DNA Damage/DNA Repair
- MTH1(4)
- PARP(69)
- ATM/ATR(27)
- DNA Alkylating(18)
- DNA Ligases(3)
- DNA Methyltransferase(21)
- DNA-PK(29)
- HDAC(124)
- Nucleoside Antimetabolite/Analogue(107)
- Telomerase(14)
- Topoisomerase(128)
- tankyrase(5)
- Antifolate(28)
- CDK(209)
- Checkpoint Kinase (Chk)(28)
- CRISPR/Cas9(8)
- Deubiquitinase(45)
- DNA Alkylator/Crosslinker(62)
- DNA/RNA Synthesis(327)
- Eukaryotic Initiation Factor (eIF)(16)
- IRE1(22)
- LIM Kinase (LIMK)(8)
- TOPK(5)
- Casein Kinase(50)
- DNA Intercalating Agents(6)
- DNA/RNA Oxidative Damage(11)
Products for DNA Damage/DNA Repair
- Cat.No. Product Name Information
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GC19566
N-Nitrosodiethylamine
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GC31365
γ-Oryzanol
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GC38194
(±)-10-Hydroxycamptothecin
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GC33107
(±)-BAY-1251152
-
GC10867
(+)-Aphidicolin
Tetracyclic diterpene antibiotic
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GC32429
(-)-BAY-1251152
-
GC40076
(-)-Voacangarine
(-)-Voacangarine is an indole alkaloid originally isolated from V.
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GC38377
(2S,3R)-Voruciclib hydrochloride
-
GC41695
(6R,S)-5,6,7,8-Tetrahydrofolic Acid (hydrochloride)
(6R,S)-5,6,7,8-Tetrahydrofolic acid (THFA), the reduced form of folic acid, serves as a cofactor in methyltransferase reactions and is the major one-carbon carrier in one carbon metabolism.
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GC41088
(6S)-Tetrahydrofolic Acid
(6S)-Tetrahydrofolic acid is a diastereomer of tetrahydrofolic acid, a reduced form of folic acid that serves as a cofactor in methyltransferase reactions and is the major one-carbon carrier in one carbon metabolism.
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GC62735
(E/Z)-GO289
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GC64429
(E/Z)-Zotiraciclib citrate
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GC63864
(E/Z)-Zotiraciclib hydrochloride
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GC41716
(R)-CR8
Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy.
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GC39281
(R)-CR8 trihydrochloride
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GC64210
(R)-GSK-3685032
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GC41633
(R)-Prunasin
(R)-Prunasin is a cyanogenic glucoside that is the precursor to amygdalin, a bitter component found in species of the genera Prunus and Olinia.
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GC34124
(rel)-MC180295
-
GC10098
(S)-10-Hydroxycamptothecin
inhibitor of topoisomerase I
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GC34999
(S)-Ceralasertib
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GC13136
(S)-Crizotinib
Potent MTH1 inhibitor
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GC60421
(S)-Seco-Duocarmycin SA
-
GC39842
(Z)-4EGI-1
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GC19528
1,4-Benzoquinone
-
GC41859
1,5,7-Triazabicyclo[4.4.0]dec-5-ene
1,5,7-Triazabicyclo[4.4.0]dec-5-ene is a bicyclic guanidine base that can be used as a catalyst for a variety of base-mediated organic transformations, including Michael additions, Wittig reactions, Henry reactions, and transesterification reactions.
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GC49470
1-Ethyl-1-nitrosourea (hydrate)
A DNA alkylating agent
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GC63796
116-9e
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GC61667
2′-Deoxy-2′-fluoroadenosine
-
GC62530
2’-O-Me-C(Bz) Phosphoramidite
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GC62529
2’-OMe-A(Bz) Phosphoramidite
-
GC62531
2’-OMe-G(ibu) Phosphoramidite
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GC42061
2',3'-Dideoxyadenosine 5'-triphosphate
2',3'-Dideoxyadenosine 5'-triphosphate (ddATP) is an in vitro inhibitor of reverse transcriptases from retroviruses, including HIV-1 and visna (Kis = 20 and 37 nM, respectively).
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GC42151
2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)
2'-Deoxyguanosine 5'-monophosphate (dGMP) is used as a substrate of guanylate kinases to generate dGDP, which in turn is phosphorylated to dGTP, a nucleotide precursor used in DNA synthesis.
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GC33430
2'-Deoxypseudoisocytidine
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GC35072
2'-O,4'-C-Methyleneuridine
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GC42080
2'2'-cGAMP (sodium salt)
2'2'-cGAMP is a synthetic dinucleotide (CDN) that contains non-canonical 2'5'-phosphodiester bonds.
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GC64399
2,4,6-Trihydroxybenzoic acid
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GC60459
2,4-D (2,4-Dichlorophenoxyacetic acid)
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GC33496
2-(Methylamino)-1H-purin-6(7H)-one (N2-methylguanine)
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GC39527
2-O-Methylcytosine
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GC42197
2-Thiouridine
2-Thiouridine (s2U) is a modified nucleobase found in tRNAs that is known to stabilize U:A pairs and modestly destabilize U:G wobble pairs.
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GC40618
3',4',7-Trihydroxyisoflavone
3',4',7-Trihydroxyisoflavone is a natural isoflavonoid that has antioxidant activity.
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GC35105
3'-Azido-3'-deoxy-beta-L-uridine
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GC60023
3'-Deoxyuridine-5'-triphosphate
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GC61862
3'-Deoxyuridine-5'-triphosphate trisodium
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GC45332
3'-Dephosphocoenzyme A
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GC34384
3,6-DMAD hydrochloride
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GC34452
3,7,4'-Trihydroxyflavone
-
GC13510
3-AP
ribonucleotide reductase inhibitor and iron chelator with antitumor activity
-
GC15389
360A
G-quadruplex structures inhibitor
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GC10115
360A iodide
G-quadruplex structures inhibitor
-
GC14493
4μ8C
IRE1 Rnase inhibitor, potent and non-toxic
-
GC17271
4'-Demethylepipodophyllotoxin
Anti-cancer drug
-
GC11761
4-amino-1,8-Naphthalimide
PARP inhibitor
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GC16474
4-HQN
PARP inhibitor
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GC18853
4-isocyanato TEMPO
4-isocyanato TEMPO is a spin labeling reagent used to label the 2'-position in RNA.
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GC61683
4-Methoxyphenethyl alcohol
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GC42464
4-oxo-2-Nonenal
4-hydroxy Nonenal is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids such as arachidonic acid and linoleic acid.
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GC45353
4-oxo-27-TBDMS Withaferin A
-
GC40477
4-Thiouracil
4-Thiouracil is a site-specific, photoactivatable probe used to detect RNA structures and nucleic acid-nucleic acid contacts.
-
GC42474
4-Thiouridine
4-Thiouridine (4-SU) is a photoactivatable ribonucleoside analog that is widely used for RNA analysis, including short-range RNA-RNA crosslinking and nascent RNA labeling.
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GC13104
4E1RCat
Dual inhibitor of eIF4E:eIF4G and eIF4E:4E-BP1 interaction
-
GC30785
4E2RCat
-
GC10468
4EGI-1
Competitive eIF4E/eIF4G interaction inhibitor
-
GC12667
4SC-202
Class I HDAC inhibitor
-
GC62157
5’-O-DMT-2’-O-TBDMS-Ac-rC
-
GC62149
5’-O-DMT-2’-TBDMS-Uridine
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GC62532
5’-O-DMT-3’-O-TBDMS-Ac-rC
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GC62573
5’-O-DMT-Bz-rC
-
GC62574
5’-O-DMT-N4-Ac-2’-F-dC
-
GC62575
5’-O-DMT-N4-Bz-2’-F-dC
-
GC62576
5’-O-DMT-N4-Bz-5-Me-dC
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GC62812
5’-O-DMT-PAC-dA
-
GC62813
5’-O-DMT-rI
-
GC62577
5’-O-DMT-rU
-
GC62578
5’-O-TBDMS-Bz-dA
-
GC62579
5’-O-TBDMS-dA
-
GC62580
5’-O-TBDMS-dG
-
GC62581
5’-O-TBDMS-dT
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GC40641
5'-Ethynyl-2'-deoxycytidine
5'-Ethynyl-2'-deoxycytidine (EdC) is a nucleoside analog that inhibits replication of the herpes simplex virus-1 (HSV-1) KOS strain (ID50 = 0.2 μg/mL).
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GC61432
5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine
-
GC61726
5'-O-DMT-N4-Ac-dC
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GN10629
5,7-dihydroxychromone
Nrf2/ARE signal activator and PPARγ agonist
-
GC10946
5-Azacytidine
A DNA methyltransferase inhibitor
-
GC11940
5-BrdU
Synthetic thymidine analog
-
GC42545
5-Fluorouracil-13C,15N2
5-Fluorouracil-13C,15N2 is intended for use as an internal standard for the quantification of 5-flurouracil by GC- or LC-MS.
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GC46033
5-Heneicosylresorcinol
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GC62389
5-Iminodaunorubicin
-
GC31187
5-Methoxyflavone
-
GC42562
5-Methyl-2'-deoxycytidine
5-Methyl-2'-deoxycytidine is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in cis to signal de novo DNA methylation.
-
GC35166
5-Methylcytosine
-
GC62547
5-O-TBDMS-N4-Benzoyl-2-deoxycytidine
-
GC46079
5-Tricosylresorcinol
-
GC45772
6(5H)-Phenanthridinone
-
GC60532
6-(Dimethylamino)purine
-
GC30548
6-Amino-5-nitropyridin-2-one
-
GC60031
6-Azathymine
-
GC50249
6-Hydroxy-DL-DOPA
Allosteric inhibitor of RAD52; also APE1 inhibitor
-
GC32975
6-Mercaptopurine hydrate
-
GC35180
6-Methyl-5-azacytidine