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Home >> Signaling Pathways >> Metabolism

Metabolism

Products for  Metabolism

  1. Cat.No. Product Name Information
  2. GC31103 Arimoclomol maleate (BRX-220) Arimoclomol maleate (BRX-220) (BRX-220) is a co-inducer of heat shock proteins (HSP). Arimoclomol maleate (BRX-220) Chemical Structure
  3. GC35390 Aristolochic acid C An alkaloid with anticancer activity Aristolochic acid C Chemical Structure
  4. GC42855 ARN19874 ARN19874 is an inhibitor of N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD; IC50 = 33.7 μM). ARN19874 Chemical Structure
  5. GC35398 Arteannuin B Arteannuin B co-occurs with artemisinin, which is the potent antimalarial principle of the Chinese medicinal herb Artemisia annua (Asteraceae). Arteannuin B Chemical Structure
  6. GC35399 Artefenomel An antimalarial agent Artefenomel Chemical Structure
  7. GN10647 Artemisinine Artemisinine Chemical Structure
  8. GC10889 Artesunate Derivative of the natural product artemisinin Artesunate Chemical Structure
  9. GC13516 AS 1949490 Selective SHIP2 inhibitor AS 1949490 Chemical Structure
  10. GC50726 ASB 14780 ASB 14780 is a 4-phenoxy derivative, the cytosolic Phospholipase A2α (cPLA2α) inhibitor, with an IC50 value of 20 nM. ASB 14780 Chemical Structure
  11. GC31350 Astaxanthin Astaxanthin, the red dietary carotenoid, is an orally effective and potent antioxidant. Astaxanthin Chemical Structure
  12. GC65912 Asundexian Asundexian (BAY 2433334) is an orally active coagulation factor Xia (FXIa) inhibitor. Asundexian binds directly, potently, and reversibly to the active site of FXIa and thereby inhibits its activity. Asundexian inhibits human FXIa in buffer with an IC50 of 1 nM. Asundexian Chemical Structure
  13. GC13414 AT13387 AT13387 (AT13387) is a long-acting second-generation Hsp90 inhibitor with a Kd of 0.71 nM. AT13387 Chemical Structure
  14. GC12945 Atazanavir An inhibitor of HIV-1 protease Atazanavir Chemical Structure
  15. GC10240 Atazanavir sulfate (BMS-232632-05) An inhibitor of HIV-1 protease Atazanavir sulfate (BMS-232632-05) Chemical Structure
  16. GC35419 Atorvastatin Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids. Atorvastatin Chemical Structure
  17. GC46889 Atorvastatin (calcium salt hydrate) An HMG-CoA reductase inhibitor Atorvastatin (calcium salt hydrate) Chemical Structure
  18. GC14038 Atorvastatin Calcium An HMG-CoA reductase inhibitor Atorvastatin Calcium Chemical Structure
  19. GC42868 Atorvastatin lactone Atorvastatin lactone is a prodrug form of atorvastatin, an HMG-CoA reductase inhibitor used to lower blood cholesterol levels. Atorvastatin lactone Chemical Structure
  20. GC49421 Atorvastatin lactone-d5 An internal standard for the quantification of atorvastatin lactone Atorvastatin lactone-d5 Chemical Structure
  21. GC65088 Atovaquone-d5 Atovaquone-d5 Chemical Structure
  22. GC46892 ATRA-BA Hybrid A prodrug form of all-trans retinoic acid and butyric acid ATRA-BA Hybrid Chemical Structure
  23. GC42870 Atrazine Mercapturate Atrazine mercapturate is a major, glutathione-derived metabolite of atrazine, an herbicide that is effective in controlling a broad range of weeds. Atrazine Mercapturate Chemical Structure
  24. GC64973 ATX inhibitor 1 ATX inhibitor 1 is a potent ATX (IC50=1.23 nM, FS-3 and 2.18 nM, bis-pNPP) inhibitor. ATX inhibitor 1 Chemical Structure
  25. GC62403 ATX inhibitor 5 ATX inhibitor 5 is a potent and orally active autotaxin (ATX) inhibitor, with an IC50 of 15.3 nM. ATX inhibitor 5 Chemical Structure
  26. GC10381 AUDA Potent epoxide hydrolase inhibitor/PPARα activator AUDA Chemical Structure
  27. GC46896 Australine (hydrochloride) A pyrrolizidine alkaloid Australine (hydrochloride) Chemical Structure
  28. GC46897 AUTEN-99 AUTEN-99 (hydrobromide) is a novel inhibitor of the myotubularin phosphatase Jumpy (also called MTMR14). AUTEN-99 Chemical Structure
  29. GC30390 Autotaxin modulator 1 Autotaxin modulator 1 is an autotaxin (ATX) enzyme inhibitor, extracted from patent WO 2014018881 A1, Compound Example 12b. Autotaxin modulator 1 Chemical Structure
  30. GC38890 Autotaxin-IN-3 Autotaxin-IN-3 is a Autotaxin(ATX) inhibitor with an IC50 of 2.4 nM, compound 33, sourced from patent WO2018212534A1. Autotaxin-IN-3 Chemical Structure
  31. GC16856 Avanafil A potent and selective PDE5 inhibitor Avanafil Chemical Structure
  32. GC42878 Avanafil metabolite M16 Avanafil metabolite M16 is a major inactive metabolite of the phosphodiesterase 5 (PDE5) inhibitor avanafil. Avanafil metabolite M16 Chemical Structure
  33. GC42879 Avanafil metabolite M4 Avanafil metabolite M4 is a major active metabolite of the phosphodiesterase 5 (PDE5) inhibitor avanafil. Avanafil metabolite M4 Chemical Structure
  34. GC10999 Avasimibe An ACAT inhibitor Avasimibe Chemical Structure
  35. GC31452 AVE-8134 AVE-8134 is a potent PPARα agonist, with EC50 values of 100 and 3000 nM for human and rodent PPARα receptor, respectively. AVE-8134 Chemical Structure
  36. GC42885 AX 048 The group IVA phospholipase A2 (PLA2), known as calcium-dependent cytosolic PLA2 (cPLA2), selectively releases arachidonic acid from membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins and leukotrienes. AX 048 Chemical Structure
  37. GC42887 Axitinib Sulfoxide Axitinib sulfoxide is a major inactive metabolite of the tyrosine kinase inhibitor axitinib. Axitinib Sulfoxide Chemical Structure
  38. GC60063 Ayanin Ayanin is a bioflavonoid isolated from Croton schiedeanus Schlecht. Ayanin Chemical Structure
  39. GC49784 AZD 2716 An sPLA2 inhibitor AZD 2716 Chemical Structure
  40. GC16257 AZD 3988 diacylglycerol acyltransferase (DGAT-1) inhibitor AZD 3988 Chemical Structure
  41. GC64099 AZD-9574 AZD-9574 is a potent and brain penetrant PARP1 inhibitor and shows >8000-fold selectivity for PARP1 compared to PARP2/3/5a/6. AZD-9574 Chemical Structure
  42. GC11475 AZD7687 AZD7687 Chemical Structure
  43. GC42890 Azelaoyl PAF Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which promote the differentiation of monocytes via the nuclear receptor PPARγ. Azelaoyl PAF Chemical Structure
  44. GC13829 BADGE

    PPARγ antagonist

     BADGE Chemical Structure
  45. GN10158 Baicalein Baicalein Chemical Structure
  46. GC12894 Balaglitazone A partial agonist of PPARγ Balaglitazone Chemical Structure
  47. GC19343 Balipodect TAK-063 is a highly potent, selective and orally active PDE10A inhibitor with IC50 of 0.30 nM; >15000-fold selectivity over other PDEs. Balipodect Chemical Structure
  48. GC52409 BAM-22P (8-22) (human, mouse, rat, bovine) (trifluoroacetate salt) A neuropeptide and MRGPRX1 agonist BAM-22P (8-22) (human, mouse, rat, bovine) (trifluoroacetate salt) Chemical Structure
  49. GC67211 BAPTA tetrapotassium BAPTA tetrapotassium is a selective chelator for calcium. BAPTA, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA tetrapotassium is widely used as an intracellular buffer for investigating the effects of Ca2+ release from intracellular stores or influx via Ca2+-permeable channels in the plasma membrane. BAPTA tetrapotassium can also inhibit phospholipase C activity independently of their role as Ca2+ chelators. BAPTA tetrapotassium Chemical Structure
  50. GC18313 BAR501 Impurity BAR501 impurity is an impurity found in the preparation of BAR501 that acts as an agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1). BAR501 Impurity Chemical Structure
  51. GC11572 Bardoxolone methyl A synthetic triterpenoid with potent anticancer and antidiabetic activity Bardoxolone methyl Chemical Structure
  52. GC10345 Bay 11-7085

    NK-κB activation inhibitor

     Bay 11-7085 Chemical Structure
  53. GC64703 BAY 2666605 BAY 2666605 is an orally active PDE3A and PDE3B inhibitor with IC50s of 87 nM and 50 nM, respectively. BAY 2666605 is a PDE3A-SLFN12 complex inducer (WO2019025562A1; example 135). BAY 2666605 Chemical Structure
  54. GC19512 Bay 60-7550

    Bay 60-7550 is a potent and selective PDE2 inhibitor with a Ki of 3.8 nM

     Bay 60-7550 Chemical Structure
  55. GC30923 BAY 73-6691 ((R)-BAY 73-6691) BAY 73-6691 ((R)-BAY 73-6691) ((R)-BAY 73-6691 ((R)-BAY 73-6691)) is a potent, brain penetrant, and selective PDE9A inhibitor. BAY 73-6691 ((R)-BAY 73-6691) Chemical Structure
  56. GC30915 BAY 73-6691 racemate BAY 73-6691 racemate is a phosphodiesterase 9 inhibitor extracted from patent WO 2017070293 A1. BAY 73-6691 racemate Chemical Structure
  57. GC12698 BAY 87-2243 A HIF-1 inhibitor,potent and selective BAY 87-2243 Chemical Structure
  58. GC19000 BAY-588 BAY-588 is a glucose transporter inhibitor and derivative of BAY-876 . BAY-588 Chemical Structure
  59. GC16048 BC 11-38 Selective PDE11 inhibitor BC 11-38 Chemical Structure
  60. GC12912 BCATc Inhibitor 2

    cytosolic BCAT (BCATc) inhibitor

     BCATc Inhibitor 2 Chemical Structure
  61. GC38646 BCI BCI, as a selective dual-specificity phosphatase 6 (DUSP6) inhibitor, can inhibit tumor growth and macrophage inflammation. BCI Chemical Structure
  62. GC39160 BCI-215 BCI-215 is a potent and tumor cell-selective dual specificity MAPK phosphatase (DUSP-MKP) inhibitor. BCI-215 has cytotoxicity for tumor cells but not normal cells. BCI-215 Chemical Structure
  63. GC52317 BCP-T.A. A ferroptosis inducer BCP-T.A. Chemical Structure
  64. GC49044 Benastatin C A bacterial metabolite with diverse biological activities Benastatin C Chemical Structure
  65. GC42913 Benazeprilat

    Benazeprilat is an inhibitor of angiotensin-converting enzyme (ACE; IC50 = 0.28 nM in plasma from dog) and the active metabolite of the prodrug benazepril.

     Benazeprilat Chemical Structure
  66. GC49403 Benzarone An active metabolite of benzbromarone Benzarone Chemical Structure
  67. GC17003 Benzenesulfonamide carbonic anhydrase inhibitor Benzenesulfonamide Chemical Structure
  68. GC64734 Benzenesulphonamide Benzenesulphonamide (compound 1) is a potent carbonic anhydrase inhibitor. Benzenesulphonamide shows CA II inhibitory activity. Benzenesulphonamide Chemical Structure
  69. GC62864 Benzolamide Benzolamide (CL11366) is a potent carbonic anhydrase (CA) inhibitor, with Kis of 15 nM, 9 nM, 94 nM and 78 nM for hCA I, hCA II, EcoCAγ and VchCAγ, respectively. Benzolamide Chemical Structure
  70. GC49318 Benzovindiflupyr A fungicide Benzovindiflupyr Chemical Structure
  71. GC42920 Benzoyl Coenzyme A (sodium salt) Benzoyl coenzyme A (benzoyl-CoA) is an intermediate in the microbial metabolism of aromatic compounds. Benzoyl Coenzyme A (sodium salt) Chemical Structure
  72. GC32634 Benzthiazide Benzthiazide is a long-acting diuretic and a hypertension agent. Benzthiazide Chemical Structure
  73. GC49387 Berberine-d6 (chloride) An internal standard for the quantification of berberine Berberine-d6 (chloride) Chemical Structure
  74. GC34132 Bergamottin (5-Geranoxypsoralen) Bergamottin (5-Geranoxypsoralen) is a potent and competitive CYP1A1 inhibitor with a Ki of 10.703 nM. Bergamottin (5-Geranoxypsoralen) Chemical Structure
  75. GC33909 Bergaptol (5-Hydroxypsoralen) Bergaptol (5-Hydroxypsoralen) is a hydroxylated psoralen that acts as a potent inhibitors of debenzylation activity of CYP3A4 enzyme with an IC50 value of 24.92 uM. Bergaptol (5-Hydroxypsoralen) Chemical Structure
  76. GC15577 Bestatin hydrochloride Inhibitor of aminopeptidase N (APN)/CD13 and aminopeptidase B. Bestatin hydrochloride Chemical Structure
  77. GC35499 Bestatin trifluoroacetate Bestatin trifluoroacetate is an inhibitor of CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase, used for cancer research. Bestatin trifluoroacetate Chemical Structure
  78. GC42926 Betaine Aldehyde (chloride) Betaine aldehyde is the physiological intermediate in the oxidation of choline to betaine. Betaine Aldehyde (chloride) Chemical Structure
  79. GC52329 Betamethasone-d5 An internal standard for the quantification of betamethasone Betamethasone-d5 Chemical Structure
  80. GC17799 Betrixaban Factor Xa inhibitor Betrixaban Chemical Structure
  81. GC61748 Betrixaban D6 Betrixaban D6 is a deuterium labeled Betrixaban. Betrixaban D6 Chemical Structure
  82. GC25137 Betrixaban maleate Betrixaban maleate is the maleate salt form of Betrixaban, which is a Factor Xa inhibitor that decreases prothrombinase activity and thrombin generation. Betrixaban maleate Chemical Structure
  83. GC19065 Bexagliflozin Bexagliflozin is a potent and selective SGLT2 inhibitor with IC50 value of 5.6 uM /2 nM in SGLT1 /SGLT2 respectively. Bexagliflozin Chemical Structure
  84. GC14543 Bezafibrate Lipid-lowering agent Bezafibrate Chemical Structure
  85. GC45726 Bezafibrate-d4 An internal standard for the quantification of bezafibrate Bezafibrate-d4 Chemical Structure
  86. GC42928 BHT BHT is an antioxidant widely used in foods and in food-related products. BHT is a Ferroptosis inhibitor. BHT Chemical Structure
  87. GC68758 BI 1015550

    BI 1015550 is an orally active PDE4B inhibitor with an IC50 value of 7.2 nM. It has good safety and potential applications in inflammation, allergic diseases, pulmonary fibrosis, and chronic obstructive pulmonary disease (COPD).

     BI 1015550 Chemical Structure
  88. GC65345 BI 653048 BI 653048 is a selective and orally active nonsteroidal?glucocorticoid (GC)?agonist with an IC50 value of 55 nM. BI 653048 Chemical Structure
  89. GC32419 BI 689648 BI 689648 is a novel, highly selective aldosterone synthase inhibitor which can inhibit CYP11B1 and CYP11B2 with IC50s of 310 and 2.1 nM, respectively. BI 689648 Chemical Structure
  90. GC60073 BI-1935 BI-1935 is a potent soluble epoxide hydrolase (sEH) inhibitor. BI-1935 Chemical Structure
  91. GC60074 BI-2545 BI-2545 is a potent autotaxin (ATX) inhibitor that significantly reduces LPA, with IC50s of 2.2 nM and 3.4 nM for human ATX and rat ATX, respectively. BI-2545 Chemical Structure
  92. GC19068 BI-409306 BI-409306 (BI-409306) is a potent and selective PDE9A inhibitor, with an IC50 of 52 nM, and shows weak activity against other PDEs, such as PDE1A (IC50, 1.4 μM), PDE1C (IC50, 1.0 μM), PDE2A, PDE3A, PDE4B, PDE5A, PDE6AB, PDE7A, and PDE10A (IC50 all > 10 μM); BI-409306 can be used in the research of memory enhancement in CNS disorders. BI-409306 Chemical Structure
  93. GC18174 BIA 10-2474 BIA 10-2474 is an inhibitor of fatty acid amide hydrolase (FAAH; IC50 = 4.9 nM in HEK293T cells expressing the human recombinant enzyme). BIA 10-2474 Chemical Structure
  94. GC42931 Bilirubin Conjugate (sodium salt) Bilirubin Conjugate (sodium salt) is a ditaurate derivative of Bilirubin. Bilirubin Conjugate (sodium salt) Chemical Structure
  95. GC35518 Bilobetin A biflavonoid with diverse biological activities Bilobetin Chemical Structure
  96. GC32620 Bimoclomol Bimoclomol is a heat shock protein (HSP) coinducer, used for treatment of cardiovascular diseases. Bimoclomol Chemical Structure
  97. GN10618 Biochanin A Biochanin A Chemical Structure
  98. GC49200 Biotin (R)-Sulfoxide A metabolite of biotin Biotin (R)-Sulfoxide Chemical Structure
  99. GC49170 Biotin (S)-sulfoxide An inactive metabolite of biotin Biotin (S)-sulfoxide Chemical Structure
  100. GC42951 BMP-22 BMP-22 is an inhibitor of autotaxin (IC50 = 170 nM). BMP-22 Chemical Structure
  101. GC52376 BMP2-derived Peptide (trifluoroacetate salt) A synthetic peptide BMP2-derived Peptide (trifluoroacetate salt) Chemical Structure

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