Endocrinology and Hormones
Endocrinology and Hormones
The endocrine system is an information signaling system that coordinates most bodily functions. It senses environmental changes and secretes corresponding hormones to coordinate metabolism, maintain homeostasis, and regulate growth and development.read more
Targets for Endocrinology and Hormones
- 5-alpha Reductase(8)
- Smoothened Receptors(3)
- Androgen Receptor(137)
- Aromatase(13)
- CRTH2(2)
- Estrogen/progestogen Receptor(147)
- GnRH(26)
- Opioid Receptor(175)
- RAAS(8)
- Thyroid hormone Receptor(59)
- TRH(2)
- ROR/RAR/RXR(94)
- FXR & LXR(69)
- Glucocorticoids & Mineralocorticoids(49)
- GPR(1)
Products for Endocrinology and Hormones
- Cat.No. Product Name Information
- GC12126 Flutamide Androgen receptor antagonists
- GC48831 Flutamide-d7 An internal standard for the quantification of flutamide
- GC45455 Fluticasone 17β-Carboxylic Acid
- GC12815 Formestane Type I steroidal aromatase inhibitor
- GC60857 Frakefamide TFA Frakefamide TFA is a potent analgesic that acts as a peripheral active μ-selective receptor agonist.
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GC18000
Fulvestrant (ICI 182,780)
Fulvestrant is a selective estrogen receptor (ER) antagonist. It binds, blocks and degrades ER, then inhibits ER-mediated transcriptional activity with an IC50 of 9.4 nM.
- GC49878 Fulvestrant 9-sulfone An estrogen receptor antagonist and a derivative of fulvestrant
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GC12766
G-1
G-1 is a selective and potent agonist of GPR30 with EC50 value about 2 nM.
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GC16618
G-15
A GPER receptor antagonist
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GC14902
G-36
GPER activator
- GC43736 Ganirelix (acetate) Ganirelix is a gonadotropin-releasing hormone receptor (GNRHR) antagonist (IC50 = 3.6 nM; pA2 = 9.3).
- GC49303 Ganoderic Acid DM A triterpenoid with diverse biological activities
- GC10017 Gestodene Progestogen hormonal contraceptive
- GC48763 Gestodene-d6 An internal standard for the quantification of gestodene
- GC52506 Ghrelin (human) (trifluoroacetate salt) A growth hormone releasing peptide
- GC43754 Ghrelin (rat) (trifluoroacetate salt) Ghrelin is an endogenous gastrointestinal hormone and neuropeptide that binds to the growth hormone (GH) secretagogue receptor (GHS-R).
- GC45459 GHRP-6 (acetate)
- GC45462 GLP-1 (1-36) amide (human, rat) (trifluoroacetate salt)
- GC43764 GLP-2 (human) (trifluoroacetate salt) Glucagon-like peptide-2 (GLP-2) is an endogenous peptide hormone formed in L cells of the small and large intestine by cleavage of proglucagon in response to nutrient ingestion.
- GC30086 GLPG0492 A selective androgen receptor modulator
- GC30101 GLPG0492 R enantiomer GLPG0492 R enantiomer is the R enantiomer of GLPG-0492, which is a novel selective androgen receptor modulator.
- GP10122 Glucagon (19-29), human
- GC52490 Glucagon (hydrochloride) A peptide hormone
- GC49342 Glucagon-d9 (trifluoroacetate salt) An internal standard for the quantification of glucagon
- GC40049 Glucocorticoid Resistance Inhibitor Glucocorticoid resistance inhibitor is an inhibitor of glucocorticoid resistance.
- GC62992 Glutaurine Glutaurine containing glutamine and taurine residues is an orally active hormone of the parathyroid.
- GC30328 Gluten Exorphin C Gluten exorphin C is an opioid peptide derived from wheat gluten.
- GC40911 Glycine-β-muricholic Acid Glycine-β-muricholic Acid, a bile acid, is a potent, sable, intestine-selective and oral bioactive farnesoid X receptor (FXR) inhibitor that may be a candidate for the treatment of metabolic disorders.
- GC45466 Glyco-Obeticholic Acid
- GC62644 GnRH antagonist 2 GnRH antagonist 2 (formula I) is a GnRH receptor antagonist that can be used for endometriosis research.
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GP10043
GnRH Associated Peptide (GAP) (1-13), human
Inhibitor of prolactin secretion
- GC15843 GNTI dihydrochloride κ opioid receptor antagonist
- GC34001 Gonadorelin acetate A tropic hormone
- GC36180 Goserelin acetate A synthetic GNRH agonist
- GC14739 GR 89696 fumarate κ-opioid agonist
- GP10024 Growth Hormone (1-43), human Human Growth Hormone (1-43) peptide
- GC43785 GRP (porcine) (trifluoroacetate salt) Gastrin-releasing peptide (GRP) is a neuropeptide that stimulates gastrin release.
- GC10558 GSK 4716 estrogen-related receptors ERRβ and ERRγ agonist
- GC68427 GSK1521498 free base
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GC31331
GSK2033
An antagonist of LXRα and LXRβ
- GC17679 GSK2881078 selective androgen receptor modulator (SARM)
- GC48610 GSK3987 A dual agonist of LXRα and LXRβ
- GC45678 Guanoclor A guanidinium antihypertensive
- GC49048 Guanylin (human) (trifluoroacetate salt) A peptide hormone activator of GC-C
- GC17658 Guggulsterone Broad spectrum steroid receptor ligand
- GC16964 GW3965 An orally-active agonist of LXRα and LXRβ
- GC17696 GW3965 HCl GW3965 HCl is a potent and selective liver X receptor (LXR) agonist with EC50s of 190 nM and 30 nM for hLXRα and hLXRβ, respectively.
- GC10975 GW4064 GW4064, as a synthetic FXR agonist, was used for treatment of cholestatic liver diseases, metabolic syndrome and alcoholic liver disease.
- GA22290 H-D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH₂ CTAP, an analog of CTOP, is a selective µ-opioid receptor antagonist.
- GC49385 Halometasone A synthetic corticosteroid
- GC14221 HE-3235 HE-3235, synthetic analogue of 3β-androstanediol, is an orally bioavailable anticancer agent. HE-3235 is active in rodent models of prostate and breast cancer.
- GC43808 Hecogenin Acetate Hecogenin acetate is a steroid sapogenin and an acetylated form of hecogenin that has anthelmintic and antinociceptive properties.
- GC32489 Hemorphin-7 Hemorphin-7 is a hemorphin peptide, an endogenous opioid peptide derived from the β-chain of hemoglobin.
- GC15324 Hexestrol Estrogen receptor agonist
- GC43866 Histrelin (acetate) Histrelin is a synthetic gonadotropin-releasing hormone (GNRH) agonist that binds to the GNRH receptor (GNRHR; Ki = 0.2 nM in CHO cells expressing the human receptor).
- GC62249 Honokiol DCA
- GC43873 Hydrocortisone 21-hemisuccinate (sodium salt) Hydrocortisone 21-hemisuccinate is a water-soluble form of the endogenous hormone cortisol.
- GC52043 Hydrocortisone Aceponate Hydrocortisone aceponate (Hydrocortisone 17-propionate 21-acetate) is a potent topical glucocorticoid.
- GC47440 Hydrocortisone-d4 An internal standard for the quantification of hydrocortisone
- GC15599 Hydroxyprogesterone caproate synthetic progestational agent
- GC11639 ICI 154,129 Selective δ opioid antagonist
- GC16193 ICI 174,864 Selective δ opioid antagonist
- GC12534 ICI 199,441 hydrochloride ICI 199,441 hydrochloride is a potent and selective κ-opioid receptor agonist.
- GC13097 ICI 204,448 hydrochloride κ opioid receptor agonist
- GC50201 IHR 1 Potent Smo antagonist
- GC13078 Imidapril HCl Imidapril HCl (TA-6366) is an orally active angiotensin-converting enzyme (ACE) and MMP-9 inhibitor.
- GC32742 INT-767 INT-767 is a dual farnesoid X receptor (FXR)/TGR5 agonist with mean EC50s of 30 and 630 nM, respectively.
- GC49634 Isoflupredone Isoflupredone belongs to the class of corticosteroids and exerts its effect by binding to glucocorticoid and mineralocorticoid receptors of animals, such as horses.
- GC49306 Isopimaric Acid A diterpenoid resin acid
- GC36344 Isosilybin B Isosilybin B, a flavonolignan isolated from silymarin, has anti-prostate cancer (PCA) activity via inhibiting proliferation and inducing G1 phase arrest and apoptosis. Isosilybin B causes androgen receptor (AR) degradation.
- GC15382 Isotretinoin A retinoid
- GC47474 Itraconazole-d5 An internal standard for the quantification of itraconazole
- GC17939 JDTic
- GC17624 JDTic 2HCl
- GC43929 JMV3002 Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor that stimulates food intake and transduces signals to hypothalamic regulatory nuclei that control energy homeostasis.
- GC62106 JNJ-63576253 JNJ-63576253 (TRC-253) is a potent and orally active full antagonist of androgen receptor (AR), with IC50s of 37 and 54 nM for F877L mutant AR and wild-type AR in LNCaP cells. JNJ-63576253 can be used for the research of castration-resistant prostate cancer (CRPC).
- GC11826 JTC-801 KOR-3 (NOP) receptor antagonist
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GC43934
Juvenile Hormone III
Juvenile hormone III is an acyclic sesquiterpenoid that regulates diverse processes in insects, including adult transition of larvae and oogenesis in adult females.
- GC31616 KAT681 (T0681) KAT681 (T0681) is a liver-selective thyromimetic.
- GC48432 KB-130015 An antiarrhythmic agent
- GC31151 Kelatorphan Kelatorphan is a full inhibitor of enkephalin degrading enzymes.
- GC40109 Ketoconazole-d3 Ketoconazole-d3 is intended for use as an internal standard for the quantification of ketoconazole by GC- or LC-MS.
- GC45490 Kisspeptin-54 (human) (trifluoroacetate salt)
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GC11268
L-Thyroxine
Iodine containing hormone
- GC61010 L-Thyroxine sodium L-Thyroxine sodium (Levothyroxine sodium) is a synthetic hormone for the research of hypothyroidism.
- GC36487 L-Thyroxine sodium salt pentahydrate L-Thyroxine sodium salt pentahydrate (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism.
- GC44088 L-Thyroxine-13C9,15N L-Thyroxine-13C9,15N is intended for use as an internal standard for the quantification of L-thyroxine by GC- or LC-MS.
- GC52021 L-Thyroxine-N-methylamide A potential impurity found in commercial preparations of L-thyroxine
- GC48937 L-Tyrosine-13C9,15N An internal standard for the quantification of L-tyrosine
- GC65936 Larsucosterol (trimethylamine) Larsucosterol (DUR-928) trimethylamine, a cholesterol metabolite, is a potent liver X receptor (LXR) antagonist. Larsucosterol trimethylamine as a potent endogenous regulator decreases lipogenesis. Larsucosterol trimethylamine inhibits the cholesterol biosynthesis via decreasing mRNA levels and inhibiting the activation of SREBP-1.
- GC44036 Lasofoxifene Lasofoxifene is a third-generation, non-steroidal selective estrogen receptor modulator (SERM).
- GC11425 Lasofoxifene (tartrate) third-generation, non-steroidal selective estrogen receptor modulator (SERM)
- GC12294 LE 135 RARβ antagonist
- GC33034 Lecirelin Lecirelin, a synthetic gonadotropin-releasing hormone (GnRH) analogue, acts as a GnRH agonist.
- GC18496 Leelamine (hydrochloride) Leelamine is a diterpene molecule whose name derives from the Sanskrit word leela which means 'play'- It has weak affinity for the human central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, exhibiting 20% displacement of [3H]-CP55940 at a concentration of 10 uM.
- GP10031 Leptin (116-130) amide (mouse)
- GC10726 Letrozole Non-steroidal aromatase inhibitor
- GC47554 Letrozole-d4 An internal standard for the quantification of letrozole
- GC10076 Leuprolide Acetate A synthetic GnRH receptor agonist
- GC14704 Levonorgestrel Estrogen/progestogen receptor agonist