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Home >> Signaling Pathways >> Proteases

Proteases

Proteases is a general term for a class of enzymes that hydrolyze protein peptide chains. According to the way they degrade polypeptides, they are divided into two categories: endopeptidases and telopeptidases. The former can cut the large molecular weight polypeptide chain from the middle to form prions and peptones with smaller molecular weights; the latter can be divided into carboxypeptidase and aminopeptidase, which respectively remove the peptide from the free carboxyl terminus or free amino terminus of the polypeptide one by one. Chain hydrolysis produces amino acids.

A general term for a class of enzymes that hydrolyze peptide bonds in proteins. According to the way they hydrolyze polypeptides, they can be divided into endopeptidases and exopeptidases. Endopeptidase cleaves the interior of the protein molecule to form smaller molecular weight peptones and peptones. Exopeptidase hydrolyzes peptide bonds one by one from the end of the free amino group or carboxyl group of protein molecules, and frees amino acids, the former is aminopeptidase and the latter is carboxypeptidase. Proteases can be classified into serine proteases, sulfhydryl proteases, metalloproteases and aspartic proteases according to their active centers and optimum pH. According to the optimum pH value of its reaction, it is divided into acidic protease, neutral protease and alkaline protease. The proteases used in industrial production are mainly endopeptidases.

Proteases are widely found in animal offal, plant stems and leaves, fruits and microorganisms. Microbial proteases are mainly produced by molds and bacteria, followed by yeast and actinomycetes.

Enzymes that catalyze the hydrolysis of proteins. There are many kinds, the important ones are pepsin, trypsin, cathepsin, papain and subtilisin. Proteases have strict selectivity for the reaction substrates they act on. A protease can only act on certain peptide bonds in protein molecules, such as the peptide bonds formed by the hydrolysis of basic amino acids catalyzed by trypsin. Proteases are widely distributed, mainly in the digestive tract of humans and animals, and are abundant in plants and microorganisms. Due to limited animal and plant resources, the industrial production of protease preparations is mainly prepared by fermentation of microorganisms such as Bacillus subtilis and Aspergillus terrestris.

Targets for  Proteases

Products for  Proteases

  1. Cat.No. Product Name Information
  2. GC39474 7-Ketolithocholic acid

    7-KLCA, 7-keto LCA, 7-oxo LCA, 7-keto Lithocholate, 7-oxo Lithocholate, 7-oxo Lithocholic Acid, NSC 226118

     7-Ketolithocholic acid (3α-hydroxy-7-oxygen-5β-cholic acid) is a kind of bile acid, 7-Ketolithocholic acid can be absorbed, 7-ketolithocholic acid inhibits the production of endogenous bile acid, and can affect the secretion of biliary cholestero. 7-Ketolithocholic acid Chemical Structure
  3. GC33616 7-Methylguanine

    Epiguanine, 2-Amino-7-methylhypoxanthine, N7-Methylguanine, NSC 193444, NSC 19647

     7-Methylguanine is a metabolite of DNA methylation. 7-Methylguanine Chemical Structure
  4. GC62817 7-Methylguanosine 5’-diphosphate sodium

    7-Methyl-GDP sodium; m7GDP sodium

     7-Methylguanosine 5'-diphosphate (7-Methyl-GDP) sodium, a cap analog, can be used in the synthesis of mRNA cap analogues. 7-Methylguanosine 5’-diphosphate sodium Chemical Structure
  5. GC31617 7-Methylxanthine

    7-MX, NSC 7861

     7-Methylxanthine, a methyl derivative of xanthine, is one of the purine components in urinary calculi. 7-Methylxanthine Chemical Structure
  6. GC14433 7α,25-dihydroxy Cholesterol

    7α,25-DHC

     A GPR183 agonist 7α,25-dihydroxy Cholesterol Chemical Structure
  7. GC40462 8(R)-HETE

    8(R)-Hydroxyeicosatetraenoic Acid

     8(R)-HETE is biosynthesized by lipoxygenation of arachidonic acid in marine invertebrates such as gorgonian corals and starfish. 8(R)-HETE Chemical Structure
  8. GC41136 8(S),15(S)-DiHETE 8(S),15(S)-DiHETE is formed when 15(S)-HETE is subjected to further oxidation by 15-LO. 8(S),15(S)-DiHETE Chemical Structure
  9. GC40382 8(S)-HEPE 8(S)-HEPE is a monohydroxy fatty acid produced by lipoxygenase oxidation of EPA. 8(S)-HEPE Chemical Structure
  10. GC40463 8(S)-HETE

    8(S)-Hydroxyeicosatetraenoic Acid

     8(S)-HETE is a major lipoxygenase product in PMA-treated murine epidermis. 8(S)-HETE Chemical Structure
  11. GC42619 8(S)-HETrE 8(S)-HETrE is a monohydroxy polyunsaturated fatty acid produced by rabbit neutrophil lipoxygenase when dihomo-γ-linolenic acid is used as a substrate. 8(S)-HETrE Chemical Structure
  12. GC18544 8-dehydro Cholesterol

    8-dehydro Cholesterol (8-DHC) is an isomer of the cholesterol precursor 7-DHC .

     8-dehydro Cholesterol Chemical Structure
  13. GC60541 8-Demethyl Ivabradine 8-Demethyl Ivabradine is a metabolite of Ivabradine. 8-Demethyl Ivabradine Chemical Structure
  14. GC49017 8-hydroxy Amoxapine A metabolite of amoxapine 8-hydroxy Amoxapine Chemical Structure
  15. GC42626 8-hydroxy Efavirenz 8-hydroxy Efavirenz is a major oxidative metabolite of the non-nucleoside reverse transcriptase inhibitor efavirenz. 8-hydroxy Efavirenz Chemical Structure
  16. GC18654 8-hydroxy Loxapine

    8-OH Loxapine

     8-hydroxy Loxapine (8-OH loxapine) is a metabolite formed when loxapine , an atypical antipsychotic, is metabolized by the cytochrome P450 isoform CYP1A2. 8-hydroxy Loxapine Chemical Structure
  17. GC49544 8-hydroxy Mirtazapine

    8-hydroxy-6-Azamianserin

     A metabolite of mirtazapine 8-hydroxy Mirtazapine Chemical Structure
  18. GC40926 8-Hydroxy-2'-deoxyguanosine

    8-OHdG

     8-Hydroxy-2'-deoxyguanosine is produced by oxidative damage of DNA by reactive oxygen and nitrogen species, including hydroxyl radical and peroxynitrite. 8-Hydroxy-2'-deoxyguanosine Chemical Structure
  19. GC35204 8-Hydroxyguanine 8-Hydroxyguanine is a major pre-mutagenic lesion generated from reactive oxygen species. 8-Hydroxyguanine Chemical Structure
  20. GC31219 8-Hydroxyguanosine

    7,8-Dihydro-8-oxoguanosine, 8-oxo-G, NSC 90393, 8-OHG

     Product of oxidative damage to RNA 8-Hydroxyguanosine Chemical Structure
  21. GC18515 8-iso Prostaglandin F2α

    iPF2α-III, 8-iso-15(S)-Prostaglandin F2α, 8-Isoprostane, 8-epi PGF2α, 15-F2t-Isoprostane

     8-iso PGF2α is an isoprostane produced by the non-enzymatic peroxidation of arachidonic acid in membrane phospholipids. 8-iso Prostaglandin F2α Chemical Structure
  22. GC18994 8-iso Prostaglandin F2β

    iPF2α-III, 8-iso-15(S)-Prostaglandin F2α, 8-Isoprostane, 8-epi PGF2α, 15-F2t-Isoprostane

     8-iso Prostaglandin F2β (8-iso PGF2β) is an isomer of PGF2α with a non-enzymatic, non-cyclooxygenase origin. 8-iso Prostaglandin F2β Chemical Structure
  23. GC41642 9(E),11(E),13(E)-Octadecatrienoic Acid

    β-Eleostearic Acid, β-ESA

     9(E),11(E),13(E)-Octadecatrienoic acid (β-ESA) is a conjugated polyunsaturated fatty acid that is found in plant seed oils and in mixtures of conjugated linolenic acids synthesized by the alkaline isomerization of linolenic acid. 9(E),11(E),13(E)-Octadecatrienoic Acid Chemical Structure
  24. GC42633 9(E)-Erythromycin A oxime (9E)-Erythromycin A oxime is a metabolite of the semisynthetic antibiotic roxithromycin . 9(E)-Erythromycin A oxime Chemical Structure
  25. GC40542 9(R)-HODE

    9(R)-Hydroxyoctadecadienoic Acid

     9(R)-HODE is one of several monohydroxylated products of linoleic acid. 9(R)-HODE Chemical Structure
  26. GC40029 9(S),10(S),13(S)-TriHOME 9(S),10(S),13(S)-TriHOME is an oxylipin derived from linoleic acid. 9(S),10(S),13(S)-TriHOME Chemical Structure
  27. GC46753 9(S),12(S),13(S)-TriHOME

    (–)-Pinellic Acid, 9S,12S,13S-Pinellic Acid

     An oxylipin 9(S),12(S),13(S)-TriHOME Chemical Structure
  28. GC40383 9(S)-HEPE 9(S)-HEPE is a monohydroxy fatty acid derived from EPA. 9(S)-HEPE Chemical Structure
  29. GC19460 9(S)-HODE 9(S)-HODE is produced by the lipoxygenation of linoleic acid in both plants and animals. 9(S)-HODE Chemical Structure
  30. GC40250 9(S)-HODE-d4 MaxSpec® Standard 9(S)-HODE-d4 is intended for use as an internal standard for the quantification of 9(S)-HODE by GC- or LC-mass spectrometry. 9(S)-HODE-d4 MaxSpec® Standard Chemical Structure
  31. GC42636 9(S)-HOTrE 9(S)-HOTrE is a monohydroxy polyunsaturated fatty acid produced by the action of 5-lipoxygenase on α-linolenic acid. 9(S)-HOTrE Chemical Structure
  32. GC40357 9(S)-HpODE 9(S)-HpODE is produced by the action of arachidonate 5-LO on linoleic acid. 9(S)-HpODE Chemical Structure
  33. GC42637 9(S)-HpOTrE 9(S)-HpOTrE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 5-lipoxygenase (5-LO) on α-linolenic acid. 9(S)-HpOTrE Chemical Structure
  34. GC18389 9-cis Retinal

    9-cis Retinaldehyde, 9-cis Vitamin A aldehyde

     9-cis Retinal is a natural retinoid that is produced by oxidation of 9-cis retinol by cis-retinol dehydrogenase (cRDH). 9-cis Retinal Chemical Structure
  35. GC38883 9-Ethyladenine 9-Ethyladenine is a partially effective inhibitor of APRT (adenine phosphoribosyltransferase). 9-Ethyladenine Chemical Structure
  36. GC42651 9-oxo-10(E),12(E)-Octadecadienoic Acid

    9-oxo ODA

     9-oxo-10(E),12(E)-Octadecadienoic acid (9-oxoODA) is a natural agonist, abundant in tomatoes, that activates PPARα at 10-20 μM. 9-oxo-10(E),12(E)-Octadecadienoic Acid Chemical Structure
  37. GC42653 9-OxoOTrE

    9KOTE, 9KOTrE

     9-OxoOTrE is produced by the oxidation of 9-HpOTrE. 9-OxoOTrE Chemical Structure
  38. GC45960 9c(i472)

    15-LOX-1 Inhibitor i472

     9c(i472) is a potent inhibitor of 15-LOX-1 (15-lipoxygenase-1) with an IC50 value of 0.19 μM. 9c(i472) Chemical Structure
  39. GC62859 Aβ42-IN-2 Aβ42-IN-2 is a γ-secretase modulator extracted from patent WO2016070107, compound example 36. Aβ42-IN-2 Chemical Structure
  40. GC31938 A-69412 A-69412 is a reversible, specific inhibitor of the 5-lipoxygenase (5-LO). A-69412 Chemical Structure
  41. GC68587 A-908292

    A-908292 is an effective and selective inhibitor of acetyl-CoA carboxylase 2 (ACC2), with an IC50 value of 23 nM for hACC2. A-908292 can be used in the study of fatty acid metabolism.

     A-908292 Chemical Structure
  42. GC15614 A922500

    (1R,2R)2(4'(3phenylureido)biphenylcarbonyl)cyclopentanecarboxylic acid

     A diacylglycerol acyltransferase 1 inhibitor A922500 Chemical Structure
  43. GC42665 AAF-CMK (trifluoroacetate salt)

    NAlaAlaPheCMK, Tripeptidyl Peptidase Inhibitor II

     Tripeptidyl peptidase II (TPPII) is a serine peptidase of the subtilisin-type which removes tripeptides from the free NH2 terminus of oligopeptides. AAF-CMK (trifluoroacetate salt) Chemical Structure
  44. GC42667 Abacavir Carboxylate Abacavir carboxylate is an inactive metabolite of the HIV-1 reverse transcriptase inhibitor abacavir. Abacavir Carboxylate Chemical Structure
  45. GC46769 Abametapir

    5,5′-Dimethyl-2,2′-dipyridyl

     A building block and an insecticide Abametapir Chemical Structure
  46. GC35219 Abiraterone metabolite 1

    3β-OH-5α-Abi

     Abiraterone metabolite 1 is a 5β-reduced metabolite of abiraterone. Abiraterone, a steroidal drug, inhibits CYP17A1, blocks androgen synthesis and prolongs survival in prostate cancer. Abiraterone metabolite 1 Chemical Structure
  47. GC67766 Abiraterone sulfate Abiraterone sulfate Chemical Structure
  48. GC35221 ABT-046 ABT-046 is a potent, selective, and orally active acyl CoA:diacylglycerol acyltransferase 1 (DGAT-1) inhibitor with IC50s of both 8 nM against human and mouse DGAT-1. ABT-046 Chemical Structure
  49. GC60548 ABT-100 ABT-100 is a potent, highly selective and orally active farnesyltransferase inhibitor. ABT-100 inhibits cell proliferation (IC50s of 2.2 nM, 3.8 nM, 5.9 nM, 6.9 nM, 9.2 nM, 70 nM and 818 nM for EJ-1, DLD-1, MDA-MB-231, HCT-116, MiaPaCa-2, PC-3, and DU-145 cells, respectively), increases apoptosis and decreases angiogenesis. ABT-100 possesses broad-spectrum antitumor activity. ABT-100 Chemical Structure
  50. GC38264 Ac-Ala-OH Ac-Ala-OH Chemical Structure
  51. GA11174 Ac-Arg-OH.2H2O Ac-Arg-OH.2H2O Chemical Structure
  52. GA20489 Ac-Asn-OH Ac-Asn-OH is an endogenous metabolite. Ac-Asn-OH Chemical Structure
  53. GC17602 Ac-DEVD-AFC

    N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-Trifluoromethylcoumarin,Caspase-3 Substrate (Fluorogenic)

     fluorogenic substrate for activated caspase-3 Ac-DEVD-AFC Chemical Structure
  54. GC32695 Ac-DEVD-CHO Ac-DEVD-CHO is a Caspase-3 inhibitor with an IC50 value of 0.016μM. Ac-DEVD-CHO Chemical Structure
  55. GC10951 Ac-DEVD-CMK

    Ac-Asp-Glu-Val-Asp-CMK,Caspase-3 Inhibitor III

     cell-permeable, and irreversible inhibitor of caspase Ac-DEVD-CMK Chemical Structure
  56. GA10446 Ac-DL-Trp-OH Ac-DL-Trp-OH Chemical Structure
  57. GC60558 Ac-FLTD-CMK Ac-FLTD-CMK, a gasdermin D (GSDMD)-derived inhibitor, is a specific inflammatory caspases inhibitor. Ac-FLTD-CMK Chemical Structure
  58. GC49704 Ac-FLTD-CMK (trifluoroacetate salt)

    Ac-Phe-Leu-Thr-Asp-CMK

     An inhibitor of caspase-1, -4, -5, and -11 Ac-FLTD-CMK (trifluoroacetate salt) Chemical Structure
  59. GA10356 Ac-Gly-OH Ac-Gly-OH Chemical Structure
  60. GA10825 Ac-His-OH Ac-His-OH Ac-His-OH Chemical Structure
  61. GC10258 Ac-IEPD-AFC Ac-IEPD-AFC Chemical Structure
  62. GC10968 Ac-LEHD-AFC A caspase-4, -5, and -9 fluorogenic substrate Ac-LEHD-AFC Chemical Structure
  63. GA20612 Ac-Lys-OH Ac-Lys-OH is an endogenous metabolite. Ac-Lys-OH Chemical Structure
  64. GA20680 Ac-Val-OH Ac-Val-OH Chemical Structure
  65. GC31548 ACAT-IN-1 cis isomer ACAT-IN-1 cis isomer is a potent ACAT inhibitor with an IC50 of 100 nM. ACAT-IN-1 cis isomer Chemical Structure
  66. GC42690 Acecainide (hydrochloride)

    N-Acetylprocainamide

     Acecainide is an active metabolite of the class III antiarrhythmic procainamide. Acecainide (hydrochloride) Chemical Structure
  67. GC35228 Aceglutamide

    Aceglutamide, Acetylglutamine, N-acetyl Gln, NSC 186896

     Aceglutamide (α-N-Acetyl-L-glutamine) is a psychostimulant and nootropic, used to improve memory and concentration. Aceglutamide Chemical Structure
  68. GC46779 Acequinocyl A naphthoquinone acaricide Acequinocyl Chemical Structure
  69. GC38317 Acetamide Acetamide is used as an intermediate in the synthesis of methylamine, thioacetamide, and insecticides, and as a plasticizer in leather, cloth and coatings. Acetamide has carcinogenicity. Acetamide Chemical Structure
  70. GC12917 Acetaminophen

    4-Acetamidophenol, APAP, 4'-Hydroxyacetanilide, NSC 3991, NSC 109028, Paracetamol

    A COX inhibitor

     Acetaminophen Chemical Structure
  71. GC62824 Acetaminophen glucuronide

    Acetaminophen glucuronide (APAP-glu) is an inactive glucuronide metabolite of Acetaminophen.

     Acetaminophen glucuronide Chemical Structure
  72. GC42693 Acetaminophen Glucuronide (sodium salt)

    4-Acetamidophenol Glucuronide, APAP Glucuronide, 4'-Hydroxyacetanilide Glucuronide, Paracetamol Glucuronide

     Acetaminophen glucuronide is an inactive metabolite of the analgesic and antipyretic agent acetaminophen. Acetaminophen Glucuronide (sodium salt) Chemical Structure
  73. GC33558 Acetaminophen metabolite 3-hydroxy-acetaminophen (3-Hydroxyacetaminophen) 3-hydroxy-acetaminophen is a metabolite of Acetaminophen, which is a pain medicine. Acetaminophen metabolite 3-hydroxy-acetaminophen (3-Hydroxyacetaminophen) Chemical Structure
  74. GC42694 Acetaminophen sulfate (potassium salt)

    4-Acetamidophenol sulfate, APAP sulfate, 4'-Hydroxyacetanilide sulfate, Paracetamol sulfate

     Acetaminophen sulfate is a metabolite of acetaminophen. Acetaminophen sulfate (potassium salt) Chemical Structure
  75. GC64137 Acetaminophen-d3 Acetaminophen-d3 Chemical Structure
  76. GC42695 Acetoacetyl Coenzyme A (sodium salt hydrate)

    Acetoacetyl-CoA

    Acetoacetyl coenzyme A (acetoacetyl-CoA) is a precursor to HMG-CoA in the isoprenoid pathway.

     Acetoacetyl Coenzyme A (sodium salt hydrate) Chemical Structure
  77. GC42697 Acetyl Coenzyme A (sodium salt)

    AcetylCoA

     Acetyl-coenzyme A (Acetyl-CoA) trisodium is a membrane-impermeant central metabolic intermediate, participates in the TCA cycle and oxidative phosphorylation metabolism. Acetyl Coenzyme A (sodium salt) Chemical Structure
  78. GC60555 Acetyl phosphate(lithium potassium) Acetyl phosphate(lithium potassium) is an endogenous metabolite. Acetyl phosphate(lithium potassium) Chemical Structure
  79. GC12152 Acetyl-Calpastatin (184-210) (human) Acetyl-Calpastatin (184-210) (human) Chemical Structure
  80. GC46789 Acetyl-L-carnitine-d3 (chloride)

    ALCAR-d3, L-Acetylcarnitine-d3, C2:0 Carnitine-d3, CAR 2:0-d3, L-Carnitine acetyl ester-d3

     An internal standard for the quantification of L-acetylcarnitine Acetyl-L-carnitine-d3 (chloride) Chemical Structure
  81. GC68097 Acetyl-L-carnitine-d3 hydrochloride

    O-Acetyl-L-carnitine-d3 hydrochloride

     Acetyl-L-carnitine-d3 hydrochloride Chemical Structure
  82. GC14142 Acetylcholine Chloride

    ACh

     Major transmitter at many nervous sites Acetylcholine Chloride Chemical Structure
  83. GC11786 Acetylcysteine

    N-acetylcysteine; N-acetyl-L-cysteine; NAC; Acetadote

     Acetylcysteine is the N-acetyl derivative of CYSTEINE. Acetylcysteine Chemical Structure
  84. GC32305 ACH-806 (GS9132)

    GS9132

     ACH-806 (GS9132) is an NS4A antagonist which can inhibit Hepatitis C Virus (HCV) replication with an EC50 of 14 nM. ACH-806 (GS9132) Chemical Structure
  85. GC49406 ACT-373898 A metabolite of macitentan ACT-373898 Chemical Structure
  86. GC16350 Actinonin

    (-)-Actinonin,Ro 06-1467

    Peptidomimetic antibiotic that inhibits aminopeptidases

     Actinonin Chemical Structure
  87. GC46798 Adapalene-d3 An internal standard for the quantification of adapalene Adapalene-d3 Chemical Structure
  88. GC13432 Adenine High affinity adenine receptor agonist Adenine Chemical Structure
  89. GC62828 Adenine monohydrochloride hemihydrate Adenine monohydrochloride hemihydrate is an endogenous metabolite. Adenine monohydrochloride hemihydrate Chemical Structure
  90. GC17278 Adenine sulfate Adenine sulfate (6-Aminopurine hemisulfate), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine sulfate acts as a chemical component of DNA and RNA. Adenine sulfate also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis. Adenine sulfate Chemical Structure
  91. GC14106 Adenosine

    NSC 7652

     nucleoside Adenosine Chemical Structure
  92. GC19630 Adenosine 2′-monophosphate Adenosine 2′-monophosphate (2'-AMP) is converted by extracellular 2',3'-CAMP. Adenosine 2′-monophosphate Chemical Structure
  93. GC10880 Adenosine 3-5-cyclic monophosphate

    Adenosine 3',5'-cyclic monophosphate, cAMP, Cyclic adenosine monophosphate, NSC 94017, NSC 143670

     A second messenger Adenosine 3-5-cyclic monophosphate Chemical Structure
  94. GC17558 Adenosine 5'-triphosphate disodium salt hydrate

    ATP disodium salt hydrate

     Adenosine 5'-triphosphate disodium salt hydrate (Adenosine 5'-triphosphatedisodium salt hydrate) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. Adenosine 5'-triphosphate disodium salt hydrate Chemical Structure
  95. GC13172 Adenosine 5-monophosphate

    AMP

     Adenosine 5-monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction. Adenosine 5-monophosphate Chemical Structure
  96. GC11969 Adenosine-5'-diphosphate

    Adenosine Pyrophosphate,ADP,5′-ADP

     Agonist of purinergic receptors Adenosine-5'-diphosphate Chemical Structure
  97. GC64916 Adenylosuccinic acid tetraammonium

    Adenylosuccinate tetraammonium; Aspartyl adenylate tetraammonium

     Adenylosuccinic acid tetraammonium (Adenylosuccinate; Aspartyl adenylate) is a purine ribonucleoside monophosphate and plays a role in nucleotide cycle metabolite. Adenylosuccinic acid tetraammonium Chemical Structure
  98. GC63661 Aderbasib Aderbasib (INCB007839) is a potent, orally active and target specific low nanomolar hydroxamate-based inhibitor of ADAM10 and ADAM17. Aderbasib exhibits robust antineoplastic activity and can be used for cancer research, including diffuse large B-cell non-Hodgkin lymphoma, HER2+?breast cancer, gliomas, et al. Aderbasib Chemical Structure
  99. GC33805 Adipic acid Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism. Adipic acid Chemical Structure
  100. GC19021 Adjudin

    AF-2364

     Adjudin is an extensively studied male contraceptive with a superior mitochondria-inhibitory effect. Adjudin Chemical Structure
  101. GC49216 ADL 08-0011 (hydrochloride) An active metabolite of alvimopan ADL 08-0011 (hydrochloride) Chemical Structure

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