d 6 hydrochloride | 2517378-96-8 | >98.00% | |
Lidocaine-d 6 (hydrochloride) is deuterium labeled Lidocaine (hydrochloride). | ||||
| GC83445 | Lupanine | 550-90-3 | >98.00% | |
Lupanine (D-Lupanine) is a natural ketonic derivative of Sparteine with a ganglioplegic activity. | ||||
| GC83450 | LY 303511 hydrochloride | 2070014-90-1 | >98.50% | |
LY 303511 hydrochloride is a structural analogue of LY294002. | ||||
| GC83538 | Menthol-d 4 | 1217765-02-0 | >98.00% | |
Menthol-d 4 is the deuterium labeled Menthol. | ||||
| GC83546 | Methionine-d 4 | - | >98.00% | |
Methionine-d 4 is the deuterium labeled Methionine. | ||||
| GC83563 | Mexiletine | 31828-71-4 | >99.50% | |
Mexiletine is an orally effective antiarrhythmic agent which has also been found to be effective for myotonia and neuropathic pain. | ||||
| GC83579 | (-)-KCC2 blocker 1 | 1228439-73-3 | >99.00% | |
(-)-KCC2 blocker 1 is an enantiomer of KCC2 blocker 1. | ||||
| GC83608 | Moxidectin-d 3 | - | >95.00% | |
Moxidectin-d 3 (CL-301423-d 3 ) is deuterium labeled Moxidectin. | ||||
| GA10299 | H-Phe-OH | 63-91-2 | >99.00% | |
| GA10750 | L-Glutamic acid | 56-86-0 | >99.00% | |
L-Glutamic acid is the main excitatory neurotransmitter in the mammalian central nervous system (CNS). L-Glutamic acid has two major types of receptors: ionotropic (NMDA-, AMPA-, and kainate-selective iGluRs) and metabotropic glutamate receptors. L-Glutamic acid induces excitotoxicity by activating the postsynaptic N-methyl-D-aspartate receptors, leading to neurodegenerative diseases. | ||||