Cell Cycle/Checkpoint

Cat.No. Product Name Information

GC61584 Vinflunine ditartrate Vinflunine ditartrate is the first fluorinated microtubule inhibitor belonging to the Vinca alkaloids family. Vinflunine ditartrate has anti-angiogenic, vascular-disrupting and anti-metastatic activities. Vinflunine ditartrate can be used for the research of transitional cell carcinoma of the urothelial tract, non-small cell lung cancer, and carcinoma of the breast. Vinflunine ditartrate Chemical Structure

Vinflunine ditartrate Chemical Structure

GC13815 Vinflunine Tartrate

Etanercept is an inhibitor of the inflammatory factor TNF-α and is mainly used for the clinical treatment of rheumatoid arthritis .

GN10299 Vinorelbine Vinorelbine Chemical Structure

GC14806 Vinorelbine ditartrate

KW 2307

An inhibitor of microtubule polymerization Vinorelbine ditartrate Chemical Structure

GC45149 VK3-OCH3

Vitamin K3-OCH3

VK3-OCH3 is an analog of vitamin K3 that that has antiproliferative activities in vitro. VK3-OCH3 Chemical Structure

GC11007 VO-Ohpic trihydrate A specific inhibitor of PTEN VO-Ohpic trihydrate Chemical Structure

GC64562 VPC-70619 VPC-70619 is a potent, orally active N-Myc inhibitor. VPC-70619 blocks the N-Myc-Max heterocomplex from binding to DNA E-boxes and demonstrated strong inhibition activity against N-Myc-dependent cell lines as well as high bioavailability in both oral and intraperitoneal administration. VPC-70619 Chemical Structure

GC45595 Vulpinic Acid

NSC 5897

GC49430 Wee1 Inhibitor Wee1 Inhibitor is a potent checkpoint Wee1 kinase inhibitor with an IC50 of 0.011 μM. Wee1 Inhibitor Chemical Structure

GC62449 WEE1-IN-3 WEE1-IN-3 is a potent Wee1 kinase inhibitor with an IC50 of <10 nM. WEE1-IN-3 has anticancer activities. WEE1-IN-3 Chemical Structure

GC65994 WEE1-IN-5 WEE1-IN-5 is a potent WEE1 inhibitor with an IC50 value of 0.8 nM. WEE1-IN-5 inhibits phospho-CDC2. WEE1-IN-5 abrogates the G2 check point, increasing sensitivity to DNA damaging agents in cancer cells. WEE1-IN-5 can be used for researching anticancer. WEE1-IN-5 Chemical Structure

GC16000 WHI-P180

Janex 3

EGFR/Janus Kinase 3 inhibitor WHI-P180 Chemical Structure

GC48969 Withanone

NSC 179884

A phytochemical with diverse biological activities Withanone Chemical Structure

GC12338 Wortmannin

KY 12420

Wortmannin is a highly potent direct inhibitor of PI3-kinase specificity originally derived from fungi (1,2). Wortmannin Chemical Structure

GC18117 XL413 Cdc7 inhibitor XL413 Chemical Structure

GC13328 XL413 hydrochloride

BMS-863233 hydrochloride

Cdc7 inhibitor

GC15712 Y-27632

A ROCK inhibitor,potent and selective

GC10512 Y-27632 dihydrochloride

y-27632, Y27632, Y-27632 dihydrochloride, Y 27632

A ROCK inhibitor

Y-27632 dihydrochloride Chemical Structure

GC37947 Y-33075

RKI-983, SNJ-1656, Y-39983

Y-33075 is a selective ROCK inhibitor derived from Y-27632, and is more potent than Y-27632, with an IC50 of 3.6 nM. Y-33075 Chemical Structure

GC13423 Y-39983 dihydrochloride ROCK family inhibitor Y-39983 dihydrochloride Chemical Structure

GC18578 YK-3-237 An inhibitor of tubulin polymerization and activator of SIRT1 YK-3-237 Chemical Structure

GC48471 Z-(L-Arg)-AMC (hydrochloride)

Bz-Arg-AMC, N-benzoxy-L-Arg-7-amido-4-methylcoumarin, N-benzoyl-L-Arg-AMC, Z-Arg(HCl)AMC

Z-(L-Arg)-AMC (hydrochloride) is a fluorogenic substrate for trypsin and papain.

Z-(L-Arg)-AMC (hydrochloride) Chemical Structure

GC45177 Z-AEVD-FMK

Z-Ala-Glu-Val-Asp-Fluoromethyl Ketone

Z-AEVD-FMK is an irreversible inhibitor of caspase-10 and related caspases.

GA23742 Z-D-Arg-Gly-Arg-pNA . 2 HCl

Benzyl-D-Arg-Gly-Arg-pNA, Benzyl-D-Arg-Gly-Arg-p-nitroanilide, Factor Xa Chromogenic Substrate, S-2765

Z-RGR-pNA is a chromogenic substrate for the determination of factor Xa. Z-D-Arg-Gly-Arg-pNA . 2 HCl Chemical Structure

GC13859 Z-DEVD-AFC

Caspase-3 Fluorogenic Substrate IV

A caspase-3 fluorogenic substrate Z-DEVD-AFC Chemical Structure

GC49145 Z-FR-AMC (trifluoroacetate salt)

Z-FR-7-amino-4-Methylcoumarin, Z-Phe-Arg-AMC

A fluorogenic substrate for cathepsin L Z-FR-AMC (trifluoroacetate salt) Chemical Structure

GC45181 Z-IETD-AFC

Z-Ile-Glu-Thr-Asp-7-amino-4-Trifluormethylcoumarin

Z-IETD-AFC is a fluorogenic substrate for caspase-8 and granzyme B. Z-IETD-AFC Chemical Structure

GC40151 Z-VAD-AMC (acetate)

Z-Val-Ala-Asp-AMC, Z-Val-Ala-Asp-7-amino-4-methylcoumarin

Z-VAD-AMC is a fluorogenic substrate for caspase-1. Z-VAD-AMC (acetate) Chemical Structure

GC70163 Zagotenemab

LY33003560

Zagotenemab (LY3303560) is a humanized anti-tau antibody that selectively binds and neutralizes tau deposits in the brain. Zagotenemab can be used for research on Alzheimer's disease.