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Metabolism

Products for  Metabolism

  1. Cat.No. Product Name Information
  2. GC33337 CDC801 CDC801 is a potent and orally active phosphodiesterase 4 (PDE4) and tumor necrosis factor-α (TNF-α) inhibitor with IC50 of 1.1 μM and 2.5 μM, respectively. CDC801  Chemical Structure
  3. GC31464 CDD3505 CDD3505 is used for elevating high density lipoprotein cholesterol (HDL) by inducing hepatic cytochrome P450IIIA (CYP3A) activity. CDD3505  Chemical Structure
  4. GC31460 CDD3506 CDD3506 is used for elevating high density lipoprotein cholesterol (HDL) by inducing hepatic cytochrome P450IIIA (CYP3A) activity. CDD3506  Chemical Structure
  5. GC32723 CDDO-Im (RTA-403) CDDO-Im (RTA-403) (RTA-403) is an activator of Nrf2 and PPAR, with Kis of 232 and 344 nM for PPARα and PPARγ. CDDO-Im (RTA-403)  Chemical Structure
  6. GC16632 CDP 840 hydrochloride CDP 840 hydrochloride (GR259653X) is a potent, selective and orally active phosphodiesterase IV (PDE IV) inhibitor. CDP 840 hydrochloride  Chemical Structure
  7. GC32991 Cecropin B Cecropin B has high level of antimicrobial activity and is considered as a valuable peptide antibiotic. Cecropin B  Chemical Structure
  8. GC38681 Cedrol A sesquiterpene alcohol Cedrol  Chemical Structure
  9. GC61805 Cefminox sodium Cefminox sodium (MT-141) is a semisynthetic cephamycin, which exhibits a broad spectrum of antibacterial activity. Cefminox sodium  Chemical Structure
  10. GC49152 Celecoxib Carboxylic Acid An inactive metabolite of celecoxib Celecoxib Carboxylic Acid  Chemical Structure
  11. GC43225 Celecoxib Carboxylic Acid Acyl-β-D-Glucuronide Celecoxib carboxylic acid acyl-β-D-glucuronide is a phase II metabolite of celecoxib. Celecoxib Carboxylic Acid Acyl-β-D-Glucuronide  Chemical Structure
  12. GC43226 Cellobiosan Cellobiosan is an anhydro sugar formed during biofuel production from the fast pyrolysis of wood. Cellobiosan  Chemical Structure
  13. GC43231 Cerivastatin (sodium salt) Cerivastatin (sodium salt) is a synthetic lipid-lowering agent and a highly potent, well-tolerated and orally active HMG-CoA reductase inhibitor, with a Ki of 1.3 nM/L. Cerivastatin (sodium salt)  Chemical Structure
  14. GC16301 Cetaben unique,PPARα-independent peroxisome proliferator Cetaben  Chemical Structure
  15. GC35657 CETP-IN-3 CETP-IN-3 (Compound 13) is an small molecule inhibitor of the plasma glycoprotein cholesterol ester transfer protein (CETP), elevating HDL-C through inhibition of CETP. CETP-IN-3  Chemical Structure
  16. GC13611 CGP 3466B maleate CGP 3466B maleate, an orally bioavailable GAPDH nitrosylation inhibitor, abrogates Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice. CGP 3466B maleate  Chemical Structure
  17. GC32422 CGP-53153 CGP-53153 is a steroidal inhibitor of 5 alpha reductase with IC50s of 36 and 262 nM in rat and human prostatic tissue, respectively. CGP-53153  Chemical Structure
  18. GC17822 CH5138303 Hsp90 inhibitor, orally available CH5138303  Chemical Structure
  19. GC52081 Chamazulene

    Chamazulene is a terpene that has been found in chamomile (M. recutita) flowers and has anti-inflammatory and antioxidant activities.

    Chamazulene  Chemical Structure
  20. GC48424 Chenodeoxycholic Acid 24-Acyl-β-D-Glucuronide A metabolite of CDCA Chenodeoxycholic Acid 24-Acyl-β-D-Glucuronide  Chemical Structure
  21. GC47076 Chenodeoxycholic Acid-d4 A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications Chenodeoxycholic Acid-d4  Chemical Structure
  22. GC31552 Chiglitazar Chiglitazar (Carfloglitazar) is a PPARα/γ dual agonist, with EC50s of 1.2, 0.08, 1.7 μM for PPARα, PPARγ and PPARδ, respectively. Chiglitazar  Chemical Structure
  23. GC62336 CHIKV-IN-2 CHIKV-IN-2 is a potent inhibitor against Chikungunya virus (CHIKV), with excellent cellular antiviral activity (EC90=270 nM) and improved liver microsomal stability. CHIKV-IN-2  Chemical Structure
  24. GC43238 Chitobiose Octaacetate Chitobiose is a dimer of β-1,4 linked glucosamine units derived from chitin, which, in turn, is a long chain polymer of N-acetylglucosamine that is a primary component of fungal cell walls and arthropod exoskeletons. Chitobiose Octaacetate  Chemical Structure
  25. GC45792 Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) An inducer of ferroptosis Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III)  Chemical Structure
  26. GC47080 Chlorophenol Red β-D-Galactopyranoside Chlorophenol Red β-D-Galactopyranoside is a long-wavelength dye, which has been widely used for colorimetric assays. Chlorophenol Red β-D-Galactopyranoside  Chemical Structure
  27. GC47084 Chlorpyrifos-methyl An organophosphate insecticide Chlorpyrifos-methyl  Chemical Structure
  28. GC16751 Chlorzoxazone Muscle-relaxing drug Chlorzoxazone  Chemical Structure
  29. GC43248 Chlorzoxazone N-Glucuronide Chlorzoxazone N-glucuronide is a phase II metabolite of the skeletal muscle relaxant chlorzoxazone. Chlorzoxazone N-Glucuronide  Chemical Structure
  30. GC46118 Chlothianidin A neonicotinoid insecticide Chlothianidin  Chemical Structure
  31. GC40203 Cholesterol-d6

    Cholesterol-d6 is intended for use as an internal standard for the quantification of cholesterol by GC- or LC-MS.

    Cholesterol-d6  Chemical Structure
  32. GC47085 Cholesterol-d7 An internal standard for the quantification of cholesterol Cholesterol-d7  Chemical Structure
  33. GC40041 Cholesteryl Lignocerate Cholesteryl lignocerate is a cholesterol ester that has been found in human meibum. Cholesteryl Lignocerate  Chemical Structure
  34. GC43264 Cholic Acid 7-sulfate

    Cholic acid 7-sulfate is a metabolite of the primary bile acid cholic acid.

    Cholic Acid 7-sulfate  Chemical Structure
  35. GC46119 Cholic Acid anilide A synthetic bile acid Cholic Acid anilide  Chemical Structure
  36. GC47086 Cholic Acid-d4 A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications Cholic Acid-d4  Chemical Structure
  37. GC11170 Choline Fenofibrate Choline Fenofibrate  Chemical Structure
  38. GC35692 Chrysosplenetin A flavonoid with diverse biological activities Chrysosplenetin  Chemical Structure
  39. GC31786 CI-1044 (PD-189659) CI-1044 (PD-189659) is an orally active PDE4 inhibitor with IC50s of 0.29, 0.08, 0.56, 0.09 μM for PDE4A5, PDE4B2, PDE4C2 and PDE4D3, respectively. CI-1044 (PD-189659)  Chemical Structure
  40. GC10132 Ciclopirox broad-spectrum antifungal agent Ciclopirox  Chemical Structure
  41. GC11120 Ciclopirox ethanolamine Ciclopirox ethanolamine (Ciclopirox ethanolamine) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox ethanolamine  Chemical Structure
  42. GC17135 Ciglitazone PPARγ agonist Ciglitazone  Chemical Structure
  43. GC32237 CIL56 An inducer of non-apoptotic cell death; YAP1 (YES related protein 1) targeted inhibitor CIL56  Chemical Structure
  44. GC17598 Cilomilast A PDE4 inhibitor Cilomilast  Chemical Structure
  45. GC10109 Cilostamide type III phosphodiesterase (PDE3) inhibitor Cilostamide  Chemical Structure
  46. GC15890 Cilostazol A PDE3A inhibitor Cilostazol  Chemical Structure
  47. GC47088 Cilostazol-d4 An internal standard for the quantification of cilostazol Cilostazol-d4  Chemical Structure
  48. GN10678 Cinnamyl alcohol Cinnamyl alcohol  Chemical Structure
  49. GC13633 Ciprofibrate A selective PPARα agonist Ciprofibrate  Chemical Structure
  50. GC35698 Ciprofibrate D6 Ciprofibrate D6 is deuterium labeled Ciprofibrate. Ciprofibrate D6  Chemical Structure
  51. GC60710 Ciprofibrate impurity A Ciprofibrate impurity A is an impurity of Ciprofibrate. Ciprofibrate (Win35833) is a potent peroxisome proliferator, increases the phosphorylation level of the PPARalpha. Ciprofibrate impurity A  Chemical Structure
  52. GC40834 cis-Entacapone cis-Entacapone is a metabolite of the catechol-O-methyltransferase (COMT) inhibitor entacapone. cis-Entacapone  Chemical Structure
  53. GC40545 cis-Parinaric Acid

    cis-Parinaric acid is a naturally occurring polyunsaturated fatty acid containing an unusual conjugated (Z,E,E,Z) tetraene.

    cis-Parinaric Acid  Chemical Structure
  54. GC11908 Cisplatin Cisplatin is one of the best and first metal-based chemotherapeutic drugs, which is used for wide range of solid cancers such as testicular, ovarian, bladder, lung, cervical, head and neck cancer, gastric cancer and some other cancers. Cisplatin  Chemical Structure
  55. GC52351 Citrullinated α-Enolase (R8 + R14) (1-19)-biotin Peptide A biotinylated and citrullinated α-enolase peptide Citrullinated α-Enolase (R8 + R14) (1-19)-biotin Peptide  Chemical Structure
  56. GC49556 Cl-Necrostatin-1 A RIPK1 inhibitor Cl-Necrostatin-1  Chemical Structure
  57. GC10509 Cladribine Apoptosis inducer in CLL cells Cladribine  Chemical Structure
  58. GC16754 Clarithromycin A macrolide antibiotic Clarithromycin  Chemical Structure
  59. GC15810 Clinofibrate HMGCR inhibitor Clinofibrate  Chemical Structure
  60. GC17377 Clofibrate PPAR agonist Clofibrate  Chemical Structure
  61. GC49087 Clofibric Acid-d4 An internal standard for the quantification of clofibric acid Clofibric Acid-d4  Chemical Structure
  62. GC38758 Clomethiazole Chlormethiazole is an potent and orally active GABAA?agonist. Clomethiazole  Chemical Structure
  63. GC43281 Clopidogrel Carboxylic Acid (hydrochloride) Clopidogrel is an antithrombic compound whose active metabolite is a selective, irreversible antagonist of the platelet purinergic P2Y12 receptor (IC50 = 100 nM). Clopidogrel Carboxylic Acid (hydrochloride)  Chemical Structure
  64. GC14122 Clorgyline (hydrochloride) MAO-A inhibitor Clorgyline (hydrochloride)  Chemical Structure
  65. GC65426 CM-675 CM-675 is a dual phosphodiesterase 5 (PDE5) and class I histone deacetylases-selective inhibitor, with IC50 values of 114 nM and 673 nM for PDE5 and HDAC1, respectively. CM-675  Chemical Structure
  66. GC14269 Cobicistat (GS-9350) An inhibitor of CYP3A Cobicistat (GS-9350)  Chemical Structure
  67. GN10668 Coenzyme Q10 Coenzyme Q10  Chemical Structure
  68. GC43297 Coenzyme Q2 Coenzyme Q10 is a component of the electron transport chain and participates in aerobic cellular respiration, generating energy in the form of ATP. Coenzyme Q2  Chemical Structure
  69. GC34539 Col003

    Col003 is a selective and potent inhibitor of?Hsp47 and competitively binds to the collagen binding site on Hsp47 (IC50=1.8 μM).

    Col003  Chemical Structure
  70. GC49454 Complex 3 A fluorescent copper complex with anticancer activity Complex 3  Chemical Structure
  71. GC43305 Compound 48/80 (hydrochloride) Compound 48/80 (hydrochloride) (C48/80 trihydrochloride) is a mixture of condensation products of N-methyl-p-methoxyphenethylamine with formaldehyde. Compound 48/80 (hydrochloride)  Chemical Structure
  72. GN10338 Compound K Compound K  Chemical Structure
  73. GC43307 Concanamycin B Concanamycin B is a macrolide antibiotic that selectively inhibits vacuolar type H+-ATPases, also known as V-ATPases (IC50 = 5 nM). Concanamycin B  Chemical Structure
  74. GC18572 Concanavalin A

    Concanamycin A belongs to the concanamycins, a family of macrolide antibiotics isolated from Streptomyces diastatochromogenes that are highly active and selective inhibitors of the vacuolar proton-ATPase (v-[H+]ATPase).

    Concanavalin A  Chemical Structure
  75. GC39701 Convallatoxin Convallatoxin is a cardiac glycoside isolated from Adonis amurensis Regel et Radde. Convallatoxin  Chemical Structure
  76. GN10414 Coptisine Coptisine  Chemical Structure
  77. GN10577 Coptisine chloride Coptisine chloride  Chemical Structure
  78. GN10609 Coptisine Sulfate Coptisine Sulfate  Chemical Structure
  79. GC45724 Corticosterone-d8 An internal standard for the quantification of corticosterone Corticosterone-d8  Chemical Structure
  80. GC47123 Coumarin-Quinone Conjugate A fluorescent substrate for NADH:ubiquinone oxidoreductases Coumarin-Quinone Conjugate  Chemical Structure
  81. GC15877 CP 316819 Selective glycogen phosphorylase inhibitor CP 316819  Chemical Structure
  82. GC15673 CP 775146 PPARα agonist CP 775146  Chemical Structure
  83. GC10542 CP 80633 CP 80633 (CP-80,633), a cyclic nucleotide phosphodiesterase (PDE4) inhibitor, elevates plasma cyclic AMP levels and decreases tumor necrosis factor-α (TNFα) production in mice. CP 80633  Chemical Structure
  84. GC38759 CP-532623 CP-532623 is a CETP inhibitor and elevates high-density lipoprotein cholesterolion. CP-532623  Chemical Structure
  85. GC16418 CP-91149 Selective inhibitor of glycogen phosphorylase CP-91149  Chemical Structure
  86. GC48954 CP21 An iron chelator CP21  Chemical Structure
  87. GC19111 CP671305 CP671305 is a potent, orally active, selective inhibitor of phosphodiesterase-4-D, and possesses high activities. CP671305  Chemical Structure
  88. GC18258 CpdA CpdA is a non-steroidal selective glucocorticoid receptor modulator. CpdA  Chemical Structure
  89. GC14921 CPI-613 An inhibitor of α-ketoglutarate dehydrogenase CPI-613  Chemical Structure
  90. GC52278 Creatine Phosphate (sodium salt hydrate) A phosphorylated form of creatine Creatine Phosphate (sodium salt hydrate)  Chemical Structure
  91. GC45413 Cridanimod (sodium salt)   Cridanimod (sodium salt)  Chemical Structure
  92. GC43329 Cu-ATSM The metallo-protein Cu/Zn-superoxide dismutase (SOD1) is a ubiquitous enzyme responsible for scavenging superoxide radicals. Cu-ATSM  Chemical Structure
  93. GC52164 Cu-ATSP Cu-ATSP, a potent inhibitor of ferroptotic cell death, is almost 20-fold more potent than CuATSM. Cu-ATSP  Chemical Structure
  94. GC35757 Cucurbitacin D Cucurbitacin D is an active component in Cucurbita texana, disrupts interactions between Hsp90 and two co-chaperones, Cdc37 and p23. Cucurbitacin D prevents Hsp90 client (Her2, Raf, Cdk6, pAkt) maturation without induction of the heat shock response. Anti-cancer activity. Cucurbitacin D  Chemical Structure
  95. GC12043 CUDA Soluble epoxide hydrolase (sEH) inhibitor CUDA  Chemical Structure
  96. GC41611 Curcumenol Curcumenol is a sesquiterpene that has been found in Curcuma species. Curcumenol  Chemical Structure
  97. GC14787 Curcumin A yellow pigment with diverse biological activities Curcumin  Chemical Structure
  98. GC40226 Curcumin-d6 Curcumin-d6 is intended for use as an internal standard for the quantification of curcumin by GC- or LC-MS. Curcumin-d6  Chemical Structure
  99. GC10902 CVT 10216 reversible inhibitor of aldehyde dehydrogenase 2 (ALDH2) CVT 10216  Chemical Structure
  100. GC66005 CVT-11127 CVT-11127 is a potent SCD inhibitor. CVT-11127 induces apoposis and arrests the cell cycle at the G1/S phase. CVT-11127 has the potential for the research of lung cancer. CVT-11127  Chemical Structure
  101. GC31447 CVT-12012 A stearoyl-CoA desaturase inhibitor CVT-12012  Chemical Structure

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