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Home >> Signaling Pathways >> Endocrinology and Hormones

Endocrinology and Hormones

Endocrinology and Hormones

Endocrinology and Hormones

The endocrine system is an information signaling system that coordinates most bodily functions. It senses environmental changes and secretes corresponding hormones to coordinate metabolism, maintain homeostasis, and regulate growth and development.read more

Targets for  Endocrinology and Hormones

Products for  Endocrinology and Hormones

  1. Cat.No. Product Name Information
  2. GC44059 LG 100268 LG 100268 is an agonist of retinoid X receptors (RXRs; Kd = 3 nM). LG 100268 Chemical Structure
  3. GC34173 LG-100064 LG-100064 is a retinoid-X-receptor (RXR) agonist, with EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ; LG-100064 can be used in the research of cancer. LG-100064 Chemical Structure
  4. GC32403 LGD-3303

    LGD-3303 is a selective androgen receptor modulator (SARM).

     LGD-3303 Chemical Structure
  5. GC32408 LGD-4033 An Analytical Reference Standard LGD-4033 Chemical Structure
  6. GC63579 Linuron Linuron is a phenylurea herbicide that is widely used to control the growth of grass and weeds in various agriculture crops and in orchards. Linuron Chemical Structure
  7. GC63884 Linzagolix Linzagolix (KLH-2109; OBE-2109) is a potent, non-peptide, and orally active GnRH antagonist. Linzagolix Chemical Structure
  8. GC36465 Liothyronine An thyroid hormone which binds to TRβ1, and activates its activity Liothyronine Chemical Structure
  9. GC12409 Liothyronine Sodium

    Thyroid hormone (T3) analog

     Liothyronine Sodium Chemical Structure
  10. GC61003 Loperamide D6 hydrochloride Loperamide D6 hydrochloride (R-18553 D6 hydrochloride) is a deuterium labeled Loperamide hydrochloride. Loperamide D6 hydrochloride Chemical Structure
  11. GC36479 Loperamide hydrochloride Loperamide (hydrochloride) (R-18553 (hydrochloride)) is an opioid receptor agonist. Loperamide hydrochloride Chemical Structure
  12. GC52281 Losartan Azide A potential impurity in commercial preparations of losartan Losartan Azide Chemical Structure
  13. GC10257 Losartan Potassium (DuP 753) Losartan Potassium (DuP 753) (DuP-753 potassium) is an angiotensin II receptor type 1 (AT1) antagonist, competing with the binding of angiotensin II to AT1 with an IC50 of 20 nM. Losartan Potassium (DuP 753) Chemical Structure
  14. GC18155 LSZ102

    Estrogen receptor

     LSZ102 Chemical Structure
  15. GC15483 Luffariellolide agonist for the RA receptors RAR α, β, and γ Luffariellolide Chemical Structure
  16. GC49207 Lumisterol 3 A photoisomer of previtamin D3 Lumisterol 3 Chemical Structure
  17. GN10142 Lupeol Lupeol Chemical Structure
  18. GP10088 Luteinizing hormone releasing hormone human acetate salt (LHRH) Luteinizing hormone releasing hormone human acetate salt (LHRH) Chemical Structure
  19. GC36499 LXRβ agonist-2 LXRβ agonist-2 is a highly potent and β-selective liver X receptor (LXRβ) agonist with EC50 of 7 nM, displays 28.5-fold selectivity over LXRα (EC50=200 nM) and used in the treatment of atherosclerosis. LXRβ agonist-2 Chemical Structure
  20. GC13954 LXR-623 Liver X-receptor agonist LXR-623 Chemical Structure
  21. GC36508 LY-2940094 LY-2940094 (BTRX-246040) is a potent, selective and orally available nociceptin receptor (NOP receptor) antagonist with high affinity (Ki=0.105 nM) and antagonist potency (Kb=0.166 nM). LY-2940094 Chemical Structure
  22. GC39193 LY2444296 LY2444296 is an orally bioavailable, high-affinity and selective short-acting kappa opioid receptor (KOPR) antagonist, with a Ki value of ?1 nM. LY2444296 Chemical Structure
  23. GC31380 LY2452473

    LY2452473 is an orally bioavailable, selective androgen receptor modulator (SARM).

     LY2452473 Chemical Structure
  24. GC19421 LY2562175

    LY2562175 is a potent and selective?FXR?agonist with an?EC50?of 193 nM

     LY2562175 Chemical Structure
  25. GC19500 LY2795050

    LY2795050 is a novel selective κ-opioid Receptor (KOR) antagonist

     LY2795050 Chemical Structure
  26. GC19232 LY2955303 LY2955303 is a potent and selective retinoic acid receptor gamma (RARγ) antagonist with a Ki of 1.09 nM. LY2955303 Chemical Structure
  27. GN10301 Magnolol Magnolol Chemical Structure
  28. GC44114 Makisterone A Makisterone A is an ecdysteroid that drives molting in insects. Makisterone A Chemical Structure
  29. GC17874 Matrine An alkaloid with diverse biological activities Matrine Chemical Structure
  30. GC36562 MCOPPB triHydrochloride MCOPPB 3Hcl is a nociceptin receptor agonist with pKi of 10.07; weaker activity at other opioid receptors. MCOPPB triHydrochloride Chemical Structure
  31. GC12385 MDV3100 (Enzalutamide)

    A non-steroidal androgen receptor antagonist

     MDV3100 (Enzalutamide) Chemical Structure
  32. GC11781 Medroxyprogesterone potent progesterone receptor agonist Medroxyprogesterone Chemical Structure
  33. GC12974 Medroxyprogesterone acetate

    Steroidal progestin

     Medroxyprogesterone acetate Chemical Structure
  34. GC61850 Medroxyprogesterone acetate D3 Medroxyprogesterone acetate D3 Chemical Structure
  35. GC11688 Megestrol Acetate Anti-estrogen agent Megestrol Acetate Chemical Structure
  36. GP10066 Melanocyte stimulating hormone release inhibiting factor Melanocyte stimulating hormone release inhibiting factor Chemical Structure
  37. GC25627 Menotropin Menotropin (Human Menopausal Gonadotrophin) is a hormonally active medication for the treatment of fertility disturbances, which are extracted from the urine of postmenopausal women. Menotropin Chemical Structure
  38. GC11016 Meptazinol HCl Partial agonist at the μ1 opioid receptor Meptazinol HCl Chemical Structure
  39. GC44168 Metanephrine

    Metanephrine is a metabolite of epinephrine produced by the action of catechol-O-methyl transferase on epinephrine.

     Metanephrine Chemical Structure
  40. GC49423 Metanephrine-d3 (hydrochloride) An internal standard for the quantification of metanephrine Metanephrine-d3 (hydrochloride) Chemical Structure
  41. GC52325 MeTC7 A vitamin D receptor antagonist MeTC7 Chemical Structure
  42. GC63066 Methenolone acetate Methenolone acetate Chemical Structure
  43. GC47646 Methiocarb A carbamate pesticide Methiocarb Chemical Structure
  44. GC63072 Methyl-6-alpha-Naltrexol Methyl-6-alpha-Naltrexol Chemical Structure
  45. GC16177 Methylnaltrexone Bromide Antagonist of peripherally acting μ-opioid Methylnaltrexone Bromide Chemical Structure
  46. GC17161 Methylpiperidino pyrazole

    ERα selective antagonist

     Methylpiperidino pyrazole Chemical Structure
  47. GC18243 MGL-3196 MGL-3196 (MGL-3196) is a highly selective thyroid hormone receptor β (THR-β) agonist with an EC50 value of 0.21 μM. MGL-3196 Chemical Structure
  48. GC11837 MI-136 menin-MLL interaction inhibitor MI-136 Chemical Structure
  49. GC50279 MK 386 Potent, selective human type 1 5α-reductase inhibitor MK 386 Chemical Structure
  50. GC36621 MK-0773 MK-0773 is a selective androgen receptor modulators (SARMs) that binds to AR with an IC50 of 6.6 nM. MK-0773 Chemical Structure
  51. GC14525 ML 190 κ opioid receptor (KOP) antagonist ML 190 Chemical Structure
  52. GC44216 ML-180 ML-180 is an inverse agonist of liver receptor homolog-1 (LRH-1, IC50 = 3.7 μM) with maximum efficacy of 64% repression. ML-180 Chemical Structure
  53. GC10212 MM 11253

    RARγ antagonist

     MM 11253 Chemical Structure
  54. GC47698 Mometasone A synthetic glucocorticoid with anti-inflammatory and anti-allergic activities Mometasone Chemical Structure
  55. GC18349 Motilin (porcine) Motilin is a polypeptide hormone that stimulates gastric motility through release in the small intestine and into the general circulation during fasting. Motilin (porcine) Chemical Structure
  56. GC11881 MPP dihydrochloride

    ERα receptors silent antagonist

     MPP dihydrochloride Chemical Structure
  57. GC49802 N-Acetyl-L-thyroxine A thyroid hormone derivative N-Acetyl-L-thyroxine Chemical Structure
  58. GC12663 N-Benzylnaltrindole hydrochloride δ2 opioid receptor antagonist N-Benzylnaltrindole hydrochloride Chemical Structure
  59. GC49399 N-Desbutyl Dronedarone (hydrochloride) Debutyldronedarone (SR35021) hydrochloride, the main metabolite of Dronedarone, is a selective thyroid hormone receptor α1 (TRα1) inhibitor. N-Desbutyl Dronedarone (hydrochloride) Chemical Structure
  60. GC32907 N-desmethyl Enzalutamide (N-desmethyl MDV 3100) N-desmethyl Enzalutamide (N-desmethyl MDV 3100) is the active metabolite of Enzalutamide.N-desmethyl Enzalutamide (N-desmethyl MDV 3100) is the active metabolite of Enzalutamide. N-desmethyl Enzalutamide (N-desmethyl MDV 3100) demonstrates primary and secondary pharmacodynamics of similar potency to Enzalutamide and circulates at approximately the same plasma concentrations as enzalutamide. N-desmethyl Enzalutamide (N-desmethyl MDV 3100) Chemical Structure
  61. GC16553 N-Desmethylclozapine 5-HT2C serotonin receptor antagonist N-Desmethylclozapine Chemical Structure
  62. GC14979 N-MPPP Hydrochloride High affinity κ agonist N-MPPP Hydrochloride Chemical Structure
  63. GC36778 N-terminally acetylated Leu-enkephalin N-terminally acetylated Leu-enkephalin is the N-terminally acetylated form of Leu-enkephalin. N-terminally acetylated Leu-enkephalin Chemical Structure
  64. GC44310 Nafarelin (acetate) Nafarelin is an agonist of gonadotropin-releasing hormone (GNRH). Nafarelin (acetate) Chemical Structure
  65. GC45997 Naftifine-d3 (hydrochloride) An internal standard for the quantification of naftifine Naftifine-d3 (hydrochloride) Chemical Structure
  66. GC31314 Nagilactone B

    Nagilactone B is a liver X receptor (LXR) agonist.

     Nagilactone B Chemical Structure
  67. GC46182 Naldemedine A peripherally acting opioid receptor antagonist Naldemedine Chemical Structure
  68. GC44312 Nalfurafine

    Nalfurafine is a κ-opioid receptor (KOR) agonist (EC50 = 0.05 nM for human receptors expressed in CHO cell membranes).

     Nalfurafine Chemical Structure
  69. GC30932 Naloxegol (NKTR-118) Naloxegol (NKTR-118) Chemical Structure
  70. GC30881 Naloxegol oxalate (NKTR-118 oxalate)

    A peripherally acting antagonist of the µ-opioid receptor

     Naloxegol oxalate (NKTR-118 oxalate) Chemical Structure
  71. GC16588 Naloxonazine dihydrochloride Naloxonazine dihydrochloride is a specific μ-opioid receptor antagonist with an IC50 of 5.4 nM. Naloxonazine dihydrochloride Chemical Structure
  72. GC11807 Naloxone (hydrochloride) An opioid inverse agonist drug Naloxone (hydrochloride) Chemical Structure
  73. GC63686 Naloxone methiodide Naloxone methiodide Chemical Structure
  74. GC16206 Naltrexone Opioid receptor antagonist Naltrexone Chemical Structure
  75. GC13688 Naltrindole hydrochloride

    δ opioid antagonist

     Naltrindole hydrochloride Chemical Structure
  76. GC64586 Nandrolone laurate Nandrolone laurate Chemical Structure
  77. GC63096 Nandrolone phenylpropionate Nandrolone phenylpropionate Chemical Structure
  78. GC47747 Napyradiomycin A1 A fungal metabolite with diverse biological activities Napyradiomycin A1 Chemical Structure
  79. GC69541 NDB

    NDB is a selective antagonist of human FXRα (hFXRα) that can effectively regulate the transcription of downstream genes of FXRα. NDB can be used in anti-diabetes research.

     NDB Chemical Structure
  80. GC44363 Neoaureothin Neoaureothin is a bacterial metabolite that has been found in Streptomyces. Neoaureothin Chemical Structure
  81. GC17200 Nestoron A synthetic progestin Nestoron Chemical Structure
  82. GC44375 Neuromedin C (trifluoroacetate salt) Neuromedin C is a bombesin-like neuropeptide that stimulates uterine smooth muscle contraction and the release of gastrin, somatostatin, and amylase in rats. Neuromedin C (trifluoroacetate salt) Chemical Structure
  83. GC44376 Neuromedin N (trifluoroacetate salt) Neuromedin N is a neurotensin-like hexapeptide that is synthesized from the same precursor as neurotensin. Neuromedin N (trifluoroacetate salt) Chemical Structure
  84. GC15408 Neuropeptide AF (human) Endogenous antiopioid peptide implicated in pain modulation and endocrine functions Neuropeptide AF (human) Chemical Structure
  85. GC47769 Neuropeptide S (human) (acetate) A neuropeptide NSPR agonist Neuropeptide S (human) (acetate) Chemical Structure
  86. GC18277 Neuropeptide S (rat) Neuropeptide S is a neuropeptide that is an agonist of the neuropeptide S receptor (NPSR) with an EC50 value of 3.2 nM for the rat peptide to induce intracellular calcium mobilization in HEK293 cells expressing the human receptor. Neuropeptide S (rat) Chemical Structure
  87. GC63595 NH-3 NH-3 is an orally active, reversible thyroid hormone receptor (THR) antagonist with an IC50 of 55 nM. NH-3 Chemical Structure
  88. GC34686 Nidufexor

    An FXR partial agonist

     Nidufexor Chemical Structure
  89. GC44405 Nilutamide Nilutamide is a non-steroidal antiandrogen that is an antagonist of the androgen receptor. Nilutamide Chemical Structure
  90. GC45760 Nilutamide-d6 An internal standard for the quantification of nilutamide Nilutamide-d6 Chemical Structure
  91. GC44446 NO-Losartan A Angiotensin II is a hormone that plays an important role in regulating blood pressure. NO-Losartan A Chemical Structure
  92. GC17325 Nociceptin Endogenous ligand for the NOP opioid receptor Nociceptin Chemical Structure
  93. GC63115 Nociceptin (1-13), amide TFA Nociceptin (1-13), amide TFA is a potent ORL1 receptor (opioid receptor-like 1 receptor, OP4) agonist with a pEC50 of 7.9 for mouse vas deferens and a Ki of 0.75 nM for binding to rat forebrain membranes. Nociceptin (1-13), amide TFA Chemical Structure
  94. GC52189 Nomegestrol Nomegestrol is a potent and orally available progestin, acts as a selective full progesterone receptor agonist, with a Kd of 5.44 nM for rat uterine progesterone receptor, and has moderate antiandrogenic activity and strong antiestrogenic activity. Nomegestrol Chemical Structure
  95. GC45529 Nonapeptide-1 (acetate)   Nonapeptide-1 (acetate) Chemical Structure
  96. GC13645 nor-Binaltorphimine dihydrochloride κ-opioid receptor antagonist nor-Binaltorphimine dihydrochloride Chemical Structure
  97. GC48788 Norethindrone-d6 An internal standard for the quantification of norethindrone Norethindrone-d6 Chemical Structure
  98. GC48803 Norethynodrel A synthetic progestin Norethynodrel Chemical Structure
  99. GC47797 Norgestimate-d6 An internal standard for the quantification of norgestimate Norgestimate-d6 Chemical Structure
  100. GC13196 NVP-QAV680 potent and selective CRTh2 receptor antagonist NVP-QAV680 Chemical Structure
  101. GC44479 o,p'-DDE o,p'-DDE is a metabolite and degradation product of the organochlorine pesticide DDT. o,p'-DDE Chemical Structure

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