Metabolism
- Sterol Biosynthesis(26)
- PPAR(216)
- 5-alpha Reductase(9)
- 5-Lipoxygenase(11)
- Adenosine Deaminase(8)
- Aminopeptidase(10)
- C14ɑ demethylase(2)
- Carbonic Anhydrase(63)
- CETP(13)
- Cholesterol absorption(1)
- CPT1(3)
- CYP3A/CYP450(26)
- Dehydrogenase(139)
- DHFR(11)
- DGAT(13)
- Dopamine β-hydroxylase(14)
- Enolase(11)
- FAAH(40)
- Factor Xa(49)
- Ferroptosis(200)
- Folate Analogue(3)
- Glucokinase(17)
- HLE(1)
- HMG-CoA Reductase(39)
- HSP(77)
- IDO(52)
- KRAS-PDEδ(4)
- MAO(9)
- Metabolic Enzymes(0)
- Neuronal Metabolism(8)
- Oxidative Phosphorylation(17)
- P450(146)
- PDE(254)
- Phospholipase(117)
- Procollagen C Proteinase(2)
- Saccharometabolism(1)
- SCD(19)
- SGLT(31)
- TPH(6)
- Transferase(183)
- Energy Metabolism(0)
- Inorganic Ions(0)
- ALP(1)
- Carbohydrates(18)
- Uric Acid(0)
- Muscle Metabolism(0)
- MDA(0)
- MPO(0)
- Transaminase(20)
- Glutathione Reductase(0)
- Thioredoxin Reductase(0)
- Catalase(8)
- monooxygenase(1)
- PKM2(1)
- aldehyde dehydrogenase(1)
- Squalene synthase(1)
- Hydrolase(47)
- ornithine decarboxylase(1)
- Amino acid metabolism(3)
- phosphatases(98)
- Pyruvate kinase(9)
- Others(4)
- MGL(1)
- Galactosidase(6)
- 12-Lipoxygenase(1)
- Fatty Acid Synthase (FASN)(9)
- Dihydroorotate Dehydrogenase(12)
- Bile Acids & Microbiome(94)
- Bone Growth & Remodeling(35)
- Carbohydrate Metabolism(126)
- Cofactors & Vitamins(64)
- Dyslipidemias(73)
- Inborn Errors of Metabolism(80)
- Metabolic Syndrome(16)
- Necroptosis(10)
- Necrosis(15)
- Nutrient Sensing(12)
- Phosphodiesterase(27)
- Reproductive Biology(126)
- Thermogenesis(6)
- Prolyl Hydroxylation Enzymes(1)
- Biliary System(4)
- Metabolic Disease(4)
- Fat Mass and Obesity-associated Protein (FTO)(2)
- SHIP(1)
Products for Metabolism
- Cat.No. Product Name Information
- GC46387 1,3,7-Trimethyluric Acid-d9 An internal standard for the quantification of 1,3,7-trimethyluric acid
- GC41846 1,3-Dioctanoyl-2-Oleoyl-rac-glycerol 1,3-Dioctanoyl-2-oleoyl-rac-glycerol is a triacylglycerol that contains octanoic acid at the sn-1 and sn-3 positions and oleic acid at the sn-2 position.
- GC41849 1,3-Dipalmitoleoyl-rac-glycerol 1,3-Dipalmitoleoyl-rac-glycerol is a diacylglycerol with palmitoleic acid at the sn-1 and sn-3 positions.
- GC40167 1,3-Dipalmitoyl-2-Docosahexaenoyl-rac-glycerol 1,3-Dipalmitoyl-2-docosahexaenoyl-rac-glycerol is a triacylglycerol that contains palmitic acid at the sn-1 and sn-3 positions and docosahexaenoic acid at the sn-2 position.
- GC41850 1,3-Dipalmitoyl-2-Eicosapentaenoyl-rac-glycerol 1,3-Dipalmitoyl-2-eicosapentaenoyl-rac-glycerol is a triacylglycerol that contains palmitic acid at the sn-1 and sn-3 positions and eicosapentaenoic acid at the sn-2 position.
- GC19528 1,4-Benzoquinone A toxic metabolite of benzene
-
GC41858
1,4-dideoxy-1,4-imino-D-Arabinitol (hydrochloride)
1,4-dideoxy-1,4-imino-D-Arabinitol (DAB) is an inhibitor of glycogen phosphorylase, a key enzyme in glycogenolysis.
- GC40741 1,6-Anhydro-D-galactose 1,6-Anhydro-D-galactose is a carbohydrate found in liquid smoke flavorings that is used as a tracer of the contribution of biomass burning to total atmospheric particulate matter.
- GC40328 1,7-Dimethyluric Acid 1,7-Dimethyluric acid is a metabolite of caffeine produced by the action of xanthine oxidase on paraxanthine.
- GC42051 1-β-D-Glucosylsphingosine (d18:1) 1-β-D-Glucosylsphingosine is a glucosylsphingosine, which are deacetylated lysolipid derivatives of glucocerebrosides.
- GC49294 1-(4-Chlorobenzhydryl)piperazine An inactive metabolite of meclizine and chlorcyclizine
- GC46477 1-Amino-1-deoxy-D-fructose (hydrochloride) An amino monosaccharide
- GC39221 1-Cyclohexyl-3-dodecyl urea 1-Cyclohexyl-3-dodecyl urea (CDU; N-Cyclohexyl-N-dodecyl urea; NCND) is a highly selective soluble epoxide hydrolase (sEH) inhibitor.
- GC17913 1-Deazaadenosine adenosine deaminase inhibitor
- GC10430 1-Deoxygalactonojirimycin (hydrochloride) 1-Deoxygalactonojirimycin (hydrochloride) (GR181413A) is a potent and competitive inhibitor of α-galactosidase A (α-Gal A) with an IC50 of 0.04 μM for human α-Gal A.
- GC18609 1-Deoxysphinganine (m18:0) 1-Deoxysphinganine (m18:0) (ES-285) is an antiproliferative (antitumoral) compound of marine origin. 1-Deoxysphinganine (m18:0) inhibits the growth of the prostate PC-3 and LNCaP cells through intracellular ceramide accumulation and PKCζ activation.
- GC33073 1-Ethynylnaphthalene 1-Ethynylnaphthalene is a selective inhibitor of cytochrome P450 1B1.
- GC35065 1-Linoleoyl Glycerol 1-Linoleoyl Glycerol is a fatty acid glycerol.
- GC35068 1-Monomyristin A monoacylglycerol
- GC33457 1-Naphthaleneacetic acid (1-Naphthylacetic acid) 1-Naphthaleneacetic acid (1-Naphthylacetic acid) (1-Naphthylacetic acid), a synthetic auxin, can promote plant growth.
- GC13379 1-Naphthyl 3,5-dinitrobenzoate dual 5-lipoxygenase and microsomal prostaglandin E synthase-1 inhibitor
- GC40910 1-Oleoyl-2-hydroxy-sn-glycero-3-PE 1-Oleoyl-2-hydroxy-sn-glycero-3-PE is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine.
- GC42029 1-Palmitoyl-2-linoleoyl PE Phosphatidylethanolamines are important components of cell membranes and biochemical pathways of fatty acid synthesis.
- GC49366 1-Salicylate Glucuronide A metabolite of salicylic acid and aspirin
- GC42039 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position.
- GC42040 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position.
- GC49730 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE-d11 An internal standard for the quantification of 1-stearoyl-2-15(S)-HETE-sn-glycero-3-PE
- GC42041 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position.
- GC42042 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position.
- GC42049 1-thio-β-D-Glucose (sodium salt) 1-thio-β-D-Glucose is an analog of β-D-glucose in which sulfur replaces the hydroxyl group at the one position.
- GC48782 10,13-epoxy-11-methyl-Octadecadienoic Acid A furan fatty acid
- GC49872 10-Formyltetrahydrofolate (sodium salt) (technical grade) 10-Formyltetrahydrofolate (sodium salt) (technical grade) is a form of tetrahydrofolic acid that acts as a donor of formyl groups in anabolism.
- GC49118 10-hydroxy Warfarin A metabolite of (R)-warfarin
- GC41867 10-Nitrolinoleate 10-Nitrolinoleate is a potent peroxisome proliferator-activated receptor γ (PPARγ) agonist.
- GC41868 10-Nitrooleate 10-Nitrooleate (CXA-10), a nitro fatty acid, has potential effects in disease states in which oxidative stress, inflammation, fibrosis, and/or direct tissue toxicity play significant roles.
- GC52026 10-oxo-12(Z),15(Z)-Octadecadienoic Acid An oxylipin gut microbiota metabolite
- GC52071 10-oxo-12(Z)-Octadecenoic Acid A metabolite of linoleic acid and an activator of TRPV1
- GC52428 10-oxo-12(Z)-Octadecenoic Acid-d5 An internal standard for the quantification of 10-oxo-12(Z)-octadecenoic acid
- GC40319 10-PAHSA 10-PAHSA is a newly identified endogenous lipid that belongs to a collection of branched fatty acid esters of hydroxy fatty acids (FAHFAs).
- GC11055 10-Pyrene-PC A substrate for some PLA2s
- GC41410 11β-Prostaglandin E2 11β-Prostaglandin E2 (11β-Dinoprostone), a Prostanoid derivative, inhibits [3H]PGE2 binding to hypothalamic membranes in the rat with a Ki of 53.3 nM.
- GC10821 11-keto-β-Boswellic Acid 11-Keto-beta-boswellic acid (11-Keto-β-boswellic acid) is a pentacyclic triterpenic acid of the oleogum resin from the bark of the Boswellia serrate tree, popularly known as Indian Frankincense. 11-Keto-beta-boswellic acid has the anti-inflammatory activity is primarily due to inhibit 5-lipoxygenase (5-LOX) and subsequent leukotriene and nuclear factor-kappa B (NF-κB) activation and tumor necrosis factor alpha generation production.
- GC63796 116-9e 116-9e (MAL2-11B) is a Hsp70 co-chaperone DNAJA1 inhibitor.
- GC64008 12-O-Methylcarnosic acid 12-O-Methylcarnosic acid (12-Methoxycarnosic acid), a diterpene carnosic acid isolated from the acetone extract of Salvia microphylla, is an active constituent of 5α-reductase inhibition with an IC50 value of 61.7 μM.
-
GC41434
13,14-dihydro Prostaglandin F2α
13,14-dihydro Prostaglandin F2α (13,14-dihydro PGF2α) is the analog of PGF2α which has no unsaturation in the lower side chain.
- GC41436 13,14-dihydro-15-keto Prostaglandin F1α 13,14-dihydro-15-keto Prostaglandin F1α (13,14-dihydro-15-keto PGF1α) is a metabolite of PGF1α that has been reported in the rat stomach.
- GC46435 13-cis-Retinoic Acid-d5 An internal standard for the quantification of 13-cis retinoic acid
- GC41907 13C C16 Sphingomyelin (d18:1/16:0) 13C C16 Sphingomyelin is an isotopically enriched form of C16 sphingomyelin with carbon-13 occurring on the fatty acid portion.
- GC41917 14-methyl Palmitic Acid 14-methyl Palmitic acid is a methylated fatty acid that has been found in bacteria, bovine milk fat, Aegean jellyfish (A.
- GC41166 15(S)-15-methyl Prostaglandin D2 15(S)-15-methyl Prostaglandin D2 (15(S)-15-methyl PGD2) is a metabolically stable synthetic analog of PGD2.
- GC41167 15(S)-15-methyl Prostaglandin E2 15(S)-15-methyl PGE2 is a potent, metabolically stable analog of PGE2.
- GC41924 15(S)-15-methyl Prostaglandin F2α isopropyl ester 15(S)-15-methyl Prostaglandin F2α (15(S)-15-methyl PGF2α) has been shown to have potent uterine stimulant and abortifacient properties when administered intramuscularly to induce labor.
- GC18372 15(S)-15-methyl Prostaglandin F2α methyl ester 15(S)-15-methyl PGF2α methyl ester is a derivative of 15(S)-15-methyl PGF2α with increased membrane permeability.
- GC13960 15-deoxy-Δ-12,14-Prostaglandin J2 15-deoxy-Δ-12,14-Prostaglandin J2 (15d-PGJ2) is a cyclopentenone prostaglandin and a metabolite of PGD2.
- GC46447 15-deoxy-δ12,14-Prostaglandin J2-d4 An internal standard for the quantification of 15deoxyΔ12,14prostaglandin J2
- GC40582 15-keto Prostaglandin F1α 15-keto PGF1α is the initial metabolite of PGF1α via 15-hydroxy PGDH.
-
GC41418
15-keto Prostaglandin F2α
15-keto Prostaglandin F2α (15-keto PGF2α) is the first metabolite of PGF2α.
- GC41937 15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide), an F-series PG analog which has been approved for use as an ocular hypotensive drug.
-
GC41939
15-methyl Palmitic Acid
15-methyl Palmitic acid is a methylated fatty acid that has been found in bacteria, bovine milk fat, one-humped camel (C.
- GC18774 16,16-dimethyl Prostaglandin F2α 16,16-dimethyl PGF2α is a metabolically stable analog of PGF2α.
- GC49848 16-Ketoestradiol An active metabolite of estrone
- GC41946 16-phenoxy tetranor Prostaglandin F2α 16-phenoxy PGF2α is a metabolically stable analog of PGF2α.
- GC40961 16-phenoxy tetranor Prostaglandin F2α methyl ester Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor.
- GC41321 17α,20β-Dihydroxy-4-pregnen-3-one An endogenous, maturation-inducing steroid
- GC46470 17β-Estradiol-d2 17β-Estradiol-d2 (β-17β-Estradiol-d2) is the deuterium labeled Estradiol.
- GC41300 17β-hydroxy Exemestane 17β-hydroxy Exemestane is the primary active metabolite of exemestane.
- GC41955 17-DMAG 17-DMAG (17-DMAG) is a potent inhibitor of Hsp90, binding to Hsp90 with an EC50 of 62 ± 29 nM.
- GC13044 17-DMAG (Alvespimycin) HCl 17-DMAG (Alvespimycin) HCl (17-DMAG hydrochloride; KOS-1022; BMS 826476) is a potent inhibitor of Hsp90, binding to Hsp90 with EC50 of 62±29 nM.
- GC48819 17-Epiestriol A metabolite of estrone
- GC41966 17-phenyl trinor Prostaglandin E2 ethyl amide 17-phenyl trinor PGE2 ethyl amide is derived from 17-phenyl trinor PGE2, a synthetic analog of PGE2 that acts as an agonist of EP1 and EP3 receptors in mice (Ki = 14 and 3.7 nM, respectively) and EP1, EP3, and EP4 in rats (Ki = 25, 4.3, and 54 nM, respectively).
- GC40392 17-phenyl trinor Prostaglandin F2α methyl ester 17-phenyl trinor Prostaglandin F2α methyl ester is a prodrug of Bimatoprost.
- GC41976 17-trifluoromethylphenyl trinor Prostaglandin F2α ethyl amide Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity.
- GC18816 19(R)-hydroxy Prostaglandin E1 19(R)-hydroxy PGE1 is the major prostaglandin found in the semen of primates, including man.
- GC49514 2′-Deoxyuridine-d2 An internal standard for the quantification of 2’-deoxyuridine
- GC52122 2’-Deoxyadenosine-5’-diphosphate (sodium salt) A nucleotide diphosphate
- GC46508 2',2'-Difluoro-2'-deoxyuridine An active metabolite of gemcitabine
- GC46540 2'-Deoxyadenosine-5'-triphosphate (sodium salt hydrate) A purine nucleotide
- GC42151 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate) 2'-Deoxyguanosine 5'-monophosphate (dGMP) is used as a substrate of guanylate kinases to generate dGDP, which in turn is phosphorylated to dGTP, a nucleotide precursor used in DNA synthesis.
- GC46509 2,3,4,5-Tetrachlorophenol A metabolite of γ-lindane
- GC42058 2,3,4,6-Tetra-O-benzoyl-β-D-glucopyranose 2,3,4,6-Tetra-O-benzoyl-β-D-glucopyranose is a D-glucopyranose derivative that has been used in glucosylation reactions.
- GC13836 2,3-dihydrothieno-Thiadiazole Carboxylate CYP450 enzymes (CYP2E1 and CYP2B4) inhibitor
- GC48459 2,3-Indolobetulin A derivative of betulin
- GC48444 2,3-Indolobetulonic Acid An inhibitor of α-glucosidase
- GC49671 2,3-Oxidosqualene An intermediate in the biosynthesis of sterols
- GC41470 2,5-Anhydro-D-mannitol 2,5-Anhydro-D-mannitol is an antimetabolic fructose analogue that increases food intake in rats at doses of 50-800 mg/kg by inhibiting gluconeogenesis and glycogenolysis in the liver..
- GC49159 2-(1-Piperazinyl)pyrimidine An α2-AR antagonist and active metabolite of azapirones
- GC49330 2-(2-Aminoethyl)-3-(4-chlorophenyl)-3-hydroxyisoindol-1-one (hydrochloride) A metabolite of mazindol
- GC30561 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide is a compound that inhibits stress-induced ulcer and low toxicity, and can maintain the content of phospholipase A2 and prostaglandin E2 in ulcerated rats induced by water immersed restrained stress.
- GC65414 2-(Tetradecylthio)acetic acid 2-Tetradecylthio acetic acid is a pan-peroxisome proliferator activated receptor (pan-PPAR) activator.
- GC13956 2-Acetamidophenyl 5-chloro-2-nitrophenyl sulfide 2-Acetamidophenyl 5-chloro-2-nitrophenyl sulfide (compound 2) is a potent PDE7 (phosphodiesterase 7) inhibitor with IC50 value of 2.1 μM.
- GC34186 2-Aminobenzenesulfonamide (Orthanilamide) 2-Aminobenzenesulfonamide (Orthanilamide) is a carbonic anhydrase IX inhibitor.
- GC49609 2-bromo 17β-Estradiol A synthetic steroid and inhibitor of estrogen 2-hydroxylase
- GC49272 2-Chloro-4-nitrophenyl α-D-maltotrioside A colorimetric α-amylase substrate
- GC42137 2-Chloro-4-nitrophenyl-α-D-glucopyranoside Carbohydrates conjugated with 2-chloro-4-nitrophenyl (CNP) serve as chromogenic substrates in assays for enzymes that release CNP from the conjugated carbohydrate.
- GC46539 2-Chloroadenine A heterocyclic building block
- GC41528 2-deoxy-2-fluoro L-Fucose Fucose is a deoxyhexose that is present in many organisms.
- GC48943 2-deoxy-2-fluoro-D-Glucose A glucose derivative with anticancer activity
- GC40675 2-deoxy-Artemisinin 2-deoxy-Artemisinin is an inactive metabolite of the antimalarial agent artemisinin.
- GC49223 2-deoxy-D-Glucose-13C6 An internal standard for the quantification of 2-deoxy-D-glucose
-
GC19427
2-deoxy-D-Glucose-6-phosphate (sodium salt)
A synthetic analog of glucose used in cell metabolism and cancer research