Metabolism
- Sterol Biosynthesis(26)
- PPAR(216)
- 5-alpha Reductase(9)
- 5-Lipoxygenase(11)
- Adenosine Deaminase(8)
- Aminopeptidase(10)
- C14ɑ demethylase(2)
- Carbonic Anhydrase(63)
- CETP(13)
- Cholesterol absorption(1)
- CPT1(3)
- CYP3A/CYP450(26)
- Dehydrogenase(139)
- DHFR(11)
- DGAT(13)
- Dopamine β-hydroxylase(14)
- Enolase(11)
- FAAH(40)
- Factor Xa(49)
- Ferroptosis(200)
- Folate Analogue(3)
- Glucokinase(17)
- HLE(1)
- HMG-CoA Reductase(39)
- HSP(77)
- IDO(52)
- KRAS-PDEδ(4)
- MAO(9)
- Metabolic Enzymes(0)
- Neuronal Metabolism(8)
- Oxidative Phosphorylation(17)
- P450(146)
- PDE(254)
- Phospholipase(117)
- Procollagen C Proteinase(2)
- Saccharometabolism(1)
- SCD(19)
- SGLT(31)
- TPH(6)
- Transferase(183)
- Energy Metabolism(0)
- Inorganic Ions(0)
- ALP(1)
- Carbohydrates(18)
- Uric Acid(0)
- Muscle Metabolism(0)
- MDA(0)
- MPO(0)
- Transaminase(20)
- Glutathione Reductase(0)
- Thioredoxin Reductase(0)
- Catalase(8)
- monooxygenase(1)
- PKM2(1)
- aldehyde dehydrogenase(1)
- Squalene synthase(1)
- Hydrolase(47)
- ornithine decarboxylase(1)
- Amino acid metabolism(3)
- phosphatases(98)
- Pyruvate kinase(9)
- Others(4)
- MGL(1)
- Galactosidase(6)
- 12-Lipoxygenase(1)
- Fatty Acid Synthase (FASN)(9)
- Dihydroorotate Dehydrogenase(12)
- Bile Acids & Microbiome(94)
- Bone Growth & Remodeling(35)
- Carbohydrate Metabolism(126)
- Cofactors & Vitamins(64)
- Dyslipidemias(73)
- Inborn Errors of Metabolism(80)
- Metabolic Syndrome(16)
- Necroptosis(10)
- Necrosis(15)
- Nutrient Sensing(12)
- Phosphodiesterase(27)
- Reproductive Biology(126)
- Thermogenesis(6)
- Prolyl Hydroxylation Enzymes(1)
- Biliary System(4)
- Metabolic Disease(4)
- Fat Mass and Obesity-associated Protein (FTO)(2)
- SHIP(1)
Produkte für Metabolism
- Bestell-Nr. Artikelname Informationen
- GC49326 5β-Dihydroprogesterone A progesterone receptor agonist and metabolite of progesterone
- GC49176 5β-Tetrahydrocortisol An endogenous metabolite of cortisol
- GC18582 5'-hydroxy Meloxicam A metabolite of meloxicam
- GC49499 5(Z)-Dodecenoic Acid 5(Z)-DodecensÄure ist ein endogener Metabolit mit hemmenden AktivitÄten gegen COX-I und COX-II.
-
GC18542
5,6-dihydro-5-Fluorouracil
5,6-dihydro-5-Fluorouracil (5-FUH2) is formed by the hydrogenation of 5-fluorouracil via the enzyme dihydropyrimidine dehydrogenase (DPD).
- GC18466 5,6-epoxy-13-cis Retinoic Acid 5,6-epoxy-13-cis Retinoic acid is a metabolite of 13-cis retinoic acid.
- GC13319 5,8,11-Eicosatriynoic Acid nonselective inhibitor of lipoxygenases (12-LO)
- GC52227 5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone An active metabolite of various polyphenols
- GC63358 5-Aminosalicylic Acid-D3 hydrochloride
- GC52413 5-Aminosalicylic Acid-d7 An internal standard for the quantification of 5-aminosalicylic acid
- GC49827 5-Androstenetriol An active metabolite of DHEA
- GC49877 5-bromo-3-indolyl-β-D-Galactopyranoside 5-Brom-3-indolyl-β-D-Galactopyranosid (Bluo-Gal) ist ein chromogenes Substrat zum Nachweis bakterieller β-D-Galactosidase-AktivitÄt.
- GC49655 5-hydroxy Buspirone A metabolite of buspirone
- GC42546 5-hydroxy Diclofenac 5-hydroxy Diclofenac is a metabolite of the NSAID diclofenac formed by the cytochrome P450 (CYP) isoform CYP3A4.
- GC49119 5-hydroxy Flunixin A metabolite of flunixin
- GC49315 5-hydroxy Indomethacin A metabolite of indomethacin
-
GC41312
5-hydroxy Omeprazole
5-hydroxy Omeprazole is a major metabolite of omeprazole, an inhibitor of the gastric H+/K+-ATPase pump.
- GC12829 5-hydroxy Tryptophol 5-Hydroxy-Tryptophol ist ein Serotonin-Metabolit von Säugetieren, der als Marker für akuten Alkoholkonsum dient.
- GC42550 5-hydroxy-6-methoxy (S)-Duloxetine 5-hydroxy-6-methoxy (S)-Duloxetine is a metabolite of (S)-duloxetine.
- GC42551 5-hydroxymethyl Tolterodine (formate) 5-hydroxymethyl Tolterodine is an active metabolite of the muscarinic acetylcholine receptor antagonists tolterodine and fesoterodine.
- GN10241 5-Methoxypsoralen
- GC46706 5-Methyltetrahydrofolic Acid (hydrate) A biologically active form of folic acid
- GC41310 5-Octyl-α-ketoglutarate In addition to its role in the Krebs cycle, α-ketoglutarate (2-oxoglutarate) has roles as a substrate or modulator of enzymes.
- GC46713 5-Phospho-D-ribose 1-diphosphate (sodium salt hydrate) An intermediate in several biochemical pathways
- GC11101 5-R-Rivaroxaban
- GC42586 6α-hydroxy Paclitaxel 6α-Hydroxy Paclitaxel ist ein primÄrer Metabolit von Paclitaxel. 6α-hydroxy Paclitaxel behÄlt eine zeitabhÄngige Wirkung auf die organischen Anionen-transportierenden Polypeptide 1B1/SLCO1B1 (OATP1B1) mit Ähnlicher Hemmkraft wie Paclitaxel, wÄhrend es keine zeitabhÄngige Hemmung von OATP1B3 mehr zeigte. 6α-Hydroxy-Paclitaxel kann fÜr die Krebsforschung verwendet werden.
- GC49676 6β-hydroxy Budesonide A metabolite of budesonide
- GC45969 6β-hydroxy Eplerenone A major metabolite of eplerenone
- GC49629 6β-hydroxy Prednisolone A metabolite of prednisolone
- GC19536 6'-Sialyllactose Sodium Salt 6'-Sialyllactose (Natrium), ein vorherrschendes Milch-Oligosaccharid, reduziert die Internalisierung von Pseudomonas aeruginosa in menschliche Pneumozyten.
- GC52056 6(Z),9(Z),12(Z),15(Z)-Hexadecatetraenoic Acid ethyl ester 6(Z),9(Z),12(Z),15(Z)-HexadecatetraensÄureethylester ist ein oral wirksames n-1PUFA.
- GC11864 6,7-dihydroxy Bergamottin potent inhibitor of CYP3A4
- GC10868 6,7-Dimethyltetrahydropterin (hydrochloride) GTP cyclohydrolase I inhibitor
- GC10462 6-Aminonicotinamide 6-Aminonicotinamid, ein potenter Antimetabolit von Nicotinamid, ist ein kompetitiver NADP+--abhÄngiger Hemmer des Enzyms Glucose-6-Phosphat-Dehydrogenase (G6PD) (Ki=0,46 μM). 6-Aminonicotinamid stÖrt die Glykolyse, was zu einer ATP-Verarmung fÜhrt, und synergisiert mit DNA-vernetzenden Chemotherapeutika wie Cisplatin bei der AbtÖtung von Krebszellen.
- GC46722 6-Chloro-3-indolyl-β-D-Glucuronide (cyclohexylammonium salt) A β-glucuronidase chromogenic substrate
- GC18632 6-hydroxy Bexarotene 6-hydroxy Bexarotene is an oxidative metabolite of bexarotene , a high-affinity ligand for retinoid X receptors (RXRs).
-
GC42580
6-hydroxy Chlorzoxazone
6-hydroxy Chlorzoxazone is a metabolite of chlorzoxazone.
- GC49183 6-hydroxy Etodolac A metabolite of etodolac
- GC18219 6-hydroxy Warfarin 6-hydroxy Warfarin is a metabolite of (+)-warfarin , which is a weaker vitamin K antagonist than (-)-warfarin .
- GC49429 6-keto Lithocholic Acid A metabolite of lithocholic acid
- GC49235 6-Methylmercaptopurine A metabolite of 6-mercaptopurine
- GC49488 6-Methylmercaptopurine-d3 An internal standard for the quantification of 6-MMP
- GC18870 6-NBDG 6-NBDG ist ein fluoreszierendes Glucose-Analogon, es kann zur Fluoreszenzbildgebung und Überwachung des Glucosetransports und -aufnahme verwendet werden.
- GC48721 6-O-Demethyl Griseofulvin A metabolite of griseofulvin
- GC42584 6-O-desmethyl Donepezil 6-O-desmethyl Donepezil is an active metabolite of the acetylcholinesterase inhibitor donepezil.
- GC46726 6-O-Sulfo-β-cyclodextrin (sodium salt) A sulfated cyclodextrin
- GC18335 6β-hydroxy Dexamethasone 6β-hydroxy Dexamethasone is a metabolite of dexamethasone that is more hydrophilic than the parent compound.
- GC49206 7α-hydroxy Dehydroepiandrosterone An active metabolite of dehydroepiandrosterone
- GC49298 7α-Thiomethylspironolactone A major metabolite of spironolactone
- GC49391 7α-Thiospironolactone An active metabolite of spironolactone
- GC40201 7β-hydroxy Cholesterol-d7 7β-hydroxy Cholesterol-d7 is intended for use as an internal standard for the quantification of 7β-hydroxy cholesterol by GC- or LC-MS.
- GC42595 7(Z),11(Z)-Heptacosadiene The mating and social behaviors of insects are largely orchestrated by a suite of volatile cuticular hydrocarbon pheromones.
- GC42596 7(Z),11(Z)-Nonacosadiene 7(Z),11(Z)-Nonacosadien ist das Pheromon von Drosophila melanogaster aus einem Tetrahydrophyridin-Derivat.
- GC42597 7(Z),11(Z)-Pentacosadiene Unsaturated, long-chain hydrocarbons are found on the cuticles of insects and can act as pheromones.
- GC42598 7(Z)-Pentacosene 7(Z)-Pentacosene is an unsaturated cuticular hydrocarbon that acts as a contact sex pheromone in fruit flies.
- GC42599 7(Z)-Tricosene 7(Z)-Tricosene is an unsaturated cuticular hydrocarbon that acts as a pheromone in some insects, including Drosophila.
- GC46080 7,3',4'-Trihydroxyflavone 7,3',4'-Trihydroxyflavon ist eine Flavonoid-Aglycon-Verbindung, die aus Ackerbohnenschoten isoliert wird.
- GC10533 7,8-dihydro-L-Biopterin 7,8-Dihydro-L-Biopterin ist ein Oxidationsprodukt von Tetrahydrobiopterin.
- GC46735 7-Biopterin A pterin
- GC46736 7-Bromoheptanoic Acid A building block
-
GC46242
7-dehydro Cholesterol-d7
7-dehydro Cholesterol (7-DHC) is an immediate precursor of cholesterol
- GC13784 7-Ethoxyresorufin 7-Ethoxyresorufin (Resorufinethylether) ist ein fluorometrisches Substrat und ein kompetitiver Inhibitor von Cytochrom P450, insbesondere CYP1A1.
- GC48649 7-hydroxy Chlorpromazine (hydrochloride) An active metabolite of chlorpromazine
- GC42606 7-hydroxy Coumarin Glucuronide (sodium salt) 7-hydroxy Coumarin glucuronide is a 7-hydroxy coumarin phase II metabolite that can be used as a standard for the analysis of 7-hydroxy coumarin metabolism.
- GC42607 7-hydroxy Coumarin sulfate (potassium salt) 7-hydroxy Coumarin sulfate is a phase II metabolite of coumarin that can be used as an internal standard for the analysis of 7-hydroxy coumarin metabolism using GC- or LC-MS.
- GC49051 7-hydroxy Methotrexate 7-Hydroxy-Methotrexat ist ein Hauptmetabolit von Methotrexat
-
GC42608
7-hydroxy Methotrexate (sodium salt)
7-hydroxy Methotrexate (7-hydroxy MTX) is a phase I metabolite of MTX, which is converted by hepatic aldehyde oxidases.
- GC10565 7-hydroxycoumarinyl Arachidonate 7-Hydroxycumarinylarachidonat (7-HCA) ist ein fluorogenes Substrat der zytosolischen Phospholipase A2 (PLA2).
- GC42611 7-hydroxycoumarinyl-γ-Linolenate 7-Hydroxycumarinyl-γ-Linolenat ist ein fluorogenes Substrat der zytosolischen Phospholipase A2 (cPLA2).
- GC65409 7-Methylcoumarin 7-Methylcumarin, ein Cumarin, weist eine starke hepatoprotektive AktivitÄt und eine starke antioxidative Wirkung auf.
- GC18284 7-Methyluric Acid 7-Methyluric acid is a methylated purine and uric acid derivative.
- GC42620 8-Aminopyrene-1,3,6-trisulfonic Acid (sodium salt) 8-Aminopyrene-1,3,6-trisulfonic Acid (Natriumsalz) ist ein wasserlÖslicher anionischer Fluoreszenzfarbstoff.
- GC52126 8-chloro Caffeine
- GC35201 8-Geranyloxypsoralen 8-Geranyloxypsoralen ist ein aus Grapefruit isoliertes Furanocumarin, das als potenter Inhibitor von P450 3A4 (CYP3A4) mit einem IC50 von 3,93 μM wirkt.
- GC49017 8-hydroxy Amoxapine A metabolite of amoxapine
- GC42626 8-hydroxy Efavirenz 8-hydroxy Efavirenz is a major oxidative metabolite of the non-nucleoside reverse transcriptase inhibitor efavirenz.
- GC18654 8-hydroxy Loxapine 8-hydroxy Loxapine (8-OH loxapine) is a metabolite formed when loxapine , an atypical antipsychotic, is metabolized by the cytochrome P450 isoform CYP1A2.
- GC49544 8-hydroxy Mirtazapine A metabolite of mirtazapine
- GN10330 8-Methoxypsoralen
- GC42633 9(E)-Erythromycin A oxime (9E)-Erythromycin A oxime is a metabolite of the semisynthetic antibiotic roxithromycin .
- GC46757 9(Z),11(E)-Conjugated Linoleic Acid (sodium salt) An isomer of linoleic acid
- GC45366 9(Z)-Pentacosene
- GC42641 9(Z)-Tricosene (9Z)-Tricosene is a pheromone released by insects, including D.
- GC40338 9-deoxy-9-methylene Prostaglandin E2 9-deoxy-9-methylene Prostaglandin E2 (9-deoxy-9-methylene PGE2) is a stable, isosteric analog of PGE2.
- GC40470 9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (Meteneprost) is a potent analog of prostaglandin E2 with an extended half-life in vivo.
- GC42649 9-Nitrooleate Nitrated unsaturated fatty acids, such as 10- and 12-nitrolinoleate, cholesteryl nitrolinoleate, and nitrohydroxylinoleate, represent a new class of endogenous lipid-derived signalling molecules.
- GC42651 9-oxo-10(E),12(E)-Octadecadienoic Acid 9-oxo-10(E),12(E)-Octadecadienoic acid (9-oxoODA) is a natural agonist, abundant in tomatoes, that activates PPARα at 10-20 μM.
- GC46761 9-Oxononanoic Acid An oxidized fatty acid
- GC50419 A 33 A 33 ist ein oral wirksamer und selektiver PDE4B-Hemmer mit einem IC50 von 15 nM.
- GC13262 A-771726 dihydroorotate dehydrogenase inhibitor
- GC46765 A6770 A6770 ist ein oral aktiver, starker Sphingosin-1-Phosphat (S1P)-Lyase (S1PL)-Inhibitor.
- GC15614 A922500 A diacylglycerol acyltransferase 1 inhibitor
- GC15921 A939572 A939572 ist ein potenter und oral bioverfÜgbarer Stearoyl-CoA-Desaturase1 (SCD1)-Inhibitor mit IC50-Werten von <4 nM und 37 nM fÜr mSCD1 bzw. hSCD1.
- GC31355 AA26-9 AA26-9 ist ein potenter Serin-Hydrolase-Hemmer mit breitem Wirkungsspektrum.
-
GC16115
AACOCF3
Inhibitor von cPLA2/Anandamid-Hydrolyse/FAAH
- GC42667 Abacavir Carboxylate Abacavir carboxylate is an inactive metabolite of the HIV-1 reverse transcriptase inhibitor abacavir.
- GC46768 Abaloparatide (acetate) A synthetic derivative of PTHrP and an agonist of PTHR1
- GC17645 Abiraterone A CYP17A1 inhibitor and an active metabolite of abiraterone acetate
- GC11108 Abiraterone acetate A CYP17A1 inhibitor
- GC64010 Abiraterone decanoate Abirateron-Decanoat ist ein wirksames Prodrug von Abirateron. Abirateron-Decanoat sorgt fÜr eine kontrollierte Freisetzung von Abirateron und eine lang wirkende CYP17-Hemmung bei intramuskulÄrer (IM) Verabreichung.