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Accueil >> Signaling Pathways >> Proteases

Proteases

Proteases is a general term for a class of enzymes that hydrolyze protein peptide chains. According to the way they degrade polypeptides, they are divided into two categories: endopeptidases and telopeptidases. The former can cut the large molecular weight polypeptide chain from the middle to form prions and peptones with smaller molecular weights; the latter can be divided into carboxypeptidase and aminopeptidase, which respectively remove the peptide from the free carboxyl terminus or free amino terminus of the polypeptide one by one. Chain hydrolysis produces amino acids.

A general term for a class of enzymes that hydrolyze peptide bonds in proteins. According to the way they hydrolyze polypeptides, they can be divided into endopeptidases and exopeptidases. Endopeptidase cleaves the interior of the protein molecule to form smaller molecular weight peptones and peptones. Exopeptidase hydrolyzes peptide bonds one by one from the end of the free amino group or carboxyl group of protein molecules, and frees amino acids, the former is aminopeptidase and the latter is carboxypeptidase. Proteases can be classified into serine proteases, sulfhydryl proteases, metalloproteases and aspartic proteases according to their active centers and optimum pH. According to the optimum pH value of its reaction, it is divided into acidic protease, neutral protease and alkaline protease. The proteases used in industrial production are mainly endopeptidases.

Proteases are widely found in animal offal, plant stems and leaves, fruits and microorganisms. Microbial proteases are mainly produced by molds and bacteria, followed by yeast and actinomycetes.

Enzymes that catalyze the hydrolysis of proteins. There are many kinds, the important ones are pepsin, trypsin, cathepsin, papain and subtilisin. Proteases have strict selectivity for the reaction substrates they act on. A protease can only act on certain peptide bonds in protein molecules, such as the peptide bonds formed by the hydrolysis of basic amino acids catalyzed by trypsin. Proteases are widely distributed, mainly in the digestive tract of humans and animals, and are abundant in plants and microorganisms. Due to limited animal and plant resources, the industrial production of protease preparations is mainly prepared by fermentation of microorganisms such as Bacillus subtilis and Aspergillus terrestris.

Targets for  Proteases

Products for  Proteases

  1. Cat.No. Nom du produit Informations
  2. GC38556 1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine La 1-myristoyl-2-stéaroyl-sn-glycéro-3-phosphocholine est un métabolite endogène. 1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine Chemical Structure
  3. GC30641 1-Naphthol (Fourrine ERN) Le 1-naphtol est une sonde moléculaire fluorescente À transfert de protons À l'état excité (ESPT). 1-Naphthol (Fourrine ERN) Chemical Structure
  4. GC39470 1-Octanol Le 1-octanol (Octanol), un alcool gras saturé, est un inhibiteur des canaux calciques de type T (canaux T) avec une IC50 de 4 μM pour les courants T natifs. 1-Octanol Chemical Structure
  5. GC74657 1-Octanol-d17

    Octanol-d17

     1-Octanol-d17 est le deutérium marqué 1-Octanol. 1-Octanol-d17 Chemical Structure
  6. GC40183 1-Oleoyl Glycerol

    18:1-MG, MG(18:1), 1-Monoolein, 1-Oleoyl-rac-glycerol

     Le 1-oléoyl glycérol est un métabolite endogène. 1-Oleoyl Glycerol Chemical Structure
  7. GC92061 1-Palmitoyl-2-13(S)-HODE-sn-glycero-3-PC

    1-Hexadecanoyl-2-13(S)-HODE-sn-glycero-3-Phosphocholine; 13(S)-Hydroxyoctadecadienoic Acid-PLPC; 1-Palmitoyl-2-13(S)-HODE-sn-glycero-3-Phosphocholine; 1-Palmitoyl-2-(13-hydroxy-cis-9,trans-11-octadecadienoyl)-L-3-phosphatidylcholine

     1-Palmitoyl-2-13(S)-HODE-sn-glycero-3-PC sont des Phospholipides oxydés contenant de l'acide palmitique et du 13s - hode aux positions Sn - 1 et Sn - 2, respectivement. 1-Palmitoyl-2-13(S)-HODE-sn-glycero-3-PC Chemical Structure
  8. GC46488 1-Palmitoyl-2-Docosahexaenoyl-sn-glycero-3-PC

    1-Palmitoyl-2-Docosahexaenoyl-sn-glycero-3-Phosphocholine, 1-Palmitoyl-2-Docosahexaenoyl-sn-glycero-3-Phosphatidylcholine, PC(16:0/22:6), 16:0/22:6-PC, PDPC

     A phospholipid 1-Palmitoyl-2-Docosahexaenoyl-sn-glycero-3-PC Chemical Structure
  9. GC68501 1-Palmitoyl-2-oleoyl-sn-glycerol

    1-Palmitoyl-2-oleoyl-sn-glycerol est un métabolite endogène et le principal diacylglycérol dans le facteur inducteur d'hypoxie (HIF)-1 des algues.

     1-Palmitoyl-2-oleoyl-sn-glycerol Chemical Structure
  10. GC49366 1-Salicylate Glucuronide

    Salicyl Phenolic Glucuronide, Salicylic Acid Phenolic Glucuronide

     A metabolite of salicylic acid and aspirin 1-Salicylate Glucuronide Chemical Structure
  11. GC42039 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC

    15(S)-HETE-SAPC, 15(S)-Hydroxyeicostetraenoic Acid-SAPC, 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-Phosphatidylcholine

     1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position. 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC Chemical Structure
  12. GC42040 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE

    15(S)-HETE-SAPE, 15(S)-Hydroxyeicosatetraenoic Acid-SAPE, 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-Phosphatidylethanolamine

     1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position. 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE Chemical Structure
  13. GC49730 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE-d11

    15(S)-HETE-SAPE-d11, 15(S)-Hydroxyeicosatetraenoic Acid-SAPE-d11, 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-Phosphatidylethanolamine-d11

     An internal standard for the quantification of 1-stearoyl-2-15(S)-HETE-sn-glycero-3-PE 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE-d11 Chemical Structure
  14. GC42041 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC

    15(S)-HpETE-SAPC, 15(S)-Hydroperoxyeicostetraenoic Acid-SAPC, 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-Phosphatidylcholine

     1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position. 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC Chemical Structure
  15. GC42042 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE

    1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-phosphoethanolamine, 15(S)-HpETE-SAPE, 15(S)-hydroperoxyeicostetraenoic acid-SAPE

     1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position. 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE Chemical Structure
  16. GC11139 1-Stearoyl-2-Arachidonoyl-sn-glycero-3-PC

    SAPC

     A phospholipid 1-Stearoyl-2-Arachidonoyl-sn-glycero-3-PC Chemical Structure
  17. GC68502 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine

    Le stéaroyl-2-linoléoyl-sn-glycéro-3-phosphocholine peut être choisi comme composé volatil modèle pour étudier les différentes espèces de phosphatidylcholine oxydées. Cette méthode est appliquée aux échantillons alimentaires réels, tels que la lécithine de soja.

     1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine Chemical Structure
  18. GC40971 10(S),17(S)-DiHDHA

    10(S),17(S)-DiHDoHE, PDX, Protectin DX

     La 10(S),17(S)-DiHDHA (également connue sous le nom de neuroprotectine D1 lorsqu'elle est produite dans les tissus neuronaux) est un acide gras dihydroxy dérivé du DHA qui présente de puissantes activités protectrices et anti-inflammatoires. 10(S),17(S)-DiHDHA Chemical Structure
  19. GC49820 10,11-dihydro-10,11-dihydroxy Carbamazepine

    10,11-dihydro-10,11-dihydroxy CBZ, CBZ-diol, Dihydroxycarbazepine, Dihydroxycarbamazepine

     A metabolite of carbamazepine and oxcarbazepine 10,11-dihydro-10,11-dihydroxy Carbamazepine Chemical Structure
  20. GC66057 10,11-Dihydrocarbamazepine La 10,11-dihydrocarbamazépine est le métabolite actif de l'oxcarbazépine. La 10,11-dihydrocarbamazépine est également un intermédiaire. L'oxcarbazépine est rapidement et presque complètement convertie en 10,11-dihydrocarbamazépine avec une efficacité anticonvulsivante probable. 10,11-Dihydrocarbamazepine Chemical Structure
  21. GC38881 10,12-Tricosadiynoic acid L'acide 10,12-tricosadiynoÏque est un inhibiteur de l'acyl-CoA oxydase-1 (ACOX1) hautement spécifique, sélectif, de haute affinité et actif par voie orale. 10,12-Tricosadiynoic acid Chemical Structure
  22. GC49872 10-Formyltetrahydrofolate (sodium salt) (technical grade)

    10-CHO-FH4, 10-CHO-THF, N10-Formyltetrahydrofolate, 10-formyl H4PteGlu, 10-fTHF

     Le 10-formyltétrahydrofolate (sel de sodium) (qualité technique) est une forme d'acide tétrahydrofolique qui agit comme donneur de groupes formyle dans l'anabolisme. 10-Formyltetrahydrofolate (sodium salt) (technical grade) Chemical Structure
  23. GC49118 10-hydroxy Warfarin A metabolite of (R)-warfarin 10-hydroxy Warfarin Chemical Structure
  24. GC33800 10Z-Nonadecenoic acid

    Nonadeca-10(Z)-enoic Acid

     L'acide 10Z-nonadécénoÏque est une sorte d'acide gras À longue chaÎne ayant une activité anti-tumorale. 10Z-Nonadecenoic acid Chemical Structure
  25. GC40368 11(R)-HEPE 11(R)-HEPE is produced by the oxidation of EPA by 11(R)-LO. 11(R)-HEPE Chemical Structure
  26. GC40445 11(R)-HETE

    11(R)-Hydroxyeicosatetraenoic Acid

     11(R)-HETE is biosynthesized by 11(R)-LOs of the sea urchin, S. 11(R)-HETE Chemical Structure
  27. GC39223 11-Beta-hydroxyandrostenedione

    11β-Hydroxy-4-androsten-3,17-dione, NSC 12168, NSC 17102, 11OHA4, U-2826

     La 11-bêta-hydroxyandrostènedione (4-androsten-11β-ol-3,17-dione) est un stéroÏde principalement présent dans l'origine surrénalienne (la 11β-hydroxylase est présente dans le tissu surrénal, mais absente dans le tissu ovarien). 11-Beta-hydroxyandrostenedione Chemical Structure
  28. GC40730 11-cis Vaccenyl Acetate L'acétate de vaccényle 11-cis est un lipide spécifique aux mâles qui médie le comportement d'agrégation chez les mouches mâles et femelles, ce qui active quelques dizaines de neurones olfactifs situés dans la sensille T1 sur l'antenne des mouches mâles et femelles. 11-cis Vaccenyl Acetate Chemical Structure
  29. GC40394 11-deoxy Corticosterone

    DOC, NSC 11319, 21-hydroxy Progesterone

    11-désoxy Corticostérone est une hormone stéroïde produite par la glande surrénale qui possède une activité minéralocorticoïde et agit comme précurseur de l'aldostérone.

     11-deoxy Corticosterone Chemical Structure
  30. GC10821 11-keto-β-Boswellic Acid

    11-oxo-β-Boswellic acid,KBA

     L'acide 11-céto-bêta-boswellique (11-céto-β -acide boswellique) est un acide triterpénique pentacyclique de la résine d'oléogume de l'écorce de l'arbre dentelé Boswellia, populairement connu sous le nom d'encens indien. L'acide 11-céto-bêta-boswellique a une activité anti-inflammatoire principalement due À l'inhibition de la 5-lipoxygénase (5-LOX) et de l'activation ultérieure des leucotriènes et du facteur nucléaire kappa B (NF-κ B) et de la génération alpha du facteur de nécrose tumorale production. 11-keto-β-Boswellic Acid Chemical Structure
  31. GC61538 11-Oxo etiocholanolone

    5β-Androstane-3α-ol-11,17-dione, 11-keto Etiocholanolone, NSC 53896

     11-Oxo étiocholanolone (11-Ketoetiocholanolone) est un métabolite de l'étiocholanolone. 11-Oxo etiocholanolone Chemical Structure
  32. GC41144 11-trans Leukotriene C4

    11trans LTC4

     11-trans Leukotriene C4 (11-trans LTC4) is a C-11 double bond isomer of LTC4. 11-trans Leukotriene C4 Chemical Structure
  33. GC41147 11-trans Leukotriene D4

    11trans LTD4

     11-trans Leukotriene D4 (11-trans LTD4) is a C-11 double bond isomer of LTD4. 11-trans Leukotriene D4 Chemical Structure
  34. GC41149 11-trans Leukotriene E4

    11trans LTE4

     Le 11-trans leucotriène E4 est un isomère du leucotriène E4 (LTE4). 11-trans Leukotriene E4 Chemical Structure
  35. GC63796 116-9e

    MAL2-11B

     116-9e (MAL2-11B) est un inhibiteur de l'ADNJA1 co-chaperon Hsp70. 116-9e Chemical Structure
  36. GC34016 11beta-Hydroxyprogesterone (11β-Hydroxyprogesterone)

    21-Deoxycorticosterone, 11β-OHP, 11β-hydroxy Progesterone, NSC 15469, U-1701

     La 11bêta-hydroxyprogestérone (11&bêta ;-hydroxyprogestérone) est un puissant inhibiteur de la 11β ;-hydroxystéroÏde déshydrogénase ; active également le récepteur minéralocorticoÏde humain dans les cellules COS-7 avec une DE50 de 10 nM. 11beta-Hydroxyprogesterone (11β-Hydroxyprogesterone) Chemical Structure
  37. GC40447 12(R)-HETE

    12(R)-Hydroxyeicosatetraenoic Acid

     Biosynthesis of 12(R)-HETE in invertebrates is via lipoxygenation of arachidonic acid. 12(R)-HETE Chemical Structure
  38. GC40371 12(S)-HEPE 12(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 12-LO. 12(S)-HEPE Chemical Structure
  39. GC40448 12(S)-HETE

    12(S)-Hydroxyeicosatetraenoic Acid

    12(S)-HETE is the predominant lipoxygenase product of mammalian platelets.

     12(S)-HETE Chemical Structure
  40. GC40449 12(S)-HETE MaxSpec® Standard 12(S)-HETE is the predominant lipoxygenase product of mammalian platelets. 12(S)-HETE MaxSpec® Standard Chemical Structure
  41. GC40349 12(S)-HETE-19,20-alkyne

    Click Tag 12(S)-HETE-19,20-alkyne, Click Tag 12(S)-Hydroxyeicosatetraenoic Acid-19,20-alkyne

     12(S)-HETE is the predominant lipoxygenase product of mammalian platelets. 12(S)-HETE-19,20-alkyne Chemical Structure
  42. GC41882 12(S)-HETrE 12(S)-HETrE is produced by 12-lipoxygenase oxidation of dihomo-γ-linolenic acid (DGLA). 12(S)-HETrE Chemical Structure
  43. GC41095 12(S)-HpEPE

    12(S)-HpEPE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 12-lipoxygenase on eicosapentaenoic acid.

     12(S)-HpEPE Chemical Structure
  44. GC41122 12(S)-HpETE 12(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of platelet or leukocyte 12-lipoxygenase (12-LO) on arachidonic acid. 12(S)-HpETE Chemical Structure
  45. GC41123 12-epi Leukotriene B4

    12epi LTB4

     Leukotriene B4 (LTB4) compounds are produced by both enzymatic and non-enzymatic processes. 12-epi Leukotriene B4 Chemical Structure
  46. GC46416 12-epi Leukotriene B4-d4

    12epi LTB4d4

     A neuropeptide with diverse biological activities 12-epi Leukotriene B4-d4 Chemical Structure
  47. GC45962 12-hydroxy Lauric Acid

    ω-hydroxy Lauric Acid, NSC 159293, NSC 664211

     L'acide 12-hydroxylaurique est un métabolite endogène. 12-hydroxy Lauric Acid Chemical Structure
  48. GC60443 12-Ketodeoxycholic acid

    12-keto LCA, 12-keto Lithocholate, 12-KLCA, 12-oxo LCA, 12-oxo Lithocholate, 12-oxo Lithocholic Acid

     L'acide 12-cétodésoxycholique est un acide biliaire, métabolite du rein. 12-Ketodeoxycholic acid Chemical Structure
  49. GC41096 12-oxo Leukotriene B4

    12keto LTB4, 12oxo LTB4

     Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-LO pathway. 12-oxo Leukotriene B4 Chemical Structure
  50. GC46418 12-oxo-13-HOME An oxylipin 12-oxo-13-HOME Chemical Structure
  51. GC90652 12-oxo-9(Z)-Dodecenoic Acid

    Un métabolite de l'acide linoléique et de l'acide linolénique.

     12-oxo-9(Z)-Dodecenoic Acid Chemical Structure
  52. GC40372 12-OxoETE

    12KETE

     12-OxoETE is synthesized by human platelets and Aplysia nervous tissue after incubation with arachidonic acid. 12-OxoETE Chemical Structure
  53. GC19462 13(R)-HODE 13(R)-HODE is the opposite enantiomer of the 13(S)-HODE produced when linoleic acid is incubated with soybean lipoxygenase. 13(R)-HODE Chemical Structure
  54. GC19463 13(S)-HODE

    13(S)-HODE

     13(S)-HODE (13(S)-HODE), le produit du métabolisme de la 15-lipoxygénase (15-LOX) de l'acide linoléique, fonctionne comme le ligand endogène pour activer PPARγ. 13(S)-HODE Chemical Structure
  55. GC41220 13(S)-HODE methyl ester 13(S)-hydroxyoctadecadienoic acid (13(S)-HODE) is a 15-lipoxygenase metabolite of linoleic acid produced in endothelial cells, leukocytes, and tumor cells. 13(S)-HODE methyl ester Chemical Structure
  56. GC41896 13(S)-HODE-biotin 13(S)-HODE is the lipoxygenase metabolite of linoleic acid. 13(S)-HODE-biotin Chemical Structure
  57. GC46420 13(S)-HODE-d4 An internal standard for the quantification of 13-HODE 13(S)-HODE-d4 Chemical Structure
  58. GC41897 13(S)-HOTrE 13(S)-HOTrE is the 15-lipoxygenase (15-LO) product of linolenic acid. 13(S)-HOTrE Chemical Structure
  59. GC41898 13(S)-HOTrE(γ) 13(S)-HOTrE(γ) is the 15-LO product of γ-linolenic acid. 13(S)-HOTrE(γ) Chemical Structure
  60. GC19474 13(S)-HpODE 13(S)-HpODE is produced by the oxidation of linoleic acid by lipoxygenase-1 (LO-1) in many plants including soybean, flaxseed, apples, and tea leaves,1,2 and by 15-LO in mammals. 13(S)-HpODE Chemical Structure
  61. GC41899 13(S)-HpOTrE

    13(S)-HpOTrE is a monohydroperoxy polyunsaturated fatty acid produced in soybeans by the action of soybean LO-2 on esterified α-linolenic acid.

     13(S)-HpOTrE Chemical Structure
  62. GC41900 13(S)-HpOTrE(γ) 13(S)-HpOTrE(γ) is a monohydroxy PUFA produced by the action of soybean lipoxygenase-1 (LO-1) on γ-linolenic acid. 13(S)-HpOTrE(γ) Chemical Structure
  63. GC62758 13-cis-Vitamin A palmitate Le palmitate de 13-cis-vitamine A (palmitate de 13-cis-rétinyle) est un isomère 13-cis formé par le palmitate de vitamine A dans les flocons de maÏs. 13-cis-Vitamin A palmitate Chemical Structure
  64. GC41911 13-epi-12-oxo Phytodienoic Acid

    13epi12oxo PDA

     13-epi-12-oxo Phytodienoic acid (13-epi-12-oxo PDA) is a lipoxygenase metabolite of α-linolenic acid in the leaves of green plants such as corn. 13-epi-12-oxo Phytodienoic Acid Chemical Structure
  65. GC46436 13-OxoODE-d3

    13KODEd3

     A neuropeptide with diverse biological activities 13-OxoODE-d3 Chemical Structure
  66. GC49759 13C17-Mycophenolic Acid

    13C17-MPA

     An internal standard for the quantification of mycophenolic acid 13C17-Mycophenolic Acid Chemical Structure
  67. GC41206 14(S)-HDHA

    14(S)-hydroxy Docosahexaenoic Acid, 14(S)-HDoHE

     La 14(S)-HDHA (14(S)-HDoHE) est un produit d'oxygénation de l'acide docosahexaénoÏque (DHA). 14(S)-HDHA Chemical Structure
  68. GC41100 14,15-dehydro Leukotriene B4

    14,15dehydro LTB4

     Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-lipoxygenase pathway. 14,15-dehydro Leukotriene B4 Chemical Structure
  69. GC41145 14,15-Leukotriene C4

    Eoxin C4, EXC4, 14,15LTC4

     Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes. 14,15-Leukotriene C4 Chemical Structure
  70. GC41148 14,15-Leukotriene D4

    Eoxin D4, EXD4, 14,15-LTD4

     14,15-Leukotriene D4 (14,15-LTD4) is a member of an alternate class of LTs synthesized by a pathway involving the dual actions of 15- and 12-lipoxygenases (15- and 12-LOs) on arachidonic acid via 15-HpETE and 14,15-LTA4 intermediates. 14,15-Leukotriene D4 Chemical Structure
  71. GC41150 14,15-Leukotriene E4

    Eoxin E4, EXE4, 14,15LTE4

     Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes. 14,15-Leukotriene E4 Chemical Structure
  72. GC41415 15(R)-Lipoxin A4

    AT-Lipoxin A4

    Lipid-derived lipoxins are produced at the site of vascular and mucosal inflammation where they down-regulate polymorphonuclear leukocyte recruitment and function.

     15(R)-Lipoxin A4 Chemical Structure
  73. GC40427 15(S)-HEDE 15(S)-HEDE is produced from 11Z,14Z-eicosadienoic acid by 15-LO. 15(S)-HEDE Chemical Structure
  74. GC40373 15(S)-HEPE

    15S-hydroxy-Eicosapentaenoic Acid

     15(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 15-LO. 15(S)-HEPE Chemical Structure
  75. GC40374 15(S)-HEPE MaxSpec® Standard 15(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 15-LO. 15(S)-HEPE MaxSpec® Standard Chemical Structure
  76. GC46441 15(S)-HEPE-d5

    15S-Hydroxyeicosapentaenoic Acid-d5

     A neuropeptide with diverse biological activities 15(S)-HEPE-d5 Chemical Structure
  77. GC40451 15(S)-HETE

    15(S)-Hydroxyeicosatetraenoic Acid

     15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. 15(S)-HETE Chemical Structure
  78. GC41925 15(S)-HETE Ethanolamide

    15(S)-HAEA, 15(S)-Hydroxyeicosatetraenoic Acid Ethanolamide

     Arachidonoyl ethanolamide was the first endogenous cannabinoid (CB) to be isolated and characterized as an agonist acting on the same receptors (CB1 and CB2) as THC. 15(S)-HETE Ethanolamide Chemical Structure
  79. GC40452 15(S)-HETE MaxSpec® Standard 15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. 15(S)-HETE MaxSpec® Standard Chemical Structure
  80. GC40839 15(S)-HETE methyl ester

    15(S)-Hydroxyeicosatetraenoic Acid methyl ester

     15(S)-HETE methyl ester is a synthetic derivative of 15(S)-HETE, a major arachidonic acid metabolite from the 15-lipoxygenase pathway. 15(S)-HETE methyl ester Chemical Structure
  81. GC41926 15(S)-HETE-biotin

    15(S)-Hydroxyeicosatetraenoic Acid-biotin

     15(S)-HETE is a major arachidonic acid metabolite produced by the 15-lipoxygenase pathway. 15(S)-HETE-biotin Chemical Structure
  82. GC46442 15(S)-HETE-d8

    15(S)-Hydroxyeicosatetraenoic Acid-d8

     An internal standard for the quantification of 15-HETE 15(S)-HETE-d8 Chemical Structure
  83. GC49894 15(S)-HETE-d8 ethyl ester

    15(S)-Hydroxyeicosatetraenoic Acid-d8 ethyl ester

     An internal standard for the quantification of 15(S)-HETE ethyl ester 15(S)-HETE-d8 ethyl ester Chemical Structure
  84. GC41927 15(S)-HETrE 15(S)-HETrE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of dihomo-γ-linolenic acid. 15(S)-HETrE Chemical Structure
  85. GC41403 15(S)-HpEDE

    15(S)-HpEDE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 15-lipoxygenase on eicosadienoic acid.

     15(S)-HpEDE Chemical Structure
  86. GC41101 15(S)-HpEPE

    15(S)-HpEPE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 15-lipoxygenase on eicosapentaenoic acid.

     15(S)-HpEPE Chemical Structure
  87. GC41124 15(S)-HpETE

    15(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonic acid.

     15(S)-HpETE Chemical Structure
  88. GC11988 15-acetoxy Scirpenol

    4-Deacetylanguidin,NSC 267030

     Le 15-acétoxyscirpénol, l'une des mycotoxines du groupement acétoxyscirpénol (ASM), induit fortement l'apoptose et inhibe la croissance des lymphocytes T Jurkat de manière dose-dépendante en activant d'autres caspases indépendantes de la caspase-3. 15-acetoxy Scirpenol Chemical Structure
  89. GC19442 15-Acetyldeoxy Nivalenol

    15-Acetyl Vomitoxin, 15-AcDON, Deoxynivalenol 15-acetate, DON 15-acetate

     Le 15-acétyldésoxy nivalénol est un trichothécène hautement toxique présent dans les céréales, et un métabolite du désoxynivalénol, présente une toxicité pour les cellules HepG2. 15-Acetyldeoxy Nivalenol Chemical Structure
  90. GC41937 15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide

    15ketoBimatoprost, 17phenyl trinor PGF2α ethyl amide

     Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide), an F-series PG analog which has been approved for use as an ocular hypotensive drug. 15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide Chemical Structure
  91. GC41938 15-Lipoxygenase Inhibitor 1

    15LO Inhibitor 1

     L'inhibiteur de 15-lipoxygénase 1 est un inhibiteur sélectif de la 15-lipoxygénase, avec une CI50 de 18 μM. L'inhibiteur de la 15-lipoxygénase 1 a des CI50 de 19,5 μM et 19,1 μM pour la 15-lipoxygénase de soja (SLO) et la 15-lipoxygénase-1 humaine (15-LOX-1), respectivement. L'inhibiteur de la 15-lipoxygénase 1 a un potentiel pour la recherche sur le cancer de la prostate. 15-Lipoxygenase Inhibitor 1 Chemical Structure
  92. GC41940 15-OxoEDE

    15KEDE

     15-OxoEDE is produced by the oxidation of 15-HEDE. 15-OxoEDE Chemical Structure
  93. GC40376 15-OxoETE

    15KETE

     15-OxoETE is produced by oxidation of the 15-hydroxyl of 15-HETE. 15-OxoETE Chemical Structure
  94. GC41309 16α-hydroxy Prednisolone 16α-hydroxy Prednisolone est un métabolite stéréosélectif de l'épimère 22(R) du budésonide glucocorticoÏde via les enzymes du cytochrome P450 3A (CYP3A). 16α-hydroxy Prednisolone Chemical Structure
  95. GC35058 16-Dehydroprogesterone La 16-déhydroprogestérone est un progestatif stéroïdien. 16-Dehydroprogesterone Chemical Structure
  96. GC46451 16F16 A PDI inhibitor 16F16 Chemical Structure
  97. GC45909 17α-hydroxy Pregnenolone

    NSC 63853, 17-α-OH Pregnenolone

     1α-hydroxy Pregnenolone est un stéroÏde pregnane. 17α-hydroxy Pregnenolone Chemical Structure
  98. GC71338 17β-HSD10-IN-1 17β-HSD10-IN-1 (composé 9) est un inhibiteur actif par voie orale de la 17β - hydroxystéroïde déshydrogénase de type 10 (17β - hsd10) avec perméabilité hémato - encéphalique. 17β-HSD10-IN-1 Chemical Structure
  99. GC41300 17β-hydroxy Exemestane 17β-hydroxy Exemestane is the primary active metabolite of exemestane. 17β-hydroxy Exemestane Chemical Structure
  100. GC46471 17β-hydroxy Exemestane-d3 A neuropeptide with diverse biological activities 17β-hydroxy Exemestane-d3 Chemical Structure
  101. GC41951 17(R)-Resolvin D1

    Aspirin-triggered Resolvin D1

    Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid and docosahexaenoic acid.

     17(R)-Resolvin D1 Chemical Structure

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